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| 1 | Stratal slicing,part II:Real 3-D seismic data显示文摘 | Zeng Hongliu Stephen C Henry John P Riola | 1998 | Geopgysics1998，63，2： | 1 |
| 2 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 3 | Stratal slicing, partII: real 3-D seismic clata显示文摘 | Zeng H L Stephen C Henry John P Riola | 1998 | Geophysics1998，63，2： | 1 |
| 4 | Stratal slicing, part Ⅱ : Real 3 - Dseismic data显示文摘 | Hongliu Zeng Henry Stephen C Riola jonil P | 1998 | Geophysics1998，63，51： | 1 |
| 5 | Stratal slicing, part II : Real 3 - D seismic data显示文摘 | Zeng Hongliu Henry Stephen C Riola John P | 1998 | Geophysics1998，63，2： | 1 |
| 6 | Stratal slicing, partⅡ :Real 3 - D seismic data显示文摘 | ZENG HONGLIU HENRY STEPHEN C RIOLA JOHN P | 1998 | Geophysics1998，63，2： | 1 |
| 7 | Stratal slicing, part II: Real 3 - D seismic data 显示文摘 | HONGLIU ZENG STEPHEN C HENRY JOHN P RIOLA | 1998 | Geopgysics1998，63，2： | 1 |
| 8 | Stratal slicing, part II : Real 3 - D seismic data 显示文摘 | HONGLIU ZENG STEPHEN C HENRY JOHN P RIOLA | 1998 | Geopgysics1998，63，2： | 1 |
| 9 | Stratalslicing,partⅡ:Real 3-D seismic data显示文摘 | Zeng Hongliu Henry Stephen C Riola John P | 1998 | Geophysics1998，63，2： | 1 |
| 10 | Stratal slicing,part lIReal 3 D seismic data显示文摘 | Zeng Hongliu Stephen C Henry John P Riola | 1998 | Geopgysics1998，63，2： | 1 |
| 11 | Stratal slicing,part,Ⅱ:Realistic 3D seismic model显示文摘 | HongliuZeng Stephen C Henry | 1998 | Geophysics1998，63，2： | 1 |
| 12 | Strata Slicing: Part Ⅱ, Real 3-D seismic data显示文摘 | Zeng Hongliu Henry C Stephen Riola P John | 1998 | Geophysics1998，63，2： | 1 |
| 13 | Stratal Slicing: Part I: Realistic 3-D Seismic Model显示文摘 | Zeng Hongliu Stephen C Henry John P Riola | 1998 | Geo- physics1998，63，2： | 1 |
| 14 | Stratal Slicing: Part II: Real 3-D Seismic Data显示文摘 | Zeng Hongliu Stephen C Henry John P Riola | 1998 | Geophysies1998，63，2： | 1 |
| 15 | Droplet Aerodynam- ics, Cellular Uptake, and Efficaey of a Nebulizable Cortico- steroid Nanosuspension are Superior to a Micronized Dosage Form 显示文摘 | Stephen B Wayne F Henry C | 2012 | Biotechnology Progress2012，28，5： | 1 |
| 16 | Stratal sli- cing, Part II : real 3-D seismic data 显示文摘 | Zeng Hong-liu Henry Stephen C Riola John P | 1998 | Geophysics1998，63，2： | 1 |
| 17 | Group decision process and incrementalism in organizational decision making 显示文摘 | Henry M Donald E C Stephen E H | 2003 | Organizational Behavior and Human Decision Processes2003，92，12： | 1 |
| 18 | Stratal slicing ,part II :Real 3D seismic data显示文摘 | Zeng Hongliu Henry Stephen C Riola John P | 1998 | Geophysics1998，63，2： | 1 |
| 19 | Strata slicing, part II : Real 3-D seismic data 显示文摘 | Zeng Hong-liu Henry Stephen C Riola John P | 1998 | Geophysics1998，63，2： | 1 |
| 20 | Stratal slicing, Part Ⅱ: real 3 -D seismic data显示文摘 | Zeng Hongliu Henry Stephen C Riola John | 1998 | Geophysics1998，63，2： | 1 |
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