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6篇 您的检索式:作者名="Qiufeng Zeng"
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1Serum trimethylamine-N-oxide and gut microbiome alterations are associated with cholesterol deposition in the liver of laying hens fed with rapeseed meal显示文摘Sinapine derived from cruciferous plants could be converted into trimethylamine by intestinal microbiota.Its metabolite,trimethylamine N-oxide(TMAO),is closely linked to increased risk of cardiovascular disease and fat deposition in mammals.Hens fed with rapeseed meal(RSM)suffered from fatty liver hemorrhage syndrome(FLHS).This study was conducted to investigate whether RSM-induced fatty liver is due to TMAO via altering microbiota composition and diversity.At 33 weeks of age,600 laying hens were randomly divided into 5 treatment groups,namely control and 14%RSM treatment groups(DY5,with 16.2% erucic acid [EA]and 74.66% glucosinolate[Gl]contents;MB1,with 3.50% EA and 43.23 %Gl contents;DY6,with 6.7% EA and 22.67% Gl contents;XH3,with 44.60% EA and 132.83% Gl contents)for 8 weeks.Results revealed that 3 hens died due to liver hemorrhage after ingesting 14% RSM diet.The 14% RSM decreased serum low-density lipoprotein cholesterol(LDL-C)content(P<0.01)while tended to increase serum TMAO content compared to the control group(P=0.08).The 14% RSM diet increased red oil O optical density(P<0.01),and increased total cholesterol(TC)and LDL-C content in the liver(P<0.01,and P<0.01,respectively).The 14%RSM decreased liver total bile acid(TBA)content compared to the control(P<0.01).The DY6 had a higher TBA content in the liver than the XH3(P<0.01).The 14%RSM decreased mRNA abundance of liver X receptors alpha(LXR-α,P=0.01),and increased mRNA abundance of sterol response element binding protein 2(SREBP-2,P=0.04).Results revealed that the in-feed RSM could alter richness and diversity of cecal microbiota compared to the control(P<0.05).Liver TC content and serum TMAO showed a negative relationship with Proteobacteria and Actinobacteria(P=0.04).In conclusion,14%RSM increased liver TC and induced high liver score of FLHS,which was possibly associated with the altered cecal microbiota composition,increased serum TMAO levels and LXR-αand SREBP-2 expressions.Liping Zhu Jianping Wang Xuemei Ding Shiping Bai Qiufeng Zeng Yue Xuan Gregory S.Fraley Keying Zhang 2021Animal Nutrition2021,,4:2
2Effects of dietary nanocrystalline cellulose supplementation on growth performance,carcass traits,intestinal development and lipid metabolism of meat ducks显示文摘The influence of nanocrystalline cellulose(NCC) supplementation on growth performance, carcass traits,intestinal development, and lipid metabolism was assessed in 600 one-day-old male meat ducks(Cherry Valley ducks) from 1 to 35 d of age. Diets were supplemented with 0,200,500,800 and 1,500 mg/kg NCC during both the starter(1-14 d) and grower(15-35 d) phases. Each dietary treatment consisted of 8 replicate cages of 15 birds. Supplementation of NCC was associated with dose dependent increases in BW gain and feed intake(P < 0.01) during 1-14 d of age and in BW at 35 d of age. As NCC content increased,the percentage of breast meat weight(P < 0.05) and leg(with bone) weight(P < 0.05) linearly increased,while the percentage of abdominal fat weight(P < 0.01) linearly decre.ased in ducks at 35 d of age.Supplementation of NCC resulted in a dose-dependent increase in the weight(P < 0.05) and density(P < 0.01) of the cecum. The percentage of total hepatic lipid content(P < 0.01) at 14 d of age and serum triglyceride(TG) concentration(P = 0.052) at 35 d of age linearly decreased with increasing of dietary NCC addition. In conclusion, inclusion of 1,500 mg/kg NCC in feed resulted in the greatest improvements in duck performance, intestinal development and lipid deposition.Haoyue Han Keying Zhang Xuemei Ding Shiping Bai Yueheng Luo Jianping Wang Huanwei Peng Qiufeng Zeng 2016Animal Nutrition2016,,3:2
