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| 1 | Summary of Report on Cardiovascular Diseases in China,2012显示文摘The prevalence of cardiovascular diseases(CVDs)is associated with the socioeconomic prosperity,lifestyle changes,accelerated process of ageing and urbanization.The prevalence of CVDs is continuously increasing in China and will remain an upward trend in the next 10 years.CVDs are the leading cause of death for Chinese in both urban area and rural area. | WANG Wen HU Sheng Shou KONG Ling Zhi GAO Run Lin ZHU Man Lu WANG Yong Jun WU Zhao Su CHEN Wei Wei YANG Jin Gang MALi Yuan LIU Ming Bo For the editorial board | 2014 | Biomedical and Environmental Sciences2014，27，7： | 31 |
| 2 | Screening and degrading characteristics and community structure of a high molecular weight polycyclic aromatic hydrocarbon-degrading bacterial consortium from contaminated soil显示文摘Inoculation with effcient microbes had been proved to be the most important way for the bioremediation of polluted environments. For the treatment of abandoned site of Beijing Coking Chemical Plant contaminated with high level of high-molecular-weight polycyclic aromatic hydrocarbons(HMW-PAHs) ,a bacterial consortium capable of degrading HMW-PAHs,designated 1-18-1,was enriched and screened from HMW-PAHs contaminated soil.Its degrading ability was analyzed by high performance liquid chromatography(HPLC) ,and the community structure was investigated by construction and analyses of the 16S rRNA gene clone libraries(A,B and F) at different transfers.The results indicated that 1-18-1 was able to utilize pyrene,fluoranthene and benzoapyrene as sole carbon and energy source for growth.The degradation rate of pyrene and fluoranthene reached 82.8%and 96.2%after incubation for 8 days at 30°C,respectively;while the degradation rate of benzoapyrene was only 65.1%after incubation for 28 days at 30°C. Totally,108,100 and 100 valid clones were randomly selected and sequenced from the libraries A,B,and F.Phylogenetic analyses showed that all the clones could be divided into 5 groups,Bacteroidetes,α-Proteobacteria,Actinobacteria,β-Proteobacteria andγ-Proteobacteria.Sequence similarity analyses showed total 39 operational taxonomic units(OTUs) in the libraries.The predominant bacterial groups wereα-Proteobacteria(19 OTUs,48.7%) ,γ-Proteobacteria(9 OTUs,23.1%) andβ-Proteobacteria(8 OTUs,20.5%) . During the transfer process,the proportions ofα-Proteobacteria andβ-Proteobacteria increased greatly(from 47%to 93%) ,while γ-Proteobacteria decreased from 32%(library A) to 6%(library F) ;and Bacteroidetes group disappeared in libraries B and F. | Run Sun Jinghua Jin Guangdong Sun Ying Liu Zhipei Liu | 2010 | Journal of Environmental Sciences2010，22，10： | 8 |
| 3 | Prognostic Value of NT-proBNP in Stable Coronary Artery Disease in Chinese Patients after Percutaneous Coronary Intervention in the Drug-eluting Stent Era显示文摘Objective The predictive value of N-terminal pro-brain natriuretic peptide(NT-proBNP) in patients with stable coronary artery disease(SCAD) in the drug-eluting stent era is not yet clear. We aimed to evaluate the prognostic value of NT-proBNP in SCAD patients after percutaneous coronary intervention(PCI). Methods We examined 4,293 consecutive SCAD patients who underwent PCI between January 2013 and December 2013 in Fuwai Hospital, China. The primary endpoint was all-cause death. NT-proBNP levels were measured before PCI using Elisa kits(Biomedica, Austria). The indication for PCI was based on the degree of coronary stenosis and evidence of ischemia. Results Among 3,187 SCAD patients with NT-proBNP data, after a 2-year follow-up, NT-proBNP levels were predictive for all-cause death in the SCAD population [area under the receiver operating characteristic curve, 0.768; 95% confidence interval(CI), 