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| 1 | Chronic ankle instability is associated with proprioception deficits:A systematic review and meta-analysis显示文摘Background:Acute ankle injury causes damage to joint mechanoreceptors and deafferentation and contributes to proprioception deficits in patients with chronic ankle instability(CAI).We aimed to explore whether deficits of proprioception,including kinesthesia and joint position sense(JPS),exist in patients with CAI when compared with the uninjured contralateral side and healthy people.We hypothesized that proprioception deficits did exist in patients with CAI and that the deficits varied by test methodologies.Methods:The study was a systematic review and meta-analysis.We identified studies that compared kinesthesia or JPS in patients with CAI with the uninjured contralateral side or with healthy controls.Meta-analyses were conducted for the studies with similar test procedures,and narrative syntheses were undertaken for the rest.Results:A total of 7731 studies were identified,of which 30 were included for review.A total of 21 studies were eligible for meta-analysis.Compared with the contralateral side,patients with CAI had ankle kinesthesia deficits in inversion and plantarflexion,with a standardized mean difference(SMD)of 0.41 and 0.92,respectively,and active and passive JPS deficits in inversion(SMD=0.92 and 0.72,respectively).Compared with healthy people,patients with CAI had ankle kinesthesia deficits in inversion and eversion(SMD=0.64 and 0.76,respectively),and active JPS deficits in inversion and eversion(SMD=1.00 and 4.82,respectively).Proprioception deficits in the knee and shoulder of patients with CAI were not statistically significant.Conclusion:Proprioception,including both kinesthesia and JPS,of the injured ankle of patients with CAI was impaired,compared with the uninjured contralateral limbs and healthy people.Proprioception varied depending on different movement directions and test methodologies.The use of more detailed measurements of proprioception and interventions for restoring the deficits are recommended in the clinical management of CAI. | Xiao’ao Xue Tengjia Ma Qianru Li Yujie Song Yinghui Hua | 2021 | Journal of Sport and Health Science2021，10，2： | 21 |
| 2 | Quantitative analyses of relationships between ecotoxicological effects and combined pollution显示文摘The responses of wheat Triticum aestivum, rice Oryza sativa, earthworms Eisenia foetida, and prawns Penaeus japonicus to combined acetochlor-Cu, Cd-Zn were studied in hy-droponic and soil-culturing systems using the methods of ecotoxicology. In particular, system-atically quantitative analyses were documented by field experiments. Results showed that ecotoxicological effects under the combined pollution were not only related to chemical proper-ties of pollutants but also dependent on the concentration level of pollutants, in particular on the combination of concentrations of pollutants in ecosystems. Additionally, species of organisms, especially the type of ecosystem, determined the influences. To some extent, biological tissue targets attacked by pollutants were an important factor. | ZHOU Qixing CHENG Yun ZHANG Qianru LIANG Jidong | 2004 | Science China(Life Sciences)2004，47，4： | 20 |
| 3 | Recent progress towards mild-condition ammonia synthesis显示文摘Ammonia is essential for food and energy.Industrial ammonia synthesis via Haber–Bosch process is energy-intensive and releases large amount of CO2.Increasing research efforts are devoted to 'green'ammonia synthesis.The present article reviews the recent progress in the fields of thermocatalytic, electrocatalytic, photocatalytic and chemical looping processes for dinitrogen reduction towards ammonia formation and discusses the challenges borne for mild-condition synthesis. | Qianru Wang Jianping Guo Ping Chen | 2019 | Journal of Energy Chemistry2019，28，9： | 13 |