3Effects of a multi-enzyme complex on growth performance,nutrient utilization and bone mineralization of meat duck显示文摘Background:Previous studies with broiler have shown dietary supplementation with multi-enzyme complex containing non-starch polysaccharides(NSP) degrading enzymes and phytase is efficient in releasing phosphorus(P),calcium(Ca),energy and amino acids from corn-soybean meal diets or corn-sorghum diets,hence compensating considerable levels of nutrients in formulation.Notwithstanding,such potentials have not been well defined in duck nutrition.Giving China being the largest duck producing country,we conducted this study to establish adequate specifications of major nutrients along with multi-enzyme complex to meat duck from day-old to slaughter,focusing on performance,utilization of nutrients and bone mineralization.Five dietary treatments were:Positive control(PC,T1):the nutrients concentration of diet for 1 to 14 d of age were apparent metabolizable energy(AME) 2,800 kcal/kg,crude protein(CP)19.39%,Ca 0.85%,available phosphorus(avP) 0.42%;for 15 to 35 d of age these parameters were AME2,900 kcal/kg,CP 16.47%,Ca 0.76%,avP 0.38%;Negative control 1(NC1,T2),the AME and digestible amino acids(DAA)were reduced by 70 kcal/kg and 2.0%,avP and Ca by 1.0 g/kg from PC diet;Negative control 2(NC2T4),the downspec from PC diet was AME 100 kcal/kg,DAA 2.5%,avP 1.5 g/kg and Ca 1.2 g/kg;The enzyme complex was added at the same dosage(200 ml7 1,000 kg) on NCI(T3) and NC2(T5) diets.Results:Comparing with the ducks fed on T1,T3 and T5 diets,the birds fed on NC2 diet showed the lowest(P < 0.05)body weight(d 14 and 35),feed intake(d 35),tibia ash,Ca and P contents(d 14 and 35),and the utilization of nutrients(P< 0.05).The supplementation with the enzyme complex to the NC diets restored growth rate,utilization of nutrients and bone mineralization to the level of the PC diet,and increased AME by 60 kcal/kg and117 kcal/kg,respectively for the NCI and NC2 diets.Conclusion:These results suggest that down-spec AME by 100 kcal/kg,DAA by 2.5%,avP by 1.5 g/kg and Ca by1.2 g/kg caused detrimental effects on duck performance compared with those fed on the PC diet,and these performance losses can be compensated by the addition of the multiple-enzyme complex.Qiufeng Zeng Xueqin Huang Yuheng Luo Xuemei Ding Shiping Bai Jianping Wang Yue Xuan Zhuowei Su Yonggang Liu Keying Zhang 2015Journal of Animal Science and Biotechnology2015,6,4:1
4Effect of dietary canthaxanthin and 25-hydroxycholecalciferol supplementation on the performance of duck breeders under two different vitamin regimens显示文摘Background: Dietary canthaxanthin(CX), 25-hydroxycholecalciferol(25-OH-D3) and vitamins have been widely reported to be involved in productive and reproductive performance of broiler breeders. However, limited information is available for duck breeders. In this study, a total of 1,560 Cherry Valley SM3 duck breeder females and 312 males were used to assess if the addition of CX and 25-OH-D3 could increase the performance of duck breeders under two different dietary vitamin regimens. Four diets were used under a 2 × 2 factorial arrangement with 2 kinds of vitamin premixes(REGULAR and HIGH; HIGH premix had higher levels of all vitamins except K3 than REGULAR premix), and with or without the supplementation of the mixture of CX(6 mg/kg) and 25-OH-D3(0.069 mg/kg). The ducks were fed ad libitum with pelleted diets based on