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| 1 | Current medical management of endocrine-related male infertility显示文摘男因素贡献全面不孕的 50%-60% ,但是是完全负责的在仅仅 20% 夫妇。尽管很男的因素不孕从反常精液分析被查明,如果样品归还正常,另外的男因素能特别是贡献的。男不孕能由于可能可逆或不可逆的可看作是相同的神经质或解剖的病原学。这张手稿将包括多种维生素,雌激素受体调节的人(clomiphene ) ,雌激素变换 blockers (anastrozole ) ,和荷尔蒙代替为男不孕和实验治疗为荷尔蒙评估加亮存在指南和我们的建议。 | Joshua D Ring Aye A Lwin Tobias S Kohler | 2016 | Asian Journal of Andrology2016，18，3： | 12 |
| 2 | Chemical conjugation of a novel antibody interleukin 2 immunoconjugate against c erbB 2 product显示文摘Objective To develop a new chemical method to produce a monoclonal antibody (MoAb) 520C9/recombinant human interleukin 2 (rhIL 2) conjugate Methods MoAb 520C9 reactive with the protooncogene c erbB 2 product P185 was chemically conjugated with rhIL 2 by using a simple two step method First, the rhIL 2 was activated by Sulfosuccinimidyl 4 [N maleimidomethyl] cyclohexane 1 carboxylate, a heterobifunctional linker, and N succinimidyl s acetylthioacetate was introduced onto 520C9 Then SATA on the 520C9 was reacted with the maleimide group on the activated rhIL 2 to generate 520C9 rhIL 2 immunoconjugate Results The immunoconjugate retained the antigen binding activity compared to the respective native antibody as determined by an indirect live cell binding assay The immunoconjugate also possessed IL 2 activity as measured by the standard CTLL 2 cells proliferation assay and the stimulation of human peripheral blood mononuclear cells (PBMCs) into lymphokine activated killer cells Conclusion Our method of conjugation of rhIL 2 to 520C9 preserves the binding activity of the antibody and the cytokine function of IL 2 This simple and efficient method of conjugation should be applicable to other types of MoAbs and recombinant | 李君 Sharon E Lee Marie Belciug David B Ring Cheuk S Kwok | 2000 | Chinese Medical Journal2000，，2： | 3 |
| 3 | Stiff tests for designer starches显示文摘 | Ring S G | 1995 | Chem Brit1995，，4： | 2 |
| 4 | Efficacy and Safety Comparison of Liraglutide, Glimepiride, and Placebo, All in Combination With Metformin, in Type 2 Diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study显示文摘 | Nauck Michael Frid Anders Hermansen Kjeld Shah Nalini S Tankova Tsvetalina Mitha Ismail H Zdravkovic Milan Düring Maria Matthews David R | 2009 | Diabetes Care2009，，： | 2 |
| 5 | Further characterization of the expression in liver and catalytic activity of CYP 26B显示文摘 | Ekins S VandenBranden M Ring BJ | 1998 | J Pharmacol Exp Ther1998，266，： | 1 |
| 6 | Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations 显示文摘 | Mahnel R Kalt A Ring S | 2005 | Am J Gastroenterol2005，100，： | 1 |
| 7 | Structuring cooperative relationships between organizations显示文摘 | Ring P S A H Van De Ven | 1992 | Strategic Management Journal1992，7，13： | 1 |
| 8 | REDIA-impacts of DRG introduction in the acute sector on medical rehabih'tation显示文摘 | von Eif W Sch ii ring S Greitemann B | 2011 | Die Rehabilitation2011，50，4： | 1 |
| 9 | Tolerogenic dendritic cells and regulatory T cells: A two-way relationship显示文摘 | Mahnke K Johnson TS Ring S | 2007 | Journal of Dermatological Science2007，46，3： | 1 |
| 10 | In vivo expression of RANKL in the rat dental follicle as determined by laser capture microdlssection 显示文摘 | Yao S Ring S Henk WG | 2004 | Arch Oral Biol2004，49，6： | 1 |
| 11 | Developmental processes of cooperative inter organizational relationships 显示文摘 | Ring P S Van de Ven A H | 1994 | Academy of Management Review1994，19，1： | 1 |
| 12 | Relational Quality:Management Trust in Corporate Alliances显示文摘 | ARINO A TORRE J RING P S | 2001 | California Management Review2001，44，1： | 1 |
| 13 | Development of a biochemotherapy regimen with concurrent,administration of cisplation,vinblastine,dacarbazine,interferon alfa,and interleukin-2 for patients with metastatic melanoma显示文摘 | Legha SS Ring S Eton O | 1998 | J Clin Oncol1998，16，5： | 1 |
| 14 | Simple modeling of Donnan separation processes 显示文摘 | RING S HASSON D SHEMER H | 2015 | Journal of Membrane Science2015，476，： | 1 |
| 15 | Some studies on starch gelation显示文摘 | Ring S G | 1985 | Starch1985，37，2： | 1 |
| 16 | Systemically and topi2cally administered leptin both accelerate wound healing in diabetic ob/ob mice显示文摘 | Ring B D Scully S Davis C R | 2000 | Endocrinology2000，141，： | 1 |
| 17 | celalim of amylose显示文摘 | Miles M J Morri V J Ring S G | 1985 | Carbohydrate Research1985，135，2： | 1 |
| 18 | Tolerogenic dendritic cells and regulatory T cells:a two-way relationship 显示文摘 | Mahnke K Johnson T S Ring S | 2007 | J Dermatol Sci2007，46，3： | 1 |
| 19 | The gelatin and cstallisation of amylopeclin 显示文摘 | Ring S G Cohmna P Kenneih J | 1987 | Carbohydrate Research1987，162，2： | 1 |
| 20 | Immediate-early transactivator Rta of Epstein-Barr virus (EBV) shows multiple epitopes recognized by EBV-specific cytotoxic T lymphocytes 显示文摘 | Pepperl S Benninger-D?ring G Modrow S | 1998 | J Virol1998，72，11： | 1 |
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