| 4 | Single and joint effects of petroleum hydrocarbons and cadmium on the polychaete Perinereis aibuhitensis Grube显示文摘用集中坡度和联合污染物质暴露方法,单身者和关节在 polychaete Perinereis aibuhitensis Grube 上石油烃(PHC ) 和镉(Cd ) 完成,一生态地在河口的重点种类和沿海的环境,被调查了。结果显示到 P 的 PHC 的毒性。aibuhitensis 比对有机体的 Cd 的强壮。在答案在蠕虫的死亡和单个 Cd 或 PHC 的暴露的集中之间有正相关。同样,在蠕虫的 Cd 或 PHC 的累积与增加暴露 Cd 或暴露 PHC 的集中增加了。所有关联关系能用单一的二次的方程(Y 或 Z = aX2 + bX + c ) 被描述。它被计算,根据这些表情, P 的中部的致死剂量(LC50 ) 。暴露于单个 Cd 或 PHC 的 aibuhitensis 分别地是 793.4 13567.3 和 28.0 119.9 μ g /L。暴露的时间在二种污染物质上并且在蠕虫的死亡上有某刺激效果。因此,当暴露的时间变得更长时,甚至单个 Cd 或 PHC 的低集中可以在蠕虫上有强壮的有毒的效果。在蠕虫的 Cd 或 PHC 的累积在单个 Cd 或 PHC 的给定的暴露的集中随暴露时间的增加不同。显著地,在蠕虫的 PHC 的累积在答案在 PHC 的给定的高集中随暴露时间的增加减少。P 上的 PHC 和 Cd 的联合效果。aibuhitensis 是很复杂的并且随着二种污染物质的暴露的集中变化。在 PHC 的给定的集中,蠕虫上的二种污染物质的联合毒性随 Cd 集中的增加从协同改变到对抗。在蠕虫的 Cd 的累积显著地与暴露答案的 PHC 的增加减少。 | WANG Jing ZHOU Qixing ZHANG Qianru ZHANG Ying | 2008 | Journal of Environmental Sciences2008，20，1： | 12 |
| 5 | Influences of Cu or Cd on the neurotoxicity induced by petroleum hydrocarbons in ragworm Perinereis aibuhitensis显示文摘破布蠕虫上的重金属和石油烃(PHC ) 的 ecotoxicological 效果仍然是含糊的。在毒物学的索引(死亡和乙酰胆碱酯酶(疼痛) 活动) 和有毒物(Cu, Cd,和 PHC ) 的集中之间的关系处于实验室条件在河口重点种类 Perinereis aibuhitensis 被检验。单个有毒物的结果显示三有毒物有潜在地生理的毒性到 P。aibuhitensis。为 Cu, Cd,和 PHC 的估计的 4-d 和 10-d LC50 从在死亡和有毒物集中之间的关系被导出。在 P 的词法症状的著名变化。暴露于 PHC 的 aibuhitensis 被观察。P 的疼痛活动。aibuhitensis 比其它对 PHC 的毒性更敏感。联合有毒物的结果暗示到 P 的 Cu 或 Cd 和 PHC 的联合毒性。aibuhitensis 与有毒物的集中联合有关。比较了挑选 PHC 治疗, Cu 或 Cd 的增加显著地在 P 减轻了 PHC 的 neurotoxicity 到疼痛活动。aibuhitensis,它显示出对抗效果。 | ZHANG Qianru ZHOU Qixing WANG Jing SUN Shulan HUA Tao REN Liping | 2008 | Journal of Environmental Sciences2008，20，3： | 12 |
| 6 | Optimization of Agrobacterium tumefaciens-Mediated Transformation Systems in Tea Plant(Camellia sinensis)显示文摘In this study, an efficient plant regeneration protocol in vitro and transformation by Agrobacterium-mediated method of Camellia sinensis was achieved, which would lay the foundation for genetic improvement of tea plant by genetic engineering technology. The cotyledon callus of C.sinensis were used as the receptors for transformation by Agrobacterium tumefaciens EHA105 containing PS1aG-3. Some factors which affected the result of Agrobacterium-mediated transformation of C. sinensis were studied on the basis of GUS transient expression system. The optimum system of Agrobacterium-mediated transformation was that the cotyledon callus were pre-cultured for 3 d, and then infected by EHA105 for 15 min followed by 3 d co-culture in the dark on the YEB medium containing 150 μmol·L^(-1) acetosyringone(AS). The transient expression rate of GUS gene was 62.6%. After being delayed selective culture for 3 d, infected callus were transferred into the differentiation medium and the root induction medium both of which were supplemented with 100 mg·L^(-1) spectinomycin, and then resistant seedlings of C. sinensis were obtained. The conversion rate was 3.6%. | LV Qianru CHEN Changsong XU Yijuan HU Shunkai WANG Le SUN Kang CHEN Xuan LI Xinghui | 2017 | Horticultural Plant Journal2017，3，3： | 9 |
| 7 | Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome显示文摘Regulatory T(Treg) cells, a subtype of immunosuppressive CD4^+T cells, are vital for maintaining immune homeostasis in healthy people. Forkhead box protein P3(FOXP3), a member of the forkhead-wingedhelix family, is the pivotal transcriptional factor of Treg cells. The expression, post-translational modifications, and protein complex of FOXP3 present a great impact on the functional stability and immune plasticity of Treg cells in vivo. In particular, the mutation of FOXP3 can result in immune dysregulation,polyendocrinopathy, enteropathy, X-linked(IPEX) syndrome, which is a rare genetic disease mostly diagnosed in early childhood and