corn-soybean meal from 38 to 77 wk of age.Results: HIGH vitamin premix decreased malondialdehyde(MDA) level(P < 0.001) of egg yolk, increased hatchability of fertile eggs(P = 0.029), increased hatchability of total eggs(P = 0.029), and decreased serum protein carbonyl level(P = 0.037) of breeder males. The mixture of CX and 25-OH-D3 increased serum calcium of breeder females(P = 0.010), decreased the cracked egg rate(P = 0.001), increased the pigmentation of egg yolk(P < 0.001)and male bill(P < 0.001), and decreased MDA level of egg yolk(P < 0.001) and male serum(P = 0.034). Interactive effects were observed in cracked egg rate(P = 0.038), shell thickness(P = 0.011) and serum phosphorus(P = 0.026)of breeder females. HIGH vitamin premix together with the mixture of CX and 25-OH-D3 decreased cracked egg rate and increased shell thickness of duck breeders. Serum phosphorus was decreased in duck breeder females fed REGULAR vitamin premix without the addition of the CX and 25-OH-D3 mixture.Conclusions: Dietary HIGH vitamin premix increased antioxidant status of eggs and breeder males, and increased hatchability. The mixture of CX and 25-OH-D3 enhanced egg shell quality, and promoted pigmentation and antioxidant status of eggs and breeder males.Zhouzheng Ren Shizhen Jiang Qiufeng Zeng Xuemei Ding Shiping Bai Jianping Wang Yuheng Luo Zhuowei Su Yue Xuan Bing Yao Fernando Cisneros Keying Zhang 2016Journal of Animal Science and Biotechnology2016,7,2:0
5Distribution of Heavy Metals in Common Energy Feedstuffs and Protein Feedstuffs in Sichuan Province显示文摘[Objectives] The paper was designed to investigate the heavy metal distribution in energy feedstuffs and protein feedstuffs commonly used in Sichuan Province,in order to provide scientific basis for safe production of feedstuffs and animal products. [Methods] The contents of manganese( Mn),copper( Cu),zinc( Zn),vanadium( V),chromium( Cr),cobalt( Co),nickel( Ni),selenium( Se),molybdenum( Mo),cadmium( Cd),arsenic( As),mercury( Hg)and lead( Pb) in 68 samples of energy feedstuffs [corn,wheat,distillers dried grains with solubles( DDGS),corn bran with syrup,wheat bran and rice bran]and 61 samples of protein feedstuffs( corn gluten meal,corn germ meal,soybean meal,rapeseed meal and cottonseed meal) collected from Sichuan province were determined by inductively coupled plasma mass spectrometry( ICP-MS). [Results]( 1) The over standard rates of Cu,Cr and Pb in corn were 5. 00%,20. 00% and 5. 00%,respectively; and the means of over standard samples were 11. 00,1. 41 and 1. 06 mg/kg,respectively. The over standard rates of Cu,Zn,Cr,Se and Pb in wheat were 50. 00%,30. 00%,50. 00%,20. 00% and 30. 00%,respectively; and the means of over standard samples were 12. 96,54. 67,4. 92,0. 53 and 0. 72 mg/kg,respectively.( 2) The over standard rates of Cu,Zn,Cr,Se,Cd and Pb in wheat bran were 100. 00%,54. 55%,81. 82%,9. 09%,45. 45% and 72. 73%,respectively; and the means of over standard samples was 16. 01,62. 00,13. 96,0. 82,0. 42 and 1. 99 mg/kg,respectively. The over standard rates of Cu,Zn,Cr,As,Se,Cd and Pb in rice bran were 83. 33%,16. 67%,83. 33%,83. 33%,16. 67%,66. 67% and 100. 00%,respectively; and the means of over standard samples were 11. 48,64. 00,5. 37,1. 05,0. 32,0. 23 and 19. 57 mg/kg,respectively.( 3) The over standard rates of Cu,Zn,Cr,As,Se and Pb in corn germ meal were 25. 00%,37. 50%,75. 00%,12. 50%,25. 00% and 50. 00%,respectively; and the means of over standard samples were 13. 50,64. 00,6. 10,1. 82,0. 46 and 1. 66 mg/kg,respectively. The over standard rates of Cu,Cr and Se in corn gluten meal were 11. 11%,55. 56% and 55. 56%,respectively; and the means of over standard samples were 11. 40,1. 56 and 0. 