0.687-0.849; P < 0.001]. At the optimum cutoff point of 732 pg/mL, the sensitivity and specificity of death was 75.0% and 72.3%, respectively. In a multivariable Cox regression model, the death hazard ratio was 6.43(95% CI, 2.99-13.82; P < 0.001) for patients with NT-proBNP levels ≥ 732 pg/mL, compared with < 732 pg/mL. Conclusion NT-proBNP is a strong predictor of 2-year death with SCAD after PCI in the drug-eluting stent era. | ZHAO Xue Yan LI Jian Xin TANG Xiao Fang XU Jing Jing SONG Ying JIANG Lin CHEN Jue SONG Lei GAO Li Jian GAO Zhan QIAO Shu Bin YANG Yue Jin GAO Run Lin XU Bo YUAN Jin Qing | 2018 | Biomedical and Environmental Sciences2018，31，12： | 5 |
| 4 | Transformation and migration of phosphorus in excess sludge reduction pretreatment by alkaline ferrate oxidation combined with anaerobic digestion显示文摘Recently,more and more attention has been paid to the strong oxidation ability of newly prepared potassium ferrate(NAPF) in sludge reduction process,but less attention has been paid to the change of phosphorus in this process.The feasibility of phosphorus migration and transformation during excess sludge reduction pretre atment using NAPF pre-oxidation combined with anaerobic digestion was investigated.After 70 mg/g suspended solids NAPF pretreatment and 16 days anaerobic digestion,the solid-phase volatile suspended solids decreased by 44.2%,and much organic matter had been released into the liquid-phase and then degraded during digestion by indigenous microorganisms.As the sludge pre-oxidation process was performed,solid-phase organic phosphorus and chemically combined phosphorus also released into the liquid-phase as PO4^3-,peaking at 100 mg/L.During anaerobic digestion,the Fe3+in the liquid-phase was gradually reduced to Fe2+,and then formed Fe^2+-PO4^3- compound crystals and re-migrated to the solid-phase.The concentration of PO4^3- decreased to 17.08± 1.1 mg/L in the liquid-phase after anaerobic digestion.Finally,the phosphorus in the Fe^2+-PO4^3- compound accounts for 80% of the total phosphorus in the solid-phase.A large number of vivianite crystals in sludge were observed.Therefore,this technology not only effectively reduces sludge,but also increases the proportion of PO43-in the sludge in the form of Vivianite. | Xiang Li Yan Yuan Yong Huang Chao-ran Guo Run Jin Ting-ting Liu Jun Ma | 2020 | Journal of Environmental Sciences2020，32，6： | 4 |
| 5 | p-Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular smooth muscle cells显示文摘冠的动脉粥样硬化是长期的肾疾病的主要复杂并发症。这个条件在分离病人贡献增加的死亡。p-Cresyl 硫酸盐(PCS ) 是蛋白质界限的一个原型不能高效地通过平淡的分离过程被移开的尿毒症的毒素。在现在的学习,也就是,经历了 5/6 肾切除术的 ApoE -/- 老鼠随机被划分成二个组对待车辆的组(n = 20 ) 并且对待 PCS 的组(n = 20 ) 。老鼠被牺牲为在在高脂肪的饮食的 8 或 24 个星期以后的脸和 immunohistological 分析。老鼠大动脉的脉管的光滑的肌肉房间(VSMC ) 与的磷酸盐缓冲区答案或 500 mol/L PCS 被对待在 vitro 评估。对待 PCS 的老鼠被观察在八星期 PCS 管理以后承受增加的动脉粥样硬化患者损害。而且, 24 星期 PCS 管理显著地也增加了大动脉的匾的危险索引。PCS 也被观察在疾病的前进期间便于 VSMC 的迁居和增长。而且, PCS 在匾以内扰乱了在矩阵 metalloproteinases 和 metalloproteinases 的织物禁止者之间的平衡。因此, PCS 在支持 atherogenesis 并且由指向 VSMC 可能扰乱形成的匾的稳定性起了一个重要作用。 | Hui Han Yanjia Chen Zhengbin Zhu Xiuxiu Su Jingwei Ni Run Du Ruiyan Zhang Wei Jin | 2016 | Frontiers of Medicine2016，10，3： | 3 |
| 6 | Association of CDKN2B-AS1 Polymorphisms with Premature Triple-vessel Coronary Disease and Their Sex Specificity in the Chinese Population显示文摘Objective The aim of this study is to establish whether cyclin-dependent kinase inhibitor 2B antisense RNA 1(CDKN2 B-AS1) gene polymorphisms are associated with premature triple-vessel disease(PTVD). Methods Nine single-nucleotide polymorphisms(rs1063192, rs10757274, rs1333042, rs1333049, rs2285327, rs3217986, rs3217992, rs4977574, and rs9632884) were genotyped in 884 PTVD patients and 907 control subjects(males ≤ 50 years old and females ≤ 60 years old) using the improved multiplex ligase detection reaction method. Results