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2篇 您的检索式:作者名="Mosaad Megahed"
    题名 作者 年代 出处 被引量
1Hepatitis C virus-mediated angiogenesis:Molecular mechanisms and therapeutic strategies显示文摘Angiogenesis is an essential process for organ growth and repair. Thus, an imbalance in this process can lead to several diseases including malignancy. Angiogenesis is a critical step in vascular remodeling, tissue damage and wound healing besides being required for invasive tumor growth and metastasis. Because angiogenesis sets an important point in the control of tumor progression, its inhibition is considered a valuable therapeutic approach for tumor treatment. Chronic liver disease including hepatitis C virus(HCV) infection is one of the main cause for the development of hepatic angiogenesis and thereby plays a critical role in the modulation of hepatic angiogenesis that finally leads to hepatocellular carcinoma progression and invasion. Thus, understanding of the molecular mechanisms of HCV-mediated hepatic angiogenesis will help design a therapeutic protocol for the intervention of HCV-mediated angiogenesis and subsequently its outcome. In this review, we will focus on the molecular mechanisms of HCV-mediated hepatic angiogenesis and the related signaling pathways that can be target for current and under development therapeutic approaches.Mohamed Hassan Denis Selimovic Abdelouahid El-Khattouti Martine Soell Hanan Ghozlan Youssef Haikel Ola Abdelkader Mosaad Megahed 2014World Journal of Gastroenterology2014,20,42:1
2CD133 + melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: Significance for melanoma treatment显示文摘Abdelouahid El-Khattouti Natale T. Sheehan Jesus Monico Heather A. Drummond Youssef Haikel Robert T. Brodell Mosaad Megahed Mohamed Hassan 2014Cancer Letters2014,,:1
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