|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Treatment of Hepatitis C Virus Infection Among People Who Are Actively Injecting Drugs: A Systematic Review and Meta-analysis显示文摘 | Esther J. Aspinall Stephen Corson Joseph S. Doyle Jason Grebely Sharon J. Hutchinson Gregory J. Dore David J. Goldberg Margaret E. Hellard | 2013 | Clinical Infectious Diseases (suppl )2013，，2： | 1 |
| 2 | Alpha-Synuclein occurs in lipid-rich high molecular weight complexes,binds fatty acids,and shows homology to the fatty acid-binding proteins显示文摘 | Sharon R Goldberg MS Bar-Josef I | 2001 | Proc Natl Acad Sci U S A2001，98，： | 1 |
| 3 | Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy显示文摘 | Natasha K. Martin Matthew Hickman Sharon J. Hutchinson David J. Goldberg Peter Vickerman | 2013 | Clinical Infectious Diseases . 2013 (supp)2013，，： | 1 |
| 4 | Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy显示文摘 | Natasha K. Martin Matthew Hickman Sharon J. Hutchinson David J. Goldberg Peter Vickerman | 2013 | Clinical Infectious Diseases (suppl )2013，，2： | 1 |
| 5 | Detection of hepatitis C virus RNA in dried blood spots显示文摘 | Susan Bennett Rory N. Gunson Georgina E. McAllister Sharon J. Hutchinson David J. Goldberg Sheila O. Cameron William F. Carman | 2012 | Journal of Clinical Virology2012，，2： | 1 |
| 6 | Treatment of Hepatitis C Virus Infection Among People Who Are Actively Injecting Drugs: A Systematic Review and Meta-analysis显示文摘 | Esther J. Aspinall Stephen Corson Joseph S. Doyle Jason Grebely Sharon J. Hutchinson Gregory J. Dore David J. Goldberg Margaret E. Hellard | 2013 | 2013 (supp)2013，，： | 1 |
| 7 | Efficient serial messagepassing schedules for LDPC decoding显示文摘 | SHARON E LITSYN S GOLDBERGER J | 2007 | IEEE Trans Inform Theory2007，53，11： | 1 |
| 8 | Efficient Serial Message-Passing Schedules for LDPC Decoding显示文摘 | Sharon E Litsyn S Goldberger J | 2007 | IEEE Trans on Inform Theory2007，53，11： | 1 |
| 9 | Treatment of Hepatitis C Virus Infection Among People Who Are Actively Injecting Drugs: A Systematic Review and Meta-analysis显示文摘 | Esther J. Aspinall Stephen Corson Joseph S. Doyle Jason Grebely Sharon J. Hutchinson Gregory J. Dore David J. Goldberg Margaret E. Hellard | 2013 | Clinical Infectious Diseases (suppl )2013，，2： | 1 |
| 10 | Can antiviral therapy for hepatitis C reduce the prevalence of HCV among injecting drug user populations? A modeling analysis of its prevention utility显示文摘 | Natasha K. Martin Peter Vickerman Graham R. Foster Sharon J. Hutchinson David J. Goldberg Matthew Hickman | 2010 | Journal of Hepatology2010，，6： | 1 |
| 11 | Efficient seria message-passing schedules for LDPC decoding显示文摘 | Sharon E Litsyn S Goldberger J | 2007 | IEEE Trans on Inf Theory2007，53，11： | 1 |
| 12 | alpha-Syn occurs in lipid-rich high molecular weight complexES, binds fatty acid ,and shows homology to the fatty acids-binding proteins 显示文摘 | Goldberg MS Bar-Josef I | 2001 | Proc Natl Acad Sci USA2001，98，： | 1 |
| 13 | Uptake of hepatitis C specialist services and treatment following diagnosis by dried blood spot in Scotland显示文摘 | Georgina McAllister Hamish Innes Allan Mcleod John F. Dillon Peter C. Hayes Ray Fox Stephen T. Barclay Kate Templeton Celia Aitken Rory Gunson David Goldberg Sharon J. Hutchinson | 2014 | Journal of Clinical Virology2014，，： | 1 |
| 14 | Hotspot of Adult Cuban Treefrog and Cane Toad Multi-organ Abnormality in Suburban South-west Florida显示文摘This study represents a continuation of the Florida hotspot of tadpole abnormality found in the Southwest Florida suburban roadside drainage ditches in 2012 to determine if the adult frogs and toads frequenting the study sites were anatomically abnormal.The gross examination of all organs included 397 adult anurans and 40 metamorphs representing five anuran species:Osteopilus septentrionalis(N=364),Rhinella marina(N=60),Lithobates sphenocephala(N=7),Anaxyrus terrestris(N=5)and Anaxyrus americanus(N=1).The gonads,liver,kidney and intestines were abnormal at a frequency of 87.4%.The few normal anurans(12.6%)were females and young male adults.We found a significant difference in organ abnormality type and f requency between sexes.Almost all f rog and toad males had testicular abnormality(92%)with only 6%with normal testes,whereas the female gonad abnormality was lower,at 41.6%.Hermaphroditism was found in both sexes at a frequency of 26.2%.The toads had a significantly higher frequency of hermaphroditism than the frogs.The toad hermaphroditism frequency was found to be 40%,whereas the frog hermaphroditism 23.3%.A hermaphrodite Cane toad male with a female phenotype coexisted with the normal male phenotype hermaphrodite.The fertility of 27 in situ pairs was assessed.The fertile testicular abnormal male and hermaphrodite pairs produced offspring with abnormal larval morphology.This information adds new evidence of the effect of chemicals on wild populations and the effect on non-target species which has always been underestimated. | Sharon Pratt ANZALDUA Javier GOLDBERG | 2020 | Asian Herpetological Research2020，11，2： | 0 |
