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| 1 | Radiologic-pathologic correlation of three-dimensional shear-wave elastographic findings in assessing the liver ablation volume after radiofrequency ablation显示文摘AIM: To evaluate the usefulness of three-dimensional(3D) shear-wave elastography(SWE) in assessing the liver ablation volume after radiofrequency(RF) ablation.METHODS: RF ablation was performed in vivo in 10 rat livers using a 15-gauge expandable RF needle. 3D SWE as well as B-mode ultrasound(US) were performed 15 min after ablation. The acquired 3D volume data were rendered as multislice images(interslice distance: 1.10 mm), and the estimated ablation volumes were calculated. The 3D SWE findings were compared against digitized photographs of gross pathological and histopathological specimens of the livers obtained in the same sectional planes as the 3D SWE multislice images. The ablation volumes were also estimated by gross pathological examination of the livers, and theresults were then compared with those obtained by 3D SWE.RESULTS: In B-mode US images, the ablation zone appeared as a hypoechoic area with a peripheral hyperechoic rim; however, the findings were too indistinct to be useful for estimating the ablation area. 3D SWE depicted the ablation area and volume more clearly. In the images showing the largest ablation area, the mean kPa values of the peripheral rim, central zone, and nonablated zone were 13.1 ± 1.5 kPa, 59.1 ± 21.9 kPa, and 4.3 ± 0.8 kPa, respectively. The ablation volumes depicted by 3D SWE correlated well with those estimated from gross pathological examination(r2 = 0.9305, P = 0.00001). The congestion and diapedesis of red blood cells observed in histopathological examination were greater in the peripheral rim of the ablation zone than in the central zone.CONCLUSION: 3D SWE outperforms B-mode US in delineating ablated areas in the liver and is therefore more reliable for spatially delineating thermal lesions created by RF ablation. | Katsutoshi Sugimoto Hisashi Oshiro Saori Ogawa Mitsuyoshi Honjo Takeshi Hara Fuminori Moriyasu | 2014 | World Journal of Gastroenterology2014,20,33: | 9 |
| 2 | Nuclear corepressor 1 expression predicts response to first-line endocrine therapy for breast cancer patients on relapse显示文摘背景雌激素受体 alpha (嗯一)是最重要的内分泌的治疗应答预言者因为有对内分泌的治疗的反应的预言的胸 cancer.The 精确性的女人被认为被包含雌激素受体 coregulatory 蛋白质和串音在之间影响嗯并且另外的生长发信号因素的 networks.Nuclear corepressor 1 ( NCOR1 )是学习客观的抄写 repressor.The 是在蛋白质 le 调查 NCOR1 | ZHANG Zhen-huan Hiroko Yamashita Tatsuya Toyama Yutaka Yamamoto Teru Kawasoe Mutsuko lbusuki Saori Tomita Hiroshi Sugiura Shunzo Kobayashi Yoshitaka Fujii Hirotaka Iwase | 2009 | Chinese Medical Journal2009,,15: | 4 |
| 3 | Low-dose rectal diclofenac for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial显示文摘 | Taiga Otsuka Seiji Kawazoe Shunya Nakashita Saori Kamachi Satoshi Oeda Chinatsu Sumida Takumi Akiyama Keisuke Ario Masaru Fujimoto Masanobu Tabuchi Takahiro Noda | 2012 | Journal of Gastroenterology2012,,8: | 4 |
| 4 | Phosphorylation of alphaB-crystallin in epiretinal membrane of human proliferative diabetic retinopathy显示文摘AIM: To examine phosphorylation of alpha B-crystallin(p-αBC), a vascular endothelial growth factor(VEGF)chaperone, and immunohistochemically investigate relationship between p-αBC, VEGF and phosphorylated p38-mitogen-activated protein kinase(p-p38 MAPK) in the epiretinal membrane of human proliferative diabetic retinopathy(PDR).METHODS: Eleven epiretinal membranes of PDR surgically excised were included in this study. Two normal retinas were also collected from enucleation tissues due to choroidal melanoma. Paraformaldehyde-fixed, paraffin-embedded tissue sections were processed for immunohistochemistry with anti-p-αBC, VEGF, CD31,and p-p38 MAPK antibodies.RESULTS: Immunoreactivity for p-αBC was observed in all of the epiretinal membranes examined, where phosphorylation on serine(Ser) 59 showed strongest immunoreactivity in over 70% of the membranes. The immunolocalization of p-αBC was detected in the