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| 1 | Plasma miR-216a as a potential marker of pancreatic injury in a rat model of acute pancreatitis显示文摘AIM:To study the potential value and specificity of plasma miR-216a as a marker for pancreatic injury.METHODS:Two rat models were applied in this article:L-arginine-induced acute pancreatitis was used as one model to explore the potential value of plasma miR-216a for detection of pancreatic injury;nonlethal sepsis induced in rats by single puncture cecal ligation and puncture(CLP)was used as the other model to evaluate the specificity of plasma miR-216a compared with twocommonly used markers(amylase and lipase)for acute pancreatitis.Plasmas were sampled from rats at indicated time points and total RNA was isolated.Real-Time Quantitative reverse transcriptase-polymerase chain reaction was used to quantify miR-216a in plasmas.RESULTS:In the acute pancreatitis model,among five time points at which plasmas were sampled,miR-216a concentrations were significantly elevated 24 h after arginine administration and remained significantly increased until 48 h after operation(compared with 0 h time point,P<0.01,Kruskal-Wallis Test).In the CLP model,plasma amylase and lipase,two commonly used biomarkers for acute pancreatitis,were significantly elevated 24 h after operation(compared with 0 h time point,P<0.01 and 0.05 respectively,Pairwise Bonferroni corrected ttests),while miR-216a remained undetectable among four tested time points.CONCLUSION:Our article showed for the first time that plasma miR-216a might serve as a candidate marker of pancreatic injury with novel specificity. | Xiang-Yu Kong,Yi-Qi Du,Lei Li,Xiao-Hua Man,Yan-Fang Gong,Li-Ning Xiao,Yong-Zhi Zheng,Shang-Xin Deng,Jun-Jun Gu,Zhao-Shen Li,Department of Gastroenterology,Changhai Hospital,Second Military Medical University,Shang-hai 200433,China Jian-Qiang Liu,Department of Gastroenterology,Fuzhou General Hospital of Nanjing Military Command,Fuzhou 350025,Fujian Province,China Guo-Kun Wang,Jia-Qi Zhu,Department of Cardiology,Changhai Hospital,Second Military Medical University,Shang-hai 200433,China | 2010 | World Journal of Gastroenterology2010，16，36： | 19 |
| 2 | Relationship between the imaging features and pathologic alteration in hepatoma of rats显示文摘AIM: The imaging features of MRI and DSA, using the modelsof implanted and induced hepatoma, were investigated in rats.METHODS: CBRH3 cancer cells were implanted for differentliver site of rat liver and the diethylnitrosoamine was givenorally to rats in order to induce liver cancer. Both experimentalgroups were detected by magnetic resonance imaging (MRI),digital subtraction angiography (DSA) and morphologic assay.RESULTS: Hypointensity on T1WI and homogenous highsignal intensity on T2WI in MRI, and ring-like abnormal stainon DSA were found in implanted cancer. Induced cancersappeared as homogeneous or heterogeneous hypointensityon T1WI (10 cases), and equal or slight high intensity onT2WI (8 cases), but some as hypointensity on T2WI (2 cases).CONCLUSION: The imaging features of implanted cancerswere similar to that of human liver metastases. Therefore, itcould serve as an experimental model of human liver metastatictumor. The imaging feature of induced cancers, whereas, weresimilar to that of human primary liver cancer. It could be useas an experimental model of human primary liver cancer. | Jia-He Yang Tian-Geng You Nan Li Qi-Jun Qian Ping Wang Zhen-Lin Yan Meng-Chao Wu Eastern Heptobiliary Hospital,225 Changhai Road,Shanghai 200433,China | 2003 | World Journal of Gastroenterology2003，9，1： | 13 |
