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| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | A line balancing heuristic case study for existing automated surface mount assembly line setups显示文摘 | Watkins R E Cochran J K | 1995 | Computers & Industrial Engineering1995，29，1： | 1 |
| 3 | Where is my bus? impact of mobile real time information on the perceived and actual waite time of transit riders 显示文摘 | Watkins K E Ferris B Borning A | 2011 | Transportation Research Part A2011，45，： | 1 |
| 4 | Skeletal Muscle Lipid Content and Oxidative Enzyme Activity in Relation to Muscle Fiber Type in Type 2 Diabetes and Obesity显示文摘 | HE J WATKINS S DAVID E K | 2001 | Diabetes2001，50，4： | 1 |
| 5 | Demonstrating the value of an organization's learning culture:The dimensions of the learning organization question-naire显示文摘 | Watkins K E Marsick V J | 2003 | Advances in Developing Human Resources2003，5，2： | 1 |
| 6 | Demonstrating the value of an organization's learning culture: The Dimensions of Learning Organizations Questionnaire显示文摘 | Marsick V J Watkins K E | 2003 | Adv Dev Hum Resour2003，5，2： | 1 |
| 7 | The construct of the learning organization: Dimensions, measurement, and validation 显示文摘 | Yang B Watkins K E Marsick V J | 2004 | Human Resource Development Quarterly2004，15，1： | 1 |
| 8 | Solution of three-dimensional natural convec- tion about a vertical square rod in a cylindrical en closure显示文摘 | GLAKPE E K WATKINS C B Jr KURIEN B | 1987 | Int J Numer Meth Fluids1987，7，2： | 1 |
| 9 | Smart fiber-reinforced polymer rods featuring improved ductility and health monitoring capabilities显示文摘 | Belarbi A Watkins Steve E Chandrashekhara K | 2001 | Smart Material Structure2001，10，3： | 1 |
| 10 | Demonstrating the value of an organization's learning culture: the dimensions of the learning organization questionnaire 显示文摘 | MARSICK V J WATKINS K E | 2003 | Advances in Developing Human Resources2003，5，2： | 1 |
| 11 | How adaptiveand maladaptive perfectionism relate to positive and nega-tive psychological functioning:testing a stress-mediationmodel in black and white female college students显示文摘 | Chang E C Watkins AF Banks H K | 2004 | Jour-nal of Counseling Psychology2004，51，1： | 1 |
| 12 | Informal and incidental learning 显示文摘 | Marsick V J & Watkins K E | 2001 | New Directions for Adult and ContinuingEducation2001，，89： | 1 |
| 13 | Interannual variability of the South Georgia marine ecosystem: biological and physical sources of variation in theabundance of krill 显示文摘 | Murphy E J Watkins J L Reid K | 1998 | Fish Oceanogr1998，7，34： | 1 |
| 14 | The Construct of Learn- ing Organization: Dimensions, Measurement, and Validation 显示文摘 | Yang B Y Watkins K E Marsick V J | 2004 | Human Resource Development Quarterly2004，15，1： | 1 |
| 15 | Making learning count! diagnosing the learning culture in organization显示文摘 | WATKINS K E MARSICK V J | 2003 | Advances in Developing Human Resources2003，5，2： | 1 |
| 16 | Behavioral analysis of an inherited speech and language disorder: comparison with acquired aphasis显示文摘 | Watkins K E Dronkers N F Vargha K F | 2002 | Brain2002，125，3： | 1 |
| 17 | Demonstrating the value of an organization's learning culture:The Dimensions of Learning Organizations Questionnaire显示文摘 | Marsick V J Watkins K E | 2003 | Advances in Developing Human Resources2003，，5： | 1 |
| 18 | Interannual variability of the South Georgia marine ecosystem, biological and physical sources of variation in the abundance of krill 显示文摘 | MURPHY E J WATKINS J L REID K | 1998 | Fisheries Oceanography1998，7，3： | 1 |
| 19 | Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo显示文摘 | Moldt B Rakasz E G Schultz N Chan-Hui P Y Swiderek K Weisgrau K L Piaskowski S M Bergman Z Watkins D I Poignard P Burton D R | 2012 | Proc Natl Acad Sci USA2012，109，18： | 1 |
| 20 | The Construct of the Learning Organization: Dimensions, Measurement, and Validation 显示文摘 | Yang B Y Watkins K E Marsick V J | 2004 | Human Resource Development Quarterly2004，15，1： | 1 |
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