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| 1 | Expression of IL-1α, IL-6, TGF-β, FasL and ZNF265 During Sertoli Cell Infection by Ureaplasma Urealyticum显示文摘 | Rongping Li Yebin Xi Xiuzhi Liu Guangjie Chen Baoguo Wang Lihua Jiang Weiyi Li | 2009 | Cellular & Molecular Immunology2009，6，3： | 8 |
| 2 | Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin显示文摘在动脉粥样硬化的发展评估 ghrelin 的可能的角色,它肿瘤上的效果脉管的光滑的肌肉房间(VSMC ) 的坏死因素(TNF )-α-induced 增长和 apoptosis 被调查。老鼠 VSMC 是有 ghrelin 的不同集中然后与 TNF-α 的 pretreated。VSMC 增长被 3-(4,5-dimethylthiazol-2-yl ) 测量 -2,5-diphenyl tetrazolium 溴化物试金和流动 cytometry 方法。Apoptosis 用 propidium 碘化物和 Annexin-V 标记方法被检测。外长的 ghrelin (10-1000 ng/ml ) 显著地以一种集中依赖者方式禁止了 VSMC 的 TNF-α-induced 增长。有 1000 ng/ml ghrelin 的处理在禁止 VSMC 增长率和增殖的房间的表示是很有效的原子抗原。然而,有 des 酰 ghrelin 的处理影响了既不增长也不 PCNA 表示。相反, VSMC 的 TNF-α-induced apoptosis 被 ghrelin 和 des 酰 ghrelin 在集中依赖者礼貌禁止,与为在 1000 ng/ml 的两混合物观察的最大的抑制。总起来说,我们的结果建议 ghrelin 禁止了老鼠 VSMC 的增长和 apoptosis。而且,以前的效果被生长荷尔蒙促泌素受体类型 la 受体可能调停,当后者效果可以通过另外的受体被调停时。 | Min Zhang Fang Yuan Hua Liu Hui Chen Xingbiao Qiu Weiyi Fang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，9： | 8 |
| 3 | Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9显示文摘In this study,we present novel molecular mechanisms by which FOXO1 functions as a tumor suppressor to prevent the pathogenesis of nasopharyngeal carcinoma(NPC).First,we observed that FOXO1 not only controlled tumor stemness and metastasis,but also sensitized NPC cells to cisplatin(DDP)in vitro and in vivo.Mechanistic studies demonstrated that FOXO1-induced miR-200b expression through the GSK3β/β-catenin/TCF4 network-mediated stimulation of ZEB1,which reduced tumor stemness and the epithelial–mesenchymal transition(EMT)signal.Furthermore,we observed FOXO1 interaction with MYH9 and suppression of MYH9 expression by modulating the PI3K/AKT/c-Myc/P53/miR-133a-3p pathway.Decreased MYH9 expression not only reduced its interactions with GSK3β,but also attenuated TRAF6 expression,which then decreased the ubiquitin-mediated degradation of GSK3βprotein.Increased GSK3βexpression stimulated theβ-catenin/TCF4/ZEB1/miR-200b network,which increased the downstream tumor stemness and EMT signals.Subsequently,we observed that chemically synthesized cinobufotalin(CB)strongly increased FOXO1-induced DDP chemosensitivity by reducing MYH9 expression,and the reduction in MYH9 modulated GSK3β/β-catenin and its downstream tumor stemness and EMT signal in NPC.In clinical samples,the combination of low FOXO1 expression and high MYH9 expression indicated the worst overall survival rates.Our studies demonstrated that CB potently induced FOXO1-mediated DDP sensitivity by antagonizing its binding partner MYH9 to modulate tumor stemness in NPC. | YongHao Li Xiong Liu Xian Lin Menyang Zhao Yanyi Xiao Chen Liu Zixi Liang Zelong Lin Renhui Yi Zibo Tang Jiahao Liu Xin Li Qingping Jiang Libo Li Yinyin Xie Zhen Liu Weiyi Fang | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 6 |
| 4 | Size-controlled MoS2 nanodots supported on reduced graphene oxide for hydrogen evolution reaction and sodium-ion batteries显示文摘转变金属 dichalcogenide nanodots (ND ) 收到了可观的兴趣。我们由在 oleylamine 把铝 pentachloride 和 L 半胱氨酸用作先锋为瞬间 2 ND 报导一条灵巧的自底向上的合成线路。有从 2.2 ~ 5.3 nm 的狭窄的尺寸分布的 ND 的合成,被控制反应时间定制。因为它的涂层特征, oleyalmine 导致 ND 的一致性和 monodispersity。而且, ND 综合了有大特定的表面区域提供活跃地点。Graphene 拥有突出的电导率。联合二材料的优点,因为 2D, 0D/2D 材料展出优异电气化学的性能为离子吸附,精力存储,和变换的可渗透的隧道。同样准备的瞬间 2/rGO (~ 2.2 nm ) 显示出 220 mAhroscopy 分析的一个稳定的能力。与另外的报导金属 oxide/CN composites 比较,有 TiO 2 nanoparticles 的 ultrathin CN-NSs 层的强壮的相互作用制止他们的重新叠,哪个导致 234.0 m 2 的一个大特定的表面区域吗? | Weiyi Sun Pan Li Xue Liu Jiajia Shi Hongming Sun Zhanliang Tao Fujun Li Jun Chen | 2017 | Nano Research2017，10，7： | 6 |
