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    题名 作者 年代 出处 被引量
1Parthenogenetic haploid embryonic stem cells produce fertile mice显示文摘Haifeng Wan Zhengquan He Mingzhu Dong Tiantian Gu Guan-Zheng Luo Fei Teng Baolong Xia Wei Li Chunjing Feng Xin Li Tianda Li Ling Shua Rui Fu Liu Wang Xiu-Jie Wang Xiao-Yang Zhao Qi Zhou 2013Cell Research2013,23,11:13
2A data-driven method for syndrome type identification and classification in traditional Chinese medicine显示文摘The efficacy of traditional Chinese medicine(TCM) treatments for Western medicine(WM) diseases relies heavily on the proper classification of patients into TCM syndrome types.The authors developed a data-driven method for solving the classification problem,where syndrome types were identified and quantified based on statistical patterns detected in unlabeled symptom survey data.The new method is a generalization of latent class analysis(LCA),which has been widely applied in WM research to solve a similar problem,i.e.,to identify subtypes of a patient population in the absence of a gold standard.A well-known weakness of LCA is that it makes an unrealistically strong independence assumption.The authors relaxed the assumption by first detecting symptom co-occurrence patterns from survey data and used those statistical patterns instead of the symptoms as features for LCA.This new method consists of six steps:data collection,symptom co-occurrence pattern discovery,statistical pattern interpretation,syndrome identification,syndrome type identification and syndrome type classification.A software package called Lantern has been developed to support the application of the method.The method was illustrated using a data set on vascular mild cognitive impairment.Nevin Lianwen Zhang Chen Fu Teng Fei Liu Bao-xin Chen Kin Man Poon Pei Xian Chen Yun-ling Zhang 2017Journal of Integrative Medicine2017,15,2:11
3Two-in-one:A pooled analysis of primary hepatic neuroendocrine carcinoma combine d/collide d with hepatocellular carcinoma显示文摘To the Editor:Primary hepatic neuroendocrine carcinoma(PHNEC)combined/collided with hepatocellular carcinoma(HCC)is a rare and intriguing disease with characteristics of two histologically different cancers.Usually,a combined type refers to the cases in which hepatic neuroendocrine carcinoma(HNEC)and HCC components intermingle with each other and cannot be clearly separated in the transitional areas,while a collision type refers to those in which the two distinct cancers occurred simultaneously and independently.Sometimes it is difficult to readily distinguish these two types.We searched PubMed,Medline,China Science Periodical Database,and VIP Database with the publication from January 1980 to January 2019,using the keywords(“hepatic neuroendocrine carcinoma”or“HNEC”)and(“hepatocellular carcinoma”or“HCC”).After manually excluding records on secondary HNEC and other types of liver cancer,a total of 28 cases in 24 reports[1–24]were identified and summarized in Table 1.Jia-Xi Mao Fei Teng Ke-Yan Sun Cong Liu Guo-Shan Ding Wen-Yuan Guo 2020Hepatobiliary & Pancreatic Diseases International2020,19,4:6
4Two case reports and literature review for hepatic epithelioid angiomyolipoma: Pitfall of misdiagnosis显示文摘BACKGROUND Hepatic epithelioid angiomyolipoma(HEAML) is a rare liver disease and is easily misdiagnosed. Enhanced recognition of HEAML is beneficial to the differential diagnosis of rare liver diseases.CASE SUMMARY We presented two cases of HEAML in Changzheng Hospital, Naval Medical University, and then collected and analyzed all reports about HEAML recorded in PubMed, MEDLINE, China Science Periodical Database, and VIP database from January 2000 to March 2018. A total of 409 cases of HEAML in 97 reports were collected, with a ratio of men to women of 1:4.84 and an age range from 12 years to 80 years(median 44 years). Among the patients with clinical symptoms mentioned, 61.93%(205/331) were asymptomatic, 34.74%(115/331) showed upper or right upper quadrant abdomen discomfort, while a few of them showed abdominal mass, gastrointestinal symptoms, low