CD31-positive endothelial cells, and co-localized with VEGF and p-p38 MAPK in PDR membranes. Immunoreactivity for p-αBC, however, was undetectable in endothelial cells of the normal retinas, where p-p38 MAPK immunoreactivity was less marked than PDR membranes.CONCLUSION: Phosphorylation of αBC, in particular,phosphorylation on Ser59 by p-p38 MAPK may play a potential role as a molecular chaperon for VEGF in the pathogenesis of epiretinal membranes in PDR. | Yoko Dong Zhenyu Dong Satoru Kase Ryo Ando Junichi Fukuhara Satoshi Kinoshita Saori Inafuku Yoshiaki Tagawa Erdal Tan Ishizuka Wataru Saito Miyuki Murata Atsuhiro Kanda Kousuke Noda Susumu Ishida | 2016 | International Journal of Ophthalmology(English edition)2016,9,8: | 4 |
| 5 | Endoscopic ultrasound-guided biliary drainage for right hepatic bile duct obstruction: novel technical tips显示文摘 | Takeshi Ogura Tatsushi Sano Saori Onda Akira Imoto Daisuke Masuda Kazuhiro Yamamoto Masayuki Kitano Toshihisa Takeuchi Takuya Inoue Kazuhide Higuchi | 2014 | Endoscopy2014,,: | 3 |
| 6 | Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinase (RSKs) promotes its binding to 14-3-3 and cytoplasmic localization显示文摘 | Naoya Fujita Saori Sato Takashi Tsuruo | 2003 | J Biol Chem2003,278,49: | 1 |
| 7 | Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases 显示文摘 | AKIHIRO T MAYUMI S SAORI K | 2007 | Liver lnt2007,27,1: | 1 |
| 8 | Freeze-drying of proteins with glass-forming oligosaccharide-derived sugar alcohols显示文摘 | SAORI KADOYA KAHORI FUJII KEN-ICHI IZUT- SU | 2010 | International Journal of Pharmaceutics2010,,389: | 1 |
| 9 | α-Glucosidase from a Strain of Deep-sea Geobaeillus : a Potential Enzyme for the Biosynthesis of Complex Carbohydrates显示文摘 | Vo Si Hung Yuji Hatada Saori Coda | 2005 | Appl Micro- biol Biotechnol2005,68,: | 1 |
| 10 | Academic libraries as learning spaces in Japan: Toward the development of learning commons 显示文摘 | Donkai Saori Toshimori Atsushi Mizoue Chieko | 2011 | International Information & Library Review2011,43,4: | 1 |
| 11 | Alteration in copy numbers of genes as a mechanism for acquired drug resistance显示文摘 | Yasui K Saori M Chen Z | 2004 | Cancer Res2004,64,4: | 1 |
| 12 | The onset of heat-induced testicular calcification in mice: involvement of the telomeric locus on Chromosome 1显示文摘 | Masataka Chihara Teppei Nakamura Naoki Sakakibara Saori Otsuka Osamu Ichii Yasuhiro Kon | 2014 | The American Journal of Pathology2014,,: | 1 |
| 13 | Preparation of new photosensitive ZrO2 gel films using hydroxyl-substituted modification reagents and their patterning显示文摘 | Saori Yamazaki Noboru tohge | 2004 | J Sol Gel Sci Technol2004,31,13: | 1 |
| 14 | Long-term exposure to traffic-related air pollution and the risk of death from hemorrhagic stroke and lung cancer in Shizuoka,Japan显示文摘 | Takashi Yorifuji Saori Kashima Toshihide Tsuda | 2013 | Science of the Total Environment2013,443,: | 1 |
| 15 | Genetically modified rice seeds accumulating GLP-1 analogue stimulate insulin secretion from a mouse pancreatic beta- cell line显示文摘 | KOICHI SUGITAA SAORI ENDO KASAHARAA YOSHIFUMI TADAB | 2005 | Federation of European Biochemical Societies2005,579,: | 1 |
| 16 | Pulmonary metastasis with endobronchial spread from sinonasal melanoma during a 9 year follow-up 显示文摘 | SAORI KOBAYASHI TAKAHIRO NAKAJIMA TOSHIHIKO IIZASA | 2010 | Inter Med2010,49,8: | 1 |
| 17 | Effects of proline mutations in the major house dust mite allergen Der f 2 on IgE-binding and histamine-releasing activity显示文摘 | Toshiro T Saori I Hideki H | 2000 | Eur J Biochem2000,267,: | 1 |
| 18 | Methods of preventing vinorelbine-induced phlebitis:An experimental study in rabbits显示文摘 | Emiko K Saori M Mayumi N | 2008 | Int J Med Sci2008,5,4: | 1 |
| 19 | Solution structure of Der f 2, the majou mite allergen for atopic disease显示文摘 | Saori I Hideki H Toshifumi Y | 1998 | J Biol Chem1998,273,: | 1 |
| 20 | Efficient production of L-(+)-lactic acid from raw starch by Streptococcus boris 148 显示文摘 | Junya Naritaa Saori Nakahara | 2004 | Journal of Bioscience and Bioengineering2004,97,6: | 1 |