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| 1 | Coagulation efficiency and flocs characteristics of recycling sludge during treatment of low temperature and micro-polluted water显示文摘Drinking water treatment sludge,characterized as accumulated suspended solids and organic and inorganic matter,is produced in large quantities during the coagulation process.The proper disposal,regeneration or reuse of sludge is,therefore,a significant environmental issue.Reused sludge at low temperatures is an alternative method to enhance traditional coagulation efficiency.In the present study,the recycling mass of mixed sludge and properties of raw water (such as pH and turbidity) were systematically investigated to optimize coagulation efficiency.We determined that the appropriate dosage of mixed sludge was 60 mL/L,effective initial turbidity ranges were below 45.0 NTU,and optimal pH for DOMs and turbidity removal was 6.5-7.0 and 8.0,respectively.Furthermore,by comparing the flocs characteristics with and without recycling sludge,we found that floc structures with sludge were more irregular with average size growth to 64.7 μm from 48.1 μm.Recycling sludge was a feasible and successful method for enhancing pollutants removal,and the more irregular flocs structure after recycling might be caused by breakage of reused flocs and incorporation of powdered activated carbon into larger flocs structure.Applied during the coagulation process,recycling sludge could be significant for the treatment of low temperature and micro-polluted source water. | Zhiwei Zhou Yanling Yang Xing Li Wei Gao Heng Liang Guibai Li | 2012 | Journal of Environmental Sciences2012，24，6： | 12 |
| 2 | Optimized coagulation pretreatment alleviates ultrafiltration membrane fouling: The role of floc properties and slow-mixing speed on mechanisms of chitosan-assisted coagulation显示文摘To alleviate ultrafiltration(UF) membrane fouling, the pre-coagulation of poly-aluminum chloride(PACl) with the aid of chitosan(CTS) was conducted for synthetic humic acid–kaolin water treatment. Pre-coagulation of three molecular weights(MW) CTSs(50–190 kDa(CTSL), 190–310 kDa(CTSM) and 310–375 kDa(CTSH)) was optimized with slow-mixing speeds of 30, 60 and 90 r/min, respectively. The removal efficiency and floc properties as well as membrane fouling were analyzed, and were compared to results obtained by conventional coagulation with PACl. Results showed that variations in floc properties could be ascribed to the coagulation mechanisms of CTS_L/CTS_M/CTS_H at different slow-mixing speeds, resulting in reduced UF membrane fouling. Specifically, at the low speed of 30 r/min, all three CTS types produced flocs with similar properties, while CTSLresulted in the lowest removal efficiency and aggravated irreversible fouling. At the appropriate speed of 60 r/min, CTSMgenerated the most compact flocs with the combined effects of bridging and path mechanisms. The compact cake layer formed could alleviate irreversible fouling,which was beneficial for prolonging the operation of the UF membrane. At the high speed of90 r/min, CTSHformed fragile flocs and aggravated irreversible membrane fouling. We considered membrane fouling to be affected by floc properties and the resultant removal efficiency, which was governed by the MW of the CTS used and the slow-mixing speed applied as well. | Peng Du Xing Li Yanling Yang Zhaoyang Su Hang Li Nan Wang Tingting Guo Tingting Zhang Zhiwei Zhou | 2019 | Journal of Environmental Sciences2019，31，8： | 3 |
| 3 | Modeling and test on height adjustment system of electrically-controlled air suspension for agricultural vehicles显示文摘To reduce the damages of pavement,vehicle components and agricultural product during transportation,an electric control air suspension height adjustment system of agricultural transport vehicle was studied by means of simulation and bench test.For the oscillation phenomenon of vehicle height in driving process,the mathematical model of the vehicle height adjustment system was developed,and the controller of vehicle height based on single neuron adaptive PID control algorithm was designed.The control model was simulated via Matlab/Simulink,and bench test was conducted.Results show that the method is feasible and effective to solve the agricultural vehicle body height unstable phenomenon in the process of switching.Compared with other PID algorithms,the single neuron adaptive PID control in agricultural transport vehicle has shorter response time,faster response speed and more stable switching state.The stability of the designed vehicle height adjustment system and the ride comfort of agricultural transport vehicle were improved. | Chen Yuexia Chen Long Wang Ruochen Xu Xing Shen Yujie Liu Yanling | 2016 | International Journal of Agricultural and Biological Engineering2016，9，2： | 3 |