can soon be fatal. IPEX syndrome is related to several manifestations,including dermatitis, enteropathy, type 1 diabetes, thyroiditis, and so on. Here, we summarize some recent findings on FOXP3 regulation and Treg cell function. We also review the current knowledge about the underlying mechanism of FOXP3 mutant-induced IPEX syndrome and some latest clinical prospects.At last, this review offers a novel insight into the role played by the FOXP3 complex in potential therapeutic applications in IPEX syndrome. | Qianru Huang Xu Liu Yujia Zhang Jingyao Huang Dan Li Bin Li | 2020 | Journal of Genetics and Genomics2020，47，1： | 8 |
| 8 | Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis显示文摘Curcumenol,an effective ingredient of Wenyujin,has been reported that exerted its antitumor potential in a few cancer types.However,the effect and molecular mechanism of curcumenol in lung cancer are largely unknown.Here,we found that curcumenol induced cell death and suppressed cell proliferation in lung cancer cells.Next,we demonstrated that ferroptosis was the predominant method that contributed to curcumenol-induced cell death of lung cancer in vitro and vivo for the first time.Subsequently,using RNA sequencing,we found that the long non-coding RNA H19(lncRNA H19)was significantly downregulated in lung cancer cells treated with curcumenol,when compared to untreated controls.Overexpression of lncRNA H19 eliminated the anticancer effect of curcumenol,while lncRNA H19 knockdown promoted ferroptosis induced by curcumenol treatment.Mechanistically,we showed that lncRNA H19 functioned as a competing endogenous RNA to bind to miR-19b-3p,thereby enhanced the transcription activity of its endogenous target,ferritin heavy chain 1(FTH1),a marker of ferroptosis.In conclusion,our data show that the natural product curcumenol exerted its antitumor effects on lung cancer by triggering ferroptosis,and the lncRNA H19/miR-19b-3p/FTH1 axis plays an essential role in curcumenol-induced ferroptotic cell death.Therefore,our findings will hopefully provide a valuable drug for treating lung cancer patients. | Ruonan Zhang Ting Pan Yu Xiang Mingming Zhang Han Xie Zimao Liang Bi Chen Cong Xu Jing Wang Xingxing Huang Qianru Zhu Ziming Zhao Quan Gao Chengyong Wen Wencheng Liu Weirui Ma Jiao Feng Xueni Sun Ting Duan Elaine Lai-Han Leung Tian Xie Qibiao Wu Xinbing Sui | 2022 | Bioactive Materials2022，7，7： | 8 |
| 9 | Overview of Relation between Mineral Nutrient Elements and Growth and Development of Fruit Trees显示文摘Mineral nutrition is the material basis for growth and development,yield and quality of fruit trees. It exerts a great effect on the growth and development,fruit quality,yield,and resistance of fruit trees. On the basis of reading a large number of references both at home and abroad,this paper elaborated the relationship between mineral nutrient elements and growth and fruit yield and quality of fruit trees,so as to make proper fertilizer mixing,balance the fertilizer application,promote growth and development of fruit trees,and increase the yield of fruit trees and improve the fruit quality. | Liping HUANG Qianru ZHANG Zheng ZHANG Rong YIN Jing ZHANG Ping YANG | 2017 | Asian Agricultural Research2017，9，10： | 7 |
| 10 | Transcriptomic analyses identify albino-associated genes of a novel albino tea germplasm ‘Huabai 1’显示文摘Albinism in shoots of tea plants is a common phenotypic expression which gives the tea infusion a pleasant umami taste.A novel natural albino mutant tea germplasm containing high amino acids content was found and named as‘Huabai 1’.