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| 1 | Photoactivated CRY1 and phyB Interact Directly with AUX/IAA Proteins to Inhibit Auxin Signaling in Arabidopsis显示文摘光是在 Arabidopsis 通过蓝色和调停 cryptochrome 的 red/far-red 光光敏电阻器和调停 phytochrome 的小径禁止胚轴房间延伸的关键环境暗示。相反,作为枢轴的内长的植物激素,植物生长素通过 AUX/IAA 蛋白质(AUX/IAAs ) 的植物生长素受体 TIR1/AFBs-mediated 降级支持胚轴延伸。然而,位于发信号的光和植物生长素的对抗相互作用下面的分子的机制仍然保持不清楚。这里,我们报导光禁止由 cryptochrome 的蓝、红的轻依赖者的相互作用通过 AUX/IAAs 的稳定发信号的植物生长素 1 (CRY1 ) 并且有 AUX/IAAs 的 phytochrome B 分别地。有 AUX/IAAs 的 CRY1 的蓝被触发光的相互作用与 AUX/IAAs 禁止 TIR1 的协会,导致这些蛋白质的导致植物生长素的降级的压抑。我们的结果显示光敏电阻器下游地直接作为一样与植物生长素受体分享 AUX/IAAs 表明部件。我们建议由光敏电阻器和植物生长素受体的 AUX/IAA 蛋白质稳定性的那条对抗规定允许植物平衡光和植物生长素信号优化他们的生长。 | Feng Xu Shengbo He Jingyi Zhang Zhilei Mao Wenxiu Wang Ting Li Jie Hua Shasha Du Pengbo Xu Ling Li Hongli Lian Hong-Quan Yang | 2018 | Molecular Plant2018，11，4： | 24 |
| 2 | Geological factors controlling deep geothermal anomalies in the Qianjiaying Mine,China显示文摘Here,the geological factors controlling deep geothermal anomalies in mines were studied based on the geotemperature,lithologic thermal conductivity,and related geological data collected from the Qianjiaying Mine,China.A simulation of the change in magma waste heat,conducted using the ANSYS Workbench,revealed the distribution characteristics of geothermal anomalies in this mine and the corresponding geological control factors.The results revealed the following points.(1)First-degree heat hazard level(temperature=31-37℃)occurred in the central and southwestern parts of the mine at an^600-m depth,while second-degree heat hazard level(temperature≥37℃)occurred at an^800-m depth.The geotemperature and geothermal gradient in the southwestern part of the mine were anomalously high.(2)The geotemperatures measured in the mine generally reflected a standard increase with depth,while the geothermal gradient remained unchanged with depth.The geothermal gradient and its average value in the study area were 0.70-4.23 and 2.12C·hm^-1,respectively.(3)A combination of stratum characteristics,geological structure,and groundwater characteristics led to geothermal anomalies in mines;additionally,the waste heat from magma had no significant effect on the geothermal field. | Wenbin Yang Shengbo Han Wu Li | 2020 | International Journal of Mining Science and Technology2020，30，6： | 5 |
| 3 | Adsorption and mechanistic study of the invasive plant-derived biochar functionalized with CaAl-LDH for Eu(Ⅲ) in water显示文摘Herein,we developed the invasive plant-derived biochar (IPB) functionalized with CaAl-LDH at five mass ratios using a physical mixture method,assessed their adsorption perform for Eu(Ⅲ),and explored the relative mechanisms.Results show that the IPB successfully loaded CaAl-LDH in five composites and their Eu(Ⅲ) sorption affinities were strongly affected by solution p H,contact time,temperature,and the mass ratio of LDH and IPB.All the sorpiton process for Eu(Ⅲ) occurred on the heterogeneous surface of five composites and the boundary layer diffusion limited the chemical sorption rate.Interestingly,the CaAl-LDH/IPB composite with high ratio of IPB had higher sorption capacity than the one with high ratio of LDH due to larger porosity of the former.Three mechanisms containing ion exchange between Al and Eu ions,surface complexation with carboxyl-and oxygen-containing functional groups,and precipitation were involved in the Eu(Ⅲ) sorption,but the dominant sorption mechanism for each CaAl-LDH/IPB composite differed with different mass ratio of CaAl-LDH and IPB.In composite with more IPB (e.g.,CaAl-LDH/IPB-13),both ion exchange and surface complexes dominated the sorption process and the intensity of Eu^3+ was identified with the one of Eu2O3.Whereas in composites with high LDH,ion exchange dominated the sorption and the intensity of Eu^3+ was obviously higher than the one of Eu_2O_3.This research will provide a new perspective for the application of the LDH/biochar materials. | Shengbo Li Lijia Dong Zuofu Wei Guodong Sheng Kui Du Baowei Hu | 2020 | Journal of Environmental Sciences2020，32，10： | 5 |
