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| 1 | Expression of the B7 - related molecule B7 - H1 by glioma cells: a potential mechanism of immune paralysis显示文摘Human glioblastoma is a highly lethal tumor that is known for its immune inhibitory capabilities.B7-homologue l(B7-H 1),a recently identified homologue of B7.1/2(CD80/86),has been described to exert costimulatoryand immune regulatory functions.We investigated the expression and the functional activity of B7-H 1 in humanglioma cells in vitro and in vivo.Although lacking B7.1/2(CD80/86),all 12 glioma cel1 1ines constitutivelyexpressed B7-H1 mRNA and protein.Exposure to IFN-gamma strongly enhanced B7-H 1 expression.Im- | Wintterle S Schreiner B Mitsdoerffer M Schneider D Chen Meyermann R Weller M Wiendl H | 2003 | 中国神经肿瘤杂志2003,1,4: | 37 |
| 2 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014,11,3: | 31 |
| 3 | The Sandfish's Skin:Morphology,Chemistry and Reconstruction显示文摘The sandfish is a lizard having the remarkable ability to move in desert sand in a swimming-like fashion. The most out-standing adaptations to this mode of life are the low friction behaviour and the extensive abrasion resistance of the sandfish skin against sand, outperforming even steel. We investigated the topography, the composition and the mechanical properties of sandfish scales. These consist of glycosylated keratins with high amount of sulphur but no hard inorganic material, such as silicates or lime. Remarkably, atomic force microscopy shows an almost complete absence of attractive forces between the scale surface and a silicon tip, suggesting that this is responsible for the unusual tribological properties. The unusual glycosylation of the keratins was found to be absolutely necessary for the described phenomenon. The scales were dissolved and reconstituted on a polymer surface resulting in properties similar to the original scale. Thus, we provide a pathway towards exploitation of the reconstituted scale material for future engineering applications. | Werner Baumgartner Friederike Saxe Agnes Weth David Hajas Darwin Sigumonrong Jens Emmerlich Martin Singheiser Wolfgang Bhme Jochen M. Schneider | 2007 | Journal of Bionic Engineering2007,4,1: | 10 |
| 4 | Anaplastic pancreatic cancer: Presentation, surgical management, and outcome显示文摘 | Oliver Strobel Werner Hartwig Frank Bergmann Ulf Hinz Thilo Hackert Lars Grenacher Lutz Schneider Stefan Fritz Matthias M. Gaida Markus W. Büchler Jens Werner | 2011 | Surgery2011,,2: | 2 |
| 5 | Bacterial translocation and infected pancreatic necrosis in acute necrotizing pancreatitis derives from small bowel rather than from colon显示文摘 | Stefan Fritz Thilo Hackert Werner Hartwig Florian Rossmanith Oliver Strobel Lutz Schneider Katja Will-Schweiger Mechthild Kommerell Markus W. Büchler Jens Werner | 2010 | The American Journal of Surgery2010,,1: | 2 |
| 6 | CMR Imaging Predicts Death and Other Adverse Events in Suspected Cardiac Sarcoidosis显示文摘 | Simon Greulich Claudia Christina Deluigi Steffen Gloekler Andreas Wahl Christine Zürn Ulrich Kramer Detlev Nothnagel Helmut Bültel Julia Schumm Stefan Grün Peter Ong Anja Wagner Steffen Schneider Kai Nassenstein Meinrad Gawaz Udo Sechtem Oliver Bruder Hei | 2013 | JACC: Cardiovascular Imaging2013,,: | 2 |
| 7 | Desiccation leads to the rapid accumulation of both cytosolie and chloroplastic proteins in the resurrection plant Craterostigma plantagineum Hochst显示文摘 | Schneider K Wells B Schmelzer E | 1993 | Planta1993,189,: | 1 |
| 8 | The meaning of employee engagement显示文摘 | Macey W H Schneider B | 2008 | Industrial and Organizational Psychology2008,1,1: | 1 |
| 9 | Related articles, links polymorphisms in MHC - DRA and - DRB alleles of water buf- falo ( Bubalus bubalis) reveal different features from cattle DR alleles 显示文摘 | SENA L SCHNEIDER M P BRENIG B | 2003 | Anim Genet2003,34,1: | 1 |
| 10 | Elevated focal adhesion kinase expression facilitates oral tumor cell invasion显示文摘 | Schneider G B Kurago Z Zaharias R | 2002 | Cancer2002,95,12: | 1 |
| 11 | Biogenesis of volatile aldehydes from fatty acid hydroperoxides:molecular cloning of a hydroperoxide lyase (CYP74C) with specificity for both the 9-and 13-hydroperoxides of linoleic and linolenic acids显示文摘 | TIJET N SCHNEIDER C MULLER B L | 2001 | Arch Biochem Biophys2001,386,: | 1 |
| 12 | The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts显示文摘 | Martin B Schneider R Janetzky S | 2002 | J Cell Biol2002,159,1: | 1 |
| 13 | The ASA framework: An update显示文摘 | Schneider B Goldstein H W and Smith D B | 1995 | Personnel Psychology1995,48,4: | 1 |
| 14 | The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'显示文摘 | Kube M Schneider B Kuhl H | 2008 | BMC Genomics2008,9,: | 1 |
| 15 | Neonatal complica- tions and risk factors among women with gestational diabetes mellitus 显示文摘 | Schneider S Hoeft B Freerksen N | 2011 | Acta Obstet Gynecol Scand2011,90,3: | 1 |
| 16 | Influence of age and gender on associations of body mass index with bone mineral density, bone turnover markers and circulating calci- um - regulating and bone - active sex hormones 显示文摘 | PUNTUS T SCHNEIDER B MERAN J | 2011 | Bone2011,49,4: | 1 |
| 17 | Investigation of renal lesions by diffusion-weighted magnetic resonance imaging applying intravoxel incoherent motion-derived parameters--initial experience 显示文摘 | Rheinheimer S Stieltjes B Schneider F | 2012 | Eur J Radiol2012,81,3: | 1 |
| 18 | IL-18 Stimulates the proliferation and IFN-γ release of CD4^+ T cells in the chicken: conservation of a Th1-Like system in a noumamalian Species 显示文摘 | Thomas W G Schneider K Schacear B | 2003 | Immunol2003,171,: | 1 |
| 19 | A Glucosinolate Metabolism Pathway in Living Plant Cells Mediates Broad-Spectrum Antifungal Defense 显示文摘 | Bednarek P Pislewska-Bednarek M Svatos A Schneider B Doubsky J | 2009 | Science2009,323,: | 1 |
| 20 | PKSP-dependent reduction of phagolysosome fusion and intracellular kill of Aspergillus fumigatus conidia by human monocyte-derived macrophages 显示文摘 | Jahn B Langfelder K Schneider U | 2002 | Cell Microbiol2002,4,12: | 1 |