‘Huabai 1’has white jade tender shoots under low temperature and turns green with increased temperature.In order to understand the molecular mechanism of color change in leaf of‘Huabai 1’,transcriptome analysis was performed to identify albino-associated differentially expressed genes(DEGs).A total of 483 DEGs were identified from white shoots of‘Huabai 1’compared to its green shoots.There were 15 DEGs identified to be involved in phenylpropanoid biosynthesis,which account for the majority of characterized DEGs.The metabolites related to phenylpropanoid biosynthesis revealed similar expression pattern of DEGs.Furthermore,metabolic pathways such as ubiquonone,tyrosine,and flavonoid biosynthesis associated with phenylpropanoid biosynthesis could also contribute to the color change in‘Huabai 1’tender shoots.Protein–protein interaction analysis revealed a hub protein NEDD8(CSA009575)which interacted with many regulated genes in spliceosome,nitrogen metabolism,phenylpropanoid biosynthesis,and other pathways.In conclusion,the findings in this study indicate that the color change of‘Huabai 1’tender shoots is a combined effect of phenylpropanoid biosynthesis pathway and other metabolic pathways including flavonoid biosynthesis in tea plants.Chlorophyll biosynthesis-related genes LHCII and SGR may also play some roles in color change of‘Huabai 1’. | Qingping Ma Huan Li Zhongwei Zou Emmanuel Arkorful Qianru Lv Qiongqiong Zhou Xuan Chen Kang Sun Xinghui Li | 2018 | Horticulture Research2018，5，1： | 7 |
| 11 | Dendrite‐free lithium and sodium metal anodes with deep plating/stripping properties for lithium and sodium batteries显示文摘Although lithium(Li)and sodium(Na)metals can be selected as the promising anode materials for next‐generation rechargeable batteries of high energy density,their practical applications are greatly restricted by the uncontrollable dendrite growth.Herein,a platinum(Pt)–copper(Cu)alloycoated Cu foam(Pt–Cu foam)is prepared and then used as the substrate for Li and Na metal anodes.Owing to the ultrarough morphology with a threedimensional porous structure and the quite large surface area as well as lithiophilicity and sodiophilicity,both Li and Na dendrite growths are significantly suppressed on the substrate.Moreover,during Li plating,the lithiated Pt atoms can dissolve into Li phase,leaving a lot of microsized holes on the substrate.During Na plating,although the sodiated Pt atoms cannot dissolve into Na phase,the sodiation of Pt atoms elevates many microsized blocks above the current collector.Either the holes or the voids on the surface of Pt–Cu foam what can be extra place for deposited alkali metal,what effectively relaxes the internal stress caused by the volume exchange during Li and Na plating/stripping.Therefore,the symmetric batteries of Li@Pt–Cu foam and Na@Pt–Cu foam have both achieved long‐term cycling stability even at ultrahigh areal capacity at 20 mAh cm−2. | Jianyi Wang Qi Kang Jingchao Yuan Qianru Fu Chunhua Chen Zibo Zhai Yang Liu Wei Yan Aijun Li Jiujun Zhang | 2021 | Carbon Energy2021，3，1： | 6 |
| 12 | Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells显示文摘T cells react to foreign or self-antigens through T cell receptor(TCR)signaling.Several decades of research have delineated the mechanism of TCR signal transduction and its impact on T cell performance.This knowledge provides the foundation for chimeric antigen receptor T cell(CAR-T cell)technology,by which T cells are redirected in a major histocompatibility complex-unrestricted manner.TCR and CAR signaling plays a critical role in determining the T cell state,including exhaustion and memory.Given its artificial nature,CARs might affect or rewire signaling differently than TCRs.A better understanding of CAR signal transduction would greatly facilitate improvements to CAR-T cell technology and advance its usefulness in clinical practice.Herein,we systematically review the knowns and unknowns of TCR and CAR signaling,from the contact of receptors and antigens,proximal signaling,immunological synapse formation,and late signaling outcomes.Signaling through different T cell subtypes and how signaling is translated into practice are also discussed. | Ling Wu Qianru Wei Joanna Brzostek Nicholas R.J.Gascoigne | 2020 | Cellular & Molecular Immunology2020，17，6： | 6 |