| 5 | PROPAGATION BEHAVIORS OF SHEAR HORIZONTAL WAVES IN PIEZOELECTRIC-PIEZOMAGNETIC PERIODICALLY LAYERED STRUCTURES显示文摘This paper investigates shear horizontal(SH) waves propagating in a periodically layered structure that consists of piezoelectric(PE) layers perfectly bonded with piezomagnetic(PM) layers alternately.The explicit dispersion relations are derived for the two cases when the propagation directions of SH waves are normal to the interface and parallel to the interface,respectively.The asymptotic expressions for dispersion relations are also given when the wave number is extremely small.Numerical results for stop band effect and phase velocity are presented for a periodic system of alternating BaTiO3 and Terfenol-D layers.The influence of volume fraction on stop band effect and dispersion behaviors is discussed and revealed. | Jinxi Liu Weiyi Wei Daining Fang | 2010 | Acta Mechanica Solida Sinica2010，23，1： | 5 |
| 6 | Microstructure and properties of novel Al-Ce-Sc,Al-Ce-Y,Al-Ce-Zr and Al-Ce-Sc-Y alloy conductors processed by die casting,hot extrusion and cold drawing显示文摘In order to overcome the trade-off between the strength and electrical conductivity of aluminum alloy conductors,the new Al-Ce-Sc,Al-Ce-Y,Al-Ce-Zr and Al-Ce-Sc-Y alloys were prepared by die casting,high temperature homogenization treatment,hot extrusion and cold drawing.Adding Sc and Y eliminated the dendrite segregation of the as-cast Al-0.2 Ce alloy and promoted the formation of equiaxed grains with the average grain size of 142.5μm.The Al-0.2 Ce-0.2 Sc-0.1 Y alloy inherited the great tensile properties of Al-0.2 Ce-0.2 Sc alloy and the high electrical conductivity of Al-0.2 Ce-0.1 Y alloy simultaneously.After cold drawing and annealing at 200℃for 5 h,the ultimate tensile strength of Al-0.2 Ce-0.2 Sc-0.1 Y alloy reached 200 MPa and 198 MPa,the elongation reached 6.8%and 8.5%,and the electrical conductivity reached 61.01%and 61.77%,respectively.The main second phase of Al-0.2 Ce-0.2 Sc-0.1 Y alloy after hot extrusion were Al_(13)Fe_3 Ce containing a few Y and Si atoms.The larger size and proportion of the second phase greatly reduced the concentration of solute Fe and Si atoms and the addition of Y significantly decreased the density of defects after cold drawing compared to Al-0.2 Ce-0.2 Sc alloy,which improved electrical conductivity of the alloy.Furthermore,the dispersed and coherent nano-size Al_3 Sc precipitions of Al-0.2 Ce-0.2 Sc-0.1 Y alloy greatly improved strength,elongation and heat resistance.Compared with Al-0.2 Ce-0.2 Sc alloy,the lower density of dislocation,stacking fault and subgrain boundary and the larger size of Al_3 Sc precipitions with enrichment of Y atoms enable the Al-0.2 Ce-0.2 Sc-0.1 Y alloy to maintain high strength,elongation and electrical conductivity after annealing. | Weiyi Wang Qinglin Pan Geng Lin Xiaoping Wang Yuqiao Sun Xiangdong Wang Ji Ye Yuanwei Sun Yi Yu Fuqing Jiang Jun Li Yaru Liu | 2020 | Journal of Materials Science & Technology2020，58，23： | 4 |
| 7 | THE BOUNDEDNESS OF CERTAIN OPERATORS ON HOLDER AND SOBOLEV SPACES显示文摘The main topic in this note is to discuss the boundedness of pseudo-differential operators and para-product nptfators on ihe Holder and Sobotev space;, respectively It is the preparation of the thoery of Gibbs - Butzer deffereftital operators and differential equations. | Su Weiyi (Nanjing University,China)Liu Guangqi (Huabei Electronic Faculty University,China) | 1997 | Analysis in Theory and Applications1997，13，1： | 4 |
| 8 | Alzheimer's disease treated with combined therapy based on nourishing marrow and reinforcing Qi显示文摘OBJECTIVE:To study the efficacy and safety of combined Traditional Chinese Medicine(TCM) therapy based on nourishing marrow to improve intellect and reinforcing Qi to activate bloodon mild to moderate Alzheimer's disease(AD).METHODS:Sixty-six patients with AD,whoseMini-Mental State Examination(MMSE) score were from 10-24,were randomized equally into an intervention group and a control group.The control group was given Aricept(5 mg,once daily).The intervention group was further divided into Yang-Qi deficiency(n = 18) and of Yin-Qi deficiency(n = 15)subgroups.Patients in the Yang-Qi deficiency group were intravenously administered Shenfu injection,60 mL,and deproteinized calf blood injection(DCBl),1.2 g,once daily.The Yin-Qi deficiency group was given Shenmai injection,60 mL,and DCBl,1.2 g,once daily.Each