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| 1 | A data-driven health indicator extraction method for aircraft air conditioning system health monitoring显示文摘Prognostics and Health Management(PHM) has become a very important tool in modern commercial aircraft. Considering limited built-in sensing devices on the legacy aircraft model,one of the challenges for airborne system health monitoring is to find an appropriate health indicator that is highly related to the actual degradation state of the system. This paper proposed a novel health indicator extraction method based on the available sensor parameters for the health monitoring of Air Conditioning System(ACS) of a legacy commercial aircraft model. Firstly, a specific Airplane Condition Monitoring System(ACMS) report for ACS health monitoring is defined. Then a non-parametric modeling technique is adopted to calculate the health indicator based on the raw ACMS report data. The proposed method is validated on a single-aisle commercial aircraft widely used for short and medium-haul routes, using more than 6000 ACMS reports collected from a fleet of aircraft during one year. The case study result shows that the proposed health indicator can effectively characterize the degradation state of the ACS, which can provide valuable information for proactive maintenance plan in advance. | Jianzhong SUN Chaoyi LI Cui LIU Ziwei GONG Ronghui WANG | 2019 | Chinese Journal of Aeronautics2019，32，2： | 14 |
| 2 | Therapeutic effect of electroacupuncture,massage,and blocking therapy on external humeral epicondylitis显示文摘OBJECTIVE:To compare two therapeutic methods:electroacupuncture + massage + blocking therapy,and blocking therapy alone in the treatment of external humeral epicondylitis.METHODS:Eighty-six patients were randomized into two groups with 43 in each. The treatment group received electroacupuncture + massage +blocking therapy, while the control group received blocking therapy only. A course of electroacupuncture treatment included therapy once a day for 10days. There were 10 treatments in a massage course and massage was given once a day, with a1-week interval given before the next course. A course of blocking treatment included therapy once a week, for twototaltreatments,andgenerallyno more than three times. The therapeutic effects were evaluated with the visual analog scale(VAS),grip strength index(GSI) score, and Mayo elbow performance score(MEPS) before treatment and at0, 6, 12, and 24 months after treatment to observe thetotaleffectiverate.RESULTS: In the treatment and control groups before treatment and at 0, 6, 12, and 24 months after treatment, the VAS scores were: 6.5±1.9 and 6.4±1.6; 4.6±1.3 and 4.6±1.7; 4.8±1.3 and 4.8±1.2; 4.6±1.2 and 6.6±1.6; and 6.5±1.6 and 6.5±1.3, respectively. The GSI scores were 63±8 and 63±8; 84±6and82±7;82±7and82±6;84±6and62±8;and64±6 and 64±7, respectively.The MEPS of both groups were65±7and66±8;85±6and84±7;84±5and84±7;80±7and66±6;and65±6and65±7,respectively.The total effective rates of the treatment and control groups at 0, 6, 12, and 24 months after treatment were 87.5% and 85.0%; 85.0% and 82.5%;80.0% and 12.5%; and 2.5% and 5.0%, respectively.Compared with the treatment group, the control group had greater joint function, better the rapeutic effect, and lower pain intensity(P<0.01), indicating a high recurrence rate in the 12th month after treatment.There were no differences inVAS, GSI, or MEPS at 0, 6, and 24 months after treatment(P>0.05)betweenthetwogroups.CONCLUSION: We found that both methods were effective for external humeral epicondylitis. After 6months of treatment,the effects were good in both groups. However, in the 12th month, the control group had a relatively severe relapse. After 24months, both groups relapsed. The effect of electroacupuncture, massage, and blocking therapy used in combination lasted longer, delaying the recurrence of the disease. | Xinjian Li Kun Zhou Enming Zhang Zhen xiQi Weiqing Sun Liangfu Xu Jianfeng Xu Youzhi Cai Ronghui Wang | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 6 |
