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| 1 | Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection显示文摘 | Andrea J.Patterson RobertoColangeli PatriziaSpigaglia Karen P.Scott | 2006 | Environmental Microbiology2006，，3： | 1 |
| 2 | Postpartum seizure prophylaxis: using maternal clinical parameters to guide therapy显示文摘 | Christy M Isler P.Scott Barrilleaux Brian K Rinehart Everett F Magann James N Martin | 2003 | Obstetrics & Gynecology2003，，： | 1 |
| 3 | The relationships between stocking density and welfare in farmed rainbow trout显示文摘 | T.Ellis B.North A. P.Scott N.R.Bromage M.Porter D.Gadd | 2005 | Journal of Fish Biology2005，，3： | 1 |
| 4 | QAUST:Protein Function Prediction Using Structure Similarity,Protein Interaction,and Functional Motifs显示文摘The number of available protein sequences in public databases is increasing exponentially.However,a sig-nificant percentage of these sequences lack functional annotation,which is essential for the understanding of how bio-logical systems operate.Here,we propose a novel method,Quantitative Annotation of Unknown STructure(QAUST),to infer protein functions,specifically Gene Ontology(GO)terms and Enzyme Commission(EC)numbers.QAUST uses three sources of information:structure information encoded by global and local structure similarity search,biological network information inferred by protein–protein interaction data,and sequence information extracted from functionally discriminative sequence motifs.These three pieces of information are combined by consensus averaging to make the final prediction.Our approach has been tested on 500 protein targets from the Critical Assessment of Functional Annotation(CAFA)benchmark set.The results show that our method provides accurate functional annotation and outperforms other prediction methods based on sequence similarity search or threading.We further demonstrate that a previously unknown function of human tripartite motif-containing 22(TRIM22)protein predicted by QAUST can be experimentally validated. | Fatima Zohra Smaili Shuye Tian Ambrish Roy Meshari Alazmi Stefan T.Arold Srayanta Mukherjee P.Scott Hefty Wei Chen Xin Gao | 2021 | Genomics, Proteomics & Bioinformatics2021，19，6： | 0 |
| 5 | Heterogeneous 2D/3D photonic integrated microsystems显示文摘The continuing trend of exponential growth in data communications and processing are driving the need for large-scale heterogeneous integration.Similar to the trend we have observed in electronic integrated circuit development,we are witnessing a growing trend in 3D photonic integrated circuits(PICs)development in addition to that in 2D PICs.There are two main methods for fabricating 3D PICs.The first method,which utilizes ultrafast laser inscription(ULI),offers freeform shaping of waveguides in arbitrary contours and formations.The second method,which utilizes multilayer stacking and coupling of planar PICs,exploits relatively mature 2D PIC fabrication processes applied to each layer sequentially.Both the fabrication methods for 3D PICs have advantages and disadvantages such that certain applications may favor one method over the other.However,a joining of 2D PICs with 3D PICs can help develop integrated microsystems with new functionalities such as non-mechanical beam steering,spacedivision multiplexing(SDM),programmable arbitrary beam shaping,and photonic signal processing.We discuss examples of 3D PICs and 2D/3D integrated PICs in two applications:SDM via orbital-angular-momentum(OAM)multiplexing/demultiplexing and optical beam steering using optical phased arrays.Although a 2D PIC by itself can function as an OAM multiplexer or demultiplexer,it has limitations in supporting both polarizations.Alternatively,a 3D PIC fabricated by ULI can easily support both polarizations with low propagation loss.A combination of a 3D PIC and a 2D PIC designed and fabricated for OAM applications has successfully multiplexed and demultiplexed 15 OAM states to demonstrate polarization-diversified SDM coherent optical communications using multiple OAM states.Coherent excitation of multi-ring OAM states can allow highly scalable SDM utilizing Laguerre–Gaussian modes or linearly polarized(LP)modes.The preliminary fabrication of multi-ring OAM multiplexers and demultiplexers using the multilayer 3D PIC method and the ULI 3D PIC method has also been pursued.Large-scale(for example,16×16 optical phased array)3D PICs fabricated with the ULI technique have been demonstrated.Through these examples,we show that heterogeneous 2D/3D photonic integration retains the advantages of 2D PICs and 3D waveguides,which can potentially benefit many other applications. | S.J.Ben Yoo Binbin Guan Ryan P.Scott | 2016 | Microsystems & Nanoengineering2016，2，1： | 0 |
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