94 mg/kg,respectively. The over standard rates of Zn,Cr and Pb in corn bran with syrup were 44. 44%,77. 78% and 55. 56%,respectively; and the means of over standard samples were 57. 50,6. 13 and 1. 65 mg/kg,respectively. The over standard rates of Cu,Zn,Cr,Se,Cd and Pb in DDGS were 33. 33%,58. 33%,66. 67%,8. 33%,8. 33% and 66. 67%,respectively; and the means of over standard sample were 11. 75,62. 57,5. 57,0. 30,0. 62 and 4. 47 mg/kg,respectively.( 4) The over standard rates of Cr and Se in soybean meal was 15. 00% and25. 00%,respectively; and the means of over standard sample were 3. 90 and 1. 63 mg/kg,respectively. The over standard rates of Cr,Se and Pb in cottonseed meal were 40. 00%,30. 00% and 15. 00%,respectively; and the means of over standard samples were 3. 43,1. 18 and 3. 14 mg/kg,respectively. The over standard rates of Cr,As,Se,Cd and Pb in rapeseed meal were 81. 82%,18. 18%,45. 45%,9. 09% and 72. 73%,respectively; and the means of over standard samples were 7. 48,2. 22,0. 36,0. 24 and 4. 91 mg/kg,respectively. [Conclusions]The heavy metal pollution is more serious in grain by-products and cottonseed meal; the contents of Cr and Pb in feed ingredient are seriously excessive,which is potentially dangerous,and should be paid great attention.Bai Xue Yuan Zehong Wang Jianping Ding Xuemei Bai Shiping Zeng Qiufeng Zhang Keying 2017Animal Husbandry and Feed Science2017,9,3:0
6Dietary resistant starch ameliorating lipopolysaccharide-induced inflammation in meat ducks associated with the alteration in gut microbiome and glucagon-like peptide 1 signaling显示文摘Background:Consumption of resistant starch(RS)has been associated with various intestinal and systemic health benefits,but knowledge of its effects on intestinal health and inflammatory response in stressed birds is limited.Here,we examined how dietary RS supplementation from 12%raw potato starch(RPS)modulated inflammatory severity induced by lipopolysaccharide(LPS)in meat ducks.Results:LPS administration at 14,16,and 18 d(chronic challenge)decreased body weight(BW)and glucagon-like peptide 1 receptor(GLP-1R)level with higher intestinal permeability and inflammation,evident by higher proinflammatory cytokine levels.Dietary 12%RPS supplementation enhanced Claudin-1 and GLP-1R expression,along with lower levels of inflammatory factors in both ileum and serum.Microbiome analysis showed that RS treatment shifted microbial structure reflected by enriched the proportion of Firmicutes,Bifidobacterium,Ruminococcus,etc.Dietary RS addition also significantly increased the concentrations of propionate and butyrate during chronic LPS challenge.Furthermore,response to acute challenge,the ducks received 2 mg/kg BW LPS at 14 d had higher concentrations of serum endotoxins and inflammatory cytokines,as well as upregulated transcription of toll like receptor 4(TLR4)in ileum when compared to control birds.Analogous to GLP-1 agonist liraglutide,dietary RS addition decreased endotoxins and inflammation cytokines,whereas it upregulated the GLP-1 synthesis related genes expression.Meanwhile,dietary RS supplementation suppressed the acute LPS challenge-induced TLR4 transcription.Conclusions:These data suggest that dietary 12%RPS supplementation could attenuate the LPS-induced inflammation as well as intestinal injury of meat ducks,which might involve in the alteration in gut microbiota,SCFAs production and the signaling pathways of TLR4 and GLP-1/GLP-1R.Simeng Qin Weiqiang Bai Todd JApplegate Keying Zhang Gang Tian Xuemei Ding Shiping Bai Jianping Wang Li Lv Huanwei Peng Yue Xuan Qiufeng Zeng 2022Journal of Animal Science and Biotechnology2022,13,6:0
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