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1篇 您的检索式:作者名="R.K.Khajuria"
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1Development of a validated UPLC-qTOF-MS/MS method for determination of bioactive constituent from Glycyrrhiza glabra显示文摘An ultra-performance liquid chromatography quadrupole time of flight mass spectrometry(UPLC-qTOF-MS/MS) method was developed and validated for the simultaneous determination of glycyrrhizin and glycyrrhetic acid.These analytes were separated on a reverse phase C18 column using a mobile phase of acetonitrile:2% acetic acid in water(75:25,v/v) with a flow rate of 200 mL/min.The qTOF-MS was operated under multiple reaction monitoring(MRM) mode using the electrospray ionization(ESI) technique with positive ion polarity.A comparison of three different extraction techniques i.e.accelerated solvent extraction(ASE),extraction under ultrasonic waves(USW) and the classical extraction by percolation(CE) method was done and quantification of these extracts was also carried out by the proposed method.D.K.Gupta M.K.Verma R.Anand R.K.Khajuria 2013Journal of Pharmaceutical Analysis2013,3,3:0
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