| 4 | Changes in compressed neurons from dogs with acute and severe cauda equina constrictions following intrathecal injection of brain-derived neurotrophic factor-conjugated polymer nanoparticles显示文摘This study established a dog model of acute multiple cauda equina constriction by experimental constriction injury (48 hours) of the lumbosacral central processes in dorsal root ganglia neurons. The repair effect of intrathecal injection of brain-derived neurotrophic factor with 15 mg encapsulated biodegradable poly(lactide-co-glycolide) nanoparticles on this injury was then analyzed. Dorsal root ganglion cells (L7) of all experimental dogs were analyzed using hematoxylin-eosin staining and immunohistochemistry at 1, 2 and 4 weeks following model induction. Intrathecal injection of brain-derived neurotrophic factor can relieve degeneration and inflammation, and elevate the expression of brain-derived neurotrophic factor in sensory neurons of compressed dorsal root ganglion. Simultaneously, intrathecal injection of brain-derived neurotrophic factor obviously improved neurological function in the dog model of acute multiple cauda equina constriction. Results verified that sustained intraspinal delivery of brain-derived neurotrophic factor encapsulated in biodegradable nanoparticles promoted the repair of histomorphology and function of neurons within the dorsal root ganglia in dogs with acute and severe cauda equina syndrome. | Junming Tan Jiangang Shi Guodong Shi Yanling Liu Xiaohong Liu Chaoyang Wang Dechun Chen Shunming Xing Lianbing Shen Lianshun Jia Xiaojian Ye Hailong He Jiashun Li | 2013 | Neural Regeneration Research2013，8，3： | 2 |
| 5 | Hydrous manganese dioxide adsorbing humic acid: controlling trihalomethane formation显示文摘 | 刘锐平 Nan Jun Li Xing Yang Yanling Xia Shengji Li Guibai | 2006 | High Technology Letters2006，12，1： | 2 |
| 6 | A Feedback Scheme for Fountain Codes Based Transport Protocol in Space Communications显示文摘This paper proposed a practicalfeedback scheme for fountain codes based transportprotocol in space communications. In the proposed scheme,the sender is signaled by two types of acknowledgment(ACK) packets.Before decoding, packet loss probability isestimated on the receiver side and encapsulated intoa soft ACKand sent to the sender.After decoding,decoding results are encapsulated into hard ACKsandsent to the sender.There are two contributions in the proposed scheme: 1. Employing physical layer calculation instead of application layer statistics to estimate the packet loss probability of space channel, which can improvethe accuracy and practicality. 2. A cascade overhead-failure probabilityrelationship between the sender and the receiver has been analyzed to help determine the exact numberof packetsneeded byfountain decoding.Simulations show that for space communications,compared with the existing space transport protocols, fountain codes based transport protocolwith the proposed schemecan not only ensure transmission reliability, but also greatly improvelink utilization. | XING Yanling GE Ning | 2015 | China Communications2015，12，8： | 1 |
| 7 | Mechanism of action of Salvianolic Acid B by module-based network analysis显示文摘 | Feng Liu Ali Goodarzi Haifeng Wang Joanna Stasiak Jianbo Sun Yu Zhou Zhenzhen Ren Xing Wang Shifeng Wang Chenxi Zhai Yusu He Yanling Zhang Yanjiang Qiao | 2014 | Bio-Medical Materials and Engineering2014，，1： | 1 |
| 8 | Non-Markovian dynamics of two qubits driven by classical fields: population trapping and entanglement preservation显示文摘 | Xiao Xing Fang Maofa Li Yanling | 2010 | J Phys B: At Mol Opt2010，43，18： | 1 |
