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| 1 | Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages. | Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，3： | 3 |
| 2 | Corrosion rate determination of rare-earth Mg alloys in a Na_(2)SO_(4)solution by electrochemical measurements and inductive coupled plasma-optical emission spectroscopy显示文摘The corrosion resistance of three Mg alloys containing rare-earth elements(WE43,EV31 and ZE41)was studied and compared to that of two Mg-Al alloys(AZ31 and AZ91)and of pure Mg(99.95 wt.%).Current-voltage curves and electrochemical impedance measurements were performed with rotating disk electrodes in an aerated 0.1 M Na_(2)SO_(4)solution.For all the alloys,it was confirmed that the intermetallic particles acted as local cathodes and that more protective films were formed on the alloys surface by comparison with the pure Mg.Corrosion rates were determined from inductive coupled plasma-optical emission spectroscopy measurements and from the electrochemical measurements.Higher corrosion rates were observed for the rare-earth Mg alloys compared to the AZ series alloys.These data allowed the corrosion mechanisms to be discussed. | Samuel Leleu Bertrand Rives Nicolas Causse Nadine Pébère | 2019 | Journal of Magnesium and Alloys2019，7，1： | 3 |
| 3 | Potential stem cell marker CD44 is constitutively expressed in permanent cell lines of head and neck cancer显示文摘 | Ralph P Nadine W Thomas T | 2008 | In Vivo2008，22，1： | 1 |
| 4 | Memory and midazolam conscio sedation 显示文摘 | Nadin G Coulthard P | 1997 | Br Dent J1997，183，： | 1 |
| 5 | The corrosion of pure magnesium in aerated and deaerated sodium sulphate solutions显示文摘 | Genevieve B Nadine P | 2001 | Corrosion Science2001，43，2： | 1 |
| 6 | Study of the synergistic observed for the corrosion protection of a carbon steel by an association of phosphates显示文摘 | Trinh Anh Truc Nadine P eb ere To Thi Xuan Hang | 2002 | Corrosion Science2002，44，： | 1 |
| 7 | Reservoir quality variation on an Eocene carbonate ramp, EI Garia Formation, offshore Tunisia: Structural eontrol of burial corrosion and dolomitisation显示文摘 | Nadin P Clarke E Jonathan M | 2008 | Sedimentary Geology2008，209，： | 1 |
| 8 | Isolation and characterization of mesenchymal stem cells from adult mouse bone marrow显示文摘 | Philippe T Daniele N Nadine P | 2004 | Exper Cell Res2004，295，2： | 1 |
| 9 | Isolation and characterization of mesenchymal stem cells from adult mouse bone marrow 显示文摘 | Phippe T Daniele Nadine P | 2004 | Exp Cell Res2004，295，2： | 1 |
| 10 | Memory and midazolam conscious sedation显示文摘 | Nadin G Coulthard P | 1997 | Br Dent J1997，183，1112： | 1 |
| 11 | Reservoir quality variation on an Eocene carbonate ramp, EI Garia Formation, offshore Tunisia: Structural controlof burial corrosion and dolomitisation显示文摘 | Nadin P Clarke E Jonathan M | 2008 | Sedimenta- ry Geology2008，209，： | 1 |
| 12 | The corrosion of pure magnesium in aerated and deaerated sodium sulphate solutions显示文摘 | Geneviève Baril Nadine Pébère | 2001 | Corrosion Science2001，，3： | 1 |
| 13 | Reservoir quality variation in an Eocene carbonate ramp,El Garia Formation, offshore Tunisia:Structural control of burial corrosion and dolomitisation 显示文摘 | Beavington-Penney S J Nadin P Wright V P | 2008 | Sedimentary Geology2008，209，1： | 1 |
| 14 | The corrosion of pure magnesi um in aerated and deaerated sodium sulphate solution 显示文摘 | Genevieve B Nadine P | 2001 | Corrosion Science2001，43，： | 1 |
| 15 | Electrochemical characterisation of a martensitic stainless steel in a neutral chloride solution显示文摘 | Sabrina Marcelin Nadine Pébère Sophie Régnier | 2013 | Electrochimica Acta2013，，： | 1 |
| 16 | FESEM and EIS study of sealed AA2024 T3 anodized in sulfuric acid electrolytes:influence of tartaric acid 显示文摘 | Gregory B Nadine P Catherine D | 2008 | Journal of the Electrochemical Society2008，155，11： | 1 |
| 17 | Evaluation of corrosion performance of a UV-cured polyurethane coating in the presence of organic phosphorous compounds显示文摘 | TRINH ANH TRUC NADINE PéBèRE TO THI XUAN HANG | | 0，，： | 1 |
| 18 | Inactivation Kinetics of Spores of Bacillus cereus Strains Treated by a Peracetic Acid-Based Disinfectant at Different Concentrations and Temperatures显示文摘 | Nadine S Maria Consuelo P | 2012 | Foodborne Pathogens And Disease2012，9，5： | 1 |
| 19 | FESEM and EIS study of sealed AA2024 T3 anodized in sulfuric acid electrolytes:Influence of tartaric acid显示文摘 | GRéGORY B NADINE P CATHERINE D MARTINE V STEPHANE S | 2008 | Journal of the Electrochemical Society2008，155，11： | 1 |
| 20 | The corrosion of pure magnesium in aerated and deaerated sodium sulphate solutions 显示文摘 | GENEVIEVE B NADINE P | 2001 | Corrosion Science2001，43，： | 1 |
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