| 3 | Endoscopic management of biliary complications after orthotopic liver transplantation显示文摘BACKGROUND: Biliary complications are a serious problem in patients after liver transplantation and often require reoperation. This study was conducted to summarize the endoscopic diagnosis and management of biliary complications after orthotopic liver transplantation (OLT). METHODS: From December 2000 to November 2003, twelve endoscopic retrograde cholangiopancreatographies(ERCPs) were performed in 7 patients after OLT at Digestive Endoscopic Center of Changhai Hospital in Shanghai, China. The therapeutic maneuvers included endoscopic sphincterotomy (EST), biliary stent placement, balloon and basket extraction, irrigation, and nasobiliary tube placement. A retrospective study was made to determine the types of biliary tract complications after OLT. The success of ERCP and therapeutic maneuvers was also evaluated. RESULTS: Biliary tract complications including biliary stricture, biliary leak, biliary sludge, and stump leak of the cyst duct were treated respectively by endoscopic sphincterotomy with sludge extraction, stricture dilation or endoscopic retrograde biliary drainage. Two of the 3 patients with proximal common bile duct stricture were successfully treated with ERCP and stent placement. Four patients with anastomotic stricture and/without bile leak were treated successfully by dilation and stent placement or endoscopic nosobiliary drainage. No severe ERCP-related complications occurred. CONCLUSIONS: ERCP is an effective and accurate approach for the diagnosis of biliary tract complications after OLT, and placement of a stent is a safe initial treatment for biliary complications after liver transplantation. | Yun-Sheng Qin, Zhao-Shen Li, Zhen-Xing Sun, Ren-Pei Wu, Na Wang and Yin-Zhen Yao Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou 310003, China Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，1： | 11 |
| 4 | Ultraselective carbon molecular sieve membrane for hydrogen purification显示文摘Hydrogen is a green clean fuel and chemical feedstock. Its separation and purification from hydrogencontaining mixtures is the key step in the production of hydrogen with high purity(>99.99%). In this work, carbon molecular sieve(CMS) membranes with ultrahigh permselectivity for hydrogen purification were fabricated by high-temperature(700–900 ℃) pyrolysis of polymeric precursor of phenolphthaleinbased cardo poly(arylene ether ketone)(PEK-C). The evolution of the microstructural texture and ultramicroporous structure and gas separation performance of the CMS membrane were characterized via TG-MS, FT-IR, XRD, TEM, CO2 sorption analysis and gas permeation measurements. CMS membranes prepared at 700 ℃ exhibited amorphous turbostratic carbon structures and high H2 permeability of 5260 Barrer with H2/CH4, H2/N2 and H2/CO selectivities of 311, 142, 75, respectively. When carbonized at900 ℃, the CMS membrane with ultrahigh H2/CH4 selectivity of 1859 was derived owing to the formation of the dense and ordered carbon structure. CMS membranes with ultrahigh permselectivity exhibit an attractive application prospect in hydrogen purification. | Ruisong Xu Liu He Lin Li Mengjie Hou Yongzhao Wang Bingsen Zhang Changhai Liang Tonghua Wang | 2020 | Journal of Energy Chemistry2020，29，11： | 8 |
| 5 | Research on barrier function and spatio-temporal heterogeneity of vegetation in southern LRGR显示文摘 | HAO Chengyuan DAI Erfu WU Shaohong ZHOU Changhai WANG Hao PAN Tao | 2006 | Chinese Science Bulletin2006，51，B11： | 7 |
| 6 | Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death显示文摘细胞内部的氧化还原作用动态平衡在决定肿瘤房间的敏感到导致药的 apoptosis 起一个关键作用。这里,我们调查了 thioredoxin-1 (TRX1 ) 的角色,氧化还原作用规定的一个关键部件,在砷三氧化物(作为(2 ) O (3 )) 导致的 apoptosis。在 HepG ( 2 )房间的野类型的 TRX1 的在表示上导致了抑制当( 2 ) O ( 3 )导致了细胞色素 c ( cyto c ),释放, caspase 激活和 apoptosis ,并且由 RNAi 的 TRX1 表示的绒毛规定敏化 HepG ( 2 )房间到当( 2 ) O ( 3 )导致了 apoptosis 。有趣地,到重量的单位(32/35 ) 的从 Cys (32/35 ) 的 TRX1 的活跃地点的变化从一个 apoptotic 保护者把这个分子变换成一个 apoptotic 倡导者。以理解这变换的机制,我们从老鼠肝使用了孤立的线粒体并且发现了野类型的 TRX1 能保护的那重组体从 apoptotic 的线粒体变化。相反, TRX1 的变异的形式独自得到了线粒体相关的 apoptotic 变化,包括 mitochondrial 渗透转变毛孔(mPTP ) 洞, mitochondrial 膜潜力的损失,和 cyto 从线粒体的 c 版本。这些 apoptotic 效果被 cyclosporine A (CsA ) 禁止,显示指向到 mPTP 的那变异的 TRX1。到由 2,4-dinitrochlorobenzene (DNCB ) 的氧化形式体内的从它的减少的形式的 TRX1 的改变, TRX reductase 的一个特定的禁止者,也敏化的 HepG (2 ) 房间到当(2 ) O (3 ) 导致了 apoptosis。这些数据建议 TRX1 由任何一个变化在由堵住 cyto c 版本调整 apoptosis,并且在 TRX1 的激活起一个中央作用或活跃地点半胱氨酸的氧化可以敏化肿瘤房间到当(2 ) O (3 ) 导致了 apoptosis。 | Changhai Tian Ping Gao Yanhua Zheng Wen Yue Xiaohui Wang Haijing Jin Quan Chen | 2008 | Cell Research2008，18，4： | 7 |
