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| 1 | Numerical simulation of hydraulic fracturing and associated microseismicity using finite-discrete element method显示文摘Hydraulic fracturing(HF) technique has been extensively used for the exploitation of unconventional oil and gas reservoirs. HF enhances the connectivity of less permeable oil and gas-bearing rock formations by fluid injection, which creates an interconnected fracture network and increases the hydrocarbon production. Meanwhile, microseismic(MS) monitoring is one of the most effective approaches to evaluate such stimulation process. In this paper, the combined finite-discrete element method(FDEM) is adopted to numerically simulate HF and associated MS. Several post-processing tools, including frequency-magnitude distribution(b-value), fractal dimension(D-value), and seismic events clustering,are utilized to interpret numerical results. A non-parametric clustering algorithm designed specifically for FDEM is used to reduce the mesh dependency and extract more realistic seismic information.Simulation results indicated that at the local scale, the HF process tends to propagate following the rock mass discontinuities; while at the reservoir scale, it tends to develop in the direction parallel to the maximum in-situ stress. | Qi Zhao Andrea Lisjak Omid Mahabadi Qinya Liu Giovanni Grasselli | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014，6，6： | 8 |
| 2 | Spectral-Element andAdjointMethods in Seismology显示文摘We provide an introduction to the use of the spectral-elementmethod (SEM)in seismology. Following a brief review of the basic equations that govern seismicwave propagation, we discuss in some detail how these equations may be solved numericallybased upon the SEM to address the forward problem in seismology. Examplesof synthetic seismograms calculated based upon the SEM are compared to datarecorded by the Global Seismographic Network. Finally, we discuss the challenge ofusing the remaining differences between the data and the synthetic seismograms toconstrain better Earth models and source descriptions. This leads naturally to adjointmethods, which provide a practical approach to this formidable computational challengeand enables seismologists to tackle the inverse problem. | Jeroen Tromp Dimitri Komatitsch Qinya Liu | 2008 | Communications in Computational Physics2008，3，1： | 5 |
| 3 | Spectral-element simulations of elastic wave propagation in exploration and geotechnical applications显示文摘We apply the spectral-element method(SEM),a high-order finite-element method(FEM) to simulate seismic wave propagation in complex media for exploration and geotechnical problems. The SEM accurately treats geometrical complexities through its flexible FEM mesh and accurately interpolates wavefields through high-order Lagrange polynomials. It has been a numerical solver used extensively in earthquake seismology. We demonstrate the applicability of SEM for selected 2D exploration and geotechnical velocity models with an open-source SEM software package SPECFEM2D. The first scenario involves a marine survey for a salt dome with the presence of major internal discontinuities,and the second example simulates seismic wave propagation for an open-pit mine with complex surface topography. Wavefield snapshots,synthetic seismograms,and peak particle velocity maps are presented to illustrate the promising use of SEM for industrial problems. | Lin Zheng Qi Zhao Bernd Milkereit Giovanni Grasselli Qinya Liu | 2014 | Earthquake Science2014，27，2： | 4 |
| 4 | Octreotide protects against hepatic ischemia/ reperfusion injury via HO-l-mediated autophagy显示文摘 | Shuangfa Zou Huiping Sun Keith A. Candiotti Yanhua Peng Qinya Zhang Weiqiang Xiao Shuwu Zhao Liqiang Wu Jinfeng Yang | 2018 | Acta Biochimica et Biophysica Sinica2018，50，3： | 3 |
| 5 | 南加州地壳的伴随层析成像显示文摘使用基于伴随方法的反演策略,研制出了南加州地壳的三维地震模型。该模型涉及到16次层析成像迭代,需要6800次波场模拟和总计80万个中心处理单位小时。与南加州地震中心给出的最初三维模型比较,该新的地壳模型揭示了更强的非均匀性,包括±30%的局部变化。模型说明了诸如沉积盆地和横跨断层的构造反差的浅部特征。也揭示了深部的地壳特征,从而帮助重建诸如俯冲捕获洋壳碎块的南加州构造。新模型有助于对地震危险性做出更实际而准确的评估。 | Carl Tape Qinya Liu Alessia Maggi Jeroen Tromp 徐文杰(译) 吕春来(校) | 2009 | 世界地震译丛2009，40，5： | 2 |
| 6 | Target Extension-Activated DNA Walker on Nanoparticles for Digital Counting-Based Analysis of MicroRNA显示文摘MicroRNAs(miRNAs),especially exosomal miRNAs,are promising noninvasive biomarkers in early-stage cancer diagnosis and disease treatment monitoring.However,their precise and sensitive quantification remains challenging due to their small size and low abundance.Herein,we have developed a nanoparticle-confined DNA walker strategy for the specific detection of miRNA.In the existence of the target miRNA;the on-particle DNA walking reaction will be initiated,providing a fluorescence-positive nanoparticle.Otherwise,the nanoparticle would be fluorescence-negative.Utilizing the total internal reflection fluorescent microscope(TIRFM)to digitally count the fluorescence-positive nanoparticles,the proposed method possesses a detection limit of 0.2 pmol/L miRNA and can accurately distinguish the single-base mismatched target.This design combines the merits of the DNA walker for signal amplification and the TIRFM for highly sensitive detection,paving a new way for the digital counting-based analysis of exosomal miRNAs. | Qinya Feng Yuqing Zhai Wei Ren Chenghui Liu | 2021 | Chinese Journal of Chemistry2021，39，6： | 1 |
| 7 | Fabrication of Highly Porous Chromium Carbide with Multiple Pore Structure显示文摘 | Ziqiang Dong Qinya Zhang Weixing Chen | 2014 | J. Am. Ceram. Soc2014，，： | 1 |
| 8 | 全球整形美丽盛宴显示文摘在科技新时代,想要改头换面或是雕琢体型真是一点也不难,整形美容技术就能让原本有限的美丽得到大跨步的跃进,不论是脸形还是身材。因而,如今的整形科技俨然成为了最简单的供需问题,你可知道不同国家的女性都热衷于把身体的哪个部位"塑造"得更美丽?又有哪些地区的哪类整形术最优异呢? | Qinya | 2008 | 中国科学美容2008，，8： | 0 |
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