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| 1 | Ferroptosis is an autophagic cell death process显示文摘Ferroptosis 是调整坏死的一种铁依赖者形式。它在各种各样的人的疾病被含有,包括 ischemic 机关损坏和癌症。这里,我们报导 autophagy 的关键角色,特别地细胞的铁存储蛋白质(作为 ferritinophagy 知道的一个过程) 的 autophagic 降级,在 ferroptosis。用 RNAi,屏蔽结合了随后的基因分析,我们作为 ferroptosis 的积极管理者识别了多重 autophagy 相关的基因。Ferroptosis 正式就职导致了 autophagy 激活和 ferritin 和 ferritinophagy 货物受体 NCOA4 的作为结果的降级。一致地,由 autophagy 的阻塞的 ferritinophagy 的抑制或废除的 NCOA4 击倒联系 ferroptosis 的细胞的易变的铁的累积和反应的氧种类,以及最终的 ferroptotic 细胞死亡。因此, ferroptosis 是一个 autophagic 房间死亡过程,并且调停 NCOA4 的 ferritinophagy 由控制细胞的铁动态平衡支持 ferroptosis。 | Minghui Gao Prashant Monian Qiuhui Pan Wei Zhang Jenny Xiang Xuejun Jiang | 2016 | Cell Research2016，26，9： | 138 |
| 2 | Embedding Countably Generated Algebras into Simple 2-Generated Algebras显示文摘 | Qiuhui Mo Xiangui Zhao Qingnian Pan | 2017 | Algebra Colloquium2017，24，3： | 3 |
| 3 | Effect of fertilization on selenium content of tea and the nutritional function of Se- enriched tea in rats显示文摘 | Qiuhui Hu Genxing Pan Jianchnn Zhu | 2002 | Plant and Soil2002，238，： | 1 |
| 4 | Let-7 regulates self renewal and tumorigenicity of breast cancer cells 显示文摘 | Fengyan Yu Herui Yao Pengcheng Zhu Xiaoqin Zhang Qiuhui Pan Chang Gong Yijun Huang Xiaoqu Hu Fengxi Su Judy Lieberman and Erwei Song | 2007 | Cell 20072007，，： | 1 |
| 5 | MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells显示文摘 | Gang Li Zhengrong Wu Ying Peng Xiong Liu Juan Lu Lu Wang Qiuhui Pan Min-Liang He Xiang-Ping Li | 2010 | Cancer Letters2010，，1： | 1 |
| 6 | Mutual inhibition between YAP and SRSF1 maintains long non-coding RNA, Malat1-induced tumourigenesis in liver cancer显示文摘 | Jiayi Wang Hongmei Wang Yue Zhang Ni Zhen Li Zhang Yongxia Qiao Wenhao Weng Xiangfan Liu Lifang Ma Weifan Xiao Wenjun Yu Qinghua Chu Qiuhui Pan Fenyong Sun | 2014 | Cellular Signalling2014，，： | 1 |
| 7 | Uptake and transport of selenite and selenate by soybean seeding of two genotypes 显示文摘 | Zhang Yanling Pan Genxing Chen Jin Hu Qiuhui | 2003 | Plant and Soil2003，253，： | 1 |
| 8 | Effect of fertili- zation on selenium content of tea and the nutritional function of Se-enriched tea in rats 显示文摘 | Hu Qiuhui Pan Genxing Zhu Jianchun | 2002 | Plant and Soil2002，238，： | 1 |
| 9 | Characterization of function and regulation of miR-24-1 and miR-31显示文摘 | Fenyong Sun Jiayi Wang Qiuhui Pan Yongchun Yu Yue Zhang Yang Wan Ju Wang Xiaoyan Li An Hong | 2009 | Biochemical and Biophysical Research Communications2009，，3： | 1 |
| 10 | let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells显示文摘 | Fengyan Yu Herui Yao Pengcheng Zhu Xiaoqin Zhang Qiuhui Pan Chang Gong Yijun Huang Xiaoqu Hu Fengxi Su Judy Lieberman Erwei Song | 2007 | Cell2007，，6： | 1 |
| 11 | let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells显示文摘 | Fengyan Yu Herui Yao Pengcheng Zhu Xiaoqin Zhang Qiuhui Pan Chang Gong Yijun Huang Xiaoqu Hu Fengxi Su Judy Lieberman Erwei Song | 2007 | Cell2007，，6： | 1 |
| 12 | Common Ancestor and Genetic Diversity in Penna Model显示文摘The characteristic of individual is described by the Penna model. Based oninformation entropy and the Penna model we define the entropy in the Penna modelto discuss common ancestors and genetic diversity for two reproduction modes withand without mutation. About the problem of common ancestor, we find that all livingindividuals at any time step have a set of common ancestors which belongs to differenttimes. They have the most recent common ancestor and earlier common ancestors.The analysis of genetic diversity shows that the complexity of ecosystems is caused bymutations and there is no contribution of sexual reproduction to conserving geneticdiversity at long time scales. Moreover, in stable environment genetic diversity inasexual reproduction mode is higher than that in the sexual case. | Qiuhui Pan Zhirui Wang Zhen Wang Mingfeng He | 2010 | Communications in Computational Physics2010，7，1： | 0 |
| 13 | Global profiling of O-GlcNAcylated and/or phosphorylated proteins in hepatoblastoma显示文摘O-linked-β-N-acetylglucosamine(O-GlcNAc)glycosylation(O-GlcNAcylation)and phosphorylation are critical posttranslational modifications that are involved in regulating the functions of proteins involved in tumorigenesis and the development of various solid tumors.However,a detailed characterization of the patterns of these modifications at the peptide or protein level in hepatoblastoma(HB),a highly malignant primary hepatic tumor with an extremely low incidence in children,has not been performed.Here,we examined O-GlcNAc-modified or phospho-modified peptides and proteins in HB through quantitative proteomic analysis of HB tissues and paired normal liver tissues.Our results identified 114 O-GlcNAcylated peptides belonging to 78 proteins and 3494 phosphorylated peptides in 2088 proteins.Interestingly,41 proteins were modified by both O-GlcNAcylation and phosphorylation.These proteins are involved in multiple molecular and cellular processes,including chromatin remodeling,transcription,translation,transportation,and organelle organization.In addition,we verified the accuracy of the proteomics results and found a competitive inhibitory effect between O-GlcNAcylation and phosphorylation of HSPB1.Further,O-GlcNAcylation modification of HSPB1 promoted proliferation and enhanced the chemotherapeutic resistance of HB cell lines in vitro.Collectively,our research suggests that O-GlcNAc-modified and/or phospho-modified proteins may play a crucial role in the pathogenesis of HB. | Hang Song Ji Ma Zhixuan Bian Shuhua Chen Jiabei Zhu Jing Wang Nan Huang Minzhi Yin Fenyong Sun Min Xu Qiuhui Pan | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 0 |
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