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	题名	作者	年代	出处	被引量
1	Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy显示文摘AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn’s disease(CD)and ulcerative colitis(UC).METHODS:The data from 41 patients with CD and 22 patients with UC were assessed.Twenty-four CD patients received infliximab,and 17 received adalimumab.The endoscopic severity of CD was quantified with the simplified endoscopic activity score for Crohn’s disease in CD and with the Mayo endoscopic subscore in UC.RESULTS:Mucosal healing was achieved in 23 CD and7 UC patients.Biological therapy had to be restarted in78%of patients achieving complete mucosal healing with CD and in 100%of patients with UC.Neither clinical remission nor mucosal healing was associated with the time to restarting the biological therapy in either CD or UC.CONCLUSION:Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped.	Klaudia Farkas Péter László Lakatos Mónika Szcs va Pallagi-Kunstár Anita Bálint Ferenc Nagy Zoltán Szepes Noémi Vass Lajos S Kiss Tibor Wittmann Tamás Molnár	2014	World Journal of Gastroenterology2014，20，11：	2
2	Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation显示文摘	Céline Chu Marie‐Sophie No?l‐Hudson Valérie Boige Diane Goéré Sylvie Marion Mélanie Polrot Ludovic Bigot Patrick Gonin Robert Farinotti Laurence Bonhomme‐Faivre	2013	Fundamental & Clinical Pharmacology2013，，4：	2
3	Atherosclerotic burden findings in young cryptogenic stroke patients with and without a patent foramen ovale显示文摘	Rod s-Cabau J No l M Marrero A	2009	Stroke2009，40，2：	1
4	Mammalian five ADNFLE mutations reduce Ca^2+ dependence of the {alpha}4 {beta}2 acetylcholine response显示文摘	Rodrigues-Pinguet NO Jia L Li M	2003	J Physiol2003，550，1：	1
5	Influence of Al and Ni concentration on the martensitic transformation in Cu Al Ni shape-memory alloys 显示文摘	RECARTE V PEREZ-SAEZ R B BOCANEGRA E H NO M L SAN JUAN J	2002	Metall Mater Trans A2002，33，：	1
6	Comparison of knowledge, attitudes and behaviour regarding smoking among Estonian and Finnish physicians显示文摘	Kersti P?rna Kaja Rahu No?l C. Barengo Mati Rahu Patrick H. Sandstr?m Vesa J. Jormanainen Markku T. Myllykangas	2005	Sozial - und Pr?ventivmedizin SPM2005，，6：	1
7	Sott-tissue sarcomas and exposure to chemical substances: a case- referent study显示文摘	Eriksson M Hardell L Berg NO	1981	Br J Ind Med1981，43，2：	1
8	African swine fever(ASF):five years around Europe显示文摘	Sánchez-Vizcaíno J M Mur L Martínez-López B	2013	Veterinary Microbiology2013，165，：	1
9	Effects of the microalga Scenedesmus almeriensis as fishmeal alternative in diets for gilthead sea bream, Sparus aurata, juveniles 显示文摘	Vizcaíno A J López G Sáez M I	2014	Aquaculture2014，431，：	1
10	In situ of the β phase decomposition process in a Cu-al-Ni shape memory alloy processed by powder metallurgy 显示文摘	RECARTE V PEREZ-LANDAZABAL J I CAMPO J PEREZ-SAEZ R B NO M L SAN JUAN J	2003	Journal De Physique IV:JP2003，112，：	1
11	Matrix metalloproteinases at cancer tumor-host interface显示文摘	No(e)l A Jost M Maquoi E	2008	Semin Cell Dev Biol2008，19，1：	1
12	A new fluorimetric assay for cytotoxity measurements in vitro显示文摘	Pagé B Pagé M Noèl C	1993	International Journal of Oncology1993，3，：	1
13	Biological monitoring of occupa- tional exposure to N, N-dimethylacetamide with identify cation of a new metabolite显示文摘	PERBELL1NI L PRINCIVALLE A CAIVA- NO M	2003	Occup Environ Med2003，60，10：	1
14	Extrapulmonary infections due to Mycoplasma pneumoniae显示文摘	Garnier J M No l G Retornaz K	2005	Arch Pediatr2005，12，1：	1
15	Glucagon-like peptide- 1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum显示文摘	blANSEN L HARTMANN B M/NO H	2004	Regul Pept2004，118，：	1
16	Time-temperature profiles of chilled ready-to-eat foods in school catering and prob- abilistic analysis of Listeria monocytogenes growth显示文摘	ROSSET P CORNU M NO C E L V	2004	Interna- tional Journal of Food Microbiology2004，96，1：	1
17	Damping behavior during martensitic transformation in shape memory alloys显示文摘	JUAN J S NO M L	2003	Journal of Alloys and Compounds2003，355，1：	1
18	Cellular neural networks and active contours: a tool for image segmentation显示文摘	Vilari no D L Cabello D Pardo X M	2003	Image and Vision Computing2003，21，2：	1
19	Effect of ball milling parameters on the microstructure of W-Y powders and sintered sample 显示文摘	Avettand-F~no~l M N Taillard R Dhers J	2003	International Journal of Refractory Metals Hard Materials2003，21，34：	1
20	Radiosensitization by the poly (ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis显示文摘	No(e)l G Godon C Femet M		0，，：	1

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