| 9 | Resource-constrained maximum network throughput on space networks显示文摘This paper investigates the maximum network throughput for resource-constrained space networks based on the delay and disruption-tolerant networking(DTN) architecture. Specifically,this paper proposes a methodology for calculating the maximum network throughput of multiple transmission tasks under storage and delay constraints over a space network. A mixed-integer linear programming(MILP) is formulated to solve this problem. Simulations results show that the proposed methodology can successfully calculate the optimal throughput of a space network under storage and delay constraints, as well as a clear, monotonic relationship between end-to-end delay and the maximum network throughput under storage constraints. At the same time, the optimization results shine light on the routing and transport protocol design in space communication, which can be used to obtain the optimal network throughput. | Yanling Xing Ning Ge Youzheng Wang | 2015 | Journal of Systems Engineering and Electronics2015，26，2： | 1 |
| 10 | The removal characteristics of natural organic matter in the recycling of drinking water treatment sludge:Role of solubilized organics显示文摘 | Zhou Zhiwei Yang Yanling Li Xing | 2016 | Ultrasonics Sonochemistry2016，，28： | 1 |
| 11 | The oxidative and adsorptive effectiveness of hydrous manganese dioxide for arsenite removal显示文摘 | 刘锐平 Yuan Baoling Li Xing Xia Shengji Yang Yanling Li Guibai | 2006 | High Technology Letters2006，12，3： | 0 |
| 12 | Observation on the Effect of Integrated Medical and Nursing Care in Patients with Pulmonary Tuberculosis Combined with Lung Cancer显示文摘Objective:To explore the effect of integrated medical and nursing care in patients with pulmonary tuberculosis combined with lung cancer.Methods:From August 2021 to August 2022,60 patients with pulmonary tuberculosis combined with lung cancer were admitted.All patients were diagnosed with pulmonary tuberculosis according to the Guidelines for the Diagnosis and Treatment of Pulmonary Tuberculosis and with lung cancer by pathology.The patients were randomly divided into two groups,with 30 cases in each group.The control group received daily nursing care,whereas the study group received integrated medical and nursing care.The sputum conversion rate,tumor remission rate,and quality of life of patients were observed and analyzed.Results:The item function score and symptom function score of the observation group were higher than those of the control group(P<0.05);the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);the sputum conversion rate of the observation group was significantly higher than that of the control group(P<0.05).Conclusion:For patients with pulmonary tuberculosis combined with lung cancer,the application of integrated medical and nursing care can help consolidate the treatment effect and improve the quality of life of patients;thus,it is worthy of promotion and application. | Wei Yuan Yuanyuan Lu Mi Zhang Min Zheng Xing Luan Yanling Feng Linlin Chai | 2023 | Proceedings of Anticancer Research2023，7，3： | 0 |
| 13 | Clinical Efficacy of the Integrated Medical Care Model Combined with Psychological Intervention in Tuberculosis Patients with Lung Cancer显示文摘Objective:To explore the clinical efficacy of the integrated medical care model combined with psychological intervention in pulmonary tuberculosis patients with lung cancer.Methods:From January to December 2022,60 pulmonary tuberculosis patients with lung cancer admitted to our hospital were selected as the research subjects.Using the random number table method,the patients were divided into two groups,a control group and a study group,with 30 cases in each group.The chest computed tomography(CT)examination results,mental state assessment(including depression scale and anxiety scale)scores,incidence of adverse reactions,treatment effect,and length of hospital stay were compared between the two groups.Results:The treatment effect of the patients in the study group was better than that of the patients in the control group(P<0.05);the duration of hospitalization,chest CT examination results,mental state assessment scores,and incidence of adverse reactions of the study group and the control group,were significantly different(P<0.05).Conclusion:The integrated medical care model combined with psychological intervention can effectively improve the treatment effect of pulmonary tuberculosis patients with lung cancer and prevent the occurrence of adverse reactions;thus,it should be promoted in clinical practice. | Wei Yuan Dandan Yang Xinyi Ye Zhangying Li Xing Luan Min Zheng Yanling Feng Mi Zhang Chuo Guo | 2023 | Journal of Clinical and Nursing Research2023，7，2： | 0 |