| 13 | Colorectal cancer burden,trends and risk factors in China:A review and comparison with the United States显示文摘Objective:China and the United States(the U.S.)have the heaviest colorectal cancer(CRC)burden with considerable variations in temporal trends.This study aims to analyze the temporal patterns of CRC burden and its risk factors in China and the U.S.across the past three decades.Methods:Data were extracted from the Global Burden of Disease(GBD)Study in 2019,including cases,deaths,disability-adjusted life-years(DALYs),age-standardized rate(ASR),and summary exposure value(SEV)of CRC in China and the U.S.between 1990 and 2019.Annual average percentage changes(AAPCs)of CRC burden were calculated using the Joinpoint regression model.The mortality in CRC attributable to potential risk factors was characterized by countries,gender,and age groups.Results:In 2019,there were 607,900 and 227,241 CRC cases,and 261,777 and 84,026 CRC deaths in China and the U.S.,respectively.The age-standardized incidence rate(ASIR)was 30.55 per 100,000 in China and 41.86 per100,000 in the U.S.,and the age-standardized mortality rate(ASMR)was 13.86 per 100,000 in China and 14.77 per100,000 in the U.S.CRC incidence,mortality,and DALY rate in the U.S.showed downward trends in the past three decades(AAPC=-0.47,-1.06,and-0.88,respectively),while upward trends were observed in China(AAPC=3.11,1.05,and 0.91,respectively).Among the cause of CRC,the leading risk factor contributing to CRC death was low milk in China and smoking in the U.S.,respectively.Conclusions:From 1990 to 2019,the burden of CRC in China increased dramatically,particularly for males and middle-aged and elderly people.The management of the major risk factors associated with the high burden of CRC should be enhanced. | Qianru Li Hongliang Wu Maomao Cao He Li Siyi He Fan Yang Xinxin Yan Shaoli Zhang Yi Teng Changfa Xia Ji Peng Wanqing Chen | 2022 | Chinese Journal of Cancer Research2022，34，5： | 6 |
| 14 | First Discovery and Zircon U-Pb Dating of Early Ordovician Granitoids in Lincang Batholith, Western Yunnan: Implications for the Presence of Proto-Tethyan Orogeny in the Sanjiang Region, SW China显示文摘Objective The Lincang granitic batholith,extending over 370 km from north to south with an area of more than 10000 km^2,is the major part of the Sanjiang region in western Yunnan,SW China,and is one key area to study the evolution of the Tethys.Previous studies all agreed that the Lincang batholith was formed in the Triassic。 | XIAO Qianru XIONG Fuhao ZHAO Han FENG Xiujun WANG Qiang XIAO Yuanfu | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 6 |
| 15 | A static technique for detecting input validation vulnerabilities in Android apps显示文摘Input validation vulnerabilities are common in Android apps, especially in inter-component communications. Malicious attacks can exploit this kind of vulnerability to bypass Android security mechanism and compromise the integrity, confidentiality and availability of Android devices. However, so far there is not a sound approach at the source code level for app developers aiming to detect input validation vulnerabilities in Android apps. In this paper, we propose a novel approach for detecting input validation flaws in Android apps and we implement a prototype named Easy IVD, which provides practical static analysis of Java source code.Easy IVD leverages backward program slicing to extract transaction and constraint slices from Java source code.Then Easy IVD validates these slices with predefined security rules to detect vulnerabilities in a known pattern.To