| 3 | Tapering-induced enhancement of light extraction efficiency of nanowire deep ultraviolet LED by theoretical simulations显示文摘A nanowire(NW) structure provides an alternative scheme for deep ultraviolet light emitting diodes(DUV-LEDs)that promises high material quality and better light extraction efficiency(LEE). In this report, we investigate the influence of the tapering angle of closely packed Al Ga N NWs, which is found to exist naturally in molecular beam epitaxy(MBE) grown NW structures, on the LEE of NW DUV-LEDs. It is observed that, by having a small tapering angle, the vertical extraction is greatly enhanced for both transverse magnetic(TM) and transverse electric(TE) polarizations. Most notably, the vertical extraction of TM emission increased from 4.8% to 24.3%,which makes the LEE reasonably large to achieve high-performance DUV-LEDs. This is because the breaking of symmetry in the vertical direction changes the propagation of the light significantly to allow more coupling into radiation modes. Finally, we introduce errors to the NW positions to show the advantages of the tapered NW structures can be projected to random closely packed NW arrays. The results obtained in this paper can provide guidelines for designing efficient NW DUV-LEDs. | RONGHUI LIN SERGIO VALDES GALAN HAIDING SUN YANGRUI HU MOHD SHARIZAL ALIAS BILAL JANJUA TIEN KHEE NG BOON S.OOI XIAOHANG LI | 2018 | Photonics Research2018，6，5： | 3 |
| 4 | A Novel Fiber Bragg Grating with Triangular Spectrum and Its Application in Strain Sensor显示文摘A novel fiber Bragg grating with triangular spectrum is presented. A strain sensor based on this fiber grating is proposed. Experiments showed that the sensor has advantages of high sensitivity, wider measuring range and immunity to fluctuation of the light source power. | Rui Huang, Yingwu Zhou, Guowei Sun, Ronghui Qu, Zujie Fang Shanghai Institute of Optics and Fine Mechanics, CAS, P. R. China | 2003 | 光学学报2003，23，S1： | 2 |
| 5 | Metastable state of gas hydrate during decomposition: A novel phenomenon显示文摘Natural gas hydrates are solid compounds with cage-like structures formed by gas and water.An intriguing phenomenon that gas hydrates can dissociate at a low rate below the ice freezing point has been viewed as the metastability of hydrate.The mechanisms of hydrate metastability have been widely studied,and many mechanisms were proposed involving the self-preservation effect,supercooled water-gas-hydrate metastable equilibrium,and supersaturated liquid-gas-hydrate system etc.The metastable state of hydrate could be of crucial significance in the kinetics of hydrate formation and decomposition,heat and mass transfer during gas production processes,and the application of hydrate-based technique involving desalination,energy storage and transportation,and gas separation and sequestration.Few researches have systematically considered this phenomenon,and its mechanism remains unclear.In this work,various mechanisms and hypothesis explaining the metastable state of gas hydrates were introduced and discussed.Further studies are still required to reveal the intrinsic nature of this metastable state of gas hydrate,and this work could give some implications on the existing theory and current status of relevant efforts. | Ronghui Sun Zhen Fan Lei Yang Yuanping Li Xin Lü Yang Miao | 2020 | Chinese Journal of Chemical Engineering2020，28，4： | 1 |
| 6 | Unconventional quantum gate based on Rydberg blockade mechanism显示文摘We propose a scheme for realizing an unconventional three-qubit controlled-phase gate via the Rydberg blockade mechanism.The qubit is encoded by atomic ensembles that are trapped in optical traps and fixed on an atom chip.Because of the collective nature of the encoding and the Rydberg blockade mechanism,the scheme do not require separate addressing of individual atoms.The time needed for the gate operation is much shorter than that in a similar scheme.In addition,we show the gate can be used as a basic tool for effective generation of large-scale 2D cluster states. | SUN RongHui YE MingYong LIN XiuMin | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，9： | 1 |
| 7 | Impacts of the tropical western Pacific on the East Asian summer monsoon显示文摘 | HUANG Ronghui SUN Fengying | 1992 | J Meteor Soc Japan1992，70，1： | 1 |
| 8 | Targeting papain-like protease for broad-spectrum coronavirus inhibition显示文摘The emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades emphasize the need for next-generation pan-coronaviral therapeutics.Drugging the multi-functional papain-like protease(PLpro)domain of the viral nsp3 holds promise.However,none of the known coronavirus PLpro inhibitors has been shown to be in vivo active.Herein,we screened a structurally diverse library of 50,080 compounds for potential coronavirus PLpro inhibitors and identified a noncovalent lead inhibitor F0213 that has broad-spectrum anti-coronaviral activity,including against the Sarbecoviruses(SARSCoV-1 and SARS-CoV-2),Merbecovirus(MERS-CoV),as well as the Alphacoronavirus(hCoV-229E and hCoVOC43).Importantly,F0213 confers protection in both SARS-CoV-2-infected hamsters and MERS-CoV-infected human DPP4-knockin mice.F0213 possesses a dual therapeutic functionality that suppresses coronavirus replication via blocking viral polyprotein cleavage,as well as promoting antiviral immunity by antagonizing the PLpro deubiquitinase activity.Despite the significant