| 14 | Dispen-Seq: a single-microparticle dispenser based strategy towards flexible cell barcoding for single-cell RNA sequencing显示文摘Single-cell RNA sequencing(sc RNA-seq)has become one of the most powerful tools to understand the heterogeneity of biological systems.While barcoding strategies have revolutionized the field of high-throughput sc RNA-seq,it is still challenging to achieve highly efficient,direct and universal cell barcoding with cost-effectiveness and minimal sample loss.Herein,a single micro-particle dispenser approach for rapid single barcode bead/cell manipulation and pairing,enabling highly efficient cell barcoding for sc RNA-seq(Dispen-Seq)was developed.Notably,Dispen-Seq provides a versatile platform which can enrich cell subgroups of interest while unlimited by input sample amounts,and can respond to changes in sample composition with high resolution and reproducibility.It is anticipated that Dispen-Seq will increase the scope of sc RNA-seq from academic research to practical applications. | Tian Tian Yingwen Chen Yunpeng Bi Xingrui Li MingXuan Gao Xuebing Zhang Weidong Ruan Jia Song Xing Xu Lingling Wu Zhi Zhu Yanling Song Chaoyong Yang | 2021 | Science China Chemistry2021，64，4： | 0 |
| 15 | Optimized photocatalytic regeneration of adsorption-photocatalysis bifunctional composite saturated with Methyl Orange显示文摘Photo-responsive adsorption-photocatalysis nanocomposites are generally used in water and wastewater decontamination;however,the prolonged adsorption capacity of composites and the role of adsorption in concomitant photocatalysis are typically neglected.These composites can be regenerated under light irradiation as their adsorption capacity decreases.Herein,a novel adsorption-photocatalysis bifunctional nanocomposite,Bi-doped TiO2 supported on powdered activated carbon(Bi2O3/TiO2/PAC),was prepared using the solimpregnation-hydrothermal procedure.Bi2O3/TiO2/PAC with a secondary calcination temperature of 700℃under a nitrogen atmosphere was selected for maximum adsorption capacity on Methyl Orange(MO).The composite displayed an excellent adsorption capacity and was easily separated and recycled.The results demonstrate that 71.2%photocatalytic regeneration efficiency could be attained under visible light irradiation for 1 hr at an intensity of 750 W/m^2 and pH 7.Characterization of the as-prepared Bi2O3/TiO2/PAC nanocomposite(700℃)indicates that it possesses a highly specific surface area and great optical properties,showing bifunctional adsorption-photocatalysis characteristics.The p-n heterojunction of the composite played a dominant role in the photocatalytic regeneration process,and effective degradation of MO could be achieved along with composite regeneration. | Yi Shang Xing Li Yanling Yang Nan Wang Xiaoxuan Zhuang Zhiwei Zhou | 2020 | Journal of Environmental Sciences2020，32，8： | 0 |
| 16 | In silico investigation of the association of the TRPM8 ion channel with the pungent flavor of Chinese herbs显示文摘Objective:Explicating the property and action of traditional Chinese medicine(TCM)in the perspectives of modern science deepens the insight into the property of TCM,and provides the basis for new drug discovery and clinical therapy.In this study,we investigated the relationship between transient receptor potential melastatin 8(TRPM8)and pungent flavor using three-dimensional pharmacophores based on virtual screening methods.Methods:Firstly,an inhouse database was established to identify the related pharmacological action according to the traditional Chinese herbs expressing an action of promoting blood circulation.Then,several therapeutic targets,3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMG-CoAR),cholesteryl ester transfer protein(CETP),Niemann-Pick C1-Like 1(NPC1L1)and platelet-activating factor receptor(PAFR),were selected to screen traditional Chinese herbs,and the common virtual screening hits with various hit scores providing data to reveal the correlation among TRPM8 and therapeutic targets.Results:According to the screening results,TRPM8 agonists were able to identify the effective components of pungent herbs and TRPM8,which shares the common virtual screening hits with the therapeutic targets,was considered to be related to the action of pungent taste.Conclusion:The novel ideas and methods in this study are beneficial to unveil the scientific relationship between a TCM property and its action. | Yuxin Zhang Xing Wang Shifeng Wang Qiao Zhang Sha Peng Xi Li Yanling Zhang Yanjiang Qiao | 2016 | Journal of Traditional Chinese Medical Sciences2016，3，4： | 0 |
