|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Assessment of the correlation between serum prolidase and alpha-fetoprotein levels in patients with hepatocellular carcinoma显示文摘AIM: To determine the predictive value of increased prolidase activity that reflects increased collagen turnover in patients with hepatocellular carcinoma(HCC).METHODS: Sixty-eight patients with HCC(mean age of 69.1 ± 10.1), 31 cirrhosis patients(mean age of59.3 ± 6.3) and 33 healthy volunteers(mean age of51.4 ± 12.6) were enrolled in this study. Univariate and multivariate analysis were used to evaluate the association of serum α-fetoprotein(AFP) values with HCC clinicopathological features, such as tumor size,number and presence of vascular and macrovascular invasion. The patients with HCC were divided into groups according to tumor size, number and presence of vascular invasion(diameters; ≤ 3 cm, 3-5 cmand ≥ 5 cm, number; 1, 2 and ≥ 3, macrovascular invasion; yes/no). Barcelona-clinic liver cancer(BCLC)criteria were used to stage HCC patients. Serum samples for measurement of prolidase and alphafetoprotein levels were kept at-80 ℃ until use.Prolidase levels were measured spectrophotometrically and AFP concentrations were determined by a chemiluminescence immunometric commercial diagnostic assay.RESULTS: In patients with HCC, prolidase and AFP values were evaluated according to tumor size, number,presence of macrovascular invasion and BCLC staging classification. Prolidase values were significantly higher in patients with HCC compared with controls(P <0.001). Prolidase levels were significantly associated with tumor size and number(P < 0.001, P = 0.002,respectively). Prolidase levels also differed in patients in terms of BCLC staging classification(P < 0.001).Furthermore the prolidase levels in HCC patients showed a significant difference compared with patients with cirrhosis(P < 0.001). In HCC patients grouped according to tumor size, number and BCLC staging classification, AFP values differed separately(P = 0.032,P = 0.038, P = 0.015, respectively). In patients with HCC, there was a significant correlation(r = 0.616; P< 0.001) between prolidase and AFP values in terms of tumor size, number and BCLC staging classification,whereas the presence of macrovascular invasion did not show a positive association with serum prolidase and AFP levels.CONCLUSION: Considering the levels of both serum prolidase and AFP could contribute to the early diagnosing of hepatocellular carcinoma. | Sevil Uygun Ilikhan Muammer Bilici Hatice Sahin Ayse Semra Demir Akca Murat Can Ibrahim Ilker Oz Berrak Guven M Cagatay Buyukuysal Yucel Ustundag | 2015 | World Journal of Gastroenterology2015，21，22： | 8 |
| 2 | Fruit Yield and Quality, and Irrigation Water Use Efficiency of Summer Squash Drip-Irrigated with Different Irrigation Quantities in a Semi-Arid Agricultural Area显示文摘Fruit yield, yield components, fruit mineral content, total p henolic content, antioxidant activity and irrigation water use efficiency(IWUE) of summer squash responses to different irrigation quantities were evaluated with a field study. Irrigations were done when the total evaporated water from a Class A pan was about 30 mm. Different irrigation quantities were adjusted using three different plant-pan coefficients(Kcp, 100%(Kcp1), 85%(Kcp2) and 70%(Kcp3)). Results indicated that lower irrigation quantities provided statistically lower yield and yield components. The highest seasonal fruit yield(80.0 t ha-1) was determined in the Kcp1 treatment, which applied the highest volume of irrigation water(452.9 mm). The highest early fruit yield, average fruit weight and fruit diameter, length and number per plant were also determined in the Kcp1 treatment, with values of 7.25 t ha-1, 264.1 g, 5.49 cm, 19.95 cm and 10.92, respectively. Although the IWUE value was the highest in the Kcp1 treatment(176.6 kg ha-1 mm-1), it was statistically similar to the value for Kcp3 treatment(157.1 kg ha-1 mm-1). Total phenolic content and antioxidant activity of fruits was higher in the Kcp1(44.27 μg gallic acid equivalents(GAE) mg-1 fresh sample) and in the Kcp2(84.75%) treatments, respectively. Major(Na, N, P, K, Ca, Mg and S) and trace(Fe, Cu, Mn, Zn and B) mineral contents of squash fruits were the highest in the Kcp2 treatment, with the exception of P, Ca and Cu. Mineral contents and total phenolic content were significantly affected by irrigation quantities, but antioxidant activity was not affected. It can be concluded that the Kcp1 treatment was the most suitable for achieving higher yield and IWUE. However, the Kcp2 treatment will be the most suitable due to the high fruit quality and relatively high yield in water shortage conditions. | Yasemin Kuslu Ustun Sahin Fatih M Kiziloglu Selcuk Memis | 2014 | Journal of Integrative Agriculture2014，13，11： | 5 |
