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| 1 | Subtotal gastrectomy for gastric cancer显示文摘Although a steady decline in the incidence and mortality rates of gastric carcinoma has been observed in the last century worldwide,the absolute number of new cases/year is increasing because of the aging of the population. So far,surgical resection with curative intent has been the only treatment providing hope for cure;therefore,gastric cancer surgery has become a specialized field in digestive surgery. Gastrectomy with lymph node(LN) dissection for cancer patients remains a challenging procedure which requires skilled,well-trained surgeons who are very familiar with the fast-evolving oncological principles of gastric cancer surgery. As a matter of fact,the extent of gastric resection and LN dissection depends on the size of the disease and gastric cancer surgery has become a patient and 'diseasetailored' surgery,ranging from endoscopic resection to laparoscopic assisted gastrectomy and conventional extended multivisceral resections. LN metastases are the most important prognostic factor in patients that undergo curative resection. LN dissection remains the most challenging part of the operation due to the location of LN stations around major retroperitoneal vessels and adjacent organs,which are not routinely included in the resected specimen and need to be preserved in order to avoid dangerous intra-and postoperative complications.Hence,the surgeon is the most important non-TMN prognostic factor in gastric cancer.Subtotal gastrectomy is the treatment of choice for middle and distal-third gastric cancer as it provides similar survival rates and better functional outcome compared to total gastrectomy,especially in early-stage disease with favorable prognosis.Nonetheless,the resection range for middle-third gastric cancer cases and the extent of LN dissection at early stages remains controversial.Due to the necessity of a more extended procedure at advanced stages and the trend for more conservative treatments in early gastric cancer,the indication for conventional subtotal gastrectomy depends on multiple variables.This review aims to clarify and define the actual landmarks of this procedure and the role it plays compared to the whole range of new and old treatment methods. | Roberto Santoro Giuseppe M Ettorre Eugenio Santoro | 2014 | World Journal of Gastroenterology2014,20,38: | 9 |
| 2 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019,16,6: | 3 |
| 3 | Firm size and technology centrality in industry-university interactions显示文摘 | Santoro M Chakrabarti A | 2002 | Research Policy2002,,31: | 1 |
| 4 | Gastric cancer in elderly and young patients: a Western experience 显示文摘 | Santoro R Carlini M Carboni F | 2003 | Tumori2003,89,4: | 1 |
| 5 | miR-126 regu- lates angiogenic signaling and vascular integrity 显示文摘 | Fish J E Santoro M M Morton S U etal | 2008 | Dev Ce112008,15,2: | 1 |
| 6 | Arterial duct stenting: do we still need surgical shunt in congenital heart malformations with duct-dependent pulmonary circulation? 显示文摘 | Santoro G Gaio G Palladino M T | 2010 | J Cardiovasc Med ( Hagerstown)2010,11,11: | 1 |
| 7 | Analysis of right ventricular Doppler tissue imaging and load dependence in patients undergoing percutaneous closure of atrial septal defect显示文摘 | PASCOTTO M CASO P SANTORO G | 2004 | Am J Cardiol2004,94,9: | 1 |
| 8 | Spread spectrum fiber-optic local area network using optical processing显示文摘 | Prucnal P R Santoro M A Fan T R | 1986 | Lightwave Technol1986,4,5: | 1 |
| 9 | Carnitine and hemodialysis显示文摘 | Bellinghieri G Santoro D Calvani M | 2003 | American Journal of Kidney Diseases2003,41,31: | 1 |
| 10 | Ochratoxin A and Zear- alenone:a comparative study on genotoxic effects and cell death induced in bovine lymphocytes 显示文摘 | Lioi M Santoro A Barbieri R | 2004 | Mutation Research2004,557,: | 1 |
| 11 | Efficacy and safety of sorafenib in patients with advanced hepatocellu- lar carcinoma according to ECOG performance status: Asubanalysis from the SHARP trial显示文摘 | Raoul J Santoro A Beaugrand M | 2008 | J Clin Oncol(ASCO Meeting Abstracts)2008,26,15: | 1 |
| 12 | Alliance portfolio diversity and finn performance显示文摘 | Jiang R J Tao Q T Santoro M D | 2010 | Strategic Manage- ment Journal2010,31,10: | 1 |
| 13 | Comparison of the partial pro-teomesof the venoms of Brazilian spiders of thegenus Phoneutria 显示文摘 | Richardson M Pimenta AMC Bemquerer MP Santoro MM Beirao PS LimaME FiqueiredoSG Bloch C Jr Vasconcelos EA Campos FA GomesPC CordeiroMN | 2006 | CompBiochem PhysiolC2006,142,34: | 1 |
| 14 | Pharmaceutical policy in China显示文摘 | Sun Q Santoro M A Meng Q | 2008 | Health Affairs2008,27,4: | 1 |
| 15 | Long-term results with autogenous onlay graft in maxillary and mandibular atrophy显示文摘 | Santoro F Maiorana C Rabagliati M | 1999 | J Long Term EF Med Implants1999,9,3: | 1 |
| 16 | Molecular mechanism of cAMP modulation of HCN pacemaker channels 显示文摘 | Wainger BJ DeGennaro M Santoro B | 2001 | Nature2001,411,6839: | 1 |
| 17 | RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture 显示文摘 | Santoro M Meliilo RM Fusco A | 2006 | Eur J Endocrinol2006,155,5: | 1 |
| 18 | Adverse reaction to food : al- lergies and intolerances显示文摘 | Montalto M Santoro L D'Onofrio F | 2008 | Digestive Diseases2008,26,: | 1 |
| 19 | The application of external knowledge: Organizational conditions for exploration and exploitation 显示文摘 | Bierly P E Damanpour F Santoro M D | 2009 | Journal of Management Studies2009,46,3: | 1 |
| 20 | Relation between ST-segment changes and myocardial perfusion evaluated by myocardial contrast echocardiography in patients with acute myocardial infarction treated with direct angioplasty显示文摘 | Giovanni M Santoro Renato Valenti Piergiovanni Buonamici Leonardo Bolognese Giampaolo Cerisano Guia Moschi Maurizio Trapani David Antoniucci Pier Filippo Fazzini | 1998 | The American Journal of Cardiology1998,,8: | 1 |