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| 1 | The Integrator complex controls the termination of transcription at diverse classes of gene targets显示文摘包含 INTS3 和 NABP1 或 NABP2 的建筑群开始在 DNA 损坏回答被描绘,但是他们的生物化学的功能仍然保持未知。用亲密关系纯化和 HIV 集成定序目标(HIT-Seq ) ,我们发现这些建筑群是综合者建筑群的部分,它绑 RNA 聚合酶 II 并且调整特定的目标基因。综合者作为他们在亲密地被结合的机制处理到他们的成熟形式的部分劈开 snRNAs 抄写结束。然而, HIT-Seq 表明那个综合者也绑在 3 ′以 polyadenylated 抄本复制依赖者 histones 和倡导者结束基因的近似区域。综合者子单元的弄空导致抄写结束失败, histone mRNA 处理的混乱,和 snRNAs 和 histone mRNAs 的 polyadenylation。而且,倡导者综合者的近似绑定否定地通常调整其抄本是的基因的表示 polyadenylated。到所有三个基因类的综合者招募是 DSIF 依赖的,建议那个综合者作为在 DSIF 依赖的 RNA 聚合酶 II 的结束建筑群工作暂停地点。 | Jeffrey R Skaar Andrea L Ferris Xiaolin Wu Anita Saraf Kum Kum Khanna Laurence Florens Michael P Washburn Stephen H Hughes Michele Pagano | 2015 | Cell Research2015，25，3： | 2 |
| 2 | Competition between fusion-evaporation and multifragmentation in central collisions in ^(58)Ni+^(48)Ca at 25A MeV显示文摘The experimental data concerning the58Ni+48Ca reaction at Elab(Ni)=25A MeV,collected by using the CHIMERA 4π device,have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain.As a main criterion for centrality selection we have chosen the flow angle(flow) method,making an event-by-event analysis that considers the shape of events,as it is determined by the eigenvectors of the experimental kinetic-energy tensor.For the selected central events(flow >60°) some global variables,good to characterize the pattern of central collisions have been constructed.The main features of the reaction products were explored by using different constraints on some of the relevant observables,like mass and velocity distributions and their correlations.Much emphasis was devoted,for central collisions,to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a possible multifragmentation mechanism of a well defined(if any) transient nuclear system.Dynamical evolution of the system and pre-equilibrium emission were taken into account by simulating the reactions in the framework of transport theories.Different approaches have been envisaged(dynamical stochastic BNV calculations + sequential SIMON code,QMD,CoMD,etc.).Preliminary comparison of the experimental data with BNV calculations shows reasonable agreement with the assumption of sequential multifragmentation emission in the mass region of IMFs close to the heavy residues.Possible deviations from sequential processes were found for those IMFs in the region of masses intermediate between the mass of heavy residues and the mass of light IMFs.Further simulations are in progress.The experimental analysis will be enriched also by information obtained inspecting the IMF-IMF correlation function,in order to elucidated the nature of space-time decay property of the emitting source associated with events having the largest IMF multiplicity. | FRANCALANZA L ABBONDANNO U AMORINI F BARLINI S BINI M BOUGAULT R BRUNO M CARDELLA G CASINI G AGOSTINO M D' De FILIPPO V De SANCTIS J GERACI E GIUSSANI A GRAMEGNA F GUIOT B KRAVCHUK V La GUIDARA E LANZALONE G Le NEINDRE N MAIOLINO C MARINI P MORELLI L OLMI A PAGANO A PAPA M PIANTELLI S PIRRONE S POLITI G POGGI G PORTO F RUSSOTTO P RIZZO F VANNINI G VANNUCCI L | 2013 | Nuclear Science and Techniques2013，24，5： | 2 |
| 3 | The epiderniology of fungal infections in patients with hematologic malignancies : the SE1FEM - 2004 study显示文摘 | Pagano L Caira M Candoni A | 2006 | Haematologica2006，91，8： | 1 |
| 4 | Incidence and susceptibility to therapy- related myeloid neoplasms 显示文摘 | Leone G Fianchi L Pagano L | 2010 | Chem Biol Interact2010，184，12： | 1 |
| 5 | Regulation of the G1/S transition by the ubiquitin pathway显示文摘 | DeSalle L Pagano M | 2001 | FEBS Lett2001，490，1： | 1 |
| 6 | Current therapeutic ap- proaches to fungal infections in immunocompromised hematologi- cal patients显示文摘 | Pagano L Caira M Valentini CG | 2010 | Blood Rev2010，24，2： | 1 |
| 7 | bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mito- ehondria-dependent pathway 显示文摘 | Memailler-Ruchonnet l Pagano A Camesecchi S | 2007 | Free Radic Biol Med2007，42，7： | 1 |
| 8 | Zygomycosis in Europe: Analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007 显示文摘 | Skiada A Pagano L Groll A | 2011 | Clin Microbiol infect2011，17，12： | 1 |
| 9 | Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the Eu- ropean Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007显示文摘 | SKIADA A PAGANO L GROLL A | 2011 | Clin Micro- biol Infect2011，7，12： | 1 |
| 10 | Why do companies go public显示文摘 | Pagano M Panetta F Zingales L | | 0，，01： | 1 |
| 11 | Pneumocystis carinii pneumonia in patients with malignant haematological diseases:10 years' experience of infection in GIMEMA centres显示文摘 | Pagano L Fianchi L Mele L | | 0，，02： | 1 |
| 12 | Zygomycosis in Europe:analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007显示文摘 | Skiada A Pagano L Groll A | | 0，，12： | 1 |
| 13 | The epidemiology of fungal infections in patients with hematologic malignancies:the SEIFEM-2004 study显示文摘 | Pagano L Caira M Candoni A | | 0，，08： | 1 |
| 14 | Hypopituitarism following brair injury:when does it occur and how best to test? 显示文摘 | Gasco V Prodam F Pagano L | 2012 | Pituitary2012，15，1： | 1 |
| 15 | Blastic plasmaeytoid dendritic cell neoplasmwith leukemic presentation: an Italian muhieenter study显示文摘 | Pagano L Valentini C G Pulsoni A | 2013 | Haematologica2013，98，2： | 1 |
| 16 | The epidemiology of fungal infections in patients with hematologic malignancies: the SEIFEM- 2004 Study显示文摘 | Pagano L Caira M Candoni A | 2006 | Haematologica/Hematol J2006，91，10： | 1 |
| 17 | Follicular origin of a subset of CD5 + diffuse large B-cell lymphomas显示文摘 | Manazza AD Bonello L Pagano M | 2005 | Am J Clin Pathol2005，124，2： | 1 |
| 18 | Diurnal changes in serum triglycerides as related to changes in lipolytic enzymes, apolipoproteins and hormones in normal subjects on a carbohydrate-rich diet显示文摘 | PAGANO M O HAVEKES L TERPSTRA J | 1983 | Eur J Clin Invest1983，13，： | 1 |
| 19 | Therapy-related leukemia and myIodysplasia : susceptibility and incidence 显示文摘 | Leone G Pagano L Ben-yehuda D | 2007 | Haematologica2007，92，10： | 1 |
| 20 | PCR-restriction enzyme analysis for detection of Candida DNA, in blood from febrile patients with hematological malignancies显示文摘 | Morance G Pagano L Sanguinetti M | 1999 | J Clin Microbiol1999，37，6： | 1 |
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