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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 血管性认知障碍的诊断标准:国际血管性行为与认知障碍学会的申明显示文摘长期以来,脑血管病(CVD)就被认为是认知损害的一个重要原因,但是有关脑血管病后认知障碍的概念化却有着一段多变的历史。'动脉变硬'或脑的动脉粥样硬化是'老化'的原因,是存在已久的观点,在20世纪60年代受到了来自英格兰纽卡斯尔的神经病理学研究的质疑。这些研究表明,血管性痴呆(vascular dementia,Va D)与超过一定程度的多发性脑梗死有关。 | 徐岩 郭起浩 Sachdev P Kalaria R O'Brien J Skoog I Alladi S Black SE Blacker D Blazer DG Chen C Chui H Ganguli M Jellinger K Jeste DV Pasquier F Paulsen J Prins N Rockwood K Roman G Scheltens P | 2014 | 神经病学与神经康复学杂志2014，11，3： | 19 |
| 3 | A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris显示文摘 | Jungo C Schenk J Pasquier M | 2007 | J Biotechnol2007，131，1： | 1 |
| 4 | Chemical fingerprinting of unevaporated automotive gasoline samples 显示文摘 | SANDERCOCK P M L PASQUIER E Du | 2004 | Forensic Science International2004，140，： | 1 |
| 5 | Class Ⅲ beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer显示文摘 | Gan P P Pasquier E Kavallaris M | | 0，，19： | 1 |
| 6 | Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer显示文摘 | Gan PP Pasquier E Kavallaris M | 2007 | Cancer Res2007，67，19： | 1 |
| 7 | Class Ⅲ beta-tubulin mediates sensitivity to chemotherapeutic drugs in non-small cell lung cancer显示文摘 | Gan PP Pasquier E Kavallaris M | | 0，，19： | 1 |
| 8 | Chordoid glioma of the third ventricle:a report of two new cases,with further evidence supporting an ependymal differentiation,and review of the literature显示文摘 | Pasquier B Peoch M Morrison AL | 2002 | Am J Surg Pathot2002，26，10： | 1 |
| 9 | Neonatal outcomes after elective delivery management of preterm premature rupture of the membranes before 34 weeks gestation (DOMINOS study)显示文摘 | Pasquier JC Picaud JC Rabilloud M | 2009 | Eur J Obstet Gynecol Reprod Biol2009，143，： | 1 |
| 10 | Surgical pathology of drug-resistent partial epilepsy:a10-year experience with a series of 327 consecutiveresections显示文摘 | Pasquier B Peoc' h M Fabre-Bocquentin B | 2002 | Epileptic Disorder2002，4，： | 1 |
| 11 | Premature ovarian failure显示文摘 | Christin-Maitre S Pasquier M Donadille B | 2006 | Ann Endocrinol:Paris2006，67，6： | 1 |
| 12 | Immunoreceptor tyrosinebased inhibition motifs: a quest in the past and future 显示文摘 | Da6ron M Jaeger S Du Pasquier L | 2008 | Immunol Rev2008，224，： | 1 |
| 13 | Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and re- view of the literature 显示文摘 | Pasquier B Peoc' h M Morrison AL | 2002 | Am J Surg Pathol2002，26，10： | 1 |
| 14 | Total knee arthroplasty in valgus knees:predictive preoperative parameters in uencing a con-strained design selection显示文摘 | Girard J Amzal ag M Pasquier G | | 0，，04： | 1 |
| 15 | Microtubules: a dynamic target in cancer therapy 显示文摘 | Pasquier E Kavallaris M | 2008 | IUBMB Life2008，60，3： | 1 |
| 16 | Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway 显示文摘 | Pasquier E Carré M Pourroy B | 2004 | Mol Cancer Ther2004，3，10： | 1 |
| 17 | Neonatal outcomes after elective delivery management of preterm premature rupture of the membranes before 34 week' s gestation ( DOMINOS study ) 显示文摘 | Pasquier JC Picaud JC Rabilloud M | 2009 | Eur J Obstet Gynecol Reprod Biol2009，，143： | 1 |
| 18 | Immunoreceptor tyrosine?based inhibition motifs: a quest in the past and future显示文摘 | Daeron M Jaeger S Du Pasquier L | 2008 | Immunol Rev2008，224，1： | 1 |
| 19 | Class m beta-tubulin mediates sensitivity to chemotherapeutic drugs in non- small cell lung cancer 显示文摘 | Gan PP Pasquier E Kavallaris M | 2007 | Cancer Res2007，67，19： | 1 |
| 20 | Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents:implication in breast cancer treatment显示文摘 | Pasquier E Ciccolini J Carre M | | 0，，10： | 1 |
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