| 4 | End-to-End Autonomous Driving Through Dueling Double Deep Q-Network显示文摘Recent years have seen the rapid development of autonomous driving systems,which are typically designed in a hierarchical architecture or an end-to-end architecture.The hierarchical architecture is always complicated and hard to design,while the end-to-end architecture is more promising due to its simple structure.This paper puts forward an end-to-end autonomous driving method through a deep reinforcement learning algorithm Dueling Double Deep Q-Network,making it possible for the vehicle to learn end-to-end driving by itself.This paper firstly proposes an architecture for the end-to-end lane-keeping task.Unlike the traditional image-only state space,the presented state space is composed of both camera images and vehicle motion information.Then corresponding dueling neural network structure is introduced,which reduces the variance and improves sampling efficiency.Thirdly,the proposed method is applied to The Open Racing Car Simulator(TORCS)to demonstrate its great performance,where it surpasses human drivers.Finally,the saliency map of the neural network is visualized,which indicates the trained network drives by observing the lane lines.A video for the presented work is available online,http://gffzz6712f30e645c4b03s5o09ox5qq0vv6vuf.ffgz.tsg.suse.edu.cn/76ciJ mIHMD8 or http://gffzz9886e3e54abf46a9s5o09ox5qq0vv6vuf.ffgz.tsg.suse.edu.cn/v_show/id_XNDM4 ODc0M TM4NA==.html. | Baiyu Peng Qi Sun Shengbo Eben Li Dongsuk Kum Yuming Yin Junqing Wei Tianyu Gu | 2021 | Automotive Innovation2021，4，3： | 5 |
| 5 | Robust cooperation of connected vehicle systems with eigenvalue-bounded interaction topologies in the presence of uncertain dynamics显示文摘 | Keqiang LI Feng GAO Shengbo Eben LI Yang ZHENG Hongbo GAO | 2018 | Frontiers of Mechanical Engineering2018，13，3： | 3 |
| 6 | In situ fabrication of organic electrochemical transistors on a microfluidic chip显示文摘Microfluid chips integrating with organic electrochemical transistors (OECTs) are useful for manufacturing biosensors with high throughput and large-scale analyses. We report here the utilization of alternating current (AC) electrodeposition to fabricate OECTs in situ on a microfiuid chip. With this method, the organic semiconductor (OS) layer with a channel length of 8μm was readily prepared without requiring the postbonding process in the conventional construction of microfluidic chips. Poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate)/graphene quantum dots (PEDOT:PSS/GQDs) composites with different morphologies, such as microfilms, nanodendrites and nanowires were electropolymerized. The mass transfer process of the electropolymerization reaction was evidenced to be diffusion limited. Morphologies, growth directions, and chemical structures of OS layers could be tuned by the amplitude and the frequency of the AC voltage. Transfer and output characteristic curves of OECTs were measured on the microfluidic chip. The maximum transconductance, on/off current ratio and threshold voltage measured in the experiment was 1.58 mS, 246, and 0.120 V, respectively. | Jianlong Ji Mangmang Li Zhaowei Chen Hongwang Wang Xiaoning Jiang Kai Zhuo Ying Liu Xing Yang Zhen Gu Shengbo Sang Yang Shu | 2019 | Nano Research2019，12，8： | 3 |
| 7 | Japanese Encephalitis Virus NS1' Protein Antagonizes Interferon Beta Production显示文摘Japanese encephalitis virus(JEV) is a mosquito-borne virus and the major cause of viral encephalitis in Asia. NS1', a52-amino acid C-terminal extension of NS1, is generated with a-1 programmed ribosomal frameshift and is only present in members of the Japanese encephalitis serogroup of flaviviruses. Previous studies demonstrated that NS1' plays a vital role in virulence, but the mechanism is unclear. In this study, an NS1' defected(rG66A) virus was generated. We found that rG66A virus was less virulent than its parent virus(pSA14) in wild-type mice. However, similar mortality caused by the two viruses was observed in an IFNAR knockout mouse model. Moreover, we found that rG66A virus induced a greater type Ⅰ interferon(IFN) response than that by pSA14, and JEV NS1' significantly inhibited the production of IFN-b and IFN-stimulated genes. Taken together, our results reveal that NS1' plays a vital role in blocking type I IFN production to help JEV evade antiviral immunity and benefit viral replication. | Dengyuan Zhou Fan Jia Qiuyan Li Luping Zhang Zheng Chen Zikai Zhao Min Cui Yunfeng Song Huanchun Chen Shengbo Cao Jing Ye | 2018 | Virologica Sinica2018，33，6： | 3 |
