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5篇 您的检索式:作者名="NiXIE"
    题名 作者 年代 出处 被引量
1Positive effects of treatment of donor cells with aphidicolin on the preimplantation development of somatic cell nuclear transfer embryos in Chinese Bama mini‐pig (Sus Scrofa)显示文摘Ting‐YuZHANG Jian‐JunDAI Cai‐FengWU Xiao‐LongGU LiangLIU Zhi‐QiangWU Yi‐ NiXIE BinWU Hui‐LanCHEN YaoLI Xue‐JinCHEN De‐FuZHANG 2012Animal Science Journal2012,,2:1
2PreparationofnanoporousSiO2 areogelatambientpressure 显示文摘NiXY ZhangZH HuangYD etal 2004JouranlofFunctionalMaterialsContents2004,35,1:1
3邂逅美人夏布利显示文摘夏布利(Chablis)只用霞多丽(Chardonnay)这一个葡萄品种酿酒,但通常没有被称为霞多丽,而拥有一个专属的品名。因为夏布利的确是一种独特的酒。夏布利酒有标志性的矿物风味,通常还有花香,以及柑橘类水果以及白肉水果气息。清冽可口,高雅纯粹,构架精致,像一个骨感美人。Nixy 2015葡萄酒2015,0,6:0
4Bromocriptine protects perilesional spinal cord neurons from lipotoxicity after spinal cord injury显示文摘Recent studies have revealed that lipid droplets accumulate in neurons after brain injury and evoke lipotoxicity,damaging the neurons.However,how lipids are metabolized by spinal cord neurons after spinal cord injury remains unclear.Herein,we investigated lipid metabolism by spinal cord neurons after spinal cord injury and identified lipid-lowering compounds to treat spinal cord injury.We found that lipid droplets accumulated in perilesional spinal cord neurons after spinal cord injury in mice.Lipid droplet accumulation could be induced by myelin debris in HT22 cells.Myelin debris degradation by phospholipase led to massive free fatty acid production,which increased lipid droplet synthesis,β-oxidation,and oxidative phosphorylation.Excessive oxidative phosphorylation increased reactive oxygen species generation,which led to increased lipid peroxidation and HT22 cell apoptosis.Bromocriptine was identified as a lipid-lowering compound that inhibited phosphorylation of cytosolic phospholipase A2 by reducing the phosphorylation of extracellular signal-regulated kinases 1/2 in the mitogen-activated protein kinase pathway,thereby inhibiting myelin debris degradation by cytosolic phospholipase A2 and alleviating lipid droplet accumulation in myelin debris-treated HT22 cells.Motor function,lipid droplet accumulation in spinal cord neurons and neuronal survival were all improved in bromocriptine-treated mice after spinal cord injury.The results suggest that bromocriptine can protect neurons from lipotoxic damage after spinal cord injury via the extracellular signal-regulated kinases 1/2-cytosolic phospholipase A2 pathway.Ying Peng Zhuoxuan Li Zhiyang Zhang Yinglun Chen Renyuan Wang Nixi Xu Yuanwu Cao Chang Jiang Zixian Chen Haodong Lin 2024Neural Regeneration Research2024,19,5:0
5期酒,作为一种金融产品显示文摘尽管期酒涉及的酒款绝大多数来自法国,主要的期酒的交易所却在英吉利海峡对面,在作为欧洲金融中心的伦敦。现在法国的名庄酒已经高度金融化,在一级市场上几乎完全以期权的形式交易。Nixy 2015葡萄酒2015,0,5:0
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