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| 1 | The vital threat of an upper gastrointestinal bleeding: Risk factor analysis of 121 consecutive patients显示文摘瞄准:在预言死亡的病人风险由于分析重要性上面胃肠(UGI ) 在今天的治疗学的政体下面流血。方法:从 1998 ~ 2001,有 UGI 流血的诊断的 121 个病人在我们的医院里被对待。基于病人的数据,一回顾多变量数据分析与开始,超过 270 个单个因素被执行。随后,下列潜在的风险因素经历了逻辑回归分析:年龄,性,起始的血红素, coumarines ,肝肝硬化,前凝血酶时间(磅),胃溃疡(小弯曲),十二指肠溃疡(灯泡我们背墙),福雷斯特分类,脉管的树桩, variceal 流血, Mallory-Weiss 症候群, RBC 替换,周期性的流血,保守、外科的治疗。结果:七十男性(58%) 和 51 女性(42%) 有 70 的中部的年龄的病人(变化:21-96 ) 年被对待。他们的在里面医院死亡是 14% 。当(11/91 )12% 在保守治疗以后死于病人时,(6/30 )20% 在经历外科的治疗以后死了。流血的 UGI 由于十二指肠溃疡发生了(n = 36;30%) ,胃溃疡(n = 35;29%) ,食道的静脉曲张病(n = 12;10%) , Mallory-Weiss 症候群(n = 8;7%) ,粘膜的腐蚀损害(n = 20;17%) ,癌症(n = 5;4%) , coagulopathy (n = 4;3%) ,淋巴瘤(n = 2;2%) ,良性瘤(n = 2;2%) 并且未知理智(n = 1;1%) 。所有上述的因素的逻辑回归分析揭示了那肝肝硬化和十二指肠溃疡(灯泡我们背墙) 是为在 UGI 流血以后的一堂致命的功课的联系风险因素。在内视镜检查法以前,仅仅肝肝硬化是一个可估价的风险因素。此后,肝肝硬化,流血溃疡的地点(灯泡我们背墙) 并且病人的性(男性) 具有为有流血溃疡的病人的临床的结果(死亡) 的预示的重要性。结论:在今天的临床的常规使用的最预示的参数不在预言一个病人的重要威胁由流血的 UGI 摆姿势是足够可靠的。在另一方面,肝肝硬化更经常显著地与增加的风险被联系在在以后的十二指肠的墙定位的溃疡流血以后死。 | Peter Schemmer Frank Decker Genevieve Dei-Anane Volkmar Henschel Klaus Buhl Christian Herfarth Stefan Riedl | 2006 | World Journal of Gastroenterology2006，12，22： | 16 |
| 2 | 大鼠肾移植1000例经验总结显示文摘目的:对大鼠肾移植进行经验总结以指导实验与临床研究。方法:作者在2004-01/2009-07海德堡大学移植中心期间,采用大鼠肾动、静脉与腹主动脉、腔静脉行端侧吻合。对于急性肾移植模型,输尿管直接植入膀胱内;对于慢性肾移植模型,输尿管采用端端吻合法。术中直接切除对侧肾脏,完成大鼠肾移植1000例,并对其进行总结。结果:只要供体肾脏冲洗良好,吻合时暖缺血时间小于30min,手术时间60min左右,吻合技术娴熟,移植成功率达98%以上。结论:该实验模型安全、方便、可行。肾移植成功的关键是手术技术。 | 李占清 关晓海 王世军 陈晶 伊雪 邬鹏宇 肖志 Nickkholgh Arash Bruns Helge Hoffmann Katrin Schemmer Peter | 2011 | 中国组织工程研究与临床康复2011，15，5： | 7 |
| 3 | Ischemia/Reperfusion Injury in Liver Surgery and Transplantation: Pathophysiology显示文摘 | Kilian Weigand Sylvia Brost Niels Steinebrunner Markus Büchler Peter Schemmer Martina Müller John J. Lemasters | 2012 | HPB Surgery2012，，： | 4 |
| 4 | Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8+ T‐cell responses in hepatocellular carcinoma显示文摘 | Tobias Flecken Nathalie Schmidt Sandra Hild Emma Gostick Oliver Drognitz Robert Zeiser Peter Schemmer Helge Bruns Thomas Eiermann David A. Price Hubert E. Blum Christoph Neumann‐Haefelin Robert Thimme | 2014 | Hepatology2014，，： | 2 |
| 5 | 活体肝脏微循环观测方法及应用显示文摘 | 梁锐 王立明 魏艾红 柳勤龙 唐顺雄 Peter Schemmer | 2008 | 微循环学杂志2008，18，1： | 2 |
| 6 | Quality of life after curative liver resection: A single center analysis显示文摘AIM: To evaluate quality of life (QoL) after curative liver resection and identify variables associated with decreased QoL. METHODS: From October 2001 to July 2004, 323 patients underwent liver resection. At 3-36 mo after discharge, 188 patients were disease free. QoL was assessed using the Short Form (SF)-12 Health Survey with mental and physical component scales (SF-12 MCS and PCS), supplemented with generic questions concerning pain and liver-specific items. RESULTS: Sixty-eight percent (128/188) returned the questionnaire, which was completed in 75% (96/128) of cases. Median SF-12 PCS and MCS were 46.7 (inter- quartile range: 34.2-53.9) and 54.1 (42.8-58.2). Fifty percent were pain free with a median symptom score of 1.75 (1.38-2.13). PCS was higher