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| 1 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 2 | Multiplication of human immunodeficiency virus in primary cultures of human kupffer cells-possible role of liver macrophage infection in the physiopathology of AIDS显示文摘 | Steffan A M Gendranlt J L | 1990 | Res Virol1990，141，： | 1 |
| 3 | Carbon-Carbon Double Bond Versus Carbonyl Group Hydrogenation: Controlling the Intramolecular Selectivity with Polyaniline-Supported Platinum Catalysts显示文摘 | Steffan M Klasovsk F Arras J | 2008 | Adv Synth Catal2008，350，9： | 1 |
| 4 | In vitro study of ingested coins: leave them or retrieve them 显示文摘 | Rebhandl W Milassin A Brunner L Steffan I Benk T H? rmann M Burtscher J | 2007 | Pediatr Surg2007，42，10： | 1 |
| 5 | A strong regioregularity effect in self-organizing conjugated polymer films and high-efficiency polythio- phene : fullerene solar cells 显示文摘 | Steffan C Sachetan M Saehetan M | 2006 | Nat Mter2006，5，3： | 1 |
| 6 | The promoting effect of a dicyanamide based ionic liquid in the selective hydrogenation of citral显示文摘 | ARRAS J STEFFAN M SHAYEGHI Y | 2008 | Chem Commun2008，34，： | 1 |
| 7 | Virtual-flux-based direct power control of three-phase PWM rectifiers显示文摘 | Mariusz M Marian P K Steffan H | 2001 | IEEE Transactions on IndustryApplications2001，37，4： | 1 |
| 8 | A novel type of triterpenoid quinone methide pigment from the toadstool Russula flavida (Agaricales)显示文摘 | FRIODE R BRIICKEIMANN M STEFFAN B | 1995 | Tetrahedron1995，51，9： | 1 |
| 9 | A novel type of triterpenoid quinone methide pigment from the toadstool Russula flavida(Agaricales)显示文摘 | FRIODE R BRIICKEIMANN M STEFFAN B | 1995 | Tetrahedron1995，51，9： | 1 |
| 10 | Site directed mutagenesis by overlap extension using the polyme rase chain reaction显示文摘 | STEFFAN N H HENRY D H ROBERT M H | 1989 | Gene1989，77，1： | 1 |
| 11 | Architecture and evolution of upper fan channel-belts on the Niger Delta slope and in the Arabian sea显示文摘 | Deptuck M E Steffans G S Barton M | 2003 | Marine and Petroleum Geology2003，20，： | 1 |
| 12 | Determination of 28 selectedelements in textiles by axially viewed inductively coupled plasmaoptical emission spectrometry显示文摘 | REZIC I ZEINER M STEFFAN I | 2011 | Talanta2011，83，3： | 1 |
| 13 | Synthesis of arcyriarubin B and related bisindolylmaleimides显示文摘 | Brenner M Rexhausen H Steffan B | 1988 | Tetrahedron1988，44，： | 1 |
| 14 | Polymerase chain reactions applications in environmental microbiology显示文摘 | STEFFAN R J ALTAS R M | 1991 | Annu Rev Microbiol1991，，45： | 1 |
| 15 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction 显示文摘 | Henry D H Robert M H | 1989 | Gene1989，77，： | 1 |
| 16 | Trace elemental characterization of edible oils by ICP - AES and GFAAS 显示文摘 | CINDRIC I J ZEINER M STEFFAN I | 2007 | Microchemical Journal2007，85，1： | 1 |
| 17 | Architecture and evolution of upper fan channel-belts on the Niger Delta slope and in the Arabian Sea显示文摘 | Deptuck M E Steffans G S Barton M | 2003 | Marine and Petroleum Geology2003，20，： | 1 |
| 18 | Trace elemental characterization of edible oils by ICP-AES and GFAAS 显示文摘 | Cindric I J Zeiner M Steffan I | 2007 | Microchemical Journal2007，85，1： | 1 |
| 19 | Determination of trace elements in olive oil by ICP-AES and ETA-AAS: A pilot study on the geographical characterization 显示文摘 | Zeiner M Steffan I Cindric I J | 2005 | Microchemical Journal2005，81，2： | 1 |
| 20 | A novel type of triterpenoid quinone methide pigment from the toadstool Russulaflavida (Agarieales)显示文摘 | FRIODE R BRIICKEIMANN M STEFFAN B | | 0，，09： | 1 |
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