fever, or weight loss. The misdiagnosis rate of HEAML was as high as 40.34%(165/409) due to its nonspecific imaging findings. Most of the tumors were solitary and round in morphology, with clear boundaries. Ultrasound scan indicated low echo with internal nonuniformity and rich blood supply in most cases. Computer tomography/magnetic resonance imaging enhanced scan showed varied characteristics. The ratio of fast wash-in and fast wash-out, fast wash-in and slow wash-out, and delayed enhancement was roughly 4:5:1. A definite diagnosis of HEAML depended on the pathological findings of the epithelioid cells in lesions and the expression of human melanoma black 45, smooth muscle actin,melanoma antigen, and actin by immunohistochemical staining. HEAML had a relatively low malignant rate of 3.91%. However, surgical resection was the main treatment for HEAML, due to the difficulty diagnosing before operation.CONCLUSION HEAML is a rare and easily misdiagnosed disease, and it should be diagnosed carefully, taking into account clinical course, imaging, pathological,and immunohistochemical findings.Jia-Xi Mao Fei Teng Cong Liu Hang Yuan Ke-Yan Sun You Zou Jia-Yong Dong Jun-Song Ji Jun-Feng Dong Hong Fu Guo-Shan Ding Wen-Yuan Guo 2019World Journal of Clinical Cases2019,7,8:6
5Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation显示文摘Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride(CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a doubleblinded, randomised controlled trial of 91 subjects, the impact of CPC-containing oral rinses on supragingival plaque was investigated in experimental gingivitis, where the subjects, after a 21-day period of dental prophylaxis to achieve healthy gingivae, received either CPC rinses or water for 21 days. Within-subject temporal dynamics of plaque microbiota and symptoms of gingivitis were pro?led via 16 S ribosomal DNA gene pyrosequencing and assessment with the Mazza gingival index.Cetylpyridinium chloride conferred gingival bene?ts, as progression of gingival in?ammation resulting from a lack of dental hygiene was signi?cantly slower in the mouth rinse group than in the water group due to inhibition of 17 gingivitis-enriched bacterial genera. Tracking of plaque α and β diversity revealed that CPC treatment prevents acquisition of new taxa that would otherwise accumulate but maintains the original biodiversity of healthy plaques. Furthermore, CPC rinses reduced the size, local connectivity and microbiota-wide connectivity of the bacterial correlation network, particularly for nodes representing gingivitisenriched taxa. The ?ndings of this study provide mechanistic insights into the impact of oral rinses on the progression and maturation of dental plaque in the natural human population.Fei Teng Tao He Shi Huang Cun-Pei Bo Zhen Li Jin-Lan Chang Ji-Quan Liu Duane Charbonneau Jian Xu Rui Li Jun-Qi Ling 2016International Journal of Oral Science2016,8,3:6
6Estrogen and insulin synergistically promote endometrial cancer progression via crosstalk between their receptor signaling pathways显示文摘Objective: Despite evidence that estrogens and insulin are involved in the development and progression of many cancers, their synergistic role in endometrial carcinoma(EC) has not been analyzed yet.Methods: Here, we investigated how estrogens act synergistically with insulin to promote EC progression. Cell growth in vitro and in vivo, effects of estradiol and insulin on apoptosis and cell cycle distribution, and expression and activation of estrogen receptor(ER), insulin receptor(InsR), and key proteins in the PI3K and MAPK pathways were examined after combined stimulation with estradiol and insulin.Results: Compared to EC cells treated with estradiol or insulin alone, those treated with both estradiol and insulin exhibited stronger stimulation. Estradiol significantly induced phosphorylation of InsR-β and IRS-1, whereas insulin significantly induced phosphorylation of ER-α. In addition, treatment with both insulin and estradiol together significantly increased the expression and phosphorylation of