after major hepatec-tomy [57% (55/96)] compared to minor resection (P = 0.0049), which represented an improved QoL. QoL was not affected by sex but by age compared to the general German population. MCS was higher after liver surgery for metastatic disease [55.9 (47.5-58.8)] compared to primary carcinoma [49.6 (36.5-55.1)] and benign disease [49.2 (37.7-56.3)] (P = 0.0317). There was no correlation between length of postoperative period and QoL. Pain, def iciencies in everyday life and a high symptom score significantly decreased MCS and PCS. CONCLUSION: Most patients were only marginally affected even after major liver resection; however, minor complications were associated with decreased SF-12 MCS and PCS and need careful attention. | Helge Bruns Kirsten Krtschmer Ulf Hinz Anette Brechtel Monika Keller Markus W Büchler Peter Schemmer | 2010 | World Journal of Gastroenterology2010，16，19： | 2 |
| 7 | Intestinal transplantation: review of operative techniques显示文摘 | Arash Nickkholgh Pietro Contin Kareem Abu‐Elmagd Mohammad Golriz Daniel Gotthardt Christian Morath Peter Schemmer Arianeb Mehrabi | 2013 | Clin Transplant2013，，： | 1 |
| 8 | Ischemia/Reperfusion Injury in Liver Surgery and Transplantation显示文摘 | Peter Schemmer John J. Lemasters Pierre-Alain Clavien | 2012 | HPB Surgery2012，，： | 1 |
| 9 | Stapler Hepa tectomy is a Safe Dissection Technique: Analysis of 300 Patients显示文摘 | Peter Schemmer MD Helmut Friess MD | 2006 | World J Surg2006，30，： | 1 |
| 10 | Microvascular dysfunction in hepatic ischemia–reperfusion injury in pigs显示文摘 | Borimas K. Hanboon Wichai Ekataksin Guido Alsfasser Peter Schemmer Bernhard Urbaschek Robert S. McCuskey Ernst Klar | 2010 | Microvascular Research2010，，1： | 1 |
| 11 | Surgical Treatment of Primary Hepatic Epithelioid Hemangioendothelioma显示文摘 | Arianeb Mehrabi Arash Kashfi Peter Schemmer Peter Sauer Jens Encke Hamidreza Fonouni Helmut Friess Jürgen Weitz Jan Schmidt Markus W. Büchler Thomas W. Kraus | 2005 | Transplantation (S Suppl)2005，，1： | 1 |
| 12 | Bacteriobilia and fungibilia are associated with outcome in patients with endoscopic treatment of biliary complications after liver transplantation显示文摘 | Daniel Gotthardt Karl Weiss Christian Rupp Konrad Bode Isabella Eckerle Gerda Rudolph Janine Bergemann Petra Kloeters-Plachky Fadi Chahoud Markus Büchler Peter Schemmer Wolfgang Stremmel Peter Sauer | 2013 | Endoscopy2013，，： | 1 |
| 13 | Stapler Hepatectomy is a Safe Dissection Technique: Analysis of 300 Patients显示文摘 | Peter Schemmer Helmut Friess Ulf Hinz Arianeb Mehrabi Thomas W. Kraus Kaspar Z’graggen Jan Schmidt Waldemar Uhl Markus W. Büchler | 2006 | World Journal of Surgery2006，，3： | 1 |