The allele frequencies of rs10757274 G, rs1333049 C, rs4977574 G(all P < 0.001), and rs3217986 G(P = 0.040) were significantly higher in the PTVD group than in the control group, but those of rs1063192 A, rs1333042 G, and rs9632884 C(all P < 0.001) were significantly lower in the former than in the latter. Logistic regression analysis revealed that homozygote AA of rs1333042 is associated with decreased risk for PTVD(OR = 0.42, 95% CI: 0.22-0.82, P = 0.011). In addition, the allele frequencies observed differed between genders. The G allele of rs3217986 was associated with increased risk for PTVD in male patients only(OR = 2.94, 95% CI: 1.27-6.80, P = 0.012) in the dominant model, and no positively mutated allele was found in female patients. Conclusion Polymorphisms of the CDKN2 B-AS1 gene are associated with the incidence of PTVD in the Chinese population. Furthermore, the frequencies of mutated alleles differed between genders. | XU Jing Jing JIANG Lin XU Lian Jun GAO Zhan ZHAO Xue Yan ZHANG Yin SONG Ying LIU Ru SUN Kai GAO Run Lin XU Bo SONG Lei YUAN Jin Qing | 2018 | Biomedical and Environmental Sciences2018，31，11： | 3 |
| 7 | Elevated-temperature tribological behavior of Ti–B–C–N coatings deposited by reactive magnetron sputtering显示文摘Quaternary Ti-B-C-N coatings with various carbon contents were deposited on high-speed steel(HSS)substrates by reactive magnetron sputtering(RMS) system.The elevated-temperature tribological behavior of Ti-BC-N coatings was explored using pin-on-disk tribometer,scanning electron microscopy(SEM),and energy-dispersive X-ray spectroscopy(EDX).The present results show that the steady-state friction coefficient value and the instantaneous friction coefficient fluctuation range of TiB-C-N coatings decrease as carbon content increases at100 and 300 ℃,while the steady-state friction coefficient value of all Ti-B-C-N coatings becomes higher than 0.4 at500 ℃.As ambient temperature increases,the running-in periods of all Ti-B-C-N coatings become shorter.Wear damage to Ti-B-C-N coatings during sliding at elevated temperature is mainly caused by adhesive wear,and adhesive-wear damage to Ti-B-C-N coatings increases as ambient temperature increases;however,higher carbon content is beneficial for decreasing the adhesive-wear damage to Ti-B-C-N coatings during sliding at elevated temperature. | Xiang-Yang Chen Shao-Fu Huang Sheng-Li Ma Run Huang Jin Zhang Hai-Xia Hu | 2015 | Rare Metals2015，34，12： | 2 |
| 8 | Risk or Beneficial Factors Associated with Unplanned Revascularization Risk Following Percutaneous Coronary Intervention: A Large Single-Center Data显示文摘Objective To analyze factors associated with unplanned revascularization(UR) risk in patients with coronary artery disease(CAD) who underwent percutaneous coronary intervention(PCI).Methods A total of 10,640 cases with CAD who underwent PCI were analyzed. Multivariate COX regressions and competing risk regressions were applied.Results The patients who underwent UR following PCI in 30 days, 1, and 2 years accounted for 0.3%,6.5%, and 8.7%, respectively. After multivariate adjustment, the number of target lesions [hazard ratio(HR) = 2.320;95% confidence interval(CI): 1.643–3.277;P < 0.001], time of procedure(HR = 1.006;95%CI: 1.001–1.010;P = 0.014), body mass index(HR = 1.104;95% CI: 1.006–1.210;P = 0.036), incomplete revascularization(ICR)(HR = 2.476;95% CI: 1.030–5.952;P = 0.043), and age(HR = 1.037;95% CI:1.000–1.075;P = 0.048) were determined as independent risk factors of 30-day UR. Factors, including low-molecular-weight heparin or fondaparinux(HR = 0.618;95% CI: 0.531–0.719;P < 0.001), secondgeneration durable polymer drug-eluting stent(HR = 0.713;95% CI: 0.624–0.814;P < 0.001), left anterior descending artery involvement(HR = 0.654;95% CI: 0.530–0.807;P < 0.001), and age(HR = 