course lasted 21 days.RESULTS:Compared with the control group and with pre-treatment in the same group,MMSE,clinical dementia rating,and activities of daily living scale scores in the intervention group were significantly improved(all P<0.05).These metrics mildly improved in the control group compared with before treatment(P>0.05).No adverse effects were observed in any group during treatment.CONCLUSION:We found that combined TCM therapy is effective and safe for managing mild to moderate AD. | Chen Songlin Yao Xiaoli Liang Yinying Mei Weiyi Liu Xiaoyun Zhang Changran | 2015 | Journal of Traditional Chinese Medicine2015，35，3： | 4 |
| 9 | Simulation of Centennial-Scale Drought Events over Eastern China during the Past 1500 Years显示文摘The characteristics and causes of centennial-scale drought events over eastern China during the past 1500 years were explored based on simulations of the Community Earth System Model(CESM). The results show that centennial-scale drought events over eastern China occurred during the periods of 622–735(Drought period 1, D1) and 1420–1516(Drought period 2,D2) over the past 1500 years, which is comparable with climate proxy data. In D1, the drought center occurred in northern China and the Yangtze River valley; however, in southern China, precipitation was much more than usual. In D2, decreased precipitation was found across almost the whole region of eastern China. The direct cause of these two drought events was the weakened East Asian summer monsoon, and the specific process was closely linked to the air–sea interaction of the Indo-Pacific Ocean. In D1, regions of maximum cooling were observed over the western Pacific, which may have led to anomalous subsidence, weakening the Walker circulation, and reducing the northward transport of water vapor. Additionally, upward motion occurred over southern China, strengthening convection and increasing precipitation. In D2, owing to the decrease in the SST, subsidence dominated the North Indian Ocean, blocking the low-level cross-equatorial flow, enhancing the tropical westerly anomalies, and reducing the northward transport of moisture. Additionally, descending motion appeared in eastern China, subsequently decreasing the precipitation over the whole region of eastern China. The anomalous cooling of the Indo-Pacific Ocean SST may have been caused by the persistently low solar irradiation in D1; whereas, in D2,this characteristic may have been influenced not only by persistently low solar irradiation, but frequent volcanic eruptions too. | Weiyi SUN Jian LIU Zhiyuan WANG | 2017 | Journal of Meteorological Research2017，31，1： | 4 |
| 10 | Wafer-scale arrayed p-n junctions based on few-layer epitaxial GaTe显示文摘二维(2D ) 材料吸引了实质的注意在电子并且有灵活、透明、高度悦耳的优异优点的 optoelectronic 应用。当时,无差距的 graphene 展出极端宽带、快的 photoresponse 半导体的瞬间 2 和门高展出的 2D 敏感和悦耳的 responsivity 到可见的光。然而,设备收益和重覆性打电话让进一步的改进完成大规模一致性。这里,我们与 28.4 厘米 2/(V0 的高洞活动性报导晶片规模门的 layer-by-layer | Xiang Yuan Lei Tang Peng Wang Zhigang Chen Yichao Zou Xiaofeng Su Cheng Zhang Yanwen Liu Weiyi Wang Cong Liu Fansheng Chen Jin Zou Peng Zhou Weida Hu Faxian Xiu | 2015 | Nano Research2015，8，10： | 4 |
| 11 | Separation process of butanol-butyl acetate-methyl isobutyl ketone system by the analysis to residual curve and the double effect pressure-swing distillation显示文摘The separation of ternary mixture of butanol, butyl acetate, and methyl isobutyl ketone(MIBK) was initially analyzed by the residual curve. In this process, MIBK was chosen as the azeotropic agent during the first step of separation. The optimum mass ratio of extra MIBK was 1.6 in the modified feed stream according to the residual curve. Thus on this condition the top product was butanol-MIBK azeotrope while the bottom product was butyl acetate in the preliminary separation of the mixture. Then the butanol and MIBK azeotrope was separated by the double effect pressureswing distillation with the low pressure column performing at 30 kPa and the atmospheric pressure column at 101 kPa. The optimal operating conditions were then obtained by using Aspen Plus to simulate and optimize the process. The results showed that the mass purities of butanol, butyl acetate, and MIBK were all more than 99% and reached the design requirements. Additionally, compared with the traditional distillation with outside heating, the double effect pressure swing distillation saved the reboiler duty by 48.6% and the condenser duty by 44.6%. | Chunli Li Yuanyuan Song Jing Fang Yang Liu Weiyi Su Yuqi Hu | 2017 | Chinese Journal of Chemical Engineering2017，25，3： | 4 |
