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	题名	作者	年代	出处	被引量
1	Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study显示文摘BACKGROUND Lateral internal sphincterotomy is still the approach of choice for the treatment of chronic anal fissure(CAF)with internal anal sphincter(IAS)hypertonia,but it is burdened by high-risk postoperative faecal incontinence(FI).Sphincter saving procedures have recently been reconsidered as treatments to overcome this risk.The most employed procedure is fissurectomy with anoplasty,eventually associated with pharmacological sphincterotomy.AIM To evaluate whether fissurectomy and anoplasty with botulinum toxin injection improves the results of fissurectomy and anoplasty alone.METHODS We conducted a case-control study involving 30 male patients affected by CAF with hypertonic IAS who underwent fissurectomy and anoplasty with V-Y cutaneous flap advancement.The patients were divided into two groups:Those in group I underwent surgery alone,and those in group II underwent surgery and a botulinum toxin injection directly into the IAS.They were followed up for at least 2 years.The goals were to achieve complete healing of the patient and to assess the FI and recurrence rate along with manometry parameters.RESULTS The intensity and duration of post-defecatory pain decreased significantly in both groups of patients starting with the first defecation,and this reduction was higher in group II.Forty days after surgery,we achieved complete wound healing in all the patients in group II but only in 80%of the patients in group I(P<0.032).We recorded 2 cases of recurrence,one in each group,and both healed with conservative therapy.We recorded one temporary and low-grade postoperative case of“de novo”FI.Manometry parameters reverted to the normal range earlier for group II patients.CONCLUSION The injection of botulinum toxin A in association with fissurectomy and anoplasty with a V-Y advancement flap improves the results of surgery alone in patients affected by CAF with IAS hypertonia.	Beatrice D'Orazio Girolamo Geraci Fausto Famà Gloria Terranova Gaetano Di Vita	2021	World Journal of Clinical Cases2021，9，32：	2
2	Hypercoaguiable state in patients with advanced gastrointestinal cancer: evidence for an acquired resistance to activated protein C显示文摘	De lucia D De Vita F Orditura M	1997	Tumor1997，83，6：	1
3	Short-term effect of acupuncture on intraocular pressure in healthy subjects显示文摘	Meira-Freitas D Cariello A J Vita R C	2010	Acupunct Med2010，28，1：	1
4	Design criteria for the RF sec- tion of UHF and microwave passive RFID transponders 显示文摘	G D Vita G Iannaccone	2005	IEEE Trans Microware Theory Tech2005，33，9：	1
5	Superiorty of ProMACE-cytaBOM over ProMACE-MOPP in the treatment of advanced difuse aggressive lymphoma:results of a prospective randomized trail显示文摘	Longo D L De Vita V T Duffey P L	1991	J Clin Oncol1991，9，：	1
6	The recurrent goiter:prevention and management显示文摘	Cappel ani A Di Vita M Zanghì A Lo Menzo E Caval aro A Alfano G Giuffrida D		0，，04：	1
7	Serum Interleukin levels as a prognostic factor in advanced Non-small cell lung cancer patients显示文摘	Vita F D Orditura M Galizia G	2000	Chest2000，117，2：	1
8	Asset specifity's impact on outsourcing relationship performance : a disaggregated analysis by buyer-supplier asset specificity dimensions显示文摘	Vita G D Tekaya A Wang L C	2010	Journal of Businerss Research2010，63，3：	1
9	Intact sytolic left ventricular function in clinical congestive heart failure 显示文摘	Soufer R Wohigelernter D Vita NA	1985	Am J Cardiol1985，55，：	1
10	Effect of medical and surgical weight loss on endothelial vasomotor function in obese patients显示文摘	Gokce N Vita JA Mcdonnell M et d	2005	Am J Cardiol2005，95，2：	1
11	Gene-gene interactions in the folate metabolic pathway influence the risk for acute lymphoblastic leukemia in children显示文摘	Petra BG Janez J Vita D	2007	Leuk Lympho-ma2007，48，4：	1
12	Successful combined therapy for refractory chronic urticaria in a 10-year-old boy显示文摘	VITA D PASSALACQUA G CAMINITI L	2004	Allergy2004，59，9：	1
13	Acute inflammatory response after inguinal and incisional hernia repair with implantation of polypropylene mesh of different size显示文摘	Gaetano Vita Pietro D’Agostino Rosalia Patti Matteo Arcara Giuseppe Caruso Valentina Davì Enrico Cillari	2005	Langenbeck’s Archives of Surgery2005，，4：	1
14	Design criteria for the RF section of UHF and microwave passive RFID transponders 显示文摘	VITA G' D IANNACCONE G	2005	IEEE Transactions on Microwave Theory and Techniques2005，，53：	1
15	Involvement of oleuropein in (some) digestive metabolic pathways 显示文摘	Egidi D Vita A	2004	Food Chem2004，88，1：	1
16	Intact systolic left ventricular function in clinical congestive heart failure 显示文摘	Soufer R Wohlgelernter D Vita NA	1985	Am J Cardiol1985，55，：	1
17	Cytokines and growth factors in wound drainage fluid from patients undergoing incisional hernia repair显示文摘	Di Vita G Patti R D'Agostino P	2006	Wound Repair Regen2006，14，3：	1
18	No-tillage and conventional tillage effects on durum wheat yield, grain quality and soil moisture content in southern Italy显示文摘	Vita D P Paolo E D Fecondo G	2007	Soil and Tillaee Research2007，92，12：	1
19	Clinical impact of thrombectomy in acute ST-elevation myo- cardial infarction: an individual patient-data pooled a- nalysis of 11 trials显示文摘	BURZOTTA F VITA M D GUY L	2009	Eur Heart J2009，30，：	1
20	A time-domain raw signal simulator for interferometrie SAR显示文摘	Mori A Vita F D	2004	IEEE Transactions on Geoseienee and Remote Sensing2004，42，9：	1

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