Akt, MAPK, and ERK. Notably, InsR-β inhibition had a limited effect on estradiol-dependent proliferation,cell cycle, and apoptosis, whereas ER-α inhibition had a limited insulin-dependent effect, in EC cell lines. Insulin and estradiol individually and synergistically promoted EC xenograft growth in mice.Conclusions: Estrogen and insulin play synergistic roles in EC carcinogenesis and progression by activating InsR-β and ER-α,promoting a crosstalk between them, and thereby resulting in the activation of downstream PI3K/Akt and MAPK/ERK signaling pathways.Wenyan Tian Fei Teng Jinping Gao Chao Gao Guoyan Liu Yanfang Zhang Shizhu Yu Wei Zhang Yingmei Wang Fengxia Xue 2019Cancer Biology & Medicine2019,16,1:6
7Multi-model comparison of CO2 emissions peaking in China:Lessons from CEMF01 study显示文摘The paper summarizes results of the China Energy Modeling Forum's(CEMF)first study.Carbon emissions peaking scenarios,consistent with China's Paris commitment,have been simulated with seven national and industry-level energy models and compared.The CO2 emission trends in the considered scenarios peak from 2015 to 2030 at the level of 9e11 Gt.Sector-level analysis suggests that total emissions pathways before 2030 will be determined mainly by dynamics of emissions in the electric power industry and transportation sector.Both sectors will experience significant increase in demand,but have low-carbon alternative options for development.Based on a side-by-side comparison of modeling input and results,conclusions have been drawn regarding the sources of emissions projections differences,which include data,views on economic perspectives,or models'structure and theoretical framework.Some suggestions have been made regarding energy models'development priorities for further research.Oleg LUGOVOY FENG Xiang-Zhao GAO Ji LI Ji-Feng LIU Qiang TENG Fei ZOU Le-Le 2018Advances in Climate Change Research2018,9,1:5
8A genetic diversity assessment of starch quality traits in rice landraces from the Taihu basin,China显示文摘There are nearly 1 000 rice landrace varieties in the Taihu basin, China. To assess the genetic diversity of the rice, 24 intragenic molecular markers(representing 17 starch synthesis-related genes) were investigated in 115 Taihu basin rice landraces and 87 improved cultivars simultaneously. The results show that the average genetic diversity and polymorphism information content values of the landraces were higher than those of improved cultivars. In total, 41 and 39 allele combinations(of the 17 genes) were derived from the landraces and improved cultivars, respectively; only two identical allele combinations were found bet ween the two rice variety sources. Cluster analysis, based on the molecular markers, revealed that the rice varieties could be subdivided into five groups and, within these, the japonica improved rice and japonica landrace rice varieties were in two separate groups. According to the quality reference criteria to classify the rice into grades, some of the landraces were found to perform we ll, in terms of starch quality. For example, according to NY /T595-2002 criteria from the Ministry of Agriculture of China, 25 and 33 landraces reached grade 1, in terms of their apparent amylose content and gel consistency. Th e varieties that had outstanding quality could be used as breeding materials for rice quality breeding programs in the future. Our study is useful for future applications, such as genetic diversity studies, the protection of rice variety and improvment of rice quality in breeding programs.AO Yan XU Yong CUI Xiao-fen WANG An TENG Fei SHEN Li-qun LIU Qiao-quan 2016Journal of Integrative Agriculture2016,15,3:5