| 7 | Coupling Relationship Analysis on Households′ Production Behaviors and Their Influencing Factors in Nature Reserves:A Structural Equation Model显示文摘A households′production behavior directly influences the quality of the environment and determines the successful development of nature reserves.Meanwhile,the households′production behaviors are complicated by interrelated factors,such as protection attitudes,resource endowment,and family wealth.This research evaluated households near the Crested Ibis National Nature Reserve in Shaanxi Province,acquiring data from 436 households around Yang County and Ningshan County in the south slope of Qinling Mountains,China.Based on the collected data,we developed a structural equation model to evaluate the coupling relationships among households′ protection attitudes,production behaviors,resource endowment,and family wealth.The results showed that:1) households with great resource endowment had more negative attitudes,probably due to their greater protection costs;2) the households with higher education levels had worse protection attitudes;3) the households with more family wealth were likely to use fewer fertilizers,pesticides,and firewood;4) the households with more resource endowment showed less production and management behaviors;5) the enhancement of households' attitudes improved production behaviors to protection the environment,but the effects were not statistically significant.Our results provide a basis for the government's protection policy making,exploring the effective management measures that are beneficial for both nature reserve management and community development. | WANG Changhai WEN Yali DUAN Wei HAN Feng | 2013 | Chinese Geographical Science2013，23，4： | 6 |
| 8 | Reprogrammed mouse astrocytes retain a“memory”of tissue origin and possess more tendencies for neuronal differentiation than reprogrammed mouse embryonic fibroblasts显示文摘Direct reprogramming of a variety of somatic cells with the transcription factors Oct4(also called Pou5f1),Sox2 with either Klf4 and Myc or Lin28 and Nanog generates the induced pluripotent stem cells(iPSCs)with marker similarity to embryonic stem cells.However,the difference between iPSCs derived from different origins is unclear.In this study,we hypothesized that reprogrammed cells retain a“memory”of their origins and possess additional potential of related tissue differentiation.We reprogrammed primary mouse astrocytes via ectopic retroviral expression of OCT3/4,Sox2,Klf4 and Myc and found the iPSCs from mouse astrocytes expressed stem cell markers and formed teratomas in SCID mice containing derivatives of all three germ layers similar to mouse embryonic stem cells besides semblable morphologies.To test our hypothesis,we compared embryonic bodies(EBs)formation and neuronal differentiation between iPSCs from mouse embryonic fibroblasts(MEFsiPSCs)and iPSCs from mouse astrocytes(mAsiPSCs).We found that mAsiPSCs grew slower and possessed more potential for neuronal differentiation compared to MEFsiPSCs.Our results suggest that mAsiPSCs retain a“memory”of the central nervous system,which confers additional potential upon neuronal differentiation. | Changhai Tian Yongxiang Wang Lijun Sun Kangmu Ma Jialin C.Zheng | 2011 | Protein & Cell2011，2，2： | 6 |
| 9 | Efficient Photoelectrochemical Water Splitting by g-C_3N_4/TiO_2 Nanotube Array Heterostructures显示文摘Well-ordered TiO_2 nanotube arrays(TNTAs)decorated with graphitic carbon nitride(g-C_3N_4) were fabricated by anodic oxidization and calcination process.First, TNTAs were prepared via the anodic oxidation of Ti foil in glycerol solution containing fluorinion and 20%deionized water. Subsequently, g-C_3N_4 film was hydrothermally grown on TNTAs via the hydrogen-bonded cyanuric acid melamine supramolecular complex. The results showed that g-C_3N_4 was successfully decorated on the TNTAs and the g-C_3N_4/TNTAs served as an efficient and stable photoanode for photoelectrochemical water splitting. The facile deposition method enables the fabrication of efficient and low-cost photoanodes for renewable energy applications. | Changhai Liu Fang Wang Jin Zhang Ke Wang Yangyang Qiu Qian Liang Zhidong Chen | 2018 | Nano-Micro Letters2018，10，2： | 6 |