| 8 | Elimination of CD4^low HLA-G^+ T cells overcomes castration- resistance in prostate cancer therapy显示文摘 | Chao Wang Jiahuan Chen Qianfei Zhang Wang Li Shengbo Zhang Yanjie Xu Fang Wang Bing Zhang Yan Zhang Wei-Qiang Gao | 2018 | Cell Research2018，28，11： | 3 |
| 9 | Research on the Development of China’s International Cooperation Parks Along the Belt and Road: Status Quo, Effect, and Trend显示文摘This paper predicts the future development trend of China’s International Cooperation Parks(ICPs) along the Belt and Road by systematically summarizing the current situation and the effect they exert.Relevant research shows that these ICPs have not only promoted China’s industrial capacity cooperation and international industrial transfer, but also contributed to resource sharing between China and the countries along the Belt and Road.In addition, the ICPs play a positive role in further advancing social development of host countries and bilateral cooperation.Research also indicates that the development of ICPs, influenced by both a Chinese domestic 'pushing force' and a foreign 'pulling force,' is a result jointly produced by political, economic, diplomatic, and cultural factors.As ICPs are built in increasingly more countries along the Belt and Road and their leading industries tend to be more diverse, the environment and infrastructure in host countries would be improved and the importance of Chinese private enterprises would be further enhanced.In addition, ICPs will also further promote the development of local industrial parks.What should also be noted is that problems like an unbalanced layout, irrational planning, and lack of planning standards still exist in the ICPs, thus solutions and strategies for resolving these problems are proposed in the paper. | Zhao Shengbo Wang Xingping Hu Xuefeng Li Min(译) | 2019 | China City Planning Review2019，28，2： | 2 |
| 10 | Real-time energy optimization of HEVs under-connected environment: a benchmark problem and receding horizon-based solution显示文摘In this paper,we propose a benchmark problem for the challengers aiming to energy efficiency control of hybrid electric vehicles(HEVs)on a road with slope.Moreover,it is assumed that the targeted HEVs are in the connected environment with the obtainment of real-time information of vehicle-to-everything(V2X),including geographic information,vehicle-to-infrastructure(V2I)information and vehicle-to-vehicle(V2V)information.The provided simulator consists of an industrial-level HEV model and a traffic scenario database obtained through a commercial traffic simulator,where the running route is generated based on real-world data with slope and intersection position.The benchmark problem to be solved is the HEVs powertrain control using traffic information to fulfill fuel economy improvement while satisfying the constraints of driving safety and travel time.To show the HEV powertrain characteristics,a case study is given with the speed planning and energy management strategy. | Fuguo Xu Hiroki Tsunogawa Junichi Kako Xiaosong Hu Shengbo Eben Li Tielong Shen Lars Eriksson Carlos Guardiola | 2022 | Control Theory and Technology2022，20，2： | 2 |
