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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | The predictive value of triglyceride-glucose index for in-hospital and one-year mortality in elderly non-diabetic patients with ST-segment elevation myocardial infarction显示文摘BACKGROUND Triglyceride-glucose(TyG)index,a reliable marker of insulin resistance,was associated with cardiovascular morbidity and mortality.This study aimed to evaluate the predictive value of TyG index for mortality in elderly non-diabetic pa-tients with ST-segment elevation myocardial infarction(STEMI).METHODS In total,430 non-diabetic patients aged over 65 years with STEMI were consecutively included.The TyG index was calculated by using the following formula:TyG index=ln(fasting triglyceride×fasting glucose/2).The 5-item modified frailty index score was utilized to determine comorbidities.Patients were divided into three groups based on TyG index tertiles.RESULTS Patients included into high TyG index tertile were male and had higher body mass index,glucose,triglyceride,low-density lipoprotein cholesterol,5-item modified frailty index and GRACE risk score;and had low systolic blood pressure,estim-ated glomerular filtration rate and left ventricular ejection fraction.A one-unit increase in TyG index was associated with 3.03 ex-tra cases per 1000 person-day for in-hospital mortality and 0.29 extra cases per 1000 person-day for long-term mortality.There was a non-linear relationship between TyG index and the risk of mortality with an increased risk above 8.5 for TyG index.Kaplan-Meier survival curves revealed that patients in high TyG index tertile had higher in-hospital and long-term mortality rates than those in low TyG index tertile.CONCLUSIONS This was the first study to demonstrate that the TyG index could predict in-hospital and long-term mortality in elderly non-diabetic STEMI patients. | FaysalŞaylık TufanÇınar Murat Selçuk İbrahim Halil Tanboğa | 2022 | Journal of Geriatric Cardiology2022，19，8： | 3 |
| 3 | Carbon content influ- ence on the optical constants of hydrogenated amorphous sil- icon carbon alloys 显示文摘 | Akaoglu B Sel K Atilgan I | 2008 | Optical Materials2008，30，8： | 1 |
| 4 | Efficient hydrolytic hydrogenation of cellulose in the presence of Ru-loaded zeolites and trace amounts of mineral acid显示文摘 | GEBOERS J VAN DE VYVER S CARPENTIER K JACOBS P SELS B | 2011 | Catal Commun2011，47，19： | 1 |
| 5 | Ecological consequences of the phylogenetic and physiological diversities of acetogens显示文摘 | Harold L. Drake Kirsten Küsel Carola Matthies | 2002 | Antonie van Leeuwenhoek (-)2002，，1： | 1 |
| 6 | Development of a risk tool for deliberate self-extubation in intensive care patients显示文摘 | Moons P Sels K De Becker W | 2004 | Intensive Care Med2004，30，7： | 1 |
| 7 | Development of a risk assessment tool for deliberate self-extubation in intensive care patients显示文摘 | Moons P Sels K De Becker W | | 0，，07： | 1 |
| 8 | Monitoring of an Aeroponic Greenhouse with a Sensor Network显示文摘 | Leong B T Chan T K Sel appan P | | 0，，3： | 1 |
| 9 | Development of a risk assess- ment tool for deliberate self-extuhation in intensive care patients 显示文摘 | Moons P Sels K DeBecker W | 2004 | Intensive Care Med2004，30，7： | 1 |
| 10 | Non-alcoholic steatohepatitis:review of a growing medical problem显示文摘 | TE SLIGTE K BOURASS I SELS J P | 2004 | Eur J Intern Med2004，15，： | 1 |
| 11 | Development of a risk tool for deliberate self-extubation in intensive care patients显示文摘 | Moons P Sels K Becker W ct al | 2004 | Intensive care medicine2004，30，7： | 1 |
| 12 | Non-alcoholic steatohepatitis:review of growing medical problem 显示文摘 | Teslighte K Bourass I Sels JP | 2004 | Eur J Intern Med2004，15，1： | 1 |
| 13 | Development of a risk tool for deliberate self-extubation in intensive care patients显示文摘 | Moons P Sels K De Becker W | 2004 | Intensive Care Medicine2004，30，7： | 1 |
| 14 | Development of a risk assessment tool fol Deliberate self-extubation in intensive care patients显示文摘 | Moons P Sels K De Becker W | 2004 | Intensive Care Med2004，30，7： | 1 |
| 15 | Development of a risk tool for deliberate self- extubation in intensive carepatients显示文摘 | Moons P Sels K De Becket W | 2004 | Inten- sive Care Med2004，30，7： | 1 |
| 16 | Development of a risk tool for deliberate self--extubation in internsive care patients 显示文摘 | Moons P Sels K De Becker W | 2004 | Intensive care medicine2004，30，： | 1 |
| 17 | Development of a risk tool for deliberate self- extubation in intensive care patients 显示文摘 | Moons P Sels K De Becker W | 2004 | Intensive Care Med2004，30，7： | 1 |
| 18 | Non-alcoholic steatohepatitis:review of a growing medical problem显示文摘 | Sligte K Bourass I Sels JP | 2004 | Eur J Intern Med2004，15，： | 1 |
| 19 | Detection of relative and levels in sweat with optical measurements 显示文摘 | Al-omaril M Sel K Mueller A | 2014 | J Appl Phys2014，115，20： | 1 |
| 20 | Reasoning for Web Document Associations and Its Applications in Site Map Construction显示文摘 | Sel?uk K Li Wen-Syan | 2002 | Data & Knowledge Engineering2002，43，2： | 1 |
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