| 12 | A review on analytical methods for pharmaceutical and personal care products and their transformation products显示文摘Pharmaceutical and personal care products(PPCPs)and corresponding transformation products have caused widespread concern due to their persistent emissions and potential toxicity.They have wide octanol-water partition coefficients(K_(ow))and different ionization constants(pK_(a))resulting in a poor analysis accuracy and efficiency.A suitable analytical method is the first prerequisite for further research on their environmental behavior to prioritize the substances.This study reviewed a full-scale analytical protocol for environmental samples in the recent ten years:from sampling to instrumental methods.Passive sampling techniques were compared and recommended for long-term continuous and scientific observation.A quick and effective sample extraction and clean-up method are highly required.Chromatographic methods coupled to mass spectrometry for determining PPCPs with a wide range of logK_(ow)(-7.53 to 10.80)were summed up.High-resolution mass spectrometry was confirmed to be a promising strategy for screening unknown transformation products,which would provide a nanogram level of detection limits and more accurate mass resolution.Screening strategies and mass change principles were summarized in detail.The recovery rate was important in multiple contaminants analysis identification and factors affecting the recovery rate of PPCPs were also discussed in this review,including sample matrix,target compounds characteristics,extraction method and solid-phase adsorbent.This review provides useful information for the selection of appropriate analytical methods and future development directions. | Yuan Meng Weiyi Liu Xiaohui Liu Jinlan Zhang Meng Peng Tingting Zhang | 2021 | Journal of Environmental Sciences2021，33，3： | 3 |
| 13 | Long-term exposure to decabrominated diphenyl ether mpairs CD8 T-cell function in adult mice显示文摘 | Weihong Zeng Ying Wang Zhicui Liu Asma Khanniche Qingliang Hu Yan Feng Weiyi Ye Jianglong Yang Shujun Wang Lin Zhou Hao Shen Yan Wang | 2014 | Cellular & Molecular Immunology2014，11，4： | 3 |
| 14 | Boosted photoreduction of diluted CO_(2) through oxygen vacancy engineering in NiO nanoplatelets显示文摘Converting carbon dioxide(CO_(2))to diverse value-added products through photocatalysis can validly alleviate the critical issues of greenhouse effect and energy shortages simultaneously.In particular,based on practical considerations,exploring novel catalysts to achieve efficient photoreduction of diluted CO_(2) is necessary and urgent.However,this process is extremely challenging owing to the disturbance of competitive adsorption at low CO_(2) concentration.Herein,we delicately synthesize oxygen vacancy-laden NiO nanoplatelets(r-NiO)via calcination under Ar protection to reduce diluted CO_(2) through visible light irradiation(>400 nm)assisted by a Ru-based photosensitizer.Benefitting from the strongly CO_(2) adsorption energy of oxygen vacancies,which was confirmed by density functional calculations,the r-NiO catalysts exhibit higher activity and selectivity(6.28×10^(3)µmol·h^(−1)·g^(−1);82.11%)for diluted CO_(2)-to-CO conversion than that of the normal NiO(3.94×10^(3)µmol·h^(−1)·g^(−1);65.26%).Besides,the presence of oxygen vacancies can also promote the separation of electron-hole pairs.Our research demonstrates that oxygen vacancies could act as promising candidates for photocatalytic CO_(2) reduction,offering fundamental guidance for the actual photoreduction of diluted CO_(2) in the future. | Weiyi Chen Xueming Liu Bin Han Shujie Liang Hong Deng Zhang Lin | 2021 | Nano Research2021，14，3： | 2 |
