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275篇 您的检索式:作者名="Shannon K"
    题名 作者 年代 出处 被引量
1Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease显示文摘Mitochondrial dysfunction is known to be a contributing factor to a number of diseases including chronic alcohol induced liver injury. While there is a detailed understanding of the metabolic pathways and proteins of the liver mitochondrion, little is known regarding how changes in the mitochondrial proteome may contribute to the development of hepatic pathologies. Emerging evidence indicates that reactive oxygen and nitrogen species disrupt mitochondrial function through post-translational modifications to the mitochondrial proteome. Indeed, various new affinity labeling reagents are available to test the hypothesis that post-translational modification of proteins by reactive species contributes to mitochondrial dysfunction and alcoholic fatty liver disease. Specialized proteomic techniques are also now available, which allow for identification of defects in the assembly of multi-protein complexes in mitochondria and the resolution of the highly hydrophobic proteins of the inner membrane. In this review knowledge gained from the study of changes to the mitochondrial proteome in alcoholic hepatotoxicity will be described and placed into a mechanistic framework to increase understanding of the role of mitochondrial dysfunction in liver disease.Sudheer K Mantena Adrienne L King Kelly K Andringa Aimee Landar Victor Darley-Usmar Shannon M Bailey 2007World Journal of Gastroenterology2007,13,37:7
2Alterations in left ventricular diastolic function in conscious dogs with pacing-induced heart failure显示文摘Komamura K Shannon RP Pasipoularides A 1992J Clin Invest1992,89,:1
3Reasons fornon randomization in the UK3 trial of surgical app roach in localizedWilms' tumour requiting a difficult day one randomization:a UKCCSGWilms' Tumour Group study显示文摘Pritchard-Jones K Mitchell C Shannon R 2003Med Pediatr Oncol2003,41,:1
4In the series analytic: Biosynthesis and molecular regulation of amino acids in plants 显示文摘Singh B K Flores H E Shannon J C 1992American Society of Plant Physiologists : Rockville MD1992,,:1
5Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1显示文摘Balaji K Shannon BD Brian K 2003Cancer Res2003,63,:1
6Hyperactive Ras as a therapeutic target in neurofibromatosis type 1 显示文摘Weiss B Bollag G Shannon K 1999Am J Med Genet1999,89,1:1
7Hyperactive Ras as a therapeutic target in neurofibromatosis type 1 显示文摘Weiss B Bollag G Shannon K 1999Am J Med Genet1999,89,1:1
8Theory of mind function, motor empathy, emotional empathy and schizophrenia: A single case study显示文摘Addy K Shannon K Brookfield K 2007Journal of Forensic Psychiatry and Psychology2007,,3:1
9Nucleotides and nucleotide sugars in developing maize endosperms (synthesis of ADP-glucose in brittle-1)显示文摘 F M Pien K C Liuet Pien F M Liu K C 1996Plant Physiol1996,110,:1
10Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol - and obesity - induced fatty liver diseases 显示文摘Mantena Sudheer K King Adrienne L Andringa Kelly K Ec- cleston Heather B Bailey Shannon M 2008Free radical biology & medi- cine2008,44,7:1
11Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication显示文摘Renate K?nig Yingyao Zhou Daniel Elleder Tracy L. Diamond Ghislain M.C. Bonamy Jeffrey T. Irelan Chih-yuan Chiang Buu P. Tu Paul D. De Jesus Caroline E. Lilley Shannon Seidel Amanda M. Opaluch Jeremy S. Caldwell Matthew D. Weitzman Kelli L. Kuhen Sourav B 2008Cell2008,,1:1
12Brittle-1,an adenylate translocator,facilitates transfer of extraplastidial synthesized ADP-Glucose into amyloplasts of maize endosperms显示文摘 Pien F M Cao H P Liu K C 1998Plant Physiol1998,117,:1
13DNA sequence differences of ampD mutants of Citrobacter freundii显示文摘 Shannon K Phillips I 1995Antimicrob Agents Chemother1995,39,11:1
14Preparation and properties of water-soluble poly(styrenesulfonic acid)-doped polyaniline 显示文摘Shannon K Fernandez J E 1994J Chem Soc Chem Commun1994,5,:1
15Regulation of colon carcinoma cell invasion by hypoxia-inducible factor-l显示文摘BALAJI K SHANNON B D BRAIN K 2003CancerRes2003,63,:1
16Polyaspartatc scale inhibitors biodegrasable alternative to polyacrylate 显示文摘Ross R J Low K C Shannon J E 1997Materials Performance1997,36,4:1
17Interpretative reading recognizing the unusual and inferring resistance mechanisms from resistance phe7 notypes 显示文摘LIVEMORE D M WlNSTANLEY T G SHANNON K P 2001J Antimicrob Chemother2001,48,1:1
18Locating Ambulatory Medical Care Facilities for the Elderly 显示文摘Cromley E K Shannon G W 1986Health Services Research1986,21,4:1
19Unrearaed intrarnedullary nail versus external fixation in grade HI open tibial fractures 显示文摘Shannon FJ Mullett H ORourke K 2002J Trau- ma2002,52,4:1
20Development of definitive endoderm from embryonic stem cells in culture 显示文摘Kubo A Shinozaki K Shannon JM 2004Development2004,131,7:1
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