9Comparison of intravitreal injection of conbercept and triamcinolone acetonide for macular edema secondary to branch retinal vein occlusion显示文摘AIM:To compare the safety and efficacy of the intravitreal injection of conbercept(IVC)and triamcinolone acetonide(IVTA)for macular edema(ME)secondary to branch retinal vein occlusion(BRVO).METHODS:A prospective,randomized clinical study.Patients with ME secondary to BRVO were randomly assigned to either IVC group or IVTA group at a ratio of 2:1 and a 12-month follow-up was performed.The efficacy outcome measures included the mean changes and differences in best corrected visual acuity(BCVA)and the central retinal thickness(CRT).The safety profiles and the mean retreatment intervals were also compared.RESULTS:There was no statistically significant difference of baseline between the two groups(IVC group,n=36;IVTA group,n=17).At 12mof the BCVA letters improved by 27.31±18.36 in the IVC group,and 13.53±11.37 in the IVTA group(P=0.0004).CRT reduction was 253.33±163.69 and 150.24±134.32 pm,respectively(P=0.0034).The mean BCVA in the IVC group was superior to that of the IVTA group for months 6-12(P<0.01).The mean CRT at 9 and 12mo were thinner in the IVC group compared to the IVTA group(P<0.01).The mean retreatment interval in the IVC group was longer than that in the IVTA group(97.40±36.27d vs 68.71±36.38d,P=0.0030).One eye in the IVC group and seven eyes in the IVTA group developed elevated intraocular pressure(IOP;P=0.0012).The proportion of eyes with cataract new-onset or progression were 19.44%in the IVC group and 64.71%in the IVTA group(P=0.0012).CONCLUSION:IVC could maintain or improve BCVA and reduce CRT for a longer time and have longer retreatment interval than IVTA.In addition,patients treated with IVTA are more susceptible to IOP elevation and cataract progression.Miao Zhao Ce Zhang Xi-Mei Chen Yan Teng Tian-Wei Shi Fei Liu 2020International Journal of Ophthalmology(English edition)2020,13,11:4
10Effects of arrangement of surge-root irrigation emitters on growth,yield and water use efficiency of apple trees显示文摘Six-year old apple trees were selected for field experiment.The objective of this study was to obtain the reasonable arrangement of surge-root irrigation emitters in apple orchards.There were three factors:the buried depth H(25,40,55 cm),the horizontal distance L(30,40,60 cm)between the emitters and the trunk of the experimental tree,and the number of the irrigation emitters N(1,2,4).The effect of the arrangement of surge-root irrigation emitters on the growth,yield and irrigation water use efficiency(IWUE)of apple trees were studied in Northern Shaanxi where the irrigation quota takes 60%-75%of the field water capacity.The results showed that the arrangement of emitters for surge-root irrigation had a significant effect on apple tree yield and IWUE,especially,the yield and IWUE reached 28388.17 kg/hm2 and 16.83 kg/m3 in treatment T3,respectively.At the same L and N levels(T1,T2,and T3),the yield and IWUE in treatment T3 were the highest,and the yields in treatments T1 and T2 were decreased by 26.22%and 31.48%,while IWUE is reduced by14.02%and 18.12%compared with T3,respectively.At the same H and N levels(T3,T4,and T5),the yield and IWUE of apple trees were decreased with increasing L level.Especially,when L was 30 cm(T3),the yield and IWUE were the highest.The same L and H levels(T3,T6,and T7)could promote the growth of apple trees when N was 2(T3).Compared with treatment T3,it was found that the increment of new shoots was decreased by 8.07%-18.71%,and the fruit diameter was decreased by 5.41%-9.11%.Therefore,two emitters should be arranged symmetrically on both sides of an apple tree,each was buried at a 40 cm depth and 30 cm away from the trunk of the tree to effectively improve the yield and IWUE of the apple tree in mountainous areas in Northern Shaanxi.LI Zhongjie FEI Liangjun HAO Kun LIU Teng CHEN Nanshu ZHANG Quanju HUANG Deliang 2020排灌机械工程学报2020,38,7:4
11A new charging scheme in an emergency department observation unit under Beijing's basic medical insurance显示文摘He Xinhua Gao Li Teng Fei Liu Changhai Wang Shuo Wu Caijun Xu Li Li Chunsheng 2014Chinese Medical Journal2014,,18:3
