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| 1 | An Exploratory Analysis of Vegetation Strategies to Reduce Shallow Landslide Activity on Loess Hillslopes, Northeast Qinghai-Tibet Plateau, China显示文摘Heavy summer rainfall induces significant soil erosion and shallow landslide activity on the loess hillslopes of the Xining Basin at the northeast margin of the Qinghai-Tibet Plateau. This study examines the mechanical effects of five native shrubs that can be used to reduce shallow landslide activity. We measured single root tensile resistance and shear resistance, root anatomical structure and direct shear and triaxial shear for soil without roots and five root- soil composite systems. Results show that Atriplex canescens (Pursh) Nutt. possessed the strongest roots, followed by Caragana korshinskii Kom., Zygophyllum xanthoxylon (Bunge) Maxim., Nitraria tangutorum Bobr. and Lycium chinense Mill. Single root strength and shear resistance relationships with root diameter are characterized by power or exponential relations, consistent with the Mohr- Coulomb law. Root mechanical strength reflects their anatomical structure, especially the percentage of phloem and xylem cells, and the degree and speed of periderm lignifications. The cohesion force of root- soil composite systems is notably higher than that of soil without roots, with increasing amplitudes of cohesion force for A. canescens, C. korshinskii, Z. xanthoxylon, N. tangutorum and L. chinense of 75.9%, 75.1%, 36.2%, 24.6% and 17.0 % respectively. When subjected to shear forces, the soil without root samples show much greater lateral deformation thanthe root-soil composite systems, reflecting the restraining effects of roots. Findings from this paper indicate that efforts to reduce shallow landslides in this region by enhancing root reinforcement will be achieved most effectively using A. canescens and C. korshinskii. | HU Xia-song BRIERLEY Gary ZHU Hai-li LI Guo-rong FU Jiang-tao MAO Xiao-qing YU Qin-qin QIAO Na | 2013 | Journal of Mountain Science2013，10，4： | 41 |
| 2 | P53-mediated cell cycle arrest and apoptosis through a caspase-3-independent,but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells显示文摘瞄准:在 vitro 在导致 oridonin 的 MCF-7human 乳癌房间 apoptosis 学习 caspase-3-independent 机制。方法:oridonintreated MCF-7 房间的生存能力被 MTT (thiazole 蓝色) 测量试金。有压缩原子核的 Apoptotic 房间被阶段对比显微镜学设想。Nucleosomal DNA 破碎是由统帅玫瑰胶化电气泳动的 assayed。apoptotic 比率被决定由喂奶脱氢酶试金。房间周期引申 andmitochondrial 膜潜力被流动 cytometric 分析测量。Bax, Bcl-2, caspase-3, caspase-9,热吃惊蛋白质(Hsp ) 90, p53, p-p53, p21,(自动数据处理核糖) Poly,聚合酶(PARP ) ,和激活 caspase 的 DNase (ICAD ) 蛋白质表情的禁止者被西方的污点分析检测。结果:Oridonin 在一个时间依赖者和剂量依赖者举止禁止了房间生长。房间周期被改变通过起来 p53 和 p21 蛋白质表情的规定。Pancaspase inhibitorZ-VAD-fmk 和 calpain 禁止者 II 两个都减少了房间死亡比率。Nucleosomal DNA 破碎并且下面 DeltaPhimit 的规定在导致 oridonin 的 MCF-7 房间 apoptosis 被检测,它涉及一条 postmitochondrial caspase-9-dependent 小径。减少的 Bcl-2 和 Hsp90expression 层次和 p21 表示层次断然与 phosphorylated p53 phosphorylation 的提高的层次被相关。而且, PARP 部分被劈开 bycalpain 而非由 capase-3。结论:DNA 损坏在线粒体陆地 caspase-9 小径以及调停 p53 的房间周期拘捕挑起了引申,但是不与在导致 oridonin 的 MCF-7 房间的 caspase-3activity 有关。 | Qiao CUI Jing-hua YU Jin-nan WU Shin-ichi TASHIRO Satoshi ONODERA Mutsuhiko MINAMI Takashi IKFJIMA | 2007 | Acta Pharmacologica Sinica2007，28，7： | 30 |
