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| 1 | Immune response to an indigenously developed r-Hepatitis B vaccine in mixed population: Study of an accelerated vaccination schedule显示文摘AIM: To establish the safety and efficacy of an indigenously developed r-hepatitis B vaccine using an accelerated schedule and to highlight the social awareness and commitment in preventing the spreading of hepatitis B virus infection.METHODS: The study was a multicentric, double blind,randomized (3:1) study using three doses of vaccine immunization schedule (20 μg for those above 10 years old and 10 μg for those below 10 years old) on d 0, 30and 60. One hundred and sixty-six subjects were enrolled(87 males and 76 females aged 5-35 years). The main outcome measure was assessment of immunogenicity and safety.RESULTS: A 100% seroconversion response was observed on the 30th d after the 1st injection in both the experimental groups. The sero-protection data reported a 41.2-65.6% response on the 30th d after the 1st injection and reached 100% on the 60th d. Descriptive statical analysis showed a geometric mean titer value of 13.77 mIU/mL in the test (BEVAC) group and 10.95 mIU/mL in the commercial control (ENGERIX-B) group on the 30th d after the 1st injection. The response on the 60th d showed a geometric mean titre value (GMT) of 519.84 mIU/mL in the BEVAC group and 475.46 mIU/mL in the ENGERIX-B group. On the 90th d, the antibody titer response was observed to be 2627.58 mIU/mL in the BEVAC group and 2272.72 mIU/mL in the ENGERIX-B group. Two subjects in each group experienced pains at injection site after the first vaccination. A total of six subjects in both groups experienced a solicited adverse reaction, which included pains, swelling and redness at the injection site, three subjects in the group-B had a pain at the injection site after the third dose. No other serious adverse events occurred and no dose-related local or general symptoms were observed during the study.CONCLUSION: The vaccine is safe, efficacious and immunogenic in comparison with the well documented ENGERIX-B. | A Chowdhury A Santra CM Habibullah AA Khan J Karunakaramaiah TSA Kishore AVR Raju S Lahiri | 2005 | World Journal of Gastroenterology2005，11，7： | 12 |
| 2 | Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis显示文摘Systemic corticosteroids represent the standard treatment for autoimmune pancreatitis with IgG4-associated cholangitis.For steroid-dependent disease,azathioprine has been used for maintenance of remission.Mycophenolate mofetil has been used for transplant immunosuppression and more recently for autoimmune hepatitis;however,there are no case reports to date on the use of mycophenolate mofetil in adult patients with autoimmune pancreatitis.A patient with IgG4-mediated autoimmune pancreatitis and IgG4-associated cholangitis refractory to steroids and intolerant of azathioprine was treated with mycophenolate mofetil,which inhibits de novo guanosine synthesis and blockade of both B and T lymphocyte production.Introduction of mycophenolate mofetil and uptitration to 1000 mg by mouth twice daily over a treatment period of 4 mo was associated with improvement in the patient's energy level and blood glucose control and was not associated with any adverse events.The patient was managed without a biliary stent.However,there was a return of symptoms,jaundice,increase in transaminases,and hyperbilirubinemia when the prednisone dose reached 11 mg per day.In the first report of mycophenolate mofetil use in an adult patient with IgG4-associated autoimmune pancreatitis and IgG4-associated cholangitis,the introduction of mycophenolate mofetil was safe and well-tolerated without adverse events,but it did not enable discontinuation of the steroids.Mycophenolate mofetil and other immunomodulatory therapies should continue to be studied for maintenance of remission in the large subset of patients with refractory or recurrent autoimmune pancreatitis. | Jamie B Sodikoff Steven A Keilin Sheila J Bharmal Melinda M Lewis Gottumukkala S Raju Field F Willingham | 2012 | World Journal of Gastroenterology2012，18，18： | 6 |
