|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation. | A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 2 | Signalling pathways regula- ring muscle mass in ageing skeletal muscle : the role of the IGF1-Akt- mTOR-FoxO pathway 显示文摘 | Sandri M Barberi L Bijlsma A Y | 2013 | Biogerontolagy2013，14，3： | 1 |
| 3 | Amphipathic, alpha-helical antimierobial peptides显示文摘 | Tossi A Sandri L Giangaspero A | 2000 | Biopolymers2000，55，1： | 1 |
| 4 | Hermite expansions of compact support waveforms: Applications to myoelectrie signals显示文摘 | LO CONTE L R MERLETTI R SANDRI G V | 1994 | IEEE Transactions on Biomedical Engineering1994，41，12： | 1 |
| 5 | Minor increases in plasma troponin I predict decreased left ventricular ejection fraction after high-dose chemotherapy显示文摘 | Sandri MT Cardinale D Zorzino L | 2003 | Clin Chem2003，49，2： | 1 |
| 6 | Changes in circulating tumor cell detection in patients with localized breast cancer before and after surgery显示文摘 | Sandri MT Zorzino L Cassatella MC | 2010 | Ann Surg Oncol2010，17，6： | 1 |
| 7 | Molecular Diversity in Gene-encoded,Cationic Antimicrobial Polypeptides显示文摘 | Sandri L | 2002 | Current Pharmaceutical Design2002，8，： | 1 |
| 8 | Signalling pathways reg- ulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway 显示文摘 | Sandri M Barberi L Bijlsma A Y | 2013 | Biogerontology2013，14，3： | 1 |
| 9 | Amphipathic a helical antimicrobial peptides显示文摘 | Giangaspero A Sandri L Tossi A | | 0，，21： | 1 |
| 10 | Safety of interferon beta treatment for chronic HCV hepatitis 显示文摘 | Festi D Sandri L Mazzella G | 2004 | World J Gastroenterol2004，10，： | 1 |
| 11 | Gallbladder cholesterol polyps and cholesterolosis 显示文摘 | Sandri L Colecchia A Lamcca A | 2003 | Minerva Gastroenterol Dietol2003，49，： | 1 |
| 12 | Amphipathic alpha helical antimicrobial peptices显示文摘 | GIANGASPERO A SANDRI L TOSSI A | 2001 | Eur J Biochem2001，268，21： | 1 |
| 13 | Posttranslational modifications control FoxO3 activity during denervation 显示文摘 | Bertaggia E Coletto L Sandri M | 2012 | Am J Physiol Cell Physiol2012，302，3： | 1 |
| 14 | A Bayesian procedure for probabilistic tsunami hazard assessment 显示文摘 | Grezio A Marzocchi W Sandri L | 2010 | Natural hazards2010，53，01： | 1 |
| 15 | Frequency response requirements for fluctuating wind pressure measurements显示文摘 | LETCHFORD C W SANDRI P LEVITAN M L | 1992 | J Wind Eng Ind Aerodyn1992，40，3： | 1 |
| 16 | Amphipathic, alpha-helical antimicrobial peptides显示文摘 | l'ossi A Sandri L Giangaspero A | 2000 | Biopolymers2000，55，1： | 1 |
| 17 | The 2B myosin heavy chain gene is expressed in human skeletal muscle显示文摘 | Andersen J L Weissn A Sandri C | 2002 | Journal of Physiology2002，，93： | 1 |
| 18 | Apoptosis in the skeletal muscle of patients with heart failure:investigation of clinical and biochemical changes显示文摘 | Vescovo G Volterrani M Zennaro R Sandri M Ceconi C Lorusso R Ferrari R Ambrosio GB and Dalla Libera L | | Heart0，2000，： | 1 |
| 19 | Safety of interferon beta treatment for chronic HCV hepatitis显示文摘 | Festi D Sandri L Mazzella G | 2004 | World J Gastroenterol2004，10，1： | 1 |
| 20 | Amphipathic alpha helical an timicrobial peptides显示文摘 | Giangaspero A Sandri L Tossi A | 2001 | Eur J Biochem2001，268，21： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员