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| 1 | Low-grade gliomas:do changes in rCBV measurements at longitudinal perfusion-weighted MR imaging predict malignant transformation?显示文摘Radiology. 2008 Apr;247(1):170-8.PURPOSE: To prospectively perform longitudinal magnetic resonance (MR) perfusion imaging of conservatively treated low-gradegliomas to determine whether relative cerebral blood volume (rCBV) changes precede malignant transformation as defined | Danchaivijitr N Waldman AD Tozer DJ Benton CE Brasil Caseiras G Tofts PS Rees JH J?ger HR | 2008 | 中国神经肿瘤杂志2008，6，2： | 7 |
| 2 | Guanylyl cyclase C signaling axis and colon cancer prevention显示文摘Colorectal cancer(CRC) is a major cause of cancerrelated mortality and morbidity worldwide. While improved treatments have enhanced overall patient outcome, disease burden encompassing quality of life, cost of care, and patient survival has seen little benefit. Consequently, additional advances in CRC treatments remain important, with an emphasis on preventative measures. Guanylyl cyclase C(GUCY2C), a transmembrane receptor expressed on intestinal epithelial cells, plays an important role in orchestrating intestinal homeostatic mechanisms. These effects are mediated by the endogenous hormones guanylin(GUCA2A) and uroguanylin(GUCA2B), which bind and activate GUCY2 C to regulate proliferation, metabolism and barrier function in intestine. Recent studies have demonstrated a link between GUCY2 C silencing and intestinal dysfunction, including tumorigenesis. Indeed, GUCY2 C silencing by the near universal loss of its paracrine hormone ligands increases colon cancer susceptibility in animals and humans. GUCY2C's role as a tumor suppressor has opened the door to a new paradigm for CRC prevention by hormone replacement therapy using synthetic hormone analogs, such as the FDA-approved oral GUCY2 C ligand linaclotide(Linzess^(TM)). Here we review the known contributions of the GUCY2 C signaling axis to CRC, and relate them to a novel clinical strategy targeting tumor chemoprevention. | Amanda M Pattison Dante J Merlino Erik S Blomain Scott A Waldman | 2016 | World Journal of Gastroenterology2016，22，36： | 2 |
| 3 | Suppression of distortion product emissions(DPOAE) near 2f1 - f2 removes DP-gram fine structure-Evidence for a secondary generator 显示文摘 | Heitmann J Waldman B Schnitzler H U | 1998 | J Acoust Soc Am1998，103，： | 1 |
| 4 | Transformational leadership and the falling dominoes effect显示文摘 | BASS B M WALDMAN D A AVOLIO B J | 1987 | Group&Organization Management1987，12，1： | 1 |
| 5 | Chemical composition of acid fog显示文摘 | Waldman J M Munger J W Jacob D J | 1982 | Science1982，218，： | 1 |
| 6 | Wintertime measurements of aerosol acidity and trace elements in Wuhan, a City in Central China显示文摘 | Lioy P J Zelenka M | 1991 | Atmosphere Environment1991，25，1： | 1 |
| 7 | Genomic alterations in tubular breast carcinomas显示文摘 | Waldman FM Hwang ES Etzell J | 2001 | Hum Pathol2001，32，2： | 1 |
| 8 | Scar remodeling and transmural deformation after infarction in the pig显示文摘 | Holmes J W Yamashita H Waldman L K | 1994 | Circula- tion1994，90，1： | 1 |
| 9 | Does leadership matter? CEO leadership attributes and profitability under conditions of perceived environmental uncertainty显示文摘 | RAMIREZ G G HOUSE R J PURANAM P | 2001 | Academy of Management Journal2001，44，1： | 1 |
| 10 | Infected total knee arthroplasty treated by arthroscopic irrigation and de- bridement 显示文摘 | Waldman B J Hostin E Mont M A | 2000 | J Arthroplasty2000，15，4： | 1 |
| 11 | Thermal properties of high density polyethylene composites with natural fibres:Coupling agent effect显示文摘 | Arau'jo J R Waldman W R De Paoli M A | 2008 | Polymer Degradation and Stability2008，93，10： | 1 |
| 12 | Stock structure and homing fidelity in Gulf of Mexico sturgeon base on restriction fragment length polymorphism and sequence analysis of mitochondrial DNA显示文摘 | Stabile J Waldman J R Paranka F | 1995 | Genetics1995，144，： | 1 |
| 13 | Noise Trader Risk in Finance Market显示文摘 | De Long J Bradford Andrei Shleifer Lawrence H Summers and Robert Waldman | 1990 | Journal of Political Economy1990，，98： | 1 |
| 14 | Blunt chest trauma resulting in both atrial and ventricular septal defects显示文摘 | Yahaira Ortiz Adam J Waldman | 2015 | Echocardiography2015，32，3： | 1 |
| 15 | CEO charismatic leadership: Level-of-management and level-of-analysis effects 显示文摘 | Waldman D A Yammarino F J | 1999 | Academy of Management Review1999，24，2： | 1 |
| 16 | Terahertz inverse synthetic aperture radar (ISAR) imaging with a quantum cascade laser transmitter显示文摘 | Andriy A D Thomas M G Waldman J | 2010 | Optics Express2010，18，16： | 1 |
| 17 | Expanding the HCCl operation with the charge stratification 显示文摘 | AROONSRISOPON T WERNER P WALDMAN J et al | 2004 | SAE Paper2004，01，： | 1 |
| 18 | Does leadership matter? CEO leadership attributes and profitability under conditions of perceived environmental uncertainty显示文摘 | Waldman D A Ramirez G G House R J | 2001 | Academy of Management Journal2001，44，1： | 1 |
| 19 | The production and analysis of microcellular thermoplastic foams显示文摘 | MARTINI J E WALDMAN F A SUH N P | 1982 | SPE ANTEC Tech Papers1982，，： | 1 |
| 20 | Inhibition of angiogenesis-related endothelial activity by the experimental immunosuppressive agent leflunomide显示文摘 | Waldman W J Bickerstaff A Gordillo G | 2001 | Transplantation2001，72，9： | 1 |
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