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4篇 您的检索式:作者名="Weipeng Mao"
    题名 作者 年代 出处 被引量
1Supramolecular Vesicles Based on Water-Soluble 2,6-Helic[6]arene:High Affinity Binding,Stimuli Responsiveness and Delivery of Doxorubicin to Cancer Cells显示文摘Water-soluble 2,6-helic[6]arene was used to construct supramolecular vesicles via host-guest interaction. Water-soluble 2,6-helic[6]arene was discovered to be high affinity host for suitable biomarkers. Supramolecular vesicles were responsive to multiple stimuli types, including temperature, pH, Ca^2+, CO2 bubbling and biomarker displacement. Supramolecular vesicles were used to load and deliver anti-tumor drug doxorubicin to HeLa cells in vitro.Xuan Yang Weipeng Mao Yamin Liu Libai Li Da Ma 2019Chinese Journal of Chemistry2019,37,6:1
2AND molecular logic gates based on host-guest complexation operational in live cells显示文摘We report supramolecular AND logic gates based on host-guest complexation between acid-labile acyclic cucurbit[n]uril(CB[n]) molecular container and Na Cl O-responsive dye. Supramolecular AND logic gate is turned on due to acid-triggered degradation of molecular container and the release of the dye, followed by Na Cl O-induced fluorescence “switch on” effect of the dye. The reason for AND molecular logic gate is discovered to be the combination of oxidation inhibition and fluorescence “switch off” effect. Supramolecular AND logic gate is confirmed to be operational in live MCF-7 and He La cancer cells.Siyang Jiang Weipeng Mao Dake Mao Zhan-Ting Li Da Ma 2022Chinese Chemical Letters2022,33,2:1
3Smart supramolecular vesicles based on glutathione-reactive pillar[6]arene and acid-labile prodrug:Dual drug loading and sequential release显示文摘Glutathione thiol-reactive pillar[6]arene(TWP6)is designed and synthesized as the first example of reducing agent-reactive host molecule.TWP6 shows high affinity binding towards suitable anti-tumor drugs and guests.Doxorubicin-based acid-labile prodrugs and TWP6 are used to construct supramolecular vesicles,which are also loaded with camptothecin.The supramolecular vesicles loaded with two drugs demonstrate glutathione-and acid-responsive drug release as well as sequential release to both stimuli types.Supramolecular vesicles show combination therapeutic effect towards tumor cells in vitro.Yamin Liu Siyang Jiang Weipeng Mao Pintao Li Fang Zhou Da Ma 2022Chinese Chemical Letters2022,33,1:0
4HCS: Expanding H-Code RAID 6 without Recalculating Parity Blocks in Big Data Circumstance显示文摘This paper introduces a new RAID 6 expanding method HCS, which is facing the circumstance of big data. HCS expands H-Code manner RAID 6. Two key techniques are used to avoid parity blocks’ recalculating.The first one is anti-diagonal data blocks’ selection, and the other one is horizontal data migration. These two techniques ensure the data blocks are retained in the same verification zone, that is horizontal verification zone and anti-diagonal verification zone. Experimental results showed that, compared with SDM, which is also a fast expansion method, HCS can reduce 3.6% expansion time and promote 4.62% performance under four traces.Shiying Xia Yu Mao Minsheng Tan Weipeng Jing 2015国际计算机前沿大会会议论文集2015,,1:0
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