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3篇 您的检索式:作者名="Tai Young Ahn"
    题名 作者 年代 出处 被引量
1Treatment preferences in men with erectile dysfunction: an open label study in Korean men switching from sildenafil citrate to tadalafil显示文摘瞄准:为 sildenafil 柠檬酸盐或 tadalafil 评估耐心的偏爱(为可勃起的机能障碍的治疗可得到的 PDE-5 禁止者[编辑]) 并且为这些偏爱估计潜在的原因。方法:这开标签的研究在拿 sildenafil 的朝鲜的人,上被进行在学习入口以前的至少 6 个星期为编辑追随者屏蔽,病人们继续 sildenafil 治疗 4 个星期,然后在一个 1 星期的冲刷时期以后,换到 tadalafil 8 个星期。病人们然后在一个延期阶段期间继续了他们选择的治疗。Psychosocial 因素(时间担心,自然,性自信) 用心理、人与人之间的关系规模(对) 被评估,当剂量预定到性尝试时,模式从耐心的日记被估计。结果:现在的学习注册了 160 个朝鲜的人(意味着年龄 55 年) 与 585 天的优先的中部的 sildenafil 使用。在延期阶段期间, 73.7% 病人选择拿 tadalafil,而 26.3% 选择了 sildenafil (P < 0.001 ) 。在从 sildenafil 切换到 tadalafil 以后,意味着担心分数从 2.54 ~ 2.42 减少了的对时间(P = 0.002 ) ,没有统计上,有效差量在性自然和自信分数在 sildenafil 和 tadalafil 评价阶段之间观察了。做的性尝试 < 4 h 到≤ 36 h 剂量以后在 tadalafil 评价阶段期间与 17.5% 相比在 sildenafil 评价阶段期间发生在 4.5% 病人。结论:在经历 sildenafil 和 tadalafil 以后,病人的多数为 tadalafil 展出了偏爱。这偏爱可能被精神分析聚会因素影响,例如减少的时间担心,和为性欲活动可得到的机会的一扇更宽广的窗户。Tai Young Ahn Sung Won Lee Sae-Woong Kim Dae Yul Yang Nam Cheol Park Kweon-Sik Min Kwangsung Park Jae-Seung Paick Yulia Dyachkova Trisha Dwight Myung-Sea Luke Lee 2007Asian Journal of Andrology2007,9,6:3
2High-frequency magnetic stimulation attenuates beta-amyloid protein 1-42 neurotoxicity in organotypic hippocampal slices显示文摘Repetitive transcranial magnetic stimulation (rTMS) has been utilized as a therapeutic tool for neurodegenerative disorders including Alzheimer’s disease.However,the precise mechanisms of its clinical effects remain unknown.β-amyloid (Aβ) exhibits direct neurotoxic effects and is closely related to neuronal degeneration in Alzheimer’s disease.Therefore,it has been hypothesized that the neuroprotective effects of rTMS are related to the mechanisms of protection against Aβ neurotoxicity.Organotypic hippocampal slices were prepared from 8-day old,Sprague Dawley rats.The tissue slices were exposed to 100 μmol/L Aβ1-42 since day 12 in vitro with and without high-frequency (20 Hz) magnetic stimulation.Magnetic stimulation efficacy was evaluated by measuring neuronal nuclei (NeuN) protein expression and by observing cultures following propidium iodide fluorescence staining and bromodeoxyuridine (BrdU) immunohistochemistry.Lactate dehydrogenase activity was detected in the culture media to evaluate hippocampal neuronal damage.Our results demonstrated that high-frequency magnetic stimulation significantly reversed the reduction of NeuN protein expression because of Aβ1-42 exposure (P < 0.05) and significantly reduced the number of damaged cells in the hippocampal slices (P < 0.05).However,lactate dehydrogenase levels and anti-BrdU staining results did not reveal any statistical differences.These findings indicate that high-frequency magnetic stimulation might have protective effect on hippocampal neurons from Aβ1-42 neurotoxicity.Don-Kyu Kim Young Chul Yoon Soo Ahn Chae Kyung Mook Seo Tai Ryoon Han Si-Hyun Kang 2010Neural Regeneration Research2010,5,18:2
3Structure–activity relationship of lupane-triterpene glycosides from Acanthopanax koreanum on spleen lymphocyte IL-2 and IFN-γ显示文摘Nguyen Xuan Nhiem Phan Van Kiem Chau Van Minh Bui Huu Tai Nguyen Huu Tung Do Thi Ha Kwang Su Soung Jun Ho Kim Ji Young Ahn Young-Mi Lee Young Ho Kim 2010Bioorganic & Medicinal Chemistry Letters2010,,16:1
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