0.992;95%CI: 0.985–0.998;P = 0.014), were independently associated with decreased two-year UR risk. While,Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery score(HR =1.024;95% CI: 1.014–1.033;P < 0.001) and ICR(HR = 1.549;95% CI: 1.290–1.860;P < 0.001) were negatively associated with two-year UR risk.Conclusion Specific factors were positively or negatively associated with short-and medium-long-term UR following PCI. | LIU Ru GAO Zhan GAO Li Jian ZHAO Xue Yan CHEN Jue QIAO Shu Bin YANG Yue Jin GAO Run Lin XU Bo YUAN Jin Qing | 2020 | Biomedical and Environmental Sciences2020，33，6： | 2 |
| 9 | Splenic littoral cell hemangioendothelioma: Report of a case with hepatic metastases and review of the literature显示文摘 | Ping He Xi‐De Yan Jin‐Rui Wang Run‐Cai Guo Hua‐Bin Zhang | 2014 | Ultrasound2014，，5： | 2 |
| 10 | Long‐term outcomes of complete versus incomplete revascularization after drug‐eluting stent implantation in patients with multivessel coronary disease显示文摘 | Zhan Gao Bo Xu Yue‐jin Yang Jin‐qing Yuan Jue Chen Ji‐lin Chen Shu‐bin Qiao Yong‐jian Wu Hong‐bin Yan Run‐lin Gao | 2013 | Intervent2013，，3： | 1 |
| 11 | Designated Cloud Server Public Key Encryption with Keyword Search from Lattice in the Standard Model显示文摘Recently, how to retrieve the encrypted data efficiently from a cloud storage system becomes a hot topic. Public key encryption with keyword search(PEKS)can allow one to search the encrypted data with a keyword efficiently. Due to the booming of post-quantum cryptography, we propose public key encryption with keyword search from lattice assumption, which can resist quantum computer attacks. We delegate a particular cloud server to search the results, thus only the designated cloud server can finish the test process. Our scheme has been proved ciphertext indistinguishability in the standard model, which can reflect its security in the real world. To the best of our knowledge, our scheme is the first construction based on lattice in the standard model, which is a step stone in the post-quantum cryptographic communication. | ZHANG Xiaojun XU Chunxiang XIE Run JIN Chunhua | 2018 | Chinese Journal of Electronics2018，27，2： | 1 |
| 12 | Jordan Semi-Triple Multiplicative Maps on the Hermitian Matrices显示文摘In this paper,we show that every injective Jordan semi-triple multiplicative map on the Hermitian matrices must be surjective,and hence is a Jordan ring isomorphism. | Si Qing YAN Run Ling AN Jin Chuan HOU | 2011 | Journal of Mathematical Research and Exposition2011，31，6： | 1 |
| 13 | A Characterization of *-Automorphism on B(H)显示文摘<正> Let H be a Hilbert space and ■ be a standard *-subalgebra of B(H). We show that abijective map φ: ■→■ preserves the Lie-skew product AB - BA~* if and only if there is a unitaryor conjugate unitary operator U ■B(H) such that φ(A) = UAU~* for all A∈■ , that is, φ is a linear*-isomorphism or a conjugate linear *-isomorphism. | Run Ling AN Jin Chuan HOU | 2010 | Acta Mathematica Sinica,English Series2010，26，2： | 1 |
| 14 | SARS Patients-derived Human Recombinant Antibodies to S and M Proteins Efficiently Neutralize SARS-Coronavirus Infectivity显示文摘Objective To develop a specific SARS virus-targeted antibody preparation for emergent prophylaxis and treatment of SARS virus infection. Methods By using phage display technology, we constructed a naive antibody library from convalescent SARS patient lymphocytes. To obtain the neutralizing antibody to SARS virus surface proteins, the library panning procedure was performed on purified SARS virions and the specific Fab antibody clones were enriched by four rounds of repeated panning procedure and screened by highthroughput selection. The selected Fab antibodies expressed in the periplasma of E. Coli were soluble and further purified and tested for their binding properties and antiviral