| 17 | Functional and binding studies of gallic acid showing platelet aggregation inhibitory effect as a thrombin inhibitor显示文摘Objective:This study was devoted to identifying natural thrombin inhibitors from traditional Chinese medicine(TCM)and evaluating its biological activity in vitro and binding characteristics.Methods:A combination strategy containing molecular docking,thrombin inhibition assay,surface plasmon resonance(SPR)and molecular dynamics simulation were applied to verify the study result.Results:Gallic acid was confirmed as a direct thrombin inhibitor with IC;of 9.07μmol/L and showed a significant inhibitory effect on thrombin induced platelet aggregation.SPR-based binding studies demonstrated that gallic acid interacted with thrombin with a KDvalue of 8.29μmol/L.Molecular dynamics and binding free energy analysis revealed that thrombin-gallic acid system attained equilibrium rapidly with very low fluctuations,the calculated binding free energies was-14.61 kcal/mol.Ala230,Glu232,Ser235,Gly258 and Gly260 were the main amino acid residues responsible for thrombin inhibition by gallic acid,providing a mechanistic basis for further optimization.Conclusion:This study proved that gallic acid is a direct thrombin inhibitor with platelet aggregation inhibitory effect,which could provide a basis for the follow-up research and development for novel thrombin inhibitors. | Yuxin Zhang Xing Wang Binan Lu Yanbin Gao Yanling Zhang Yatong Li Hongjuan Niu Lu Fan Zongran Pang Yanjiang Qiao | 2022 | Chinese Herbal Medicines2022，14，2： | 0 |
| 18 | Technology and management innovation of the first-of-a-kind (FOAK) demonstration project — HPR1000显示文摘1 Project overview As a result of 60 years of independent innovation of China’s nuclear industry,Hualong One nuclear reactor(hereafter referred to as HPR1000,see Fig.1)is developed based on 30 years of experience in nuclear power research,design,manufacturing,construction and operation with the world’s advanced nuclear power concept and feedback from previous nuclear accidents.With more than 100 scientific research projects completed,HPR1000 has finally become a success as a 1000 MW Gen III nuclear power technology with completely independent intellectual property rights.It has met or exceeded requirements of international Gen III nuclear power users in terms of safety,economy and performance indicators,making China jump into the ranks of advanced countries of nuclear power technology. | Ji XING Tianlei ZHEN Hang YU Yanling ZHENG | 2021 | Frontiers of Engineering Management2021，8，3： | 0 |
| 19 | Functional evaluation of the insulin/insulin-like growth factor signaling pathway in determination of wing polyphenism in pea aphid显示文摘Wing polyphenism is a common phenomenon that plays key roles in environmental adaptation of insects.Insulin/insulin-like growth factor signaling(IIS)pathway is a highly conserved pathway in regulation of metabolism,development,and growth in metazoans.It has been reported that IS is required for switching of wing morph in brown planthopper via regulating the development of the wing pad.However,it remains elusive whether and how IIS pathway regulates transgenerational wing dimorphism in aphid.In this study,we found that pairing and solitary treatments can induce pea aphids to produce high and low percentage winged offspring,respectively.The expression level of ILP5(insulin-like peptide 5)in maternal head was significantly higher upon solitary treatment in comparison with pairing,while silencing of ILP5 caused no obvious change in the winged offspring ratio.RNA interference-mediated knockdown of FoxO(Forkhead transcription factor subgroup O)in stage 20 embryos significantly increased the winged offspring ratio.The results of pharmacological and quantitative polymerase chain reaction experiments showed that the embryonic insulin receptors may not be involved in wing polyphenism.Additionally,ILP4 and ILP11 exhibited higher expression levels in 1st wingless offspring than in winged offspring.We demonstrate that FoxO negatively regulates the wing morph development in embryos.ILPs may regulate aphid wing polyphenism in a developmental stage-specific manner.However,the regulation may be not mediated by the canonical IIS pathway.The findings advance our understanding of IIS pathway in insect transgenerational wing polyphenism. | Yiyang Yuan Yanyan Wang Wanwan Ye Erliang Yuan Jian Di Xin Chen Yanling Xings Yucheng Sun Feng Ge | 2023 | Insect Science2023，30，3： | 0 |
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