| 14 | Early markers of reperfusion injury after liver transplantation: association with primary dysfunction显示文摘BACKGROUND:In patients with end-stage liver disease,liver transplantation is the only available curative treatment.Although the outcome and quality of life in the patients have improved over the past decades,primary dys-or nonfunction(PDF/PNF)can occur.Early detection of PDF and PNF is crucial and could lead to individual therapies.This study was designed to identify early markers of reperfusion injury and PDF in liver biopsies taken during the first hour after reperfusion.METHODS:Biopsies from donor livers were prospectively taken as a routine during the first hour after reperfusion.Recipient data,transaminases and outcome were routinely monitored.In total,10 biopsy specimens taken from patients with 90-day mortality and PDF,and patients with long-term survival but without PDF were used for DNA microarrays.Markers that were significantly up-or down-regulated in the microarray were verified using quantitative real-time PCR.RESULTS:Age,indications and lab MELD score were similar in both groups.Peak-transaminases during the first week after transplantation were significantly different in the two groups.In total,20 differentially regulated markers that correlated to PDF were identified using microarray analysis and verified with quantitative real-time PCR.CONCLUSIONS:The markers identified in this study could predict PDF at a very early time point and might point to interventions that ameliorate reperfusion injury and thus prevent PDF.Identification of patients and organs at risk might lead to individualized therapies and could ultimately improve outcome. | Helge Bruns Jan Heil Daniel Schultze Mohammed Al Saeedi Peter Schemmer | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，3： | 1 |
| 15 | Validation of Prognostic Scoring Systems for Patients Undergoing Resection of Colorectal Cancer Liver Metastases显示文摘 | Christoph Reissfelder Nuh N. Rahbari Moritz Koch Alexis Ulrich Isabel Pfeilschifter Anke Waltert Sascha A. Müller Peter Schemmer Markus W. Büchler Jürgen Weitz | 2009 | Annals of Surgical Oncology2009，，12： | 1 |
| 16 | C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation显示文摘 | Christoph Czerny Tom P. Theruvath Eduardo N. Maldonado Mark Lehnert Ingo Marzi Zhi Zhong John J. Lemasters Peter Schemmer | 2012 | HPB Surgery2012，，： | 1 |
| 17 | Sorafenib treatment is save and may affect survival of recurrent hepatocellular carcinoma after liver transplantation显示文摘 | Jan Pfeiffenberger Ronald Koschny Katrin Hoffmann Arianeb Mehrabi Anne Schmitz Boris Radeleff Wolfgang Stremmel Peter Schemmer Tom M. Ganten | 2013 | Langenbeck’s Archives of Surgery2013，，8： | 1 |
| 18 | Hepaticojejunostomy—Analysis of Risk Factors for Postoperative Bile Leaks and Surgical Complications显示文摘 | Dalibor Antolovic Moritz Koch Luis Galindo Sandra Wolff Emira Music Peter Kienle Peter Schemmer Helmut Friess Jan Schmidt Markus W. Büchler Jürgen Weitz | 2007 | Journal of Gastrointestinal Surgery2007，，5： | 1 |
| 19 | Ischemia/Reperfusion Injury in Liver Surgery and Transplantation显示文摘 | Peter Schemmer John J. Lemasters Pierre-Alain Clavien | 2012 | HPB Surgery2012，，： | 1 |
| 20 | Triptolide reverses hypoxia‐induced epithelial–mesenchymal transition and stem‐like features in pancreatic cancer by NF‐κB downregulation显示文摘 | Li Liu Alexei V. Salnikov Nathalie Bauer Ewa Aleksandrowicz Sabrina Labsch Clifford Nwaeburu Jürgen Mattern Jury Gladkich Peter Schemmer Jens Werner Ingrid Herr | 2014 | Cancer2014，，10： | 1 |
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