function to SARS virus. The functional Fab antibodies were converted to full human IgG antibodies with recombinant baculovirus/insect cell systems and their neutralizing activities were further determined. Results After four rounds of the panning, a number of SARS-CoV virus-targeted human recombinant Fab antibodies were isolated from the SARS patient antibody library. Most of these were identified to recognize both natural and recombinant SARS spike (S) proteins, two Fab antibodies were specific for the virus membrane (M) protein, only one bound to SARS-CoV nucleocapsid protein. The SARS-CoV S and M protein-targeted Fab or IgG antibodies showed significant neutralizing activities in cytopathic effect (CPE) inhibition neutralization test, these antibodies were able to completely neutralize the SARS virus and protect the Vero cells from CPE after virus infection. However, the N protein-targeted Fab or IgG antibodies failed to neutralize the virus. In addition, the SARS N protein-targeted human Fab antibody reacted with the denatured N proteins, whereas none of the S and M protein specific neutralizing antibodies did. These results suggested that the S and M protein-specific neutralizing antibodies could recognize conformational epitopes which might be involved in the binding of virions to cellular receptors and the fusion activity of the virus.Conclusion The SARS-CoV spike protein and membrane proteins are able to elicite efficient neutralizing antibodies in SARS patients. The neutralizing antibodies we generated in this study may be more promising candidates for prophylaxis and treatment of SARS infection. | MI-FANG LIANG RUN -LEI DU JING-ZHI LIU CHUAN LI QUAN-FU ZHANG LU-LU HAN JIAN-SHI YU SHU-MIN DUAN XIAO-FANG WANG KONG-XING WU ZHAO-HUI XION QI JIN DE-XIN LI | 2005 | Biomedical and Environmental Sciences2005，18，6： | 1 |
| 15 | Esti-mating risk of foreign exchange portfolio:Using VaR and CVaR basedon GARCH-EVT-Copula model 显示文摘 | Zong Run Wang Xiao Hong Chen Yan Bo Jin Yan Ju Zhou | 2010 | Physica A2010，，389： | 1 |
| 16 | Efficient forward secure identity-based shorter signature from lattice显示文摘 | Xiaojun Zhang Chunxiang Xu Chunhua Jin Run Xie | 2013 | Computers and Electrical Engineering2013，，： | 1 |
| 17 | Does Percutaneous Coronary Intervention on Off Days have an Effect on Long-term Prognosis in Patients with Coronary Artery Disease in China?显示文摘As generally known,many hospitals provide routine care on weekdays but only emergency or urgent care on holidays and weekends.Hospital staffing is numerically reduced on holidays and weekends,as well as the available expertise on duty.The onset of acute myocardial infarction (AMI) on off days was reported to be associated with higher short-term mortality[1,2]. | LIU Ru GAO Li Jian XU Ou ZHANG Ce JIA Si Da QIAO Shu Bin YANG Yue Jin GAO Run Lin XU Bo YUAN Jin Qing | 2021 | Biomedical and Environmental Sciences2021，34，5： | 1 |
| 18 | VEGF-induced neuroprotection, neurogenesis and angiogenesis after focal cerebral ischemia 显示文摘 | Run Y Jin K Xie L | 2003 | J Clin Invest2003，111，12： | 1 |
| 19 | Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation显示文摘 | Cao Jin Lin Lu Zheng Bin Zhu Rui Yan Zhang Qi Zhang Run Du Feng Hua Ding Qiu Jing Chen Wei Feng Shen | 2010 | Coronary Artery Disease2010，，5： | 1 |
| 20 | Burst strain disturbance—A new test study on fracture precursor显示文摘IntroductionBeforeanearthquakeocuurs,deformationvariationsobviouslyappearinseismogenicareaandnearbywhichwerereportedalot.Earl... | ZHAO YONG XU 1) RUN HAI YANG 1) BIN WANG 1) JIN MING ZHAO 1) YU FENG YAO 1) PEI ZHONG HUA 1) SHI RONG MEI 2) 1) Seismological Bureau of Yunnan Province, Kunming, 650041, China 2) Center for Analysi | 1998 | Acta Seismologica Sinica(English Edition)1998，11，6： | 1 |
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