| 10 | Effects of Changtai granules, a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats显示文摘AIM: To study the effects of Changtai granules (CTG), a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. METHODS: Healthy adult Sprague-Dawley (SD) rats of both sexes, weighing 250-300 g, were employed in the present study. The rat colitis models were induced by 2, 4,6-trinitrobenzene sulfonic acid (TNBS) enemas at a concentration of 100 mg/kg in 50% ethanol. The experimental animals were randomly divided into dexamethasone (DX) treatment, CTG treatment, and model control groups, which were intracolicly treated daily with DX (0.2 mg/kg), CTG at doses of 2.9, 5.7 and 11.4 g crude drug/kg, and the equal amount of saline respectively from 6 h following induction of the colitis in rats inflicted with TNBS to the end of study. A normal control group of rats treated without TNBS but saline enema was also included in the study. After 3 wk of treatment, the animals were assessed for colonal inflammatory and ulcerative responses with respect to mortality, frequency of diarrhea, histology and myeloperoxidase activity (MPO).RESULTS: The therapeutic effect of CTG on ulcerative colitis (UC) was better than DX. CTG effectively inhibited the activity of granulocytes, macrophages and monocytes in a dosedependent manner. Also it reduced MPO and formation of inflammation in colonic mucosal tissue. Furthermore, administration of CTG significantly prevented body mass loss and death, and decreased frequency of diarrhea in UC rats, when compared with the model control group rats.CONCLUSION: CTG would prove to be an ideal drug for chronic UC, and is warranted to be studied further. | Yong-Bing Cao,Jun-Dong Zhang,Lan Yan,De-Jun Wang,Xin-Ming Jia,Ping-Hui Gao,Ming-He Cheng,Zheng Xu,Yan Wang,Yuan-Ying Jiang,Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China Ya-Ying Diao,Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China | 2005 | World Journal of Gastroenterology2005，11，23： | 5 |
| 11 | Tectonic Evolution of Southeast Central Asian Orogenic Belt: Evidence from Geochronological Data and Paleontology of the Early Paleozoic Deposits in Inner Mongolia显示文摘In this study, we present detrital zircon U-Pb dating and paleontological data for the newly identified Ayadeng Formation in the northern margin of the North China Block(NCB) and Xibiehe Formation(molasse) in the Bainaimiao arc belt(BAB), which could provide strong evidence indicating the affinity of the BAB and the evolution of the southeast Central Asian orogenic belt(CAOB). Zircon U-Pb data of siltstone samples and paleontological data indicate the Ayadeng Formation dates back to the Early Ordovician. Although its location is near the NCB, its zircon age spectra and paleontology share a closer affinity with those of Tarim and NE Gondwana, as the U-Pb data suggest an age range of 490–2 192 Ma(peak age=629, 788, 965 and 1 935 Ma), and similar gastropod fossils are found in Tarim and NE Gondwana. The U-Pb ages of meta-sandstone samples in the Xuniwusu Formation indicate a shared inheritance with the Ayadeng Formation(before 440 Ma), and the U-Pb ages of sandstone samples in the Xibiehe Formation are concentrated, with age peaks centered at ca. 420 Ma. Fossil corals occur in these two formations, and their age components also indicate a collisional setting. Therefore, it is speculated that the BAB drifted away from Tarim or NE Gondwana during the Ordovician and became attached to northern NCB between 440–420 Ma as an exotic terrane. During the Early Paleozoic, there may have occurred a collision between an arc and a continental block. | Shijie Wang Shichao Li Wenjie Li Zhongyuan Xu Jinfeng Zhang Changhai Li Qiang Shi Yang Liu Wenlong Wang Qingbin Guan | 2020 | Journal of Earth Science2020，31，4： | 4 |
