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| 1 | Acute fatty liver of pregnancy associated with severe acute pancreatitis:A case report显示文摘Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed. | Cássio Vieira de Oliveira Alecsro Moreira Julio P Baima Leticia de C Franzoni Talles B Lima Fabio da S Yamashiro Kunie Yabuki Rabelo Coelho Ligia Y Sassaki Carlos Antonio Caramori Ferno G Romeiro Giovanni F Silva | 2014 | World Journal of Hepatology2014，6，7： | 3 |
| 2 | Genetic ancestry analysis in non-alcoholic fatty liver disease patients from Brazil and Portugal显示文摘AIM:To study the association between genetic ancestry,non-alcoholic fatty liver disease(NAFLD) metabolic characteristics in two cohorts of patients,from Brazil and Portugal. METHODS:We included 131 subjects from Brazil [(n = 45 with simple steatosis(S. Steatosis) and n = 86 with nonalcoholic steatohepatitis(NASH)] and 90 patients from Portugal(n = 66,S. Steatosis; n = 24,NASH). All patients had biopsy-proven NAFLD. In histologic evaluation NAFLD activity score was used to assess histology and more than 5 points defined NASH in this study. Patients were divided into two groups according to histology diagnosis:simple steatosis or non-alcoholic statohepatitis. Genetic ancestry was assessed using real-time polymerase chain reaction. Seven ancestry informative markers(AT3-I/D,LPL,Sb19.3,APO,FYNull,PV92,and CKMM) with the greatest ethnicgeographical differential frequencies(≥ 48%) were used to define genetic ancestry. Data were analyzed using R PROJECTS software. Ancestry allele frequencies between groups were analyzed by GENEPOP onlineand the estimation of genetic ancestry contribution was evaluated by ADMIX-95 software. The 5% alpha-error was considered as significant(P < 0.05). RESULTS:In the Brazilian sample,NASH was significantly more frequent among the elderly patients with diabetes(NASH 56 ± 1.1 years old vs S. Steatosis 51 ± 1.5 years old,P = 3.7 x 10-9),dyslipidemia(NASH 63% vs S. Steatosis 37%,P = 0.009),higher fasting glucose levels(NASH 124 ± 5.2 vs S. Steatosis 106 ± 5.3,P = 0.001) and Homeostatic Model of Assessment index > 2.5 [NASH 5.3(70.8%) vs S. Steatosis 4.6(29.2%) P = 0.04]. In the Portuguese study population,dyslipidemia was present in all patients with NASH(P = 0.03) and hypertension was present in a larger percentage of subjects in the S. Steatosis group(P = 0.003,respectively). The genetic ancestry contribution among Brazilian and Portuguese individuals with NASH was similar to those with S. Steatosis from each cohort(Brazilian cohort:P = 0.75; Portuguese cohort:P = 0.97). Nonetheless,the genetic ancestry contribution of the Brazilian and Portuguese population were different,and a greater European and Amerindian ancestry contribution was detected in the Portuguese population while a higher African genetic ancestry contribution was observed in Brazilian population of both NASH and S. Steatosis groups.CONCLUSION:There was no difference between the genetic ancestry contribution among Brazilian and Portuguese individuals with NASH and S. Steatosis from each cohort. | Lourianne Nascimento Cavalcante Jose Tadeu Stefano Mariana V Machado Daniel F Mazo Fabiola Rabelo Kiyoko Abe Sandes Flair Jose Carrilho Helena Cortez-Pinto Andre Castro Lyra Claudia P de Oliveira | 2015 | World Journal of Hepatology2015，7，10： | 2 |
| 3 | Detection of fungi in beans by the laser biospeckle technique显示文摘 | Braga R A Rabelo G F Granato L R | 2005 | Biosystems Engineering2005，91，4： | 1 |
| 4 | The Wnt signaling pathway and rheumatoid arthritis显示文摘 | Rabelo F D da Mota L M Lima R A | 2010 | Autoimmun Rev2010，9，4： | 1 |
| 5 | Pro- and anti-inflammatory cytokines in steatosis and steatohepatitis 显示文摘 | Rabelo F Oliveira CP Faintuch J Mazo DF Lima VM Stefano JT Barbeiro HV Soriano FG Alves VA Carrilho FJ | 2010 | Obes Surg2010，20，7： | 1 |
| 6 | Detection of Theileria and Babesia in brown brocket deer (Mazama gouazoubira) and marsh deer (Blastocerus dichotomus) in the State of Minas Gerais, Brazil显示文摘 | Da Silveira J A G Rabelo 1 M L Ribeiro M F B | 2011 | Vet Parasitol2011，177，1： | 1 |
| 7 | Detection of fungi in beans by the laser biospeckle technique显示文摘 | Braga Jr R A Rabelo G F Granato L R | 2005 | Biosystems Engineering2005，91，4： | 1 |
| 8 | Laser speckle techniques applied to study quality of fruits显示文摘 | Rabelo G F Braga Jr R A Fabbro I M D | 2005 | Revista Brasileira de Engenharia Agrícola e Ambiental2005，9，5： | 1 |
| 9 | Calculations of the thermal expansion, cohesive energy and thermodynamic stability of a Van der Waals crystal - fullerene C60 显示文摘 | ZUBOV V 1 TRET1AKOV N P TEIXE1RA RABELO J N SANCHEZ ORT1Z J F | 1995 | Phys Lett A1995，198，1： | 1 |
| 10 | Reduction of arterial pressure and double product at rest after resistance ex- ercise training in elderly hypertensive women 显示文摘 | TERRA D F MOTA M R RABELO H T | 2008 | Arquivos Brasileiros de Cardiologia2008，91，： | 1 |
| 11 | Calculations of the thermal expansion, cohesive energy and thermodynamic stability of a van der Waals crystal-fullerene C60显示文摘 | ZUBOV V I TRETIAKOV N P TEIXEIRA RABELO J N SANCHEZ ORTIZ J F | 1995 | Phys Lett A1995，198，56： | 1 |
| 12 | Propofol-induced sleep: Polysomnographic evaluation of patients with obstructive sleep apnea and controls显示文摘 | Fábio A.W. Rabelo Adriano Braga Daniel S. Küpper José A.A. De Oliveira Fernando M. Lopes Pedro Luiz Vaz de Lima Mattos Shirley G. Barreto Heidi H. Sander Regina M.F. Fernandes Fabiana C.P. Valera | 2010 | Otolaryngology - Head and Neck Surgery2010，，2： | 1 |
| 13 | Frequency response of biospeckle laser images of bean seeds contaminated by fungi显示文摘 | Rabelo G F Enes A M Junior R A B | 2011 | Biosystems Engineering2011，110，3： | 1 |
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