difference of substrate recognition,mode of inhibition studies suggest that F0213 is a competitive inhibitor against SARS2-PLpro via binding with the 157K amino acid residue,whereas an allosteric inhibitor of MERSPLpro interacting with its 271E position.Our proof-ofconcept findings demonstrated that PLpro is a valid target for the development of broad-spectrum anticoronavirus agents.The orally administered F0213 may serve as a promising lead compound for combating the ongoing COVID-19 pandemic and future coronavirus outbreaks. | Shuofeng Yuan Xiaopan Gao Kaiming Tang Jian-Piao Cai Menglong Hu Peng Luo Lei Wen Zi-Wei Ye Cuiting Luo Jessica Oi-Ling Tsang Chris Chun-Yiu Chan Yaoqiang Huang Jianli Cao Ronghui Liang Zhenzhi Qin Bo Qin Feifei Yin Hin Chu Dong-Yan Jin Ren Sun Jasper Fuk-Woo Chan Sheng Cui Kwok-Yung Yuen | 2022 | Protein & Cell2022，13，12： | 0 |
| 9 | Design and simulation of a novel E-mode GaN MIS-HEMT based on a cascode connection for suppression of electric field under gate and improvement of reliability显示文摘We proposed a novel Al Ga N/Ga N enhancement-mode(E-mode) high electron mobility transistor(HEMT) with a dual-gate structure and carried out the detailed numerical simulation of device operation using Silvaco Atlas. The dual-gate device is based on a cascode connection of an E-mode and a D-mode gate. The simulation results show that electric field under the gate is decreased by more than 70% compared to that of the conventional E-mode MIS-HEMTs(from 2.83 MV/cm decreased to 0.83 MV/cm). Thus, with the discussion of ionized trap density, the proposed dual-gate structure can highly improve electric field-related reliability, such as, threshold voltage stability. In addition, compared with HEMT with field plate structure, the proposed structure exhibits a simplified fabrication process and a more effective suppression of high electric field. | Weiyi Li Zhili Zhang Kai Fu Guohao Yu Xiaodong Zhang Shichuang Sun Liang Song Ronghui Hao Yaming Fan Yong Cai Baoshun Zhang | 2017 | Journal of Semiconductors2017，38，7： | 0 |
| 10 | SY-1530, a highly selective BTK inhibitor, effectively treats B-cell malignancies by blocking B-cell activation显示文摘Objective:B-cell antigen receptor(BCR)signaling is required to maintain the physiological functions of normal B cells and plays an important pathogenic role in B-cell malignancies.Bruton tyrosine kinase(BTK),a critical mediator of BCR signaling,is an attractive target for the treatment of B-cell malignancies.This study aimed to identify a highly potent and selective BTK inhibitor.Methods:Homogeneous time-resolved fluorescence assays were used to screen BTK inhibitors.Typhoon fluorescence imaging and Western blot analysis were used to confirm the effects of SY-1530 on the BCR signaling pathway.Additionally,the anti-tumor activities of SY-1530 were evaluated in TMD8 xenografts and spontaneous canine B-cell lymphoma.Results:We found a novel irreversible and non-competitive inhibitor of BTK,SY-1530,which provided dose-dependent and timedependent inhibition.SY-1530 selectively bound to BTK rather than inducible T-cell kinase;consequently,it did not significantly affect T-cell receptor signaling and caused limited off-target effects.SY-1530 blocked the BCR signaling pathway through downregulation of BTK activity,thus leading to impaired phosphorylation of BTK and its downstream kinases.Moreover,SY-1530 induced apoptosis in a caspase-dependent manner and efficaciously inhibited tumor growth in mouse xenograft models of B-cell malignancy(P<0.001).SY-1530 also induced positive clinical responses in spontaneous canine B-cell lymphoma.Conclusions:SY-1530 is an irreversible and selective BTK inhibitor that shows inhibitory effects on B-cell malignancies by blocking the BCR signaling pathway.Therefore,it may be a promising therapeutic approach for the treatment of B-cell malignancies. | Liao Wang Yinghui Sun Xijie Liu Hongjuan Li Chang Lu Ronghui Yang Chuanzhen Yang Binghui Li | 2022 | Cancer Biology & Medicine2022，19，7： | 0 |
| 11 | Morphology-controlled porphyrin nanocrystals with enhanced photocatalytic hydrogen production显示文摘Molecular self-assembly is a natured-inspired strategy to integrate individual functional molecules into supramolecular nanostructured materials through noncovalent bond interactions for solar to fuel conversion.However,the design and engineering of the morphology,size,and orderly stacking of supramolecular nanostructures remain a great challenge.In this study,regular porphyrin nanocrystals with different orderly stacked structures are synthesized through noncovalent self-assembly of Pt(II)meso-tetra(4-carboxyphenyl)porphine(PtTCPP),using surfactants with different electronegativity.The synergy of noncovalent bond