| 3 | 氧化铝负载的银纳米颗粒高选择性催化合成亚胺(英)显示文摘The oxidative dehydrogenation of alcohols to aldehydes catalyzed by Ag nanoparticles supported on Al_2O_3 was studied.The catalyst promoted the direct formation of imines by tandem oxidative dehydrogenation and condensation of alcohols and amines.The reactions were performed under mild conditions and afforded the imines in high yield(up to 99%) without any byproducts other than H_2O.The highest activity was obtained over 5 wt%Ag/Al_2O_3 in toluene with air as oxidant.The reactions were also performed under oxidant-free conditions where the reaction was driven to the product side by the production of H_2 in the gas phase.The use of an efficient and selective Ag catalyst for the oxidative dehydrogenation of alcohol in the presence of amines gives a new green reaction protocol for imine synthesis. | Jerrik Mielby Raju Poreddy Christian Engelbrekt SΦren Kegns | 2014 | 催化学报2014，35，5： | 2 |
| 4 | 碱炉高效运行与维护实践显示文摘随着当前能源需求量的急速增长以及对环保要求的不断增强,造纸厂已经将安全和环保问题纳入到方针和行动的各个方面,如造纸厂着力于探索一些能够增强碱炉安全、环保、高效、高开机率的全局性改善措施。探索实践的内容如:熔融物抽取系统、自动清理风口系统、利用安全检修平台进行检修、有味气体的处理和焚烧、先进的工艺控制、先进的安全联锁等都在本文中有相关介绍。 | 于英民 Chandrasekaran R Arun A Mishra Anshul Raju R Ravishangar P S | 2013 | 中华纸业2013，34，14： | 2 |
| 5 | 显示文摘 | Parashar S Raju A R Rao C N R | 2003 | J Phys D: Appl Phys2003，36，17： | 1 |
| 6 | Endovenous treatment of patients with iliac-caval venous obstruction显示文摘 | Raju S | 2008 | J Cardiovasc Surg(Torino)2008，49，1： | 1 |
| 7 | Thermal, viscoelastic, solution and membrane properties of sodium alginate/hydroxyethylcellulose blends显示文摘 | Naidu B V K Sairam M Raju K V S N | 2005 | Carbohydrate Polymers2005，61，1： | 1 |
| 8 | Fast Isodata clustering algorithms 显示文摘 | Venkateswarlu N B Raju P S V S K | 1992 | Pattern Recognition1992，25，3： | 1 |
| 9 | Synthesis, characterization and effect of reaction parameters on swelling properties of acrylamide-sodium methacrylate superabsorbent copolymers 显示文摘 | Mohan Y M Murthy P S K Raju K M | 2005 | Reactive & Functional Polymers2005，63，： | 1 |
| 10 | Positioning of store brands显示文摘 | SAYMAN S HOCH S J RAJU J S | 2002 | Marketing Science2002，21，4： | 1 |
| 11 | Loss of correction in unstable comminuted dis- tal radius fractures with external fixation and bone grafting - a long term foUowup study显示文摘 | Raju P Kini S G | 2011 | J Orthop Surg Res2011，6，5： | 1 |
| 12 | Fairness and Channel Coordination显示文摘 | Cui T H Raju J S Zhang Z J | 2007 | Management Science2007，53，8： | 1 |
| 13 | Effect of butyric acid on performance, gastrointestinal tract health and carcass characteristics in broiler chickens 显示文摘 | Panda A K Rao S V R Raju M V L N | 2009 | Asian Aust J Anim Sci2009，22，7： | 1 |
| 14 | Structural engineering of polyurethane coatings for high performance applications 显示文摘 | Chattopadhyay D K Raju K V S N | 2007 | Progress in Polymer Science2007，32，： | 1 |
| 15 | Preparation and swelling behavior of macroporous poly (acrylamide-co-sodium methacrylate) superabsorbent hydrogels显示文摘 | Mohan Y M Murthy P S K Raju K M | 2006 | Journal of Applied Polymer Science2006，101，5： | 1 |
| 16 | The Impact of Environmental Uncertainty on the Market Orientation - Performance Relationship : A Study of the Hospital Industry显示文摘 | Subhash C Loniall P S Raju | 2001 | Journal of Economic and Social Research2001，3，1： | 1 |
| 17 | Analyses of surface cracks in finite plates under tension or bending loads显示文摘 | Newman Jr J C Raju I S | 1979 | NASA Technical Paper1979，1578，： | 1 |
| 18 | An empirical stress intensity factor equation for the surface crack显示文摘 | NEWMAN J J RAJU I S | 1981 | Engng Fracture Mech1981，15，： | 1 |
| 19 | A comparison between descending phlebography and duplex dopple investigation in the evaluation of reflux in chronic venous insufficiency:a challenge to phlebography as the 'gold standard'显示文摘 | Neglen P Raju S | 1992 | J Vasc Surg1992，16，5： | 1 |
| 20 | An empirical stress intensity factor equation for the surface crack显示文摘 | Newman J C Jr Raju I S | 1981 | Engng Fracture Mech1981，，15： | 1 |
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