| 3 | Therapeutic effect of acupuncture and massage for shoulder-hand syndrome in hemiplegia patients:a clinical two-center randomized controlled trial显示文摘OBJECTIVE:To evaluate the therapeutic effects of acupuncture and massage for shoulder-hand syndrome in hemiplegia patients.METHODS:One hundred and twenty hemiplegia patients with stage I shoulder-hand syndrome were randomly divided into a group treated with standardized electric acupuncture and massage,and a group treated with rehabilitation therapy for 6 weeks.The primary indices evaluated were pain on passive movement of the shoulder using the numeric pain rating scale(NPRS),and the number of patients with shoulder-hand syndrome at Steinbrocker stage II or III after treatment.The secondary indices were Fugl-Meyer evaluation of functional movement of the upper limb and hand using the modified rankin scale(MRS).RESULTS:At post-treatment evaluation and a 12-week follow-up visit,NPRS score,number of patients with stage II or III shoulder-hand syndrome,and MRS score were all improved in the acupuncture-massage group compared with the rehabilitation group(P<0.05).On Fugl-Meyer evaluation,functional movement of the upper limb was also improved in the acupuncture-massage group compared with the rehabilitation group(P<0.05).CONCLUSION:Standardized acupuncture-massage therapy may have curative effects on shoulder-hand syndrome in hemiplegia patients. | Ning Li Fengwei Tian Chengwei Wang Pengming Yu Xi Zhou Qian Wen Xiulan Qiao Lu Huang | 2012 | Journal of Traditional Chinese Medicine2012，32，3： | 25 |
| 4 | Pseudolaric acid B induces apoptosis,senescence,and mitotic arrest in human breast cancer MCF-7显示文摘目的:现在的学习的目的是在人的乳癌 MCF-7 cells.Methods:3-( 4,5-dimethylthiazol-2-yl )上调查 pseudolaric 酸 B ( PAB )的禁止的效果 -2,5-diphenyltetrazolium 溴化物分析,词法变化,染色的吖啶橙,并且统帅玫瑰胶化电气泳动被使用检测 apoptotic 的 apoptosis.The 百分比,坏死的房间被lactate 脱氢酶计算基于活动的细胞毒性试金;联系的老朽( SA ) -beta-galactosidase 活动被检测评估老朽; propidium 碘化物染色的流动 cytometric 分析被执行调查房间周期的分发,并且蛋白质表示被西方的污点 analysis.Results 检验:在 apoptosis 期间,半最大的禁止的集中 IC50 是在在 PAB 治疗以后的 36 和 48 h 的 3.4 和 1.35 亩 mol/L ,暴露于 PAB 的 respectively.The MCF-7 房间显示出 apoptosis 的典型特征,包括词法变化和 DNA 破碎。为 36 h 与 4 亩 mol/L PAB 对待的 MCF-7 房间经历了 apoptosis,然而并非坏死。PAB 导致的 apoptosis 独立于死亡受体小径。衰老的房间变得更大并且恭维,并且染色的 SA-p-galactosi-dase 是导致的 positive.PAB 明显的有丝分裂的拘捕和它先于 apoptosis 和老朽。p21 和 p53 的表情起来与 PAB 处理调整了,并且 cyclin B1 起来从细胞质调整了并且搬运,并且支撑了稳定的 levels.Conclusion 到原子核: PAB 在 MCF-7 房间导致了有丝分裂的拘捕并且通过 apoptosis 和老朽禁止了增长。apoptosis 独立于死亡受体小径。 | Jing-hua YU Qiao CUI Yuan-yuan JIANG Wei YANG Shin-ichi TASHIRO Satoshi ONODERA Takashi IKEJIMA | 2007 | Acta Pharmacologica Sinica2007，28，12： | 22 |
| 5 | The Aging Feature of Al-L-Cu-Mg-Zr Alloy Containing Sc显示文摘The aging behaviors of Al 1.42%Li 2.41%Cu 0.93%Mg 0.073%Zr 0.17%Sc(mass fraction, the same below) alloy at room temperature, 160 ℃ , and 160 ℃ after 8% pre deformation were studied respectively by hardness measurement. The microstructure of the alloy in various aging conditions was observed by TEM. The results show that the main precipitations of the alloy in quenching condition are the particles containing Sc and Zr which have certain coherent relation with the matrix. Addition of Sc in Al Li Cu Mg Zr alloy will be favorable to promoting precipitation. The particles can serve as preferred nucleation sites for δ′ phases which accelerate the aging hardening rate at initial aging. The main hardening phases of the alloy aged at 160 ℃ are δ′ and δ′/β′ composite precipitates. The size of the composite precipitates is very small (nanometer size). The composite precipitates will preclude efficiently the formation concentrative slip location and will improve the mechanical properties of the alloy. S′ phase will occur in the alloy aged at 160 ℃ after 8% pre deformation. It is found that 8% pre deformation has no obvious influence on the precipitation of the composite phase. | TAN Cheng yu,ZHENG Zi qiao,XIA Chang qing,LIANG Ying (Department of Materials Science and Engineering, Central South University of Technology, Changsha 410083, China) | 2000 | Journal of Central South University2000，12，2： | 22 |
| 6 | Plumbagin suppresses chronic periodontitis in rats via down-regulation of TNF-α, IL-1β and IL-6 expression显示文摘长期的 periodontitis (CP ) 是最普通的口头的疾病之一,它在成年人引起牙槽的骨头吸收和牙齿损失。在我们试图调查 plumbagin (PL ) 的潜力的这研究,广泛地调查的活跃混合物在对待 CP 从繁体中文植物石墨 zeylanica L 提取了。人的牙齿周围的系带干细胞(PDLSC ) 在 vitro 被用于研究,而 CP 的一个动物模型被 ligation+Porphyromonas gingivalis (Pg ) 在 SD 老鼠建立刺激。老鼠与 PL 被注射(2, 4,和 6 mgs。在这研究,我们建立了 biomarkers 的焦点模式描绘 Gegen Qinlian 煎(GQD ) 的剂量效果关系,为对待类型 2 糖尿病 mellitus (2-DM ) 的一个 TCM 公式。2-DM 的一个老鼠模型通过喂的饮食与低剂量的 STZ 注射相结合的高脂肪被建立。有 2-DM 的老鼠是管理高度,中间或低剂量(6.785, 4.071, 1.357 mgl/L ) 在 vitro 引起了 glomerular podocyte apoptosis,它被无毒的 chrysin (1-20 mol/L ) dose-dependently 通过 DNA 的减小稀释破碎。Chrysin 处理 dose-dependently 恢复了增加的 Bax/Bcl-2 比率,并且在高暴露葡萄糖的肾的 podocytes 压制了 Apaf-1 正式就职和提高的细胞色素 c 版本。在糖尿病的 db/db 老鼠, chrysin 的口头的管理(10 mgf 1.84 ??? ?? | Xin-yi ZHENG Chuan-yuan MAO Han QIAO Xi ZHANG Li YU Ting-yu WANG Er-yi LU | 2017 | Acta Pharmacologica Sinica2017，38，8： | 22 |
| 7 | Experimental investigation of laser peening on TiAl alloy microstructure and properties显示文摘In order to study the effect of laser peening on microstructures and properties of Ti Al alloy, Ti Al alloy samples were treated by Nd:YAG laser system with the wavelength of 1064 nm,pulse-width of 18 ns, and pulse-energy of 0–10 J. Surface micro-hardness, roughness, and microstructural characteristics were tested with micro-hardness tester, roughness tester and scanning electron microscope. Residual stress and pole figures were tested with X-ray diffraction and its high-temperature stability was analyzed. The experimental results show that surface micro-hardness increases by up to 30%, roughness increases to 0.37 lm, compressive residual stress increases to 337 MPa, and local texture and typical lamellar microstructure are generated. Residual stress, micro-hardness, and(002) pole figures tests are conducted, compressive residual stress value drops from 337 MPa to 260 MPa, hardness value drops from 377 HV_(0.2) to 343 HV_(0.2), and the(002)poles shift back to the center slightly. Laser peening improves microstructure and properties of Ti Al alloy significantly. | Qiao Hongchao Zhao Jibin Gao Yu | 2015 | Chinese Journal of Aeronautics2015，28，2： | 21 |
| 8 | ELASTIC MODULUS REDUCTION METHOD FOR LIMIT LOAD EVALUATION OF FRAME STRUCTURES显示文摘A new strategy for elastic modulus adjustment is proposed based on the element bearing ratio (EBR),and the elastic modulus reduction method (EMRM) is proposed for limit load evaluation of frame structures. The EBR is defined employing the generalized yield criterion,and the reference EBR is determined by introducing the extrema and the degree of uniformity of EBR in the structure. The elastic modulus in the element with an EBR greater than the reference one is reduced based on the linear elastic finite element analysis and the equilibrium of strain energy. The lower-bound of limit-loads of frame structures are analyzed and the numerical example demonstrates the flexibility,accuracy and effciency of the proposed method. | Lufeng Yang Bo Yu Yongping Qiao | 2009 | Acta Mechanica Solida Sinica2009，22，2： | 20 |