| 3 | 老年男性勃起功能及迟发性性腺功能减退症状与下尿路症状严重性的关系显示文摘本文旨在研究土耳其爱琴海地区的老年男性下尿路症状(LUTSs)、勃起功能障碍(ED)和有症状的迟发性性腺功能减退症(SLOH)三者间的关系。符合以下标准的500名男性患者被纳入该研究:40周岁以上;过去6个月内有稳定的性关系;在六个泌尿外科诊所之一进行过就诊登记。每位患者均行血清PSA、睾酮水平及尿流率的检测,并填写国际前列腺症状评分和生活质量评分(IPSS-QoL)量表、国际勃起功能指数(IIEF)问卷和老年男性症状(AMS)量表。在所有的研究对象中,23.9%的患者有轻度LUTSs,53.3%有中度LUTSS,22.8%有重度LUTSS。每组间总睾酮水平无明显差异。除此之外,69.6%的病人患有ED,且ED的发生率与LUTS严重性呈正相关。71.2%的患者出现SLOH(AMS〉27),且IPSS评分越高,严重的性腺功能减退症状的发生率也越高。相关性分析显示以上三种问卷分数之间有显著关联。总之,LUTS严重性是ED和SLOH的非年龄依赖性危险因素,LUTS严重性和SLOH症状之间似乎有显著的相关性,但还需要从病因学和生物学角度进行深入阐明。 | Ozan Bozkurt Deniz Bolat Omer Demir Oktay Ucer Ali Sahin Burak Ozcift Abdulkadir Pekta Tahir Turan Bilal H Gümü Ertan Cans Ahmet Bolukbasi Haluk Erol Adil Esenx | 2013 | Asian Journal of Andrology2013，15，6： | 4 |
| 4 | Comparison of in-sulin monotherapy and combination therapy with insulinand metformin or insulin and rosiglitazone or insulin andacarbose in type 2 diabetes显示文摘 | Yilmaz H Gursoy A Sahin M | 2007 | Acta Diabetol2007，44，4： | 1 |
| 5 | Leptin and TNF-αlpha levels in pa-tients with chronic obstructive pulmonary disease and their relationship to nutritional parameters显示文摘 | Calikoglu M Sahin G Unlu A | 2004 | Respiration2004，71，1： | 1 |
| 6 | Myocardial performanceindex and aortic distensibility in patients with different leftventricle geometry in newly diagnosed essential hypertension 显示文摘 | Sahin DY Giir M Elbasan Z | 2013 | Blood Press2013，22，5： | 1 |
| 7 | The importance of internet usage for urologic patients显示文摘 | Sahin C Tuncer M Yazici O | 2014 | Arch Ital Urol Androl2014，86，4： | 1 |
| 8 | Human neoplasms elicit multiple specific immune responses in the autologous host显示文摘 | Sahin U Tureci O Pfreundschuh M | 1995 | Proc Natl Acad Sci USA1995，92，11： | 1 |
| 9 | Diagnostic value of MRCP in biliary pancreatitis : result of long - term follow - up 显示文摘 | OKAN I BAS G SAHIN M | 2012 | Acta Chit Belg2012，112，5： | 1 |
| 10 | Mechanical and elec- tronic properties of MoS2 nanoribbons and their defects 显示文摘 | ATACA C SAHIN M AKTURK E | 2011 | The Journal of Physical Chemistry C2011，115，10： | 1 |
| 11 | Effects of dietary combination of chromium and biotin on egg production, serum metabolites, and egg yolk mineral and cholesterol concentrations in heat-distressed laying quails显示文摘 | Sahin K Onderci M Sahin N | 2004 | Biol Trace Elem Res2004，101，2： | 1 |
| 12 | The relation between impaired glucose tolerance and slow coronary flow显示文摘 | Binak E Gunduz H Sahin M | 2006 | Cardiol2006，111，1： | 1 |
| 13 | Effect of dietary chromium and zinc on egg production, egg quality, and some blood metabolites of laying hens reared under low ambient temperature 显示文摘 | Sahin N Onderci M Sahin K | 2002 | Biol Trace Elem Res2002，85，1： | 1 |
| 14 | Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abltransformed myeloid cell lines显示文摘 | Sahin M B Perman S M Jenjins G | 1999 | Leukemia1999，13，： | 1 |
| 15 | Characterization of autism in young children with tuberous sclerosis complex 显示文摘 | Jeste SS Sahin M Bolton P | 2008 | J Child Neurol2008，23，5： | 1 |
| 16 | Photocatalytic hydrogen production by direct sun light from sulfide/sulfite solution显示文摘 | KOCA A SAHIN M | 2002 | Int J Hydrogen Energy2002，27，4： | 1 |
| 17 | Curcumin Ameloriates Heat Stress Via Inhibition of Oxidative Stress and Modulation of Nrf2/HO - 1 Pathway in Quail 显示文摘 | Sahin K C Oran M Tuzcu N | 2012 | Food Chem Toxico12012，50，11： | 1 |
| 18 | Loss ofCD20 antigen expression after rituximab therapy ofCD20 positive B cell lymphoma ( diffuse large B cellextranodal marginal zone lymphoma combination) : Acase report and review of the literature显示文摘 | DUMAN B B SAHIN B ERGIN M | 2012 | Med On-col2012，29，： | 1 |
| 19 | Sensitization of Cervical Cancer C- ells to Cisplatin by Genistein: The Role of NFkappaB and Akt/mTOR Signaling Pathways 显示文摘 | Sahin K Tuzcu M Basal( N | 2012 | J Oncol2012，2012，46： | 1 |
| 20 | Effect of martensite volume fraction and tempering time on abrasive wear of ferritic ductile iron with dual matrix显示文摘 | SAHIN Y ERDOGAN M CERAH M | 2008 | Wear2008，265，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员