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| 1 | 针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。 | Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) | 2020 | 英国医学杂志中文版2020，23，9： | 5 |
| 2 | Association mapping: critical considerations shift from genotyping to experimental design 显示文摘 | Myles S Peiffer J Brown P J Ersoz E S Zhang Z Costich D E Buckler E S | 2009 | The Plant Cell Online2009，21，8： | 1 |
| 3 | Regional anaesthesia and pain management显示文摘 | Power I Mc Cormack J G Myles P S | 2010 | Anaesthesia2010，，： | 1 |
| 4 | Bispectral index monitoring to prevent awareness during anaesthesia:the B-Aware randomised con trolled trial显示文摘 | Myles P Leslie K McNeil J | 2004 | Lancet2004，363，： | 1 |
| 5 | A randomised controlled trial of BIS monitoring to prevent awareness during anaesthesia:The B-A-ware Trial显示文摘 | Myles P Leslie K McNeil J | 2004 | Lancet2004，363，： | 1 |
| 6 | Myocardial protection with volatile anaesthetic agent during coronary artery bypass surgery: a meta-analysis 显示文摘 | SYMONS J A MYLES P S | 2006 | Br J Anaesth2006，97，2： | 1 |
| 7 | Associa- tion mapping: critical considerations shift from genoty- ping to experimental design 显示文摘 | MYLES S PEIFFER J BROWN P J | 2009 | Plant Cell2009，21，8： | 1 |
| 8 | Using the Bland-Altman method to measure agreement with measures显示文摘 | MYLES P S CUI J | 2007 | Br J Anaesth2007，99，3： | 1 |
| 9 | Remifentanil,fentanyl,and cardiac surgerry,a double-blinded,randomized,controlled trial of costs and out comes显示文摘 | Myles P S Hunt J Fletcher H | 2002 | Anesth Analg2002，95，4： | 1 |
| 10 | A mndomised controlled trial of BIS monitoring to prevent awareness during anaesthesia:The BAware Trial显示文摘 | Myles P Leslie K McNeil J | 2004 | Lancet2004，363，： | 1 |
| 11 | Bayesian evaluation of breast cancer screening using data from two studies显示文摘 | Myles J P Nixon R M Duffy S W | 2003 | Stat Med2003，22，10： | 1 |
| 12 | Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial显示文摘 | MYLES P S LESLIE K MCNEIL J | 2004 | Lancet2004，363，9423： | 1 |
| 13 | Epidual anaesthesia and analgesia and outcome of major surgery:a randomized trial显示文摘 | Rigg J R A Jamrozick K Myles P S | 2002 | Lancet2002，359，： | 1 |
| 14 | Quality and safety indicators in anesthesia显示文摘 | Hailer G Stoelwinder J Myles P | 2009 | Anesthesiology2009，110，： | 1 |
| 15 | Intraeranial hemorrhage in neonates with unrecognized hemophilia A: a persisting problem显示文摘 | MYLES LM MASSICOTTE P DRAKE J | 2001 | Pediatric Neurosurgery2001，34，： | 1 |
| 16 | Epidural anaesthesia and analgesia and outcome of major surgery: a randomized trial 显示文摘 | Rigg J R Jamrozik K Myles P S | 2002 | Lancet2002，359，6： | 1 |
| 17 | Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial 显示文摘 | MYLES P S LESLIE K MCNEIL J | 2004 | Lancet2004，363，9423： | 1 |
| 18 | Prehospital hypertonic saline resuscitation of patients withhypotension and severe traumatic brain injury : a randomizedcontrolled trial显示文摘 | COOPER D J MYLES P S MCDERMOTT F T | 2004 | JAMA2004，291，11： | 1 |
| 19 | Bispectral index mo- nitoring to prevent awareness during anaesthesia: The B-A- ware randomised controlled trial 显示文摘 | Myles P S Leslie K McNeil J | 2004 | Lancet2004，363，9423： | 1 |
| 20 | Bispectral index monitoring to prevent awareness during anaesthesia: the B-aware randomised controlled trial显示文摘 | Myles P S Leslie K McNeil J | 2004 | Lancet2004，363，9243： | 1 |
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