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34篇 您的检索式:作者名="Su EJ"
    题名 作者 年代 出处 被引量
1Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies显示文摘Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood.We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients.After classifying individual cells;we generated a spatial and temporal landscape of glioma that revealed the patterns of invasion between the different sub-regions of gliomas.We also used single-cell inferred copy number variations and pseudotime trajectories to inform on the crucial branches that dominate tumor progression.The dynamic cell components of the multi-region biopsy analysis allowed us to spatially deconvolute with unprecedented accuracy the transcriptomic features of the core and those of the periphery of glioma at single-cell level.Through this rich and geographically detailed dataset,we were also able to characterize and construct the chemokine and chemokine receptor interactions that exist among different tumor and non-tumor cells.This study provides the first spatial-level analysis of the cellular states that characterize human gliomas.It also presents an initial molecular map of the cross-talks between glioma cells and the surrounding microenvironment with single-cell resolution.Kai Yu Yuqiong Hu Fan Wu Qiufang Guo Zenghui Qian Waner Hu Jing Chen Kuanyu Wang Xiaoying Fan Xinglong Wu John EJ Rasko Xiaolong Fan Antonio lavarone Tao Jiang Fuchou Tang Xiao-Dong Su 2020National Science Review2020,7,8:4
2Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization显示文摘Su EJ Cioffi CL Stefansson S 2003Am J Physiol Heart Circ Physiol2003,284,4:1
3Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization显示文摘Su EJ Cioffi CL Stefansson S 2003Am J Physiol Heart Circ Physiol2003,284,:1
4Angiotensin Ⅱ induces vascular smooth muscle cell replication independent of blood pressure显示文摘 Lombardi DM Siegal J 1998Hypertens1998,31,:1
5Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization显示文摘Su EJ Cioffi CL Stefansson S Mittereder N Garay M Hreniuk D 2003Am J Physiol Heart Circ Physiol2003,284,4:1
6Bioactive constituents of the seeds brucea javanica显示文摘Su BN Chang LCH Park EJ 2002Planta Med2002,68,8:1
7A fully liquid DTPw-HepB-Hib combination vaccine for booster vaccination of tod-dlers in El Salvador显示文摘Suárez E Asturias EJ Hilbert AK 2010Rev Panam Salud Publica2010,27,2:1
8Intra-biliary contrast-enhanced ultrasound for evaluating biliary obstruction during percutaneous transhepatic biliary drainage:a preliminary study显示文摘Xu EJ Zheng RQ Su ZZ 0,,12:1
9Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor action in animal models显示文摘Cao B Su Y Oskarsson M Zhao P Kort EJ Fisher RJ Wan LM Vande Woude GF 0,,:1
10Angiotensin Ⅱ induces vascular smooth muscle cell replication independent of blood pressure显示文摘Su EJ Lombardi DM SIEGAL J 1998Hypertension1998,31,:1
11Activation of PDGF- CC by tissue plasminogen activator impairs blood-brain barrier in- tegrity during ischemic stroke 显示文摘SU EJ FREDRIKSSON L GEYER M 2008Nat Med2008,14,7:1
12The contribu-tions of integrin affinity and integrin-cytoskeletal en- gagement in endothelial and smooth muscle cell adhe- sion to vitroneetin显示文摘Stefansson S Su EJ Ishigami S 2007Journal of Biological Chemistry2007,282,15:1
13Tissue plas- minogen activator-mediated PDGF signaling and neurovascular coupling in stroke显示文摘SU EJ FREDRIKSSON L SCHIELKE GP 2009J Thromb Haemost2009,7,1:1
14Bioative constituents of the seeds of Brucea javanica显示文摘Su BN Chang LC Park EJ 2002Planta Medica2002,68,8:1
15Diverticular disease of the small bowel显示文摘Chiu EJ Shyr YM Su CH 2000Hepatogastroenterology2000,47,31:1
16Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischaemic stroke显示文摘Su EJ Fredriksson L Geyer M 2008Nat Med2008,14,7:1
17Scapular rotation in swimmers with and without impingement syndrome: prac- tice effects显示文摘Su KP Johnson MP Gracely EJ 2004Med Sci Sports Exerc2004,36,:1
18Bioactive constituents of the seeds of brucea javanica显示文摘Su BN Chang LC Park EJ 2002Planta Med2002,68,6:1
19Effects of temperatureand sodium chloride concentration on the activities of proteasesand amylases in soy sauce koji显示文摘Su N W Wang M L Kwok K F eJ al 2005Journal of Agricultural andFood Chemistry2005,53,5:1
20Remodeling of the temporomandibular joint following mandibular distraction osteogenesis in the transverse dimension显示文摘 Stucki-McCormick SU Rowe N 2001Plast Reconstr Surg2001,107,3:1
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