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34篇 您的检索式：作者名="Mulder HJ"

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	题名	作者	年代	出处	被引量
1	On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprineor 6-mercaptopurine intolerant IBD patients显示文摘AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) or 6-mercaptopurine (6-MP) intolerant inflammatory bowel disease (IBD) patients over a treatment period of at least 1 year.METHODS: Database analysis.RESULTS: Twenty out of ninety-five (21%) patients discontinued 6-TG (mean dose 24.6 mg; mean 6-TGN level 540 pmol/8×108 RBC) within 1 year. Reasons for discontinuation were GI complaints (31%), malaise (15%)and hepatotoxicity (15%). Hematological events occurred in three patients, one discontinued treatment. In the 6-TG-tolerant group, 9% (7/75) could be classified as hepatotoxicity. An abdominal ultrasound was performed in 54% of patients, one patient had splenomegaly.CONCLUSION: The majority of AZA or 6-MP-intolerant IBD patients (79%) is able to tolerate maintenance treatment with 6-TG (dosages between 0.3 and 0.4 mg/kg per d). 6-TG may still be considered as an escape maintenance immunosuppressant in this difficult to treat group of patients, taking into account potential toxicity and efficacy of other alternatives. The recently reported hepatotoxicity is worrisome and 6-TG should therefore be administered only in prospective trials.	Nanne KH de Boer Luc JJ Derijks Lennard PL Gilissen Daniel W Hommes Leopold GJB Engels Sybrand Y de Boer Gijsbertus den Hartog Piet M Hooymans Anja BU M(?)kelburg Barend D Westerveld Anton HJ Naber Chris JJ Mulder Dirk J de Jong	2005	World Journal of Gastroenterology2005，11，35：	4
2	Anterior mediastinal presentation of a gianl angiomyolipoma显示文摘	Amir AM Zeebregts CJ Mulder HJ	2004	Ann Thorac Surg2004，78，6：	1
3	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty(REGRESS trial)显示文摘	Mulder HJ Bal ET Jukema JW Zwinderman AH Schalij MJ van Boven AJ	2000	Am J Cardiol2000，86，7：	1
4	Improvement of tidal breathing pattern analysis in children with asthma by on-line automatic data processing显示文摘	Van der Ent CK Brackel HJ Mulder P	1996	European Respiratory Journal1996，9，6：	1
5	Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin 显示文摘	Mulder AB Van Lijf HJ Bon MA	2001	Clin Pharmacol Ther2001，0，6：	1
6	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty ( REGRESS trial) 显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，7：	1
7	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial) 显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，：	1
8	Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerabihty of simvastatin显示文摘	Mulder AB Van Lijf HJ Bon MA	2001	Clin Pharmacol Ther2001，70，6：	1
9	Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin 显示文摘	MULDER AB V AN LIJF HJ BON MA	2001	Clin Pharmacol Ther2001，70，6：	1
10	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial) 显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，7：	1
11	Improvement of tidal breathing pattern analysis in children with asthma by on-line automatic data processing 显示文摘	van der Ent CK Brackel HJ Mulder P	1996	Eur Respir J1996，9，6：	1
12	Anterior mediastinal presentation of a giant angiomyolipoma显示文摘	Amir AM Zeebregts CJ Mulder HJ	2004	Ann Thorae Surg2004，78，6：	1
13	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial) 显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，7：	1
14	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial)显示文摘	Mulder HJ Bal ET	2000	Am J Cardiol2000，86，：	1
15	In vitro adhesion to enamel and in vivo colonization of tooth surfaces by lactobacilli from a bio-yoghurt显示文摘	Busscher HJ Mulder A van der Mei HC	1999	Caries Res1999，33，5：	1
16	Association of polymorphism in the cytochrome CYP2D6 and the efficacy and to lerability of simvastatin 显示文摘	Mulder AB Van HJ Bon M	2001	Clin Pharmacal Ther2001，70，：	1
17	Changes in Farr radioimmunoassay and EllA fluorescence immunoassay anti- dsDNA in relation to exacerbation of SLE显示文摘	Hillebrand JJ Moens HJ Mulder AH	2013	Lupus2013，22，11：	1
18	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty(REGRESS trial)显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，7：	1
19	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial)显示文摘	Mulder HJ Bal ET Jukema JW	2000	Am J Cardiol2000，86，7：	1
20	Pravastatin reduces restenosis two years after percutaneous transluminal coronary angioplasty (REGRESS trial)显示文摘	Mulder HJ Bal ET	2000	Am J Cardiol2000，86，：	1

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