| 12 | Novel passive localization algorithm based on double side matrix-restricted total least squares显示文摘In order to solve the bearings-only passive localization problem in the presence of erroneous observer position, a novel algorithm based on double side matrix-restricted total least squares (DSMRTLS) is proposed. First, the aforementioned passive localization problem is transferred to the DSMRTLS problem by deriving a multiplicative structure for both the observation matrix and the observation vector. Second, the corresponding optimization problem of the DSMRTLS problem without constraint is derived, which can be approximated as the generalized Rayleigh quotient minimization problem. Then, the localization solution which is globally optimal and asymptotically unbiased can be got by generalized eigenvalue decomposition. Simulation results verify the rationality of the approximation and the good performance of the proposed algorithm compared with several typical algorithms. | Xu Zheng Qu Changwen Wang Changhai | 2013 | Chinese Journal of Aeronautics2013，26，4： | 4 |
| 13 | Detrital Zircon U–Pb Geochronology and Provenance of Bayan Obo Group, Northern Margin of North China Craton: New Implications for the Position of NCC in Rodinia显示文摘The paleoposition of North China Craton in Rodinia has long been in controversial. This paper mainly focuses on the U-Pb geochronological studies of detrital zircons obtained from Bayan Obo Group exposed in the Shangdu area, Inner Mongolia, aiming to provide more information for interprating this problem. Based on the acquired data, this paper comes to the following conclusions. Firstly, the depositional age of Bayan Obo Group might be from Meso- to Neoproterozoic according to the zircons U-Pb dating results. The lower succession of this group, namely Dulahala and Jianshan formations deposited between 1800 and 1650 Ma. The Halahuogete and Bilute formations deposited between 1500 and 1350 Ma. For Baiyinbaolage and Hujiertu formations, their depositional age was 1250-900 Ma. Secondly, for the provenance of Bayan Obo Group, this paper believes detrital zircons with age of 2.51-2.71 Ga and 2.00-2.48 Ga were from Guyang, Xi Ulanbulang and Zhuozi area;the Khondalite Belt provided detrital zircons with age of 1.95-1.80 Ga;zircons with age of 1.60-1.75 Ga might come from granitic rocks in Miyun Area. The magmatism after 1.60 Ga was rarely recorded in the NCC, therefore those zircons with ages younger than 1.60 Ga might come from outside of NCC. The magmatism with the same age existed in Baltic, Amazonia and Laurentia. Based on previous paleomagnetic researches, this paper proposes that NCC might receive detritus from Baltic during 1560-1350 Ma and had affinity with Laurentia and Amazonia at ~0.9 Ga in Rodinia. Baltic, Amazonia and Laurentia might be potential provenances for non-NCC detritus in Bayan Obo Group. | LI Changhai LIU Zhenghong XU Zhongyuan DONG Xiaojie LI Pengchuan SHI Qiang WANG Shijie | 2019 | Acta Geologica Sinica(English Edition)2019，93，5： | 4 |
| 14 | Highly stable and selective Ru/NiFe2O4 catalysts for transfer hydrogenation of biomass-derived furfural to 2-methylfuran显示文摘Spinel ferrites NiFe_2O_4 supported Ru catalysts have been prepared via a simple sol–gel route and applied for converting biomass-derived furfural to 2-methylfuran. The as-prepared catalysts were characterized by thermogravimetric analysis(TG), N_2 adsorption–desorption, X-ray diffraction(XRD), scanning electronic microscopy(SEM), and X-ray photoelectron spectroscopy(XPS). Results showed that the catalysts had well-dispersed Ru active sites and large surface area for calcination temperature ranging from 300 to 500 ℃. The conversion of biomass-derived furfural into 2-methylfuran was conducted over Ru/NiFe_2O_4 through catalytic transfer hydrogenation in liquid-phase with 2-propanol as the hydrogen source. A significantly enhanced activity and increased 2-methylfuran yield have been achieved in this study. Under mild conditions(180 ℃ and 2.1 MPa N_2), the conversion of furfural exceeds 97% and 2-methylfuran yield was up to 83% over the catalyst containing 8 wt% Ru. After five repeated uses, the catalytic activity and the corresponding product yield remained almost unchanged. The excellent catalytic activity and recycling performance provide a broad prospects for various practical applications. | Baowei Wang Chuang Li Bo He Ji Qi Changhai Liang | 2017 | Journal of Energy Chemistry2017，26，4： | 4 |
