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| 1 | Waxy allelic diversity in common millet(Panicum miliaceum L.) in China显示文摘A set of 132 accessions of common millet,Panicum miliaceum L.,from 12 provinces of China were assessed for endosperm starch type(waxy or non-waxy)using I_2-KI staining,amylose and amylopectin contents using the dual-wavelength colorimetric method,and genotype of Waxy genes conditioning amylose content by gene sequencing.Endosperm starch content varied from57.69%to 74.70%,while the amylose and amylopectin contents of the starch ranged from 0 to23.29%and from 41.99%to 70.24%,respectively.Sequencing two Wx genes,including Wx-L(intron 5-exon 7 and intron 8–9)and Wx-S(exon 9–intron 10)revealed several polymorphisms(S_0,S_(-15),L_C,L_F,L_Y).Marker M5-R11 linking to the Wx-S gene may be used to discriminate waxy common millet accessions from non-waxy ones.Among the 132 accessions,68 with the S_(-15)allele had waxy endosperm starch with the amylose content range 0–2.58%and 64 accessions with the S_0allele had non-waxy endosperm starch with amylose content range 3.94%–23.29%.Five genotypes including S_(-15)/L_F(45%of the accessions),S_0/L_F(25%),S_0/L_Y(12%),S_0/L_C(11%),and S_(-15)/L_Y(7%)were identified.Six new SNPs were detected at the Wx-L locus.These results will facilitate common millet breeding,especially of cultivars free of amylose. | Ruiyun Wang Haigang Wang Xiaohuan Liu Xu Ji Ling Chen Ping Lu Minxuan Liu Bin Teng Zhijun Qiao | 2018 | The Crop Journal2018，6，4： | 10 |
| 2 | Efficient lung cancer-targeted drug delivery via a nanoparticle/MSC system显示文摘Low targeting efficiency limits the applications of nanoparticles in cancer therapy. The fact that mesenchymal stem cells(MSC) trapped in the lung after systemic infusion is a disadvantage for cell therapy purposes. Here, we utilized MSC as lung cancer-targeted drug delivery vehicles by loading nanoparticles(NP)with anti-cancer drug. MSC showed a higher drug intake capacity than fibroblasts. In addition, MSC showed predominant lung trapping in both rabbit and monkey. IR-780 dye, a fluorescent probe used to represent docetaxel(DTX) in NP, delivered via MSC accumulated in the lung. Both in vitro MSC/A549 cell experiments and in vivo MSC/lung cancer experiments validated the intercellular transportation of NP between MSC and cancer cells. In vivo assays showed that the MSC/NP/DTX drug delivery system exerted primary tumor inhibition efficiency similar to that of a NP/DTX drug system. Collectively, the MSC/NP drug delivery system is promising for lung-targeted drug delivery for the treatment of lung cancer and other lung-related diseases. | Xusheng Wang Haiyan Chen Xiaowei Zeng Wenpeng Guo Yu Jin Shan Wang Ruiyun Tian Yanjiang Han Ling Guo Jimin Han Yaojiong Wu Lin Mei | 2019 | Acta Pharmaceutica Sinica B2019，9，1： | 4 |
| 3 | Improved quantum ant colony algorithm based on bloch coordinatcs显示文摘 | Chen Xiaofeng Xia Xingyou Yu Ruiyun | 2013 | Journal of Computers:Finland2013，8，6： | 1 |
| 4 | Activation of Notch1 signaling by marrow-derived mesenchymal stem cells through cell–cell contact inhibits proliferation of hepatic stellate cells显示文摘 | Si Chen linan Xu Nan Lin Weidong Pan Kunpeng Hu Ruiyun Xu | 2011 | Life Sciences2011，，25： | 1 |
| 5 | Recovery of metal values from copper smelter flue dust显示文摘 | KE Jiajun QIN Ruiyun CHEN Chiyang | 2012 | Hydrometallurgy2012，12，2： | 1 |
| 6 | Hypoxia-induced secretion of platelet-derived growth factor?BB by hepatocellularcarcinoma cells increases activated hepatic stellate cell proliferation, migrationand expression of vascular endothelial growth factor?A显示文摘 | Yi Lu Nan Lin Zhiju Chen Ruiyun Xu | 2015 | Molecular Medicine Reports2015，，1： | 1 |
| 7 | Recovery of Metal Values From Copper Smelter Flue Dust显示文摘 | Ke Jiajun Qin Ruiyun Chen Chiyang | 1984 | Hydrometallurgy1984，12，2： | 1 |
| 8 | Improved Quantum Ant Colony Algorithm based on Bloch Coordinates显示文摘 | Xiaofeng Chen Xingyou Xia Ruiyun Yu | 2013 | Journal of Computers2013，，6： | 1 |
