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39篇 您的检索式：作者名="Robert CG"

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	题名	作者	年代	出处	被引量
1	Chemoprotective effects of curcumin in esophageal epithelial cells exposed to bile acids显示文摘AIM:To investigate the ability of curcumin to counteract the impact of bile acids on gene expression of esophageal epithelial cells.METHODS:An esophageal epithelial cell line(HET1A)was treated with curcumin in the presence of deoxycholic acid.Cell proliferation and viability assays were used to establish an appropriate dose range for curcumin.The combined and individual effects of curcumin and bile acid on cyclooxygenase-2(COX-2)and superoxide dismutase(SOD-1 and SOD-2)gene expression were also assessed.RESULTS:Curcumin in a dose range of 10-100μmol/L displayed minimal inhibition of HET-1A cell viability.Deoxycholic acid at a concentration of 200μmol/L caused a 2.4-fold increase in COX-2 gene expression compared to vehicle control.The increased expression of COX-2 induced by deoxycholic acid was partially reversed by the addition of curcumin,and curcumin reduced COX-2 expression 3.3-to 1.3-fold.HET-1A cells exposed to bile acid yielded reduced expression of SOD-1 and SOD-2 genes with the exception that high dose deoxycholic acid at 200μmol/L led to a 3-fold increase in SOD-2 expression.The addition of curcumin treatment partially reversed the bile acid-induced reduction in SOD-1 expression at all concentrations of curcumin tested.CONCLUSION:Curcumin reverses bile acid suppression of gene expression of SOD-1.Curcumin is also able to inhibit bile acid induction of COX-2 gene expression.	Matthew R Bower Harini S Aiyer Robert CG Martin Yan Li	2010	World Journal of Gastroenterology2010，16，33：	10
2	Hypothyroidism显示文摘	Roberts CG Ladenson PW	2004	Lancet2004，363，9411：	1
3	Hypothyroidism显示文摘	Roberts CG Ladenson PW	2004	Lancet2004，363，9411：	1
4	Hypothyroidism 显示文摘	Roberts CG Ladenson PW	2004	Lancet2004，363，：	1
5	Efficacy and safety of statin monotherapy in older adults:a meta-analysis显示文摘	Roberts CG Guallar E Rodriguez A	2007	J Gerontol A Biol Sci Med Sci2007，62，8：	1
6	Hypothyroidism显示文摘	Roberts CG Ladeuson PW	2004	Lancet2004，363，：	1
7	A simple fluoroscopic approach to percutaneous transgastric cystgastmstomy with internalized drainage catheter for treatment of pancreatic pseudocysts: Report of two cases显示文摘	Ron CG Sandra JM Robert KR	2010	Digestive Diseases and Sciences2010，55，2：	1
8	Studies on the bioburden on medical devices and the importance of cleaning显示文摘	Robert CG	2001	Infect Control Hosp Epidemiol2001，22，1：	1
9	Risk factors for intra- abdominal hypertension and abdominal compartment syn- drome among adult intensive care unit patients: a systematic re- view and meta- analysis显示文摘	Holodinsky JK Roberts D J Ball CG	2013	Crit Care2013，17，5：	1
10	Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast canc- er cells and predicts patient outeome and tarnoxifen responsiveness in breast cancer显示文摘	Roberts CG	2011	Oncogene2011，30，28：	1
11	Energy subtraction digital radiography technical considerations,clinical applications,and imaging pitfalls显示文摘	Robert CG Peter B Sachs D	2006	Thorac Imaging2006，21，4：	1
12	Variants in scavenger receptor class B type I gene are associated with HDL cholesterol levels in younger women 显示文摘	Roberts CG Shen H Mitchell BD	2007	Hum Hered2007，64，2：	1
13	the role of re-altime scanning in antenatal fetalsurreillance显示文摘	Vilang B Robert CG Trudinger BJ	2008	Am JObstet Gynecol2008，140，：	1
14	Solid-pseudopapillary tumor of the pancreas a surgical enigma显示文摘	Robert CG Mantin MD David S	2002	Ann Surg Oncol2002，9，：	1
15	Characterization of natural-显示文摘	Dall KL Scarpini CG Roberts I	2008	Cancer Res2008，68，20：	1
16	Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer 显示文摘	Roberts CG Millar EK O'Toole SA	2011	Oncogene2011，30，28：	1
17	the role of realtime scanning in antenatal fetalsurreillance显示文摘	Vilang B Robert CG Trudinger BJ	1981	Am J Obstet Gynecol1981，140，：	1
18	Leucocyte analysis using monoclonal antibodies in human glomerulonephritis显示文摘	David HH David CG Robert CA	1987	Kidney Int1987，31，4：	1
19	Omega - 3 polyunsaturated fatty acids in the treatment of kidney disease 显示文摘	Robert G Fassett Glenda CG	2010	American J Kidney Disease2010，56，4：	1
20	A novel, sensitive detection system for high-density microarrays using dendrimer technology 显示文摘	Robert CG Steven RG	2000	Physiol Genomics2000，3，2：	1

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