| 9 | The influence of plant root system architectural properties upon the stability of loess hillslopes,Northeast Qinghai,China显示文摘To investigate the influence of root system architectural properties of three indigenous(coldadapted) shrubs on the hillslope stability of loess deposits in the Xining Basin,northeast part of Qinghai-Tibet Plateau(QTP),indoor direct shear tests have been conducted on the remolded rooted soil of three shrubs.Test results show that root system architectural indices(root area ratio(RAR),root length density(RLD) and root density(RD)) of the shrubs decline with depth and the relationship between RAR,RD and depth is exponential,while a power relationship describes the relationship between RLD and depth.The cohesion force of remolded rooted soil for the shrubs initially increases withdepth,but it then demonstrates a slightly decreasing trend,which can be described with a power relationship.Power relationships also describe relationships between cohesion force and RAR,RLD and RD for the shrubs.As the growth period increases from 10 to 17 months,the incremental increase in RAR is 48.32% ~ 210.25% for Caragana korshinskii Kom and 0.56% ~ 166.85% for Zygophyllum xanthoxylon(Bunge) Maxim.This proportional increase is notably larger than that for RLD and RD.The increment in RAR is marginally greater for C.korshinskii than it is for Z.xanthoxylon.Correspondingly,the cohesion force incremental rates of remolded rooted soil for C.korshinskii and Z.xanthoxylon are 12.41% ~ 25.22% and 3.45% ~ 17.33% respectively.Meanwhile,as root content increases,the contribution by roots to cohesion force increases markedly until a threshold condition is reached. | FU Jiang-tao HU Xia-song BRIERLEY Gary QIAO Na YU Qin-qin LU Hai-jing LI Guo-rong ZHU Hai-li | 2016 | Journal of Mountain Science2016，13，5： | 18 |
| 10 | Effect of Nb on Mechanical Properties of HAZ for High-Nb X80 Pipeline Steels显示文摘The mechanical properties of heat affected zone(HAZ)of two commercial high-Nb X80grade pipeline steels with different alloy elements were investigated using thermal simulation performed on a Gleeble-3500thermal simulator.The results showed that the high-Nb steels have excellent weldability.Embrittlement regions appear in coarse grain heat affected zone(CGHAZ)and intercritically heat affected zone(ICHAZ);Softening region appears in fine-grain heat affected zone(FGHAZ),and the strength here was even lower than 555 MPa as required in the standard.Meanwhile,with the increase of heat input,the strength and the toughness of HAZ of steel with high Nb,C and lower alloy decrease notably.Therefore,take into account the welding procedure during manufacture of weld pipe,suitable amount of alloy elements,such as Cr,Ni,Cu,Mo and so on,is necessary for high Nb X80heavythick steel plate. | CHEN Xiao-wei LIAO Bo QIAO Gui-ying GU Yu WANG Xu XIAO Fu-ren | 2013 | Journal of Iron and Steel Research(International)2013，20，12： | 15 |