interactions between porphyrin molecules,and between porphyrin molecules and surfactants resulted in different molecular packing patterns.Due to the spatial ordering of PtTCPP molecules,the different nanocrystals exhibit both collective optical properties and morphology-dependent activities in photocatalytic hydrogen production.The measurements of the photodeposition of dual cocatalysts showed that the photogenerated electrons and holes selectively aggregated at different active sites,revealing separation pathways and directional transfer of photogenerated electrons and holes in the assemblies.This study provides a new strategy to exert rational control over porphyrin self-assembly nanocrystals for highly efficient water splitting. | Ronghui Cao Jinghan Wang Yusen Li Jiajie Sun Feng Bai | 2022 | Nano Research2022，15，6： | 0 |
| 12 | Erosion Mechanism of Al_(2)O_(3)-SiC Castables for Lining Maintenance in Blast Furnace Hearths显示文摘Al_(2)O_(3)-SiC castables,for the relining of BF hearths in mid-campaign repair,were sampled and investigated after two years’service.The chemical and mineralogical characteristics of the residual castables were analyzed by X-ray diffraction,scanning electron microscopy,and energy dispersive X-ray spectrometry to study the erosion mechanism.The results show that as gaseous K diffuses in the castables,leucite(KAlSi_(2)O_(8))and multiple cracks are formed.Molten iron and slag penetrate through the cracks to form anorthite([Ca,Na][Al,Si]_(4)O_(8))and iron,which will not form an embrittlement layer similar to carbon bricks.The entire repair of the hearth with Al_(2)O_(3)-SiC castables combined with the design of thin-wall lining hearth eliminates“elephant foot shaped”erosion,greatly prolonging the service life of the hearth lining. | SUN Saiyang MA Xiaoqing WANG Xingwei ZHAO Yong ZHANG Ronghui FEI Weibao | 2022 | China's Refractories2022，31，2： | 0 |
| 13 | FvWRKY50 is an important gene that regulates both vegetative growth and reproductive growth in strawberry显示文摘The WRKY transcription factors play important roles in plant growth and resistance,but only a few members have been identified in strawberry.Here we identified a WRKY transcription factor,FvWRKY50,in diploid strawberry which played essential roles in strawberry vegetative growth,and reproductive growth.Knocking out FvWRKY50 by genome editing accelerated flowering time and leaf senescence but delayed anthocyanin accumulation in fruit.Further analysis showed that FvWRKY50 acted as a transcriptional repressor to negatively regulate the expression of flowering-and leaf senescence-related genes,including FvFT2,FvCO,FvFT3,and FvSAUR36.Notably,FvWRKY50 directly upregulated the expression of FvCHI and FvDFR by binding their promoter under normal conditions,but at low temperature FvWRKY50 was phosphorylated by FvMAPK3 and then induced protein degradation by ubiquitination,delaying anthocyanin accumulation.In addition,the homozygous mutant of FvWRKY50 was smaller while the biallelic mutant showed normal size.These new findings provide important clues for us to further reveal the regulatory mechanisms of strawberry growth and fruit ripening. | Yating Chen Liping Liu Qianqian Feng Chuang Liu Yujuan Bao Nan Zhang Ronghui Sun Zhaonan Yin Chuanfei Zhong Yuanhua Wang Qian Li Bingbing Li | 2023 | Horticulture Research2023，10，7： | 0 |
| 14 | Passive target tracking using marginalized particle filter显示文摘A marginalized particle filtering (MPF) approach is proposed for target tracking under the background of passive measurement.Essentially,the MPF is a combination of particle filtering technique and Kalman filter. By making full use of marginalization,the distributions of the tractable linear part of the total state variables are updated analytically using Kalman filter,and only the lower-dimensional nonlinear state variable needs to be dealt with using particle filter.Simulation studies are performed on an illustrative example,and the results show that the MPF method leads to a significant reduction of the tracking errors when compared with the direct particle implementation.Real data test results also validate the effectiveness of the presented method. | Zhan Ronghui Wang Ling Wan Jianwei Sun Zhongkang | 2007 | Journal of Systems Engineering and Electronics2007，18，3： | 0 |
| 15 | Mossbauer Study of Amorphization in Energetic Ar Ion Irradiated Garnet显示文摘Mossbauer Study of Amorphization in Energetic Ar Ion Irradiated Garnet￥MengQinghua;JinYunfan;XuRonghui;QuanJingming;SunYoumei... | Meng Qinghua Jin Yunfan Xu Ronghui Quan Jingming Sun Youmei Wang Zhiguang Ma Feng Han Jin Liu Gang Liu Jie and Li Changlin | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
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