| 15 | Asymmetries of Positive Feedback Trading in Individual Stocks:Evidences from China显示文摘The paper investigates the positive feedback trading phenomenon of individual stocks in China’s stock market.Heterogeneous regression models and a non-parametric Sentana-Wadhwani model are developed and applied to prove the existence of rise-favor asymmetric feedback trading.This result is consistent with the reality of China’s stock market,that is,the herding behavior of irrational retail investors has a significant influence on the market.However,the result is in contrast with the stylized findings using market indices.Further empirical research shows that this distinction could be explained by the average effect of indices.The asymmetries of positive feedback trading caused by heterogeneous feedback trading and the uneven distributed retail trading in individual stocks,are covered by the weighted average effect in indices.Therefore,the indices exhibit a different asymmetric pattern from that of individual stocks. | Die Wan Weiyi Liu Junbo Wang Xiaoguang Yang | 2016 | Journal of Management Science and Engineering2016，1，1： | 2 |
| 16 | Enhancement of radiosensitivity of lung adenocarcinoma using a decoction from the Fuzhengzengxiao formula显示文摘OBJECTIVE: To study the effects of a decoction of Fuzhengzengxiao formula on lung adenocarcinoma regarding the inflammatory protein S100A9 known to enhance cancer cell sensitivity.METHODS: A nude mouse model of human lung adenocarcinoma was established. The mice were randomly divided into four groups using the random number table method: Group Ⅰ, control;Group Ⅱ, treatment with a decoction of the Fuzhengzengxiao formula alone; Group Ⅲ, treatment with radiotherapy alone; and Group Ⅳ, treatment with radiotherapy plus a decoction of Fuzhengzengxiao formula. When the tumor body was 1 cm^3 in diameter, the tumor bearing mice in GroupsⅢ and Ⅳ were irradiated at a single dose of 10 Gy and the tumor inhibition rate was evaluated.The expression of S100A9 was determined using Western blotting and q-PCR(Real-time Quantitative PCR Detecting System). The sensitivity of cells containing RNAi S100A9 to radiotherapy was evaluated using the Click multiple target model,and the cell cycle was analyzed using flow cytometry.RESULTS: Relative to the control group,the expression of S100A9 in the tumors in each treatment group was decreased,especially in Group Ⅳ. The sensitizing enhancement ratio(SER) Dq was >1 after RNAi S100A9; it decreased the surviving fraction after a 2 Gy dose exposure,and also the D_0 and Dq of the tumor cells; in addition, the radiosensitivity of G_2/M cells was significantly increased.CONCLUSION: The decoction of the Fuzhengzengxiao formula downregulated the expression of S100A9 in lung adenocarcinoma cells. | Zhang Qiaoli Wu Tong Lei Yong Li Bo Liu Weiyi Tian Yehong Zhao Weipeng Huang Jingchang | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 2 |
| 17 | Molecular cloning and mRNA expression of duck invariant chain显示文摘 | Dalian Zhong Weiyi Yu Min Bao Zhiben Xu Lin Li Jing Liu | 2005 | Veterinary Immunology and Immunopathology2005，，3： | 1 |
| 18 | Molecular cloning and expression of two chicken invariant chain isoforms produced by alternative splicing显示文摘 | Dalian Zhong Weiyi Yu Yuhua Liu Jing Liu Jinnian Li | 2004 | Immunogenetics2004，，9： | 1 |
| 19 | Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-[beta]-like signaling pathway显示文摘 | Ding Lihua Wang Zhaoyun Yan Jinghua Yang Xiao Liu Aijun Qiu Weiyi Zhu Jianhua Han Juqiang Zhang Hao Lin Jing Cheng Long Qin Xi Niu Chang Yuan Bin Wang Xiaohui Zhu Cui Zhou Yan Li Jiezhi Song Haifeng Huang Cuifen Ye Qinong | 2009 | Journal of Clinical Investigation2009，，2： | 1 |
| 20 | A statistical method for estimating the usefulness of text databases显示文摘 | Liu King-Lup Yu Clement Meng Weiyi | 2002 | IEEE Transactionson Knowledge and Data Engineering2002，14，6： | 1 |
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