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7篇 您的检索式:作者名="Russell Katherine"
    题名 作者 年代 出处 被引量
1Therapeutic regulation of autophagy in hepatic metabolism显示文摘Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especially relevant in the liver, a key metabolic organ thatgoverns body energy metabolism. Autophagy’s role in hepatic energy regulation has just begun to emerge and autophagy seems to have a much broader impact than what has been appreciated in the field. Though classically known for selective or bulk degradation of cellular components or energy-dense macromolecules, emerging evidence indicates autophagy selectively regulates various signaling proteins to directly impact the expression levels of metabolic enzymes or their upstream regulators. Hence, we review three specific mechanisms by which autophagy can regulate metabolism: A) nutrient regeneration, B) quality control of organelles, and C) signaling protein regulation. The plasticity of the autophagic function is unraveling a new therapeutic approach. Thus, we will also discuss the potential translation of promising preclinical data on autophagy modulation into therapeutic strategies that can be used in the clinic to treat common metabolic disorders.Katherine Byrnes Sophia Blessinger Niani Tiaye Bailey Russell Scaife Gang Liu Bilon Khambu 2022Acta Pharmaceutica Sinica B2022,12,1:11
2Synthesis of platelet-derived growth factor by cells of splenic red pulp in normal rats显示文摘Russell E. Dill E. Katherine Miller Barbara J. Dyer Anthony M. Iacopino 1994Cell and Tissue Research1994,,1:1
3Nutrient Intakes and Adenocarcinoma of the Esophagus and Distal Stomach显示文摘Honglei Chen Katherine L. Tucker Barry I. Graubard Ellen F. Heineman Rodney S. Markin Nancy A. Potischman Robert M. Russell Dennis D. Weisenburger Mary H. Ward 2002Nutrition and Cancer2002,,1:1
4Bibliotherapy in the treatment of female orgasmic dysfunction显示文摘Dodge Laura T Glasgow Russell E ONeill H Katherine 1982Journal of Consult- ing and Clinical Psychology1982,50,3:1
5Hepatitis E vi- rus in blood components: a prevalence and transmis- sion study in southeast England显示文摘Hewitt Patricia E Ijaz Samreen Brailsford Su R Brett Rachel Dicks Steven Haywood Becky Kenne- dy Iain T R Kitchen Alan Patel Poorvi Poh John Russell Katherine Tettmar Kate I Tossell Joanne Ushiro-Lumb Ines Tedder Richard S 2014Lancet2014,384,9956:1
6Supportive use of megestrol acetate (Megace) with head/neck and lung cancer patients receiving radiation therapy显示文摘Richard P McQuellon Dawn B Moose Gregory B Russell L.Douglas Case Katherine Greven Michael Stevens Edward G Shaw 2002International Journal of Radiation Oncology, Biology, Physics2002,,5:1
7吸入性曲霉病显示文摘2007年5月,一名47岁男性以咳嗽咯痰1周、胸痛、渐进性气短、发热及肌肉疼痛为主诉入院:患者是一名焊工,除吸烟嗜好(每天约10支)外,无特殊病史,既往健康状况良好。入院查体:呼吸30次/min,体温38℃;双肺布满粗湿啰音(大水泡音);白细胞计数18.6×10^9/L,中性粒细胞17.3×10^9/L,淋巴细胸0.4×10^9/L;胸部X线片显示双肺大量不规则结节.Katherine Russell Carl Broadbridge Sebastian Murray David Wagharn Allan Mahaney 李豪刚(译) 2009世界临床医学2009,3,1:0
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