12Primary hepatic squamous cell carcinoma with abdominal incision metastasis after hepatectomy显示文摘To the Editor:Primary hepatic squamous cell carcinoma(PHSCC)is a rare and easily misdiagnosed disease.We reported a PHSCC case with abdominal incision metastasis after hepatectomy,and reviewed the clinical course,imaging,pathology and immunohistochemical findings.Our case may provide a better understanding of PHSCC.Jia-Xi Mao Fei Teng Hang Yuan Cong Liu Hong Fu Ke-Yan Sun Guo-Shan Ding Wen-Yuan Guo 2019Hepatobiliary & Pancreatic Diseases International2019,18,2:3
13Derivation of Germline Competent Rat Embryonic Stem Cells from DA Rats显示文摘The laboratory rat was one of the earliest mammalian species for scientific research and used as animal disease models in physiology,toxicology,behavior,immunology,and tumor-biology for over 150 years(Jacob,1999).However,rat lags far behind mouse in generating human disease models and functional genomic studies because of the lack of authentic rat embryonic stem(ES) cells(Voigt and Serikawa, 2009),whereas the first mouse ES cell line was established in 1981(Evans and Kaufman,1981).By combining two or three kinase inhibitors which target GSK3,MEK and FGF signaling pathways in serum-free N2B27 medium,germline competent rat ES cells were first derived in 2008(Buehr et al.,2008;Tianda Li Xiao-Yang Zhao Fei Teng Xin Li Minggui Jiang Wei Li Xuepeng Wang Jialiang Wang Lei Liu Zhonghua Liu Liu Wang Qi Zhou 2012Journal of Genetics and Genomics2012,39,11:3
14High powerλ~8.5μm quantum cascade laser grown by MOCVD operating continuous-wave up to 408 K显示文摘Robust quantum cascade laser(QCL)enduring high temperature continuous-wave(CW)operation is of critical importance for some applications.We report on the realization of lattice-matched InGaAs/InAlAs/InP QCL materials grown by metal-organic chemical vapor deposition(MOCVD).High interface quality structures designed for light emission at 8.5μm are achieved by optimizing and precise controlling of growth conditions.A CW output power of 1.04 W at 288 K was obtained from a 4 mm-long and 10μm-wide coated laser.Corresponding maximum wall-plug efficiency and threshold current density were 7.1%and 1.18 kA/cm2,respectively.The device can operate in CW mode up to 408 K with an output power of 160 mW.Teng Fei Shenqiang Zhai Jinchuan Zhang Ning Zhuo Junqi Liu Lijun Wang Shuman Liu Zhiwei Jia Kun Li Yongqiang Sun Kai Guo Fengqi Liu Zhanguo Wang 2021Journal of Semiconductors2021,42,11:3
15Novel Kriging-Based Decomposed-Coordinated Approach for Estimating the Clearance Reliability of Assembled Structures显示文摘Turbine blisks are assembled using blades,disks and casings.They can endure complex loads at a high temperature,high pressure and high speed.The safe operation of assembled structures depends on the reliability of each component.Monte Carlo(MC)simulation is commonly used to analyze structural reliability,but this method needs to run thousands of computations.In order to assess the clearance reliability of assembled structures in an efficient and precise manner,the novel Kriging-based decomposed-coordinated(DC)(DCNK)approach is proposed by integrating the DC strategy,the Kriging model and the importance sampling-based Markov chain(MCIS)technique.In this method,the DC strategy is used to decompose a multi-objective problem into many single-objective problems.The relationships between these many single-objectives and the overall objective are then coordinated.The Kriging model is applied to establish the limit state functions of the single-objectives and multi-objective problems,while the MCIS method is used to assess the structural assembled clearance reliability.Moreover,a highly nonlinear complex compound function is first utilized to verify the DCNK model from a mathematical perspective.Then,the reliability of an aeroengine high-pressure turbine(HPT)blade-tip radial running clearance(BTRRC)is analyzed to validate the DCNK approach by considering thermo-structural interaction.The analytical results show that the reliability is 0.9976 when the allowance value of the BTTRC is 1.7650×10^(−3)m.Compared with different methodologies(including direct simulation,the classical Kriging model,and the weighted response surface method(WRSM)),the proposed method holds obvious advantages in computing time and precision,as well as simulation efficiency and precision.The efforts of this paper provide a useful approach to analyzing assembled clearance reliability and contribute to the development of structural reliability theory.Da Teng Yunwen Feng Cheng Lu Chengwei Fei Jiaqi Liu Xiaofeng Xue 2021Computer Modeling in Engineering & Sciences2021,,11:2