detect vulnerabilities in an unknown pattern, Easy IVD extracts implicit security specifications as frequent patterns from the duplicated slices and verifies them. Then Easy IVD semi-automatically confirms the suspicious rule violations and reports the confirmed ones as vulnerabilities. We evaluate Easy IVD on four versions of original Android apps spanning from version 2.2 to 5.0. It detects 58 vulnerabilities including confused deputy attacks and denial of service attacks. Our results prove that Easy IVD can provide a practical defensive solution for app developers. | Zhejun FANG Qixu LIU Yuqing ZHANG Kai WANG Zhiqiang WANG Qianru WU | 2017 | Science China(Information Sciences)2017，60，5： | 5 |
| 16 | Real-time dynamic system to path tracking and collision avoidance for redundant robotic arms显示文摘An dynamic system for real-time obstacle avoidance path planning of redundant robots is constructed in this paper. Firstly, the inter-frame difference method is used to identify the moving target and to calculate the target area, then on the basis of color features and gradient features extracted from the target area, the feature fusion Cam-Shift mean shift algorithm is used to track target, improving the robustness of the tracking algorithm. Secondly, a parallel two-channel target identification and location method based on binocular vision is proposed, updating the target's three-dimensional information in real time. Then, a dynamic collision-free path planning method is implemented: the safety rods are removed through the intersection test, and the minimum distance is derived directly by using the coordinate values of the target in the local coordinate system of the rod. On this basis, the obstacle avoidance gain and escape velocity related to the minimum distance is established, and obstacle avoidance path planning is implemented by using the zero space mapping matrix of redundant robot. Experiments are performed to study the efficiency of the proposed system. | Gao Xin Jia Qingxuan Sun Hanxu Chen Gang Zhang Qianru Yang Yukun | 2016 | The Journal of China Universities of Posts and Telecommunications2016，23，1： | 5 |
| 17 | Characteristic analysis of phospholipid fatty acids (PLFAs) in typical nutrient polluted lake sediment in Wuhan显示文摘The process of urbanization aggravates the endogenous pollution of urban lake sediment,and polluted sediment may seriously affect the quality of the water in lakes.At present,it is difficult to distinguish the difference between sediment that is heavily polluted by nitrogen(N)and phosphorus(P)when using an analysis based on a physicochemical index classification.The current study applied phospholipid fatty acid(PLFA)technology to further analyze the sediment characteristics from the perspective of microbiology.Surface sediment from five urban lakes that are heavily polluted with N and P in Wuhan were sampled.Statistical approaches were used to analyze the microbial community structure in the sampled sediment,and to determine the correlations between the microorganisms and physicochemical indices.The most severely polluted lake sediment had similar PLFA structures,the highest saturated fatty-acid content,and bacteria as the dominant microorganism.However,there were differences between the microbial biomass of the various sediment samples,which may have been related to the degree of N and P pollution.Analysis of the microbial diversity in the sediment samples indicated that the bacteria were experiencing starvation and nutrient pressure,which may have been due to the dissolved oxygen concentration of the heavily polluted lake sediment.A correlation analysis showed that the endogenous N and P had different effects on the microbes of the polluted sediment.A redundancy analysis(RDA)demonstrated that the N/P ratio had the greatest influence on the PLFA species,accounting for 83%of the cumulative interpretation.To effectively promote the role of sediment microorganisms on circulating elements,it is necessary to regulate the N/P ratio of the sediment to some extent.When the N/P ratio in sediment exceeds 6,N pollution should be prioritized. | Xia Zhang Qianru Chen Chuan Wang Hongpei Zhang Yuqing Zhao Liping Zhang Biyun Liu Zhenbin Wu Qiaohong Zhou | 2021 | International Journal of Sediment Research2021，36，2： | 5 |