| 11 | A framework for rapid on-board deterministic estimation of occupant injury risk in motor vehicle crashes with quantitative uncertainty evaluation显示文摘Accurate on-board occupant injury risk prediction of motor vehicle crashes(MVCs)can decrease fatality rates by providing critical information timely and improving injury severity triage rates.The present implemented prediction algorithms in vehicle safety systems are probabilistic and rely on multi-variate logistic regression of real-world vehicle collision databases.As a result,they do not utilize important vehicle and occupant features and tend to overgeneralize the solution space.This study presents a framework to address these problems with deterministic and computationally efficient lumped parameter model simulations driven by a database of vehicle crash tests.A 648-case mixed database was generated with finite element and multi-body models and validated under the principal directions of impact with experimental results for a single vehicle body type.Using the finite element database,we developed lumped parameter models for four principal modes of impact(i.e.,frontal,rear,near side and far side)with parameters identified via genetic algorithm optimization.To obtain confidence bounds for the injury risk prediction,the parameter uncertainty and model adequacy were evaluated with arbitrary and bootstrapped polynomial chaos expansion.The developed algorithm was able to achieve over triage rates of 17.1%±8.5%,whilst keeping the under triage rates below 8%on a finite element-multi body model database of a single vehicle body type.This study demonstrated the feasibility and importance of using low-complexity deterministic models with uncertainty quantification in enhanced occupant injury risk prediction.Further research is required to evaluate the effectiveness of this framework under a wide range of vehicle types.With the flexibility of parameter adjustment and high computational efficiency,the present framework is generic in nature so as to maximize future applicability in improved on-board triage decision making in active safety systems. | BANCE Iason YANG SaiChao ZHOU Qing LI ShengBo NIE BingBing | 2021 | Science China(Technological Sciences)2021，64，3： | 2 |
| 12 | PD1^+CCR2^+CD8^+T Cells Infiltrate the Central Nervous System during Acute Japanese Encephalitis Virus Infection显示文摘Japanese encephalitis(JE)is a viral encephalitis disease caused by Japanese encephalitis virus(JEV)infection.Uncontrolled inflammatory responses in the central nervous system(CNS)are a hallmark of severe JE.Although the CCR2-CCL2 axis is important for monocytes trafficking during JEV infection,little is known about its role in CNS trafficking of CD8^+T cells.Here,we characterized a mouse model of JEV infection,induced via intravenous injection(i.v.)and delineated the chemokines and infiltrating peripheral immune cells in the brains of infected mice.The CNS expression of chemokines,Ccl2,Ccl3,and Ccl5,and their receptors,Ccr2 or Ccr5.was significantly up-regulated after JEV infection and was associated with the degree of JE pathogenesis.Moreover,JEV infection resulted in the migration of a large number of CD8^+T cells into the CNS.In the brains of JEV-infected mice,infiltrating CD8^+T cells expressed CCR2 and CCR5 and were found to comprise mainly effector T cells(CD44^+CD62L_).JEV infection dramatically enhanced the expression of programmed death 1(PD-1)on infiltrating CD8^+T cells in the brain,as compared to that on peripheral CD8^+T cells in the spleen.This effect was more pronounced on infiltrating CCR2^+CD8^+T cells than on CCR2-CD8^+T cells.In conclusion,we identified a new subset of CD8^+T cells(PD1^+CCR2^+CD8^+T cells)present in the CNS of mice during acute JEV infection.These CD8^+T cells might play a role in JE pathogenesis. | Fang Zhang Linlin Qi Tong Li Xiaojing Li Dan Yang Shengbo Cao Jing Ye Bin Wei | 2019 | Virologica Sinica2019，34，5： | 2 |
| 13 | Mesenchymal stem cells loaded on 3D-printed gradient poly(e-caprolactone)/methacrylated alginate composite scaffolds for cartilage tissue engineering显示文摘Cartilage has limited self-repair ability due to its avascular,alymphatic and aneural features.The combination of three-dimensional(3D)printing and tissue engineering provides an up-and-coming approach to address this issue.Here,we designed and fabricated a tri-layered(superficial layer(SL),middle layer(ML)and deep layer(DL))stratified scaffold,inspired by the architecture of collagen fibers in native cartilage tissue.The scaffold was composed of 3D printed depth-dependent gradient poly(e-caprolactone)(PCL)impregnated with methacrylated