| 9 | The role of surface charges in the blinking mechanisms and quantum-confined Stark effect of single colloidal quantum dots显示文摘The two frequently observed phenomena,photoluminescence(PL)blinking and quantum-confined Stark effect(QCSE)-induced spectral diffusion,are not conducive to the applications of colloidal quantum dots(QDs).It remains elusive how these two phenomena are linked to each other.Unraveling the potential link between blinking and QCSE could facilitate the adoption of appropriate strategies that can simultaneously suppress both PL blinking and spectral diffusion.In this work,we investigated the blinking mechanism and QCSE of single CdSe/CdS/ZnS QDs in the presence of positive and negative surface charges using single-dot PL spectroscopy.We found that the negative surface charges can simultaneously suppress PL blinking and spectral diffusion of single QDs.On the other hand,the positive surface charges could change the blinking mechanisms of QDs from Auger-blinking to band-edge carrier(BC)-blinking.Two types of QCSE were observed,and a significant QCSE-induced spectral broadening of 5.25 nm was measured,which could be attributed to the hopping of surface charges between different surface-trap sites.Based on these findings,several theoretical models are proposed to explain various phenomena observed. | Jialu Li Dengfeng Wang Guofeng Zhang Changgang Yang Wenli Guo Xue Han Xiuqing Bai Ruiyun Chen Chengbing Qin Jianyong Hu Liantuan Xiao Suotang Jia | 2022 | Nano Research2022，15，8： | 0 |
| 10 | Structure Identification for Force-Induced Reaction Using Single-Molecule Conductance Measurement显示文摘Spiropyran derivatives are prototype mechanophores with a promising application as molecular sensors because of their changeable structure under external force stimuli.However,the chemical structure evolution under external stimuli remains unclear due to the uncertainty and difficulty in distinguishing the structures of different ring-opened merocyanine isomers generated in the force-induced reaction.Here we identify the structure of isomers produced by the force-induced reaction of spiropyran derivatives using a single-molecule conductance measurement and an unsupervised clustering algorithm.We found that the original data from the single-molecule conductance measurement can be divided into four clusters through unsupervised clustering.By introducing a photoinduced reaction and theoretical calculation,we identified and attributed the four clusters of data to the multiple states of the molecular junctions.Our work demonstrates that a single-molecule break junction measurement can distinguish the isomers in the force-induced reaction,suggesting the great potential of single-molecule conductance measurement and unsupervised clustering approaches for structural analysis. | Jueting Zheng Wenli Gao Taige Lu Lijue Chen Luchun Lin Ruiyun Huang Yongxiang Tang Gang Dong Junyang Liu Yifei Pan Wengui Weng Wenjing Hong | 2023 | CCS Chemistry2023，5，8： | 0 |
| 11 | Tunable microfluidic chip for single-cell deformation study显示文摘Microfluidic phenotyping methods have been of vital importance for cellular characterization,especially for evaluating single cells.In order to study the deformability of a single cell,we devised and tested a tunable microfluidic chip-based method.A pneumatic polymer polydimethylsiloxane(PDMS)membrane was designed and fabricated abutting a single-cell trapping structure,so the cell could be squeezed controllably in a lateral direction.Cell contour changes under increasing pressure were recorded,enabling the deformation degree of different types of single cell to be analyzed and compared using computer vision.This provides a new perspective for studying mechanical properties of cells at the single cell level. | Ruiyun Zhang Xuexin Duan Shuaihua Zhang Wenlan Guo Chen Sun Ziyu Han | 2023 | Nanotechnology and Precision Engineering2023，6，2： | 0 |
| 12 | Artificial intelligence algorithms for cyberspace security applications:a technological and status review显示文摘Three technical problems should be solved urgently in cyberspace security:the timeliness and accuracy of network attack detection,the credibility assessment and prediction of the security situation,and the effectiveness of security defense strategy optimization.Artificial intelligence(AI)algorithms have become the core means to increase the chance of security and improve the network attack and defense ability in the application of cyberspace security.Recently,the breakthrough and application of AI technology have provided a series of advanced approaches for further enhancing network defense ability.This work presents a comprehensive review of AI technology articles for cyberspace security applications,mainly from 2017 to 2022.The papers are selected from a variety of journals and conferences:52.68%are from Elsevier,Springer,and IEEE journals and 25%are from international conferences.With a specific focus on the latest approaches in machine learning(ML),deep learning(DL),and some popular optimization algorithms,the characteristics of the algorithmic