16Efficacy of rigosertib, a small molecular RAS signaling disrupter for the treatment of KRAS-mutant colorectal cancer显示文摘Objective:Mutant KRAS,the principal isoform of RAS,plays a pivotal role in the oncogenesis of colorectal cancer by constitutively activating the RAF/MEK/ERK and PI3K/AKT pathways.Effective targeted therapies are urgently needed.We investigated whether rigosertib,a benzyl styryl sulfone RAS signaling disruptor,could selectively kill KRAS-mutant colorectal cancer cells.Methods:CCK-8 was used to determine the cell viability.Patient-derived tumor and cancer cell xenograft models were used to detect the inhibitory efficacy of rigosertib.Flow cytometry was used to evaluate the apoptosis and cell cycle progression.Apoptosis and cell cycle arrest markers were detected by Western blot.DCFH-DA was used to determine the reactive oxygen species.Immunohistochemistry staining and Western blot were performed to characterize RAS signaling markers in colorectal cancer tissues and cells.Results:Rigosertib(RGS)exhibited a cytotoxic effect against colorectal cancer cells,which was greater in KRAS-mutant cells.Furthermore,RGS induced mitotic arrest and oxidative stress-dependent apoptosis in KRAS-mutant DLD1 and HCT116 cells.Besides,RGS disrupted RAS signaling,and the inhibition of RAS/MEK/ERK was independent of cellular oxidative stress.Using patient-derived xenograft models,the response and tumor inhibition of RGS were significantly higher in the KRAS-mutant subgroup,while p-MEK,p-ERK,and p-AKT levels of RGS-treated tumors were significantly decreased.Finally,in a KRAS-mutant,chemotherapy-resistant patient-derived xenograft model,RGS showed a stronger therapeutic effect than the combination standard therapy involving fluoropyrimidine+oxaliplatin/irinotecan+bevacizumab.Conclusions:These data showed that targeting RAS signaling using RGS could be a therapeutic treatment for KRAS-mutant colorectal cancer patients.Xinyi Zhou Qian Xiao Dongliang Fu Haochen Zhang Yang Tang Jinjie He Yeting Hu Xiangxing Kong Fei Teng Xiangrui Liu Ying Yuan Kefeng Ding 2022Cancer Biology & Medicine2022,19,2:2
17Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors显示文摘Claudin18.2(CLDN18.2)is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer.It has been identified as a promising target and a potential biomarker to diagnose tumor,evaluate efficacy,and determine patient prognosis.TST001 is a recombinant humanized CLDN18.2 antibody that selectively binds to the extracellular loop of human Claudin18.2.In this study,we constructed a solid target radionuclide zirconium-^(89)(^(89)Zr)labled-TST001 to detect the expression of in the human stomach cancer BGC823CLDN18.2 cell lines.The[^(89)Zr]Zr-desferrioxamine(DFO)-TST001 showed high radiochemical purity(RCP,>99%)and specific activity(24.15±1.34 GBq/mmol),and was stable in 5%human serum albumin,and phosphate buffer saline(>85%RCP at 96 h).The EC_(50) values of TST001 and DFO-TST001 were as high as 0.413±0.055 and 0.361±0.058 nM(P>0.05),respectively.The radiotracer had a significantly higher average standard uptake values in CLDN18.2-positive tumors than in CLDN18.2-negative tumors(1.11±0.02 vs.0.49±0.03,P=0.0016)2 days post injection(p.i.).BGC823CLDN18.2 mice models showed high tumor/muscle ratios 96 h p.i.with[^(89)Zr]Zr-DFO-TST001 was much higher than those of the other imaging groups.Immunohistochemistry results showed that BGC823CLDN18.2 tumors were highly positive(+++)for CLDN18.2,while those in the BGC823 group did not express CLDN18.2().The results of ex vivo biodistribution studies showed that there was a higher distribution in the BGC823CLDN18.2 tumor bearing mice(2.05±0.16%ID/g)than BGC823 mice(0.69±0.02%ID/g)and blocking group(0.72±0.02%ID/g).A dosimetry estimation study showed that the effective dose of[^(89)Zr]Zr-DFO-TST001 was 0.0705 mSv/MBq,which is within the range of acceptable doses for nuclear medicine research.Taken together,these results suggest that Good Manufacturing Practices produced by this immuno-positron emission tomography probe can detect CLDN18.2-overexpressing tumors.Yan Chen Xingguo Hou Dapeng Li Jin Ding Jiayue Liu Zilei Wang Fei Teng Hongjun Li Fan Zhang Yi Gu Steven Yu Xueming Qian Zhi Yang Hua Zhu 2023Journal of Pharmaceutical Analysis2023,13,4:2