alginate(ALMA),and its morphological analysis and mechanical properties were tested.To prove the feasibility of the composite scaffolds for cartilage regeneration,the viability,proliferation,collagen deposition and chondrogenic differentiation of embedded rat bone marrow mesenchymal stem cells(BMSCs)in the scaffolds were assessed by Live/dead assay,CCK-8,DNA content,cell morphology,immunofluorescence and real-time reverse transcription polymerase chain reaction.BMSCs-loaded gradient PCL/ALMA scaffolds showed excellent cell survival,cell proliferation,cell morphology,collagen II deposition and hopeful chondrogenic differentiation compared with three individual-layer scaffolds.Hence,our study demonstrates the potential use of the gradient PCL/ALMA construct for enhanced cartilage tissue engineering. | Yanyan Cao Peng Cheng Shengbo Sang Chuan Xiang Yang An Xiaochun Wei Zhizhong Shen Yixia Zhang Pengcui Li | 2021 | Regenerative Biomaterials2021，8，3： | 2 |
| 14 | Spatio-temporal Characteristics of Area Coverage and Observation Geometry of the MISR Land-surface BRF Product: A Case Study of the Central Part of Northeast Asia显示文摘The Multi-angle imaging spectroradiometer(MISR) land-surface(LS) bidirectional reflectance factor(BRF) product(MILS_BRF) has unique semi-simultaneous multi-angle sampling and global coverage. However, unlike on-satellite observations, the spatio-temporal characteristics of MILS_BRF data have rarely been explicitly and comprehensively analysed. Results from 5-yr(2011–2015) of MILS_BRF dataset from a typical region in central Northeast Asia as the study area showed that the monthly area coverage as well as MILS_BRF data quantity varies significantly, from the highest in October(99.05%) through median in June/July(78.09%/75.21%) to lowest in January(18.97%), and a large data-vacant area exists in the study area during four consecutive winter months(December through March). The data-vacant area is mainly composed of crop lands and cropland/natural vegetation mosaic. The amount of data within the principal plane(PP)±30°(nPP) or cross PP ±30°(nCP), varies intra-annually with significant differences from different view zeniths or forward/backward scattering directions. For example, multiple off-nadir cameras have nPP but no nCP data for up to six months(September through February), with the opposite occurring in June and July. This study provides explicit and comprehensive information about the spatio-temporal characteristics of product coverage and observation geometry of MILS_BRF in the study area. Results provide required user reference information for MILS_BRF to evaluate performance of BRDF models or to compare with other satellite-derived BRF or albedo products. Comparing this final product to on-satellite observations, what was found here reveals a new perspective on product spatial coverage and observation geometry for multi-angle remote sensing. | LI Jian CHEN Shengbo QIN Wenhan Mike MUREFU WANG Yufei YU Yan ZHEN Zhijun | 2019 | Chinese Geographical Science2019，29，4： | 1 |
| 15 | Battery for electrified vehicles显示文摘 | HU Xiaosong Shengbo Eben Li Zhenzhong Jia | 2014 | Energy2014，，： | 1 |
| 16 | Inhibition of porcine circovirus type 1 and type 2 production in PK-15 cells by small interfering RNAs targeting the Rep gene显示文摘 | Minxuan Sun Xueqin Liu Shengbo Cao Qigai He Rui Zhou Jing Ye Yaoming Li Huanchun Chen | 2007 | Veterinary Microbiology2007，，1： | 1 |
| 17 | Acta Physica Sinica显示文摘 | Li Shengbo Yan Hui Jiang Hongyuan | 2012 | 61(1): 010 7022012，61，01： | 1 |
| 18 | Model predictive multi-objective vehicular adaptive cruise control 显示文摘 | LI Shengbo LI Keqiang Rajamani R | 2011 | IEEE Transactions on Control Systems Technology2011，19，3： | 1 |
| 19 | A comparative study of equivalent circuit models for Li-ion batteries显示文摘 | Hu Xiaosong Li Shengbo Peng H | 2012 | Journal of Power Sources2012，，198： | 1 |
| 20 | Model predictive multi-objective vehicular adaptive cruise control 显示文摘 | LI Shengbo LI Keqiang RAJAMANI Rajesh | 2011 | IEEE Trans Contr Syst Tech2011，19，3： | 1 |
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