| 15 | Intravenous infusion of magnesium sulfate is not associated with cardiovascular,liver,kidney,and metabolic toxicity in adults显示文摘Background:Magnesium(Mg)deficiency contributes to the pathophysiology of numerous diseases.The therapeutic use of Mg has steadily increased over time.The increased in-hospital use of intravenous(IV)magnesium sulfate(MgSO4)warrants more extensive investigation regarding the safety of the therapy.The aim of this study was to determine the safety of IV MgSO4 infusion on cardiovascular,liver,kidney,and metabolic markers in adults.Methods:Twelve volunteers were randomized to one of two cross-over conditions:(a)IV infusion of MgSO4 in 5%dextrose followed by IV infusion of 5%dextrose 1 week later or(b)IV infusion of 5%dextrose followed by IV infusion of MgSO4 in 5%dextrose 1 week later.An electrocardiogram was recorded continuously during the infusions.Blood was drawn pre-and post-infusion for blood count(high-density lipoprotein cholesterol,low-density lipoprotein cholesterol,and triglycerides).Results:Serum Mg increased from pre-to post-infusion in the MgSO4+5%dextrose group(p<0.0001).The QRS interval length increased from pre-to post-infusion in the MgSO4+5%dextrose group(p<0.04).Additionally,serum glucose concentration increased in the MgSO4+5%dextrose group(p=0.04).These significant findings were modeled with gender and age as covariates.No other significant differences were found.Conclusions:The administration of IV infusion of MgSO4(4 g/100 mL)in 5%dextrose over a 4-hour treatment period poses no significant deleterious effects on cardiovascular,liver,kidney,or metabolic function.Relevance for patients:IV infusion of MgSO4 may be used for certain treatment indications without significant concern for systemic or organ toxicity. | Elisa Karhu Steven E.Atlas Jinrun Gao Syed A.Mehdi Dominique Musselman Sharon Goldberg Judi M.Woolger Raul Corredor Muhammad H.Abbas Leopoldo Arosemena Simone Caccamo Ashar Farooqi Janet Konefal Laura Lantigua Vanessa Padilla Ammar Rasul Eduard Tiozzo Oscar L.Higuera Andrea Fiallo John E.Lewis | 2018 | Journal of Clinical & Translational Research2018，4，1： | 0 |
| 16 | Anti-cancer effects of aloe-emodin:a systematic review显示文摘Background:Anthraquinones are a possible treatment option for oncological patients due to their anti-cancer properties.Cancer patients often exhaust a plethora of resources that ultimately fail to provide fully curative measures.Alternative treatments are subsequently sought in the hope of finding a therapeutic remedy.Potential regimens include aloe-emodin and its related derivatives.This review therefore summarizes the effects of aloe-emodin and other aloe components in light of their anti-proliferative and anti-carcinogenic properties.Methods:A systematic search was performed in PubMed for aloe-emodin and cancer in humans.Sixty abstracts of in vitro studies were selected and reviewed with subsequent screening of the full text.Thirty-eight articles were summarized.Results:Aloe-emodin possesses multiple anti-proliferative and anti-carcinogenic properties in a host of human cancer cell lines,with often multiple vital pathways affected by the same molecule.The most notable effects include inhibition of cell proliferation,migration,and invasion;cycle arrest;induction of cell death;mitochondrial membrane and redox perturbations;and modulation of immune signaling.The effects of aloe-emodin are not ubiquitous across all cell lines but depend on cell type.Conclusions:On the basis of this systematic review,the multiple consistent effects of aloe-emodin in human-derived cancer cell lines suggest that aloe-emodin is a potential anti-cancer agent that acts on cancer cells in a pleiotropic manner.Relevance for patients:Cancer patients often utilize alternative therapies as a result of suboptimal efficacy of conventional treatments.Aloe-emodin might become a therapeutic option for cancer patients if the basic research is confirmed in clinical trials. | Brian Sanders Anna M.Ray Sharon Goldberg Tyler Clark H.Reginald McDaniel Steven E.Atlas Ashar Farooqi Janet Konefal Lucas C.Lages Johanna Lopez Ammar Rasul Eduard Tiozzo Judi M.Woolger John E.Lewis | 2017 | Journal of Clinical & Translational Research2017，3，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员