| 18 | OsbZIP76 interacts with OsNF-YBs and regulates endosperm cellularization in rice (Oryza sativa)显示文摘Following double fertilization,plant endosperm nuclei undergo syncytial divisions,followed by synchro-nous cellularization.Cellularization is a key event during endosperm development,but our understanding of its regulation is limited to Arabidopsis.In this study we show that OsbZIP76 regulates cellularization in rice(Oryza sativa).Activation of OsbZIP76 coincided with the initiation of cellularization,and its knockdown or knockout mutants exhibited precocious cellularization.Genes involved in en-dosperm development or starch biosynthesis were pre-maturely activated in the osbzip76 caryopsis.As a putative transcription factor,OsbZIP76 alone lacked transcriptional activation activity;however,it interacted with the nuclear factor Y(NF-Y)family transcription factors OsNF-YB9 and OsNF-YB1 in yeast and in planta.OsbZIP76 and OsNF-YB9 were predominantly expressed in the endosperm and the proteins colocalized.Seeds of osnf-yb1 and osbzip76 mu-tants showed reduced size and reduced apparent amylose content.The parent-of-origin-dependent expression of OsbZIP76 is variable in different rice accessions.In sum-mary,OsbZIP76 is an endosperm-expressed imprinted gene that regulates endosperm development in rice. | Baixiao Niu Hui Deng Tingting Li Sandeep Sharma Qianbin Yun Qianru Li Zhiguo E Chen Chen | 2020 | Journal of Integrative Plant Biology2020，62，12： | 4 |
| 19 | Stomach cancer burden in China: Epidemiology and prevention显示文摘In 2020, stomach cancer was the fifth most commonly diagnosed cancer and the fourth leading cause of cancer-related death worldwide. Due to the relatively huge population base and the poor survival rate, stomach cancer is still a threat in China, and accounts for nearly half of the cases worldwide. Fortunately, in China, the incidence and mortality rates of stomach cancer presented a declining trend owing to the change of individual life styles and the persistent efforts to prevent stomach cancer from the governments at all levels. Helicobacter pylori(H. pylori)infection, poor eating habits, smoking, history of gastrointestinal disorders, and family history of stomach cancer are the main risk factors for stomach cancer in China. As a result, by taking risk factors for stomach cancer into account, specific preventive measures, such as eradicating H. pylori and implementing stomach cancer screening projects, should be taken to better prevent and decrease the burden of stomach cancer. | Xinxin Yan Lin Lei He Li Maomao Cao Fan Yang Siyi He Shaoli Zhang Yi Teng Qianru Li Changfa Xia Wanqing Chen | 2023 | Chinese Journal of Cancer Research2023，35，2： | 2 |
| 20 | Sympathetic Nerve Mediated Spinal Glia Activation Underlies Itch in a Cutaneous T-Cell Lymphoma Model显示文摘Dear Editor,Cancer-associated itch can be described as pruritus associated with malignancy.Although intractable itch associated with specific types of cancer afflicts patients badly,few effective treatments are available due to limited knowledge about the mechanisms of such itch.Globally,cancer-associated itch is an uncommon symptomin malignancy. | Fang Tong Qianru He Wan-Jie Du Huan Yang Dongping Du Shaofeng Pu Qingjian Han | 2022 | Neuroscience Bulletin2022，38，4： | 2 |
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