4篇
您的检索式：作者名="Waqar Ahmad Kaleem"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | In vivo screening of essential oils of Skimmia laureola leaves for antinociceptive and antipyretic activity显示文摘Objective:To study the screening of essential oils of Skimmia laureola leaves(SLO)for acute toxicity,antinociceptive,antipyretic and anticonvulsant activities in various animal models.Methods:SLO were extracted using modified Clevenger type apparatus.Acute toxicity test was used in mice to observe its safety level.Antinociceptive activity of SLO was evaluated in acetic acid induced writhing and hot plate tests.Yeast induced hyperthermic mice and pentylenetetrazole induced convulsive mice were used for the assessment of its antipyretic and anticonvulsant profile respectively.Results:Substantial safety was observed for SLO in acute toxicity test.SLO showed a high significant activity in acetic acid induced writhing test in a dose dependent manner with maximum pain attenuation of 68.48%at 200 mg/kg i.p.However,it did not produce any relief in thermal induced pain at test doses.When challenged against pyrexia evoked by yeast,SLO manifested marked amelioration in hyperthermic mice,dose dependently.Maximum anti-hyperthermic activity(75%)was observed at 200 mg/kg i.p.after 4 h of drug administration.Nevertheless,SLO had no effect on seizures control and mortality caused by pentylenetetrazole.Conclusions:In vivo studies of SLO showed prominent antinociceptive and antipyretic activities with ample safety profile and thus provided pharmacological base for the traditional uses of the plant in various painful conditions and pyrexia.Additional detail studies are required to ascertain its clinical application. | Naveed Muhammad Barkatullah Muhammad Ibrar Haroon Khan Muhammad Saeed Amir Zada Khan Waqar Ahmad Kaleem | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，3： | 2 |
| 2 | Cyclopeptide alkaloids of Ziziphus oxyphylla Edgw as novel inhibitors of α-glucosidase enzyme and protein glycation显示文摘 | M. Iqbal Choudhary Achyut Adhikari Saima Rasheed Bishnu P. Marasini Nusrat Hussain Waqar Ahmad Kaleem Atta-ur-Rahman | 2011 | Phytochemistry Letters2011，，4： | 1 |
| 3 | Molecular simulations probing Kushecarpin A as a new lipoxygenase inhibitor显示文摘 | Muhammad Nisar Waqar Ahmad Kaleem Inamullah Khan Achyut Adhikari Nematullah Khan Muhammad Raza Shah Ihsan Ali Khan Mughal Qayum Samiullah Muhammad Ismail Akhter Aman | 2011 | Fitoterapia2011，，7： | 1 |
| 4 | Monte Carlo Study of CO-NO Catalytic Surface Reaction Including CO-CO Repulsion显示文摘公司 -- 催化表面上的反应都没被 usingLangmuir-Hinshelwood 学习有蒙特卡罗的热机制计算机模拟。在这个模型,当这些分子在表面上被使用化学方法吸附时,椰子排斥的一个新奇概念被介绍,它由于偶极子的形成有试验性的证据。系统被使用没有分离的二条途径调查。嗨第一个案例,总是不在表面上在吸附前分解成 N 和 O。在第二个案例中,不分子地在表面上吸附然后如果一个空缺在它的邻近的邻居是在场的,分裂进 N 和 O。稳定的州的反应窗户(即 CO2 和 N-2 的连续生产) 在表面上仅仅与 N 原子的散开被获得,它在第一个案例中与椰子排斥延长。在第二个案例中,然而,反应窗户独自与椰子排斥被获得。在这种情况中的反应窗户宽度相当大。一阶的阶段转变在两个被消除案例 withCO 公司排斥。 | Waqar Ahmad Musa Kaleem Baloach | 2006 | Chinese Physics Letters2006，23，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员