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| 1 | Retrospective analysis of old-age colitis in the Dutch inflammatory bowel disease population显示文摘AIM: To describe the characteristics of Dutch patients with chronic inflammatory bowel disease (IBD) first diagnosed above 60 years of age-a disease also known as old-age colitis (OAC) and to highlight a condition that has a similar appearance to IBD, namely segmen- tal colitis associated with diverticular disease (SCAD). METHODS: A retrospective longitudinal survey of patient demographic and clinical characteristics, disease characteristics, diagnostic methods, management and course of disease was performed. The median follow-up period was 10 years. RESULTS: Of a total of 1100 IBD patients attending the Department of Gastroenterology, 59 (5%) [median age 82 years (range 64-101); 25 male (42%)] were identified. These patients were diagnosed with ulcerative colitis (n = 37, 61%), Crohn’s disease (n = 14, 24%), and indeterminate colitis (n = 8, 15%). Remission was induced in 40 (68%) patients within a median interval of 6 mo (range 1-21) and immunosuppressive therapy was well tolerated. Histological evaluation based on many biopsy samples and the course of the disease led to other diagnosis, namely SCAD instead of IBD in five (8%) patients. CONCLUSION: OAC is not an infrequent problem for the gastroenterologist, and should be considered in the evaluation of older patients with clinical featuressuggestive of IBD. Extra awareness and extensive biopsy sampling are required in order to avoid an erroneous diagnosis purely based on histological mimicry of changes seen in SCAD, when diagnosing IBD in the presence of diverticulosis coli. | Muhammed Hadithi Marcel Cazemier Gerrit A Meijer Elisabeth Bloemena Richel J Felt-Bersma Chris J Mulder Stephan GM Meuwissen Amado Salvador Pea Adriaan A van Bodegraven | 2008 | World Journal of Gastroenterology2008，14，20： | 3 |
| 2 | Entry of hepatitis B and C viruses — recent progress and future impact显示文摘 | Thomas F Baumert Luke Meredith Yi Ni Daniel J Felmlee Jane A McKeating Stephan Urban | 2013 | Current Opinion in Virology2013，，： | 3 |
| 3 | Selective interaction of a semiconjugated organic polymer with single-wall nanotubes 显示文摘 | Dalton A Stephan C Coleman J N | 2000 | J Phys Chem B2000，104，10： | 1 |
| 4 | Intraday price change and trading volume relations in the stock and stock option markets 显示文摘 | Stephan J A Whaley R E | 1990 | The Journal of Finance1990，45，1： | 1 |
| 5 | Supply Chain Design in the Food Industry显示文摘 | Jack G A J Vorst Stephan J van Dijk Adrie J M Beulens | 2001 | The International Journal on Logistics Management2001，12，2： | 1 |
| 6 | Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors显示文摘 | Schwermer M Lee S K?ster J van Maerken T Stephan H Eggert A | 2015 | Oncotarget2015，6，15： | 1 |
| 7 | Advanced glycation end-products(AGEs) and heart failure:Pathophysiology and clinical implications显示文摘 | JASPER W L H ADRIAAN A V STEPHAN J L B | 2007 | Eurapean Journal of Heart Failure2007，，9： | 1 |
| 8 | Treatment of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins,steroids and cyclosporin A显示文摘 | Stephan JL Donadieu J Ledeist F Blanche S Griscelli C Fischer A | 1993 | Blood1993，82，8： | 1 |
| 9 | Outcrop expression of a continental-margin-scale shelf-edge delta from the cretaceous magallanes basin显示文摘 | Covanh A J Romans W B Stephan A G | 2009 | Chile Journal of Sedimentary Research2009，79，： | 1 |
| 10 | Intraday price changes and trading volume relations in the stock and stock option markets显示文摘 | Stephan J A Whaley R E | 1990 | Journal of Finance1990，45，： | 1 |
| 11 | Myocardial failure in cats associated with low plasmataurine :a reversible cardiomy pathy显示文摘 | HAYES K C STEPHAN Z F STURMAN J A | 1987 | Science1987，14，： | 1 |
| 12 | Methodologies for the assembly of a fiber-coupled MEMS Fourier transform spectrometer显示文摘 | MAYYAS M A SIN J STEPHANOU H | 2009 | Transactions on Components and Packaging Technologies(S1521-3331)2009，32，： | 1 |
| 13 | Identification of a microRNA signatureof renal ischemia reperfusion injury显示文摘 | Godwin J G Ge X Stephan K Jurisch A Tullius S G Iacomini J | 2010 | Proc Natl AcadSci USA2010，107，14： | 1 |
| 14 | Multifractal Detrended Fluctuation Analysis of Nonstationary Time Serics显示文摘 | Kantelhardt J W Stephan A Z Eva K B | 2002 | Physics A2002，316，： | 1 |
| 15 | Evaluation of the coomassie brilliant blue G-250 method for urinary Protein显示文摘 | Lott J A Stephan V A Pritchard K A | 1983 | Clinical Chemistry1983，29，11： | 1 |
| 16 | Diagenetic alteration of calcitic fossil shells: Proton microprobe (PIXE) as a trace element tool 显示文摘 | Bruckschen P Bruhn F Meijer J Stephan A Veizer J | 1995 | Nucl Instr Method Phys ResB1995，104，14： | 1 |
| 17 | Who's patenting in the university? Evidence from the survey of doctorate recipients显示文摘 | STEPHAN P E GURMU S SUMELL A J BLACK G C | 2007 | Economics of Innovation and New Technology2007，16，2： | 1 |
| 18 | Long-term oncological and continence outcomes after laparoscopic radical prostatectomy:a single-centre experience显示文摘 | Busch J Stephan C Herold A | 2012 | BJU Int2012，，11： | 1 |
| 19 | ACC/AHA 2002 guideline update for the management of patients with chronic stable angina—summary article显示文摘 | Raymond J Gibbons Jonathan Abrams Kanu Chatterjee Jennifer Daley Prakash C Deedwania John S Douglas T.Bruce Ferguson Stephan D Fihn Theodore D Fraker Julius M Gardin Robert A O’Rourke Richard C Pasternak Sankey V Williams Raymond J Gibbons Joseph S Alpert | 2003 | Journal of the American College of Cardiology2003，，1： | 1 |
| 20 | Diagnostic, prognostic and therapeutic implications of microRNAs in urologic tumors 显示文摘 | Schaefer A Stephan C Busch J | 2010 | Nat Rev Urol2010，7，5： | 1 |
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