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| 1 | Clinical implications of diabetes in chronic liver disease:Diagnosis,outcomes and management,current and future perspectives显示文摘Diabetes mellitus(DM)is common in liver cirrhosis(LC).The pathophysiological association is bidirectional.DM is a risk factor of LC and LC is a diabetogenic condition.In the recent years,research on different aspects of the association DM and LC has been intensified.Nevertheless,it has been insufficient and still exist many gaps.The aims of this review are:(1)To discuss the latest understandings of the association of DM and LC in order to identify the strategies of early diagnosis;(2)To evaluate the impact of DM on outcomes of LC patients;and(3)To select the most adequate management benefiting the two conditions.Literature searches were conducted using Pub Med,Ovid and Scopus engines for DM and LC,diagnosis,outcomes and management.The authors also provided insight from their own published experience.Based on the published studies,two types of DM associated with LC have emerged:Type 2 DM(T2 DM)and hepatogenous diabetes(HD).High-quality evidences have determined that T2 DM or HD significantly increase complications and death pre and post-liver transplantation.HD has been poorly studied and has not been recognized as a complication of LC.The management of DM in LC patients continues to be difficult and should be based on drug pharmacokinetics and the degree of liver failure.In conclusion,the clinical impact of DM in outcomes of LC patients has been the most studied item recently.Nevertheless many gaps still exist particularly in the management.These most important gaps were highlighted in order to propose future lines for research. | Diego García-Compeán Emanuela Orsi Ramesh Kumar Felix Gundling Tsutomu Nishida Jesús Zacarías Villarreal-Pérez Ángel N Del Cueto-Aguilera JoséA González-González Giuseppe Pugliese | 2022 | World Journal of Gastroenterology2022，28，8： | 4 |
| 2 | Multiphasic contrast-enhanced multidetector-row CT of liver:Contrast-enhancement theory and practical scan protocol with a combination of fixed injection duration and patients' body-weight-tailored dose of contrast material显示文摘 | Tomoaki I Sukru ME Tsutomu A | | 0，，02： | 1 |
| 3 | The life cycle of Streptopharagus pigmentatus (Nematoda, Spiruroidea) from the Japanese monkey显示文摘 | Masaaki M Jun A Tsutomu K | 1978 | Bull Natl Sci Mus Ser A Zoology1978，4，1： | 1 |
| 4 | Synthesis and characterization of novel benzoxazine monomers containing allyl groups and their high performance thermosets 显示文摘 | Tarek A Tsutomu T | 2003 | Macromolecules2003，36，： | 1 |
| 5 | Visualization study of three dimensional flows in a turbine cascade endwall region显示文摘 | Tatsuo K I Shuji S Tsutomu A | 1990 | JSME International Journal Series B1990，33，2： | 1 |
| 6 | Novel organic-inorganic hybrids prepared from polybenzoxazine and titania using sol-gel process显示文摘 | Tarek A Hajime T Tsutomu T | 2004 | Polymer2004，45，： | 1 |
| 7 | Preparation, characterization, and polymerization of maleimidobenzoxazine monomers as a novel class of thermosetting resins显示文摘 | Tarek A Tsutomu T | 2006 | J of Polymer Science: Part A: Polymer Chemistry2006，44，： | 1 |
| 8 | Some physical properties of wood and cellulose irradiated with Gamma rays显示文摘 | Tsutomu A Norimoto Misato Yamada T | 1977 | Wood research1977，62，： | 1 |
| 9 | Unit-axial stress-strain relationship of concrete confined by various shaped steel tubes 显示文摘 | Susantha K A S Ge Hanbin Usami Tsutomu | 2001 | Engineering Structures2001，23，： | 1 |
| 10 | Jitter analysis of high-speed sampling systems显示文摘 | Mitsuru S Yukio A Tsutomu W | 1990 | IEEE Journal of Solid-state Circuits1990，25，1： | 1 |
| 11 | Serum C-reactive protein elevation in left ventricular remodeling after acute myocardial infarction role-of neurohormones and cytokines显示文摘 | Toshiyuki T Toshihisa A Tsutomu Y | 2003 | International of Cardiology2003，88，2： | 1 |
| 12 | Uniaxial stress-strain relationship of concrete confined by various shaped steel tubes 显示文摘 | Susantha K A S Ge Hanbin Tsutomu Usami | 2001 | Engineering Structures2001，23，10： | 1 |
| 13 | Cyclic analysis and capacity prediction of concrete-filled steel box columns显示文摘 | Susantha K A S Ge Hanbin Usami Tsutomu | 2002 | Earthquake Engineering and Structural Dynamics2002，31，2： | 1 |
| 14 | Elution of antibodies from a Protein A column by aqueous arginine solutions显示文摘 | Tsutomu A Philo JS | 2004 | Protein Expression Purification2004，36，： | 1 |
| 15 | Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant显示文摘 | KEIGO N MASANORI A TSUTOMU A | 2002 | Biological & Pharmaceutical Bulletin2002，25，9： | 1 |
| 16 | Successful treatment of Stevens-Johnson syndrome with steroid pulse therapy at disease onset 显示文摘 | YAYOI A C HIE S TSUTOMU I | 2009 | Am J Ophtha2009，147，6： | 1 |
| 17 | Acute fatty liver of pregnancy at 23 weeks of gestation显示文摘 | Shunji S Shoichi W Tsutomu A | 2001 | Br J Obstet Gynaecol2001，108，2： | 1 |
| 18 | Angiotensin Ⅱ type 1 receptor blocker ameliorates overproduction and accumulation of triglyceride in the liver of Zucker fatty rats显示文摘 | Jianmin R Tsutomu H Mitsuru A | 2004 | Am J Physiol Endocrinol Metab2004，287，2： | 1 |
| 19 | Molecular characterization of a xylanase-producing thermophilic fungus isolated from Japanese soil显示文摘 | SOPHON B TADANORI A TSUTOMU M | 2003 | Current Microbiology2003，47，： | 1 |
| 20 | Preparation of S-doped TiO2 photocatalysts and their photoeatalytic activities under visible light 显示文摘 | TERUHISA O MIYAKO A TSUTOMU U | 2004 | Applied Catalysis2004，265，1： | 1 |
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