| 11 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015，27，1： | 14 |
| 12 | Efficacy and Safety of Tripterygium wilfordii Hook F Versus Acitretin in Moderate to Severe Psoriasis Vulgaris:A Randomized Clinical Trial显示文摘 | Chao Wu Hong-Zhong Jin Dan Shu Feng Li Chun-Xia He Ju Qiao Xiao-Ling Yu | 2015 | Chinese Medical Journal2015，，4： | 14 |
| 13 | Role of Fas/FasL Pathway-mediated Alveolar Macrophages Releasing Inflammatory Cytokines in Human Silicosis显示文摘The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied.It showed that the serum levels of IL-1β,TNF-α,IL-8,MIP-1α,MCP-1,and TGF-β1were higher in silicosis patients than in controls,and increased with the progression of silicosis except TGF-β1 and IL-8.TGF-β1,IL-8,MCP-1,MIP-1αwere efficiently down-regulated by anti-FasL antibody or caspase-8 inhibitor,indicating that Fas/FasL signaling promotes the | YAO San Qiao HE Qin Cheng YUAN Ju Xiang CHEN Jie CHEN Gang LU Yao BAI Yu Ping ZHANG Chun Min YUAN Yang XU Ying Jun | 2013 | Biomedical and Environmental Sciences2013，26，11： | 13 |
| 14 | Associations of big endothelin-1 and C-reactive protein in atrial fibrillation显示文摘 | Li-Hui ZHENG Wei SUN Yan YAO Bing-Bo HOU Yu QIAO Shu ZHANG | 2016 | Journal of Geriatric Cardiology2016，13，5： | 13 |
| 15 | Prognostic significance of preoperative and postoperative CK19 and CEA m RNA levels in peripheral blood of patients with gastric cardia cancer显示文摘AIM To evaluate the clinical and prognostic significance of preoperative and postoperative cytokeratin 19(CK19) and carcinoembryonic antigen(CEA) m RNA levels in peripheral blood of patients with gastric cardia cancer(GCC).METHODS We detected the preoperative and postoperative mR NA levels of CK19 and CEA in peripheral blood of 129 GCC patients by using reverse transcription-polymerase chain reaction and evaluated their clinical and prognostic significance by univariate Kaplan-Meier survival analysis and multivariate Cox proportional hazard analysis. A new prognostic model which stratified patients into three different risk groups was established based on the independent prognostic factors.RESULTS Elevated preoperative and postoperative CK19 and CEA mR NA levels in peripheral blood of GCC patients were associated with lymph node metastasis. Univariate analysis showed that tumor size, histological grade, depth of tumor invasion, lymph node metastasis, preoperative CK19 m RNA, and preoperative and postoperative CEA m RNA levels were correlated with the prognosis of GCC patients. The multivariate analysis showed that lymph node status(P = 0.018), preoperative CK19(P = 0.035) and CEA(P = 0.011) m RNA levels were independent prognostic factors for overall survival(OS). The 5-year OS rates for the low-, intermediate-, and high-risk groups were 48.3%, 22.6%, and 4.6%, respectively(P < 0.001).CONCLUSION Elevated preoperative CK19 and CEA mR NA levels may be regarded as promising biomarkers for predicting lymph node metastasis and poor prognosis in patients with GCC. This new prognostic model may help us identify the subpopulations of GCC patients with the highest risk. | Yu-Feng Qiao Chuan-Gui Chen Jie Yue Ming-Quan Ma Zhao Ma Zhen-Tao Yu | 2017 | World Journal of Gastroenterology2017，23，8： | 13 |
| 16 | A New Video Portable Intubationscope: A Clinical Evaluation of Its Efficacy and Safety of Intubation in Patients with General Anesthesia显示文摘 | Yu Zhou Wei Wang Rui-dong Qiao Ning Zhang Hong-hui Huang | 2012 | 麻醉与监护论坛2012，19，2： | 12 |