| 15 | Multi-dimensional overall regulatory modes and threshold values for water cycle of the Haihe River Basin显示文摘In this study, a multi-dimensional critical regulatory criteria and decision-making mechanism based on the scientific cognition of multi-dimensional attributes and characteristics of the water cycle was proposed. This system was functioned by deeply discriminating the nature-society binary characteristics of the five-dimensional characteristics of the water cycle system of the Haihe River Basin (water resources, economy, society, ecology, and environment) under the influence of high-intensity human activities and hydrological changes and by analyzing the organic interactive relationships between the five dimensions and their overall effect on the water cycle. A GDP calculation model was constructed in this study by adjusting the water environment for water resources, after which five-dimensional normalization objective functions were established for multi-objective analysis to carry out trade-off analysis of multi-dimensional regulatory indexes. In addition, synergetic theory, entropy theory and dissipation structure theory were introduced to construct an evaluation model for multi-dimensional regulatory schemes. A water cycle multi-dimensional critical overall regulatory model system was also established. This system consisted of a multi-objective macroeconomic model (DAMOS), water resource allocation model based on rules (ROWAS), evaluation model for WEDP (EMW) and multi-dimensional regulatory scheme evaluation model (SEAMUR) as the main body. To address the national demands faced by the Haihe River Basin as a result of combinatorial schemes for different hydrological series and water amounts diverted by the south-to-north water diversion project, this study adopted a hierarchy progression method to set up the technologies, investigated multi-dimensional overall regulatory methods, proposed an overall regulation threshold value for the water cycle of the Haihe River Basin, and recommended corresponding five-dimensional regulatory schemes. | GAN Hong WANG Lin CAO YinBai YOU JinJun GAN ZhiGuo QIN ChangHai HE Shan XU Kai | 2013 | Chinese Science Bulletin2013，58，27： | 4 |
| 16 | A new charging scheme in an emergency department observation unit under Beijing's basic medical insurance显示文摘 | He Xinhua Gao Li Teng Fei Liu Changhai Wang Shuo Wu Caijun Xu Li Li Chunsheng | 2014 | Chinese Medical Journal2014，，18： | 3 |
| 17 | A sophisticated simulation for the fracture behavior of concrete material using XFEM显示文摘The development of a powerful numerical model to simulate the fracture behavior of concrete material has long been one of the dominant research areas in earthquake engineering.A reliable model should be able to adequately represent the discontinuous characteristics of cracks and simulate various failure behaviors under complicated loading conditions.In this paper,a numerical formulation,which incorporates a sophisticated rigid-plastic interface constitutive model coupling cohesion softening,contact,friction and shear dilatation into the XFEM,is proposed to describe various crack behaviors of concrete material.An effective numerical integration scheme for accurately assembling the contribution to the weak form on both sides of the discontinuity is introduced.The effectiveness of the proposed method has been assessed by simulating several well-known experimental tests.It is concluded that the numerical method can successfully capture the crack paths and accurately predict the fracture behavior of concrete structures.The influence of mode-Ⅱ parameters on the mixed-mode fracture behavior is further investigated to better determine these parameters. | Zhai Changhai Wang Xiaomin Kong Jingchang Li Shuang Xie Lili | 2017 | Earthquake Engineering and Engineering Vibration2017，16，4： | 3 |