models,performance results,datasets,potential benefits,and limitations are analyzed,and some of the existing challenges are highlighted.This work is intended to provide technical guidance for researchers who would like to obtain the potential of AI technical methods for cyberspace security and to provide tips for the later resolution of specific cyberspace security issues,and a mastery of the current development trends of technology and application and hot issues in the field of network security.It also indicates certain existing challenges and gives directions for addressing them effectively. | Jie CHEN Dandan WU Ruiyun XIE | 2023 | Frontiers of Information Technology & Electronic Engineering2023，24，8： | 0 |
| 13 | Study on the distribution characteristics of faults and their control over petroliferous basins in the China seas and its adjacent areas显示文摘As one of the main controlling factors of oil and gas accumulation,faults are closely related to the distribution of oil and gas reservoirs.Studying how faults control petroliferous basins is particularly important.In this work,we investigated the plane positions of major faults in the China seas and its adjacent areas using the normalized vertical derivative of the total horizontal derivative(NVDR-THDR)of the Bouguer gravity anomaly,the fusion results of gravity and magnetic anomalies,and the residual Bouguer gravity anomaly.The apparent depths of major faults in the China seas and its adjacent areas were inverted using the Tilt-Euler method based on the Bouguer gravity anomaly.The results show that the strikes of the faults in the China seas and its adjacent areas are mainly NE and NW,followed by EW,and near-SN.Among them,the lengths of most ultra-crustal faults are in the range of 1000–3000 km,and their apparent depths lie between 10 km and 40 km.The lengths of crustal faults lie between 300 km and 1000 km,and their apparent depths are between 0 km and 20 km.According to the plane positions and apparent depths of the faults,we put forward the concept of fault influence factor for the first time.Based on this factor,the key areas for oil and gas exploration were found as follows:the east of South North China Basin in the intracontinental rift basins;the southeast region of East China Sea Shelf Basin,the Taixinan and Qiongdongnan basins in the continental margin rift basins;Zhongjiannan Basin in the strike-slip pull-apart basins;the Liyue,Beikang,and the Nanweixi basins in the rifted continental basins.This work provides valuable insights into oil and gas exploration,mineral resource exploration,and deep geological structure research in the China seas and its adjacent areas. | Xin’gang Luo Wanyin Wang Ying Chen Zhizhao Bai Dingding Wang Tao He Yimi Zhang Ruiyun Ma | 2023 | Acta Oceanologica Sinica2023，42，3： | 0 |
| 14 | Electric field-driven folding of single molecules显示文摘Folding of molecules is an essential process in nature,and various molecular machines achieve their chemical and mechanical function via controlled folding of molecular conformations.The electric field offers a unique strategy to drive the folding of molecular conformation and to control charge transport through single molecules but remains unexplored.The single-molecule break junction technique provides access to detect the conformational changes via the monitoring of single-molecule conductance,and the electric field between two metal electrodes with nanoscale spacing can provide an extremely strong to achieve in-situ control and detection of molecular folding at the single-molecule level.Here,we use the electric field to control the single-molecule folding using the scanning tunneling microscope break junction(STM-BJ)technique.The electric fields induced folding could lead to a∼1400%conductance change of the single-molecule junctions,and the folding/unfolding process can be in-situ switched at the scale of milliseconds.DFT calculations suggest the conformational control originates from the electric fieldinduced charge injection,and the formation of homoconjugated conformation with the overlapped orbitals.This work provides the first demonstration of electric field-driven molecular folding,which is essential for the understanding of molecular machines in nature and for the design of artificial molecular machines. | Saisai Yuan Yu Zhou Tengyang Gao Lichuan Chen Wei Xu Ping Duan Juejun Wang Zhichao Pan Chun Tang Yang Yang Ruiyun Huang Zongyuan Xiao Wenjing Hong | 2024 | Chinese Chemical Letters2024，35，1： | 0 |
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