| 17 | Low-carbon transition of iron and steel industry in China:Carbon intensity, economic growth and policy intervention显示文摘As the biggest iron and steel producer in the world and one of the highest CO2 emission sectors, China's iron and steel industry is undergoing a low-carbon transition accompanied by remarkable technological progress and investment adjustment, in response to the macroeconomic climate and policy intervention. Many drivers of the CO2 emissions of the iron and steel industry have been explored, but the relationships between CO2 abatement,investment and technological expenditure, and their connections with the economic growth and governmental policies in China, have not been conjointly and empirically examined. We proposed a concise conceptual model and an econometric model to investigate this crucial question. The results of regression, Granger causality test and impulse response analysis indicated that technological expenditure can significantly reduce CO2 emissions, and that investment expansion showed a negative impact on CO2 emission reduction. It was also argued with empirical evidence that a good economic situation favored CO2 abatement in China's iron and steel industry, while achieving CO2 emission reduction in this industrial sector did not necessarily threaten economic growth.This shed light on the dispute over balancing emission cutting and economic growth.Regarding the policy aspects, the year 2000 was found to be an important turning point for policy evolution and the development of the iron and steel industry in China. The subsequent command and control policies had a significant, positive effect on CO2 abatement. | Bing Yu Xiao Li Yuanbo Qiao Lei Shi | 2015 | Journal of Environmental Sciences2015，27，2： | 12 |
| 18 | Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes显示文摘 | Qiaozhen Liu Rui Yang Xiuzhen Huang Hui Zhang Lingjuan He Libo Zhang Xueying Tian Yu Nie Shengshou Hu Yan Yan Li Zhang Zengyong Qiao Qing-Dong Wang Kathy O Lui Bin Zhou | 2016 | Cell Research2016，26，1： | 12 |
| 19 | Four new constituents from Taraxacum mongolicum显示文摘二新黄酮 glycosides ,isoetin-7-O-β- d-glucopyranosyl-2 ′- O -- l-arabinopyranoside ( 1 )和isoetin-7-O-β- d-glucopyranosyl-2 ′- O -- d-glucopyranoside ( 2 ),新 lignan , mongolicumin A ( 3 ),和新 guaianolide , mongolicumin B ( 4 )从薄公英属 mongolicum 的天线部分被孤立。他们的结构被主要阐明光谱分析。 | Shu Yun Shi Qi Zhou Hua Peng Chang Xin Zhou Ming Hui Hu Qiao Feng Tao Xiao Jiang Hao Joachim Stoeckigt Yu Zhao | 2007 | Chinese Chemical Letters2007，18，11： | 11 |
| 20 | Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs显示文摘干皮病 pigmentosum (XP ) 是联系 XP 的基因的变化引起的一组基因混乱,导致 DNA 修理的缺陷。XP 病人经常展出神经病学的退化,而是内在的机制是未知的,部分地由于合适的疾病模型的缺乏。这里,我们产生了包括 XPA, XPB, XPC, XPG,和 XPV 在五不同 XP 基因怀有变化的病人特定的导致的 pluripotent 干细胞(iPSCs ) 。这些 iPSCs 进一步被区分到神经房间,并且他们到 DNA 损坏应力的危险性被调查。在神经干细胞(NSC ) 或神经原的 XPA 的变化导致了严重 DNA 损坏修理缺点,并且有变异的 XPA 的这些神经房间对 DNA 导致损坏的 apoptosis 过分敏感。因此, XP 变异的神经房间代表珍贵工具在 XP 病人澄清神经病学的畸形的分子的机制。 | Lina Fu Xiuling Xu Ruotong Ren Jun Wu Weiqi Zhang Jiping Yang Xiaoqing Ren Si Wang Yang Zhao Liang Sun Yang Yu Zhaoxia Wang Ze Yang Yun Yuan Jie Qiao Juan Carlos Izpisua Belmonte Jing Qu Guang-Hui Liu | 2016 | Protein & Cell2016，7，3： | 11 |
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