| 18 | Preliminary experimental results by the prototype of Sanya Incoherent Scatter Radar显示文摘In the past decades,the Incoherent Scatter Radar(ISR)has been demonstrated to be one of the most powerful instruments for ionosphere monitoring.The Institute of Geology and Geophysics at the Chinese Academy of Sciences was founded to build a state-ofthe-art phased-array ISR at Sanya(18.3°N,109.6°E),a low-latitude station on Hainan Island,named the Sanya ISR(SYISR).As a first step,a prototype radar system consisting of eight subarrays(SYISR-8)was built to reduce the technical risk of producing the entire large array.In this work,we have summarized the preliminary experimental results based on the SYISR-8.The amplitude and phase among 256 channels were first calibrated through an embedded internal monitoring network.The mean oscillation of the amplitude and phase after calibration were about 1 dB and 5°,respectively,which met the basic requirements.The beam directivity was confirmed by crossing screen of the International Space Station.The SYISR-8 was further used to detect the tropospheric wind profile and meteors.The derived winds were evaluated by comparison with independent radiosonde and balloon-based GPS measurements.The SYISR-8 was able to observe several typical meteor echoes,such as the meteor head echo,range-spread trail echo,and specular trail echo.These results confirmed the validity and reliability of the SYISR-8 system,thereby reducing the technical risk of producing the entire large array of the SYISR to some extent. | XinAn Yue WeiXing Wan Han Xiao LingQi Zeng ChangHai Ke BaiQi Ning Feng Ding BiQiang Zhao Lin Jin Chen Li MingYuan Li JunYi Wang HongLian Hao Ning Zhang | 2020 | Earth and Planetary Physics2020，4，6： | 3 |
| 19 | 腹主动脉瘤发病机理的实验研究 Ⅱ.基质金属蛋白酶-9在大鼠腹主动脉瘤模型中的动态表达显示文摘目的 :检测MMP 9在大鼠正常动脉及动脉瘤模型组织中的动态表达 ,以探讨其在腹主动脉瘤发病机制中的作用。方法 :Wistar大鼠 5 4只 ,随机均分为 1组正常对照组、4组灌注对照组和 4组实验组。实验组腹主动脉灌注弹力蛋白酶 (2 5U ml) 2ml,灌注对照组灌注生理盐水 2ml,分别于术前、术后即刻、2d、7d、14d测量腹主动脉直径 ,并采用免疫组织化学和分子原位杂交技术动态检测腹主动脉组织中MMP 9的表达。结果 :正常及灌注对照组腹主动脉组织中均未发现MMP 9,而实验组弹力蛋白酶灌注后2~ 14dMMP 9均有不同程度升高 ,第 7d达到高峰 ,第 14d有所回落。结论 :MMP 9分泌的增加可能与炎症反应有关 ,且为腹主动脉瘤形成中不可或缺的一步。 | WANG Hao,JING Zai ping,Institute of Vascular Surgery of PLA,Department of Vascular Surgery,Changhai Hospital,The Second Military Medical University(Shanghai 200433,China) | 2002 | 中国现代普通外科进展2002，5，4： | 3 |
| 20 | Exergy Analysis of Electric Vehicle Heat Pump Air Conditioning System with Battery Thermal Management System显示文摘The exergy analysis of an electric vehicle heat pump air conditioning system(HPACS) with battery thermal management system was carried out by studying the exergy loss of each component. The results indicate that the compressor is the main source of system exergy loss in all operation conditions. The exergy loss distribution of HPACS is almost the same when the battery thermal management system integrated into the HPACS in cabin and battery mixed cooling mode and the system exergy loss was linearly related to the compressor speed in cooling modes. The performance of the HPACS is better than that of the positive temperature coefficient(PTC) heater in cabin heating mode. The degree of exergy efficiency improvement of the alternative mode was discussed at all operation conditions in cabin heating mode. The results indicate that the optimization effect using the electric vehicle HPACS to replace the PTC heater is obvious at lower compressor speed, surrounding temperature and internal condenser air flow rate. | ZHANG Kexin LI Ming YANG Changhai SHAO Zhiyuan WANG Lihong | 2020 | Journal of Thermal Science2020，29，2： | 3 |
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