18A reduced-order extrapolation algorithm based on CNLSMFE formulation and POD technique for two-dimensional Sobolev equations显示文摘A reduced-order extrapolation algorithm based on Crank-Nicolson least-squares mixed finite element(CNLSMFE) formulation and proper orthogonal decomposition(POD)technique for two-dimensional(2D) Sobolev equations is establishedThe error estimates of the reduced-order CNLSMFE solutions and the implementation for the reduced-order extrapolation algorithm are providedA numerical example is used to show that the results of numerical computations are consistent with theoretical conclusionsMoreover, it is shown that the reduced-order extrapolation algorithm is feasible and efficient for seeking numerical solutions to2D Sobolev equations.LIU Qun TENG Fei LUO Zhen-dong 2014Applied Mathematics(A Journal of Chinese Universities)2014,29,2:2
19Emission Enhancement of Fluorescent Molecules by Antireflective Arrays显示文摘Traditional fluorescence enhancement based on a match of the maximum excitation or emission of fluorescence molecule with the spectra of the nanostructure can hardly enhance blue and red fluorescent molecules.Here,an enhanced method which is a new strategy based on the antireflective array has been developed to enhance the emission of blue and red fluorescent molecules.The fluorescence emission is enhanced by increasing the absorption at excitation wavelengths of the fluorescent molecules and reducing the fluorescent energy dissipation with an antireflective array.By introducing the antireflective arrays,the emission enhancement of blue and red fluorescent molecules is,respectively,up to 14 and 18 fold.It is a universal and effective strategy for enhancing fluorescence emission,which could be applied to enhance the intensity of organic LED and imaging.Hongbo Xu Lingxiao Liu Fei Teng Nan Lu 2019Research2019,,1:2
20Tailoring of electromagnetic field localizations by twodimensional graphene nanostructures显示文摘Graphene has great potential for enhancing light−matter interactions in a two-dimensional regime due to surface plasmons with low loss and strong light confinement.Further utilization of graphene in nanophotonics relies on the precise control of light localization properties.Here,we demonstrate the tailoring of electromagnetic field localizations in the mid-infrared region by precisely shaping the graphene into nanostructures with different geometries.We generalize the phenomenological cavity model and employ nanoimaging techniques to quantitatively calculate and experimentally visualize the two-dimensional electromagnetic field distributions within the nanostructures,which indicate that the electromagnetic field can be shaped into specific patterns depending on the shapes and sizes of the nanostructures.Furthermore,we show that the light localization performance can be further improved by reducing the sizes of the nanostructures,where a lateral confinement of λ0/180 of the incidence light can be achieved.The electromagnetic field localizations within a nanostructure with a specific geometry can also be modulated by chemical doping.Our strategies can,in principle,be generalized to other two-dimensional materials,therefore providing new degrees of freedom for designing nanophotonic components capable of tailoring two-dimensional light confinement over a broad wavelength range.Ze-Bo Zheng Jun-Tao Li Teng Ma Han-Lin Fang Wen-Cai Ren Jun Chen Jun-Cong She Yu Zhang Fei Liu Huan-Jun Chen Shao-Zhi Deng Ning-Sheng Xu 2017Light(Science & Applications)2017,6,1:2
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