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52篇 您的检索式:作者名="WHITNEY CG"
    题名 作者 年代 出处 被引量
1肺炎链球菌耐药性和血清型分布及隐匿性耐药克隆株的研究显示文摘目的 了解儿童肺炎链球菌携带者耐药菌株的流行情况 ,比较携带者菌株血清型与肺炎链球菌结合疫苗血清型的符合率 ,寻找单个患儿同时携带敏感和耐药菌株的可能性。方法 (1)对1997年 11月~ 12月在北京儿童医院普通门诊登记的 3个月~ 5岁儿童进行问卷调查 ;(2 )采集鼻咽拭子和尿标本 ,培养、分离和鉴定肺炎链球菌 ,并测定尿标本中的抗生素活性 ;(3)根据NCCLS方法使用微量稀释法测定肺炎链球菌对青霉素、头孢呋新、头孢噻肟、复方新诺明、红霉素和氯霉素的敏感性 ;(4 )从最初发现的青霉素、红霉素敏感株中寻找“隐匿性耐药克隆株”。结果 (1) 5 0 2例受试儿童中 ,分离出 190株肺炎链球菌 ,携带率为 37.8% (190 / 5 0 2 ) ,对青霉素的敏感率为 91.1% ;(2 )只有33 .9%的菌株血清型与建议使用的肺炎链球菌结合疫苗血清型相符 ;(3) 4 2例含青霉素和红霉素敏感菌株鼻咽拭子中发现 6株 (14% )“隐匿性耐药克隆株”。结论 在携带者中 ,肺炎链球菌对 β 内酰胺类耐药还不常见 ,但对红霉素和复方新诺明耐药却非常严重 ;建议使用的结合疫苗血清型不能覆盖大部分携带菌株 ;耐药菌株的小部分隐匿在敏感菌株中 。俞桑洁 王槿芳 李洁 李艳 王雪莲 Whitney CG Levine OS Dowell SF 杨永弘 2000中华儿科杂志2000,38,7:40
2Decline in invasive pneumococcal disease after the introduction of protein-polysaccha- ride conjugate vaccine显示文摘WHITNEY CG FARLEY MM HADLERJ 2003N EnglJ Med2003,348,18:1
3Call to action on world pneumoniaday显示文摘Hajjeh R Whitney CG 2012Emerg Infect Dis2012,18,11:1
4Decline in invasive pneumoeoccal disease after the introduction of protein-polysaccharide conjugate vaccine显示文摘Whitney CG Farley MM Hadler J 2003N Engl J Med2003,348,18:1
5Bacterial meningitis in the United States, 1998-2007显示文摘Thigpen MC Whitney CG Messonnier NE 2011N Engl J Med2011,364,21:1
6Decline in invasivepneumococcal disease after the introduction of protein-polysaccha-ride conjugate vaccine 显示文摘Whitney CG Farley MM Hadler J 2003N Engl J Med2003,348,18:1
7Bacterial meningitis in the United States, 1998 2007显示文摘Thigpen MC Whitney CG Messonnier NE 2011N Engl J Med2011,364,21:1
8Decline in invasive pneumococcal disease after the introduction of proteinpolysaccharide conjugate vaccine 显示文摘Whitney CG Farley MM Hadler J 2003N Engl J Med2003,348,18:1
9Incidence of macrolide resistance in Streptococcus pneumoniae after introduction of the pneumococcal conjugate vaccine: population- based assessment显示文摘Stephens DS Zughaier SM Whitney CG 2005Lancet2005,365,9462:1
10Decline in invasive pneumococ-cal disease alter the introduction of prolein-polysaccharide conjugate vac-cine显示文摘Whitney CG Farley MM Hadler J 2003N Engl J Med2003,348,18:1
11Bacterial meningitis in the United States,1998-2007显示文摘Thigpen MC Whitney CG Messonnier NE 0,,21:1
12Rethinking rec- ommendations for use of pneumococcal vaccines in adults 显示文摘WHITNEY CG SCHAFFNER W BUTLER JC 2001Clin Infect Dis2001,33,5:1
13Lower respiratory tract infections: prevention using vaccines显示文摘WHITNEY CG HARPER SA 2004Infect Dis Clin North Am2004,18,4:1
14Community outbreak of Mycoplasma pneumoniae infection:school-based cluster of neurologic disease associated with household transmission of respiratory illness显示文摘Walter ND Grant GB Bandy U Alexander NE Winchell JM Jordan HT Sejvar JJ Hicks LA Gifford DR Alexander NT Thurman KA Schwartz SB Dennehy PH Khetsuriani N Fields BS Dillon MT Erdman DD Whitney CG Moore MR 2008J Infect Dis2008,198,8:1
15Bacterial meningitis in the United States,1998-2007显示文摘Thigpen MC Whitney CG Messonnier NE 2011N Engl J Med2011,364,21:1
16Cost-Effectiveness of Pneumococcal Conjugate Vaccine: Evidence from the first five years of use in the United States incorporating herd effects 显示文摘GT Ray CG Whitney BH Fireman 2006Pediatric Infectious Disease Journal2006,25,06:1
17Assessment of the safety of a third dose of pneumocoecal polysaccharide vac- cine in the Vaccine Safety Datalink population 显示文摘Jackson LA Nelson JC Whitney CG 2006Vaccine2006,24,2:1
18Risk of bacterial meningitis in children with cochlear implants显示文摘Reefhuls J Honein MA Whitney CG 2003N Engl J Med2003,349,:1
19Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States 显示文摘Whitney CG Farley MM Hadler J 2000N Engl J Med2000,343,26:1
20Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin 显示文摘SCHRAG SJ MCGEE L WHITNEY CG 2004Antimicrob Agents Chemother2004,48,8:1
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