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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection显示文摘 | Luca Formichella Laura Romberg Christian Bolz Michael Vieth Michael Geppert Gereon G?ttner Christina N?lting Dirk Walter Wolfgang Schepp Arne Schneider Kurt Ulm Petra Wolf Dirk H. Busch Erwin Soutschek Markus Gerhard | 2013 | Clinical and Vaccine Immunology2013，，11： | 2 |
| 3 | Corrigendum to “Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis” [Cancer Lett. 328 (2) (2012) 212–221]显示文摘 | Angela L. McCleary-Wheeler Gwen A. Lomberk Frank U. Weiss Günter Schneider Muller Fabbri Tara L. Poshusta Nelson J. Dusetti Sandra Baumgart Juan L. Iovanna Volker Ellenrieder Raul Urrutia Martin E. Fernandez-Zapico | 2013 | Cancer Letters2013，，1： | 2 |
| 4 | La_(0.7)Sr_(0.3)MnO_3-Pb(Zr,Ti)O_3双层膜中的磁电(ME)效应显示文摘由溶胶-凝胶法制备出锰酸盐La0.7Sr0.3MnO3粉料,经1300K热压并在1573K高温下烧结成块材,并与Pb(Zr,Ti)O3胶合形成弹性耦合双层膜。相较于涂敷膜(tape casting)复合样品,该双层膜显示出更为优良的ME耦合效应。横向耦合要比纵向耦合更为强烈,并当外加磁场为150 Oe时ME电压系数达到峰值。分析表明由磁场和频率变化导致的ME系数变化的实验值与理论值符合的很好。 | 张宁 印晓明 张茹 范军峰 王淼 Yang W Schneider T Srinivasan G | 2006 | 功能材料与器件学报2006，12，4： | 2 |
| 5 | Experimental Separation of Rashba and Dresselhaus Spin - Splittings in Semiconductor Quantum Wells 显示文摘 | Ganichev S D Bel'kov V V GoRlub L E Ivchenko E L Schneider P Giglberger S Eroms J DeBoeck J Borghs G Wegscheider W Weiss D Prettl W | | cond0，，： | 1 |
| 6 | Esmolol potentiates reduction of minimum alveolar isoflurane concentration by alfentanil显示文摘 | JOHANSEN JW SCHNEIDER G WINDSOR AM | 1998 | Anesth Analg1998，87，1： | 1 |
| 7 | Time delay of index caculation:analysis of cerebral state,bispectral,and narcotrend indices显示文摘 | Pilge S Zanner R Schneider G | 2006 | Anesthesiology2006，104，48： | 1 |
| 8 | Sizing of MOS transistors for amplifier design显示文摘 | Pinto R L D Schneider M C Montoro C G | 2002 | IEEE International Symposium on Circuits and Systems2002，5，： | 1 |
| 9 | Bcl-2 promotes regeneration of severed axons in mammalian CNS显示文摘 | Schneider G Martinon J | 1997 | Nature1997，385，： | 1 |
| 10 | Elevated focal adhesion kinase expression facilitates oral tumor cell invasion显示文摘 | Schneider G B Kurago Z Zaharias R | 2002 | Cancer2002，95，12： | 1 |
| 11 | The syndrome of acute central cervical spinal cord injury:with special reference to the mechanisms involved in haperextension injuries of cervical spine显示文摘 | Schneider RC Cherry G Pantek H | 1954 | J Neurosurg1954，11，5： | 1 |
| 12 | Simplifying single-stage solid abutments: techniques for impressioning and temporization 显示文摘 | Schneider A L Kurtzman G M | 2004 | Dent Today2004，23，10： | 1 |
| 13 | Formation of focal adhesions by osteoblasts adhering to different substrata显示文摘 | Schneider G Burridge K | 1994 | Exp Cell Res1994，214，1： | 1 |
| 14 | Sudden sensorineural hearing loss during oral anticoagulant therapy显示文摘 | Mierzwa K Schneider G Muller A | 2004 | Laryngol Otol2004，118，11： | 1 |
| 15 | Xylem water transport: is the available evidence consistent with the cohesion theory显示文摘 | ZIMMERMANN U MEINZER F C BENKERT R ZHU J J SCHNEIDER H GOLDSTEIN G KUCHENBROD E HAASE A | 1994 | Plant Cell Environ1994，17，： | 1 |
| 16 | Spurious precision? Meta-analysis of observational studies显示文摘 | Egger M Schneider M Davey-Smith G | 1998 | BMJ1998，316，： | 1 |
| 17 | Biasin meta-analysis deteceed byasimple,graphical test显示文摘 | EGGER M SMITH G D SCHNEIDER M | 1997 | BMJ1997，315，： | 1 |
| 18 | IL-18 Stimulates the proliferation and IFN-γ release of CD4^+ T cells in the chicken: conservation of a Th1-Like system in a noumamalian Species 显示文摘 | Thomas W G Schneider K Schacear B | 2003 | Immunol2003，171，： | 1 |
| 19 | Efficacy of computerassited surgery in secondary orbital reconstruction显示文摘 | LAUER G PRADEL W SCHNEIDER M | 2006 | J Craniomaxillofac Surg2006，34，5： | 1 |
| 20 | RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions显示文摘 | Collins B J Chiappetta G